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| 1 | Loss of gonadal soma derived factor damaging the pituitary-gonadal axis in medaka显示文摘Medaka sex is determined by dmy/dmrt1b Y,the doublesex and mab-3 domain gene on the Y chromosome[1,2].Most recent studies have revealed a germ cell-intrinsic cue for the sperm-egg fate decision present in medaka,leading to spermatogenesis occurrence in a female gonadal environment without the presence of dmy[3].Targeted disruption of dmy,or sex related genes,such | Kaiqing Sun Lidong Fan Chuanyun Wang Xiaoyu Yang Shuangguang Zhu Xi Zhang Xiaowu Chen Yunhan Hong Guijun Guan | 2017 | Science Bulletin2017，62，3： | 4 |
| 2 | Sexually dimorphic expression of types of DM(Doublesex/Mab- 3)--Donna genes in a teleost Fish, the Tilapia(Oreoehromis niloticus)显示文摘 | Guijun Guan Tohru Kobayashi Yoshitaka Nagahama | 2000 | Biochemical and Biophysical Research in Communications2000，272，3： | 1 |
| 3 | Sexually Dimorphic Expression of Types of DM (Doublesex/Mab-3)-Domain Genes in a Teleost Fish, the Tilapia(Oreochromis niloticus) 显示文摘 | Guijun Guan Tohru Kobayashi Yoshitaka Nagahama | 2002 | Biochemical and Biophysical Research in Communications2002，72，： | 1 |
| 4 | Sexually dimorphic expression of types of DM (Doublesex/Mab-3)-Domain genes in a teleost Fish,the Tilapia (Oreochromis niloticus)显示文摘 | Guijun Guan Tohru Kobayashi Yoshitaka Nagahama | 2000 | Biochemical and Biophysical Research in Communications2000，272，3： | 1 |
| 5 | Sexually Dimorphic Expression of Two Types of DM ( Doublesex/Mab-3 )-Domain Genes in a Teleost Fish, the Tilapia ( Oreochromis niloticus )显示文摘 | Guijun Guan Tohru Kobayashi Yoshitaka Nagahama | 2000 | Biochemical and Biophysical Research Communications2000，，3： | 1 |
| 6 | Crystal-orientation controlled epitaxial CeO2 dielectric thin films on Si(100) substrates using pulsed !aser deposition 显示文摘 | Kang Jinfeng Liu Xiaoyan Lian Guijun Zhang Zhaohui Xiong Guangcheng Guan Xudong Han Ruqi Wang Yangyuan | 2001 | Micro- electronic Engineering2001，56，12： | 1 |
| 7 | Physical Activity,Sedentary Behavior,and the Risk of Cardiovascular Disease in Type 2 Diabetes Mellitus Patients:The MIDiab Study显示文摘The aim of this study was to explore the associations of moderate-to-vigorous-intensity physical activity(MVPA)time and sedentary(SED)time with a history of cardiovascular disease(CVD)and multifactorial(i.e.,blood pressure(BP),body mass index(BMI),low-density lipoprotein cholesterol(LDL-C),and glycated hemoglobin A1c(HbA1c))control status among type 2 diabetes mellitus(T2DM)patients in China.A cross-sectional analysis of 9152 people with type 2 diabetes from the Multifactorial Intervention on Type 2 Diabetes(MIDiab)study was performed.Patients were grouped according to their self-reported MVPA time(low,<150 min·week−1;moderate,150 to<450 min·week−1;high,≥450 min·week−1)and SED time(low,<4 h·d–1;moderate,4 to<8 h·d–1;high,≥8 h·d–1).Participants who self-reported a history of CVD were identified as having a CVD risk.Odds ratios(ORs)and 95%confidence intervals(CIs)of CVD risk and multifactorial control status associated with MVPA time and SED time were estimated using mixed-effect logistic regression models,adjusting for China’s geographical region characteristics.The participants had a mean±standard deviation(SD)age of(60.87±8.44)years,44.5%were women,and 25.1%had CVD.After adjustment for potential confounding factors,an inverse association between high MVPA time and CVD risk that was independent of SED time was found,whereas this association was not observed in the moderate-MVPA group.A higher MVPA time was more likely to have a positive effect on the control of BMI.Compared with the reference group(i.e.,those with MVPA time≥450 min·week−1 and SED time<4 h·d–1),CVD risk was higher in the low-MVPA group:The OR associated with an SED time<4 h·d–1 was 1.270(95%CI,1.040–1.553)and that associated with an SED time≥8 h·d–1 was 1.499(95%CI,1.149–1.955).We found that a high MVPA time(i.e.,≥450 min·week−1)was associated with lower odds of CVD risk regardless of SED time among patients with T2DM. | Yafei Wu Guijun Qin Guixia Wang Libin Liu Bing Chen Qingbo Guan Zhongshang Yuan Xu Hou Ling Gao Chao Xu Haiqing Zhang Xu Zhang Qiu Li Yongfeng Song Fei Jing Shizhan Ma Shanshan Shao Meng Zhao Qingling Guo Nanwei Tong Hongyan Zhao Xiaomin Xie Chao Liu Zhongyan Shan Zhifeng Cheng Xuefeng Yu Shulin Chen Tao Yang Yangang Wang Dongmei Li Zhaoli Yan Lixin Guo Qiuhe Ji Wenjuan Wang Jiajun Zhao | 2023 | Engineering2023，，1： | 1 |
| 8 | Animal Safety Test of Bacillus thuringiensis BT Protein显示文摘[Objectives]To determine the biological safety of BT protein from Bacillus thuringiensis(Bt)fermentation broth to mammals at high doses.[Methods]Healthy mice were randomly divided into 4 groups with 10 mice in each group.The experimental groups were fed with Bt fermentation supernatant at 0.2,0.6 and 1.0 mL/kg,respectively,once a day for 7 consecutive days.The blank control group was fed normally without intragastric administration.[Results]There was no significant difference in blood routine and blood biochemical analysis between the experimental group and the control group.After intragastric administration,the mice were dissected,and no obvious pathological changes were found;the heart,liver,spleen,lung and kidney were taken to make tissue sections,and no pathological changes were found by microscopic observation.[Conclusions]Mice can tolerate high doses of BT protein from B.thuringiensis fermentation broth. | Weimeng NING Dingkuo LIU Fang LIU Yuan LI Xiaowei YANG Zhenguo GUAN Guijun YANG Bo ZHANG Pengcheng HU | 2024 | Asian Agricultural Research2024，16，2： | 0 |
| 9 | Highly efficient ozone elimination by metal doped ultra-fine Cu_(2)O nanoparticles显示文摘Nowadays,ozone contamination becomes dominant in air and thus challenges the research and development of cost-effective catalyst.In this study,metal doped Cu_(2)O catalysts are synthesized via reduction of Cu^(2+)by ascorbic acid in base solutions containing doping metal ions.The results show that compared with pure Cu_(2)O,the Mg^(2+)and Fe^(2+)dopants enhance the O_(3)removal efficiency while Ni2+depresses the activity.In specific,Mg-Cu_(2)O shows high O3removal efficiency of 88.4%in harsh environment of 600,000 mL/(g·hr) space velocity and 1500 ppmV O_(3),which is one of the highest in the literature.Photoluminescence and electron paramagnetic spectroscopy characterization shows higher concentration of crystal defects induced by the Mg^(2+)dopants,favoring the O3degradation.The in-situ diffuse reflectance Fourier transform infrared spectroscopy shows the intermediate species in the O_(3)degradation process change from O_(2)^(2-)dominant of pure Cu_(2)O to O_(2)^(-)dominant of Mg-Cu2O,which would contribute to the high activity.All these results show the promising prospect of the Mg-Cu_(2)O for highly efficiency O_(3)removal. | Anqi Wang Le Zhang Jian Guan Xiaoze Wang Guojun Ma Guijun Fan Hang Wang Ning Han Yunfa Chen | 2023 | Journal of Environmental Sciences2023，，12： | 0 |
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