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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Current trends of liver cirrhosis in Mexico: Similitudes and differences with other world regions显示文摘AIM To investigate the main current etiologies of cirrhosis in Mexico.METHODS We performed a cross-sectional retrospective multicenter study that included eight hospitals in different areas of Mexico. These hospitals provide health care to people of diverse social classes. The inclusion criteria were a histological, clinical, biochemical, endoscopic, or imaging diagnosis of liver cirrhosis. Data were obtained during a 5-year period(January 2012-December 2017). RESULTS A total of 1210 patients were included. The mean age was 62.5 years(SD = 12.1), and the percentages of men and women were similar(52.0% vs 48.0%). The most frequent causes of liver cirrhosis were hepatitis C virus(HCV)(36.2%), alcoholic liver disease(ALD)(31.2%), and nonalcoholic steatohepatitis(23.2%), and the least frequent were hepatitis B virus(1.1%), autoimmune disorders(7.3%), and other conditions(1.0%).CONCLUSION HCV and ALD are the most frequent causes of cirrhosis in Mexico. However, we note that non-alcoholic fatty liver disease(NAFLD) as an etiology of cirrhosis increased by 100% compared with the rate noted previously. We conclude that NAFLD will soon become one of the most frequent etiologies of liver cirrhosis in Mexico. | Nahum Méndez-Sánchez Felipe Zamarripa-Dorsey Arturo Panduro Emma Purón-González Edgar Ulises Coronado-Alejandro Carlos Alejandro Cortez-Hernández Fátima Higuera de la Tijera José Luis Pérez-Hernández Eira Cerda-Reyes Heriberto Rodríguez-Hernández Vania César Cruz-Ramón Oscar Lenin Ramírez-Pérez Nancy Edith Aguilar-Olivos Olga Fabiola Rodríguez-Martínez Samantha Cabrera-Palma Guillermo Cabrera-álvarez | 2018 | World Journal of Clinical Cases2018，6，15： | 2 |
| 3 | Local recurrence after masteetomy for breast cancer:analysis of clinicopatho logical, biological and prognostic characteristics显示文摘 | Guillermo C Jose M Daniela C | 2007 | Breast Cancer Res Treat2007，102，1： | 1 |
| 4 | Ovarian and extraovarian endometriosis-associated cancer显示文摘 | Susan C Modesitt Guillermo Tortolero-Luna Jubilee B Robinson David M Gershenson Judith K Wolf | 2002 | Obstetrics & Gynecology2002，，： | 1 |
| 5 | Effect of illumination and chlorophylls on stability of tomato carotenoids显示文摘 | Marts M C Guillermo S M | 2008 | Food Chemistry2008，107，4： | 1 |
| 6 | AFRI, FibroScan, ELF, and their combinations in the assessment of liver fibrosis: a pro- spective study显示文摘 | Gorzalo C Guillermo FV Zoe M | 2012 | J Hepatol2012，57，2： | 1 |
| 7 | Char- acterisation of NMHCs in a French urban atmosphere: overview of the main sources 显示文摘 | Borbon A Locoge N Veillerot M Galloo J C Guillermo B | 2002 | The Science of the Total Environment2002，292，3： | 1 |
| 8 | Hydrogenation of edible oil, over Pd catalysts: A combined theoretical and experimental study显示文摘 | Maria B F Gabriela M T Guillermo H C | 2005 | Journal of Molecular Catalysis A : Chemical2005，237，2： | 1 |
| 9 | Assessment of bioavailable arsenic and copper in soils and sediments from the Antofagasta region of northern Chile显示文摘 | Helen C F Verna M M Guillermo C D | 2002 | Science of the Total Environment2002，286，： | 1 |
| 10 | Critically ill patients with 2009 influenza A ( H1N1 ) in Mexico 显示文摘 | GUILLERMO D C STEPHEN E LAPINSKY M B | 2009 | JAMA2009，302，17： | 1 |
| 11 | suggested improvements to the standard filter paper assay used to measure cellulase activity显示文摘 | Guillermo C K Cateryna A M Sehoon K | 2002 | Communication to the editor2002，，： | 1 |
| 12 | Revised phylogeny of whales suggested by mitochondrial ribosomal DNA sequences显示文摘 | Milinkovitch M C Guillermo O Meyer A | 1993 | Nature1993，361，： | 1 |
| 13 | Pesticide residue analysis by RPLC-GC in lycopene and other carotenoids obtained from tomatoes by supercritical fluid extraction显示文摘 | JOSE M C ANA V GUILLERMO S M | 2009 | Food Chemistry2009，113，： | 1 |
| 14 | Polymorphisms of antioxidant enzymes, blood pressure and risk of hypertension显示文摘 | María L Mansego Griselda De Marco Solar Mónica Pineda Alonso Fernando Martínez Guillermo T Sáez Juan C Martin Escudero Josep Redón Felipe J Chaves | 2011 | Journal of Hypertension2011，，3： | 1 |
| 15 | Acute phase protein concentrations in retired racing Greyhounds显示文摘 | C Guillermo Couto Jose J Ceron Parra M D | 2009 | Veterinary Clinical Pathology2009，38，2： | 1 |
| 16 | An Overview of Progress and Current Challenges in Ultrasonic Treatment of Polymer Melts显示文摘 | Carlos A O Carlos E G Guillermo M C | 2013 | Advances in Polymer Technology2013，，： | 1 |
| 17 | 查看详情显示文摘 | Jose M C Ana V Guillermo S M | | 0，，： | 1 |
| 18 | Critically ill patients with 2009 influenza A (H1N1) in Mexico显示文摘 | GUILLERMO D C STEPHEN E LAPINSKY M B | 2009 | JAMA2009，302，： | 1 |
| 19 | Long-term results of the treatment of Hodgkin’s lymphoma in a resource-constrained setting:Real-world data from a single center显示文摘BACKGROUND The outcomes of Hodgkin's lymphoma(HL)in Mexico have not been widely reported.Simplified and affordable treatments have been adopted in middleincome countries.AIM The aim was to evaluate long-used therapies for HL in Mexico in a long-term basis.METHODS In a 34-year time period,88 patients with HL were treated at a single institution in Mexico.Patients were treated with adriamycin bleomycin vinblastine and dacarbazine(ABVD)or mechlorethamine,vincristine,procarbazine,and prednisone(MOPP).Relapsed or refractory patients were given ifosfamide,carboplatin,and etoposide(ICE)followed by autologous or allogeneic stem cell transplants.RESULTS Thirty-seven women and 51 men were included;the median age was 29 years.Patients were followed for a mean of 128 mo.The 310-mo overall survival(OS)was 83%for patients treated with MOPP and 88%for those treated with ABVD.The OS of patients who received autologous stem cell transplantation was 76%(330 mo)vs 93%(402 mo)in those who did not.CONCLUSION HL may be less aggressive in Mexican population than in Caucasians.Combined chemotherapy renders acceptable results,regardless of clinical stage. | Luisa Fernanda Sánchez-Valledor Thomas M Habermann Iván Murrieta-Alvarez Alejandra Carmina Córdova-Ramírez Montserrat Rivera-Álvarez Andrés León-Peña Yahveth Cantero-Fortiz Juan Carlos Olivares-Gazca Guillermo JoséRuiz-Delgado Guillermo JoséRuiz-Argüelles | 2021 | World Journal of Clinical Oncology2021，12，9： | 0 |
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