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| 1 | Jagged-1/Notch3 signaling transduction pathway is involved in apelin-13-induced vascular smooth muscle cells proliferation显示文摘apelin/apelin 受体(APJ, apelinangiotensin 像受体 1 ) 系统是一最新 deorphanized G 联合蛋白质的受体系统。是重要规章的因素的 apelin 和 APJ 在心血管的系统被表示。我们的以前的研究显著地表明了那 apelin-13 刺激脉管的光滑的肌肉房间(VSMC ) 增长。在这份报纸,我们的数据建议表明 transduction 小径的 Jagged-1/Notch3 被支持 Cyclin D1 的表示涉及 apelin-13-induced VSMC 增长。结果显示 apelin-13 在集中依赖者和时间依赖者礼貌刺激 VSMC 和 Jagged-1 和 Notch3 的表示的增长。apelin-13 导致的 Jagged-1 和 Notch3 的增加的表示能被细胞外的调整信号的蛋白质 kinase (英皇家空军之阶级最低之兵) 废除封锁。PD98059 (英皇家空军之阶级最低之兵禁止者) 能禁止 apelin-13 导致的 Jagged-1/Notch3 的激活。用小介入 RNA 的 Notch3 的下面规定禁止 Cyclin D1 的表示并且阻止 apelin-13-induced VSMC 增长。在结论, Jagged-1/Notch3 发信号 transduction 小径涉及 apelin-13 导致的 VSMC 增长。 | Lifang Li Lanfang Li Feng Xie Zidong Zhang Yu Guo Guotao Tang Deguan Lv Qixuan Lu Linxi Chen Jian Li | 2013 | Acta Biochimica et Biophysica Sinica2013，45，10： | 18 |
| 2 | The first observation of the atmospheric tides in the mesosphere and lower thermosphere over Hainan, China显示文摘Fuke (19.5°N, 109.1°E) meteor radar is the first radar of the low latitudes of China, which is used to detect the wind in the meso- sphere and lower thermosphere. In this paper, by using the wind data near three months (1 February-20 April, 2009), we first present the variation of the atmospheric diurnal tide, semidiurnal tide and mean wind in the height range 80-100 km over the low latitudes of China. The results from our analysis are summarized below. During spring months, there are quite strong tides in the mesopause region of Fuke. The diurnal tidal amplitude is significantly larger than the amplitude of semidiurnal tide, and the maximum amplitude (about 100 m/s) of diurnal tide appear in the meridional wind. The vertical phases of both diurnal tide and semidiurnal tide propagate downward. In addition, the observed tides are compared with the linear tide model (Global Scale Wave Model, GSWM02), and the results show that Fuke diurnal tide agrees well with the model, but there are many differences between Fuke semidiurnal tide and the results from model. | JIANG GuoYing XU JiYao SHI JianKui YANG GuoTao WANG Xiao YAN ChunXiao | 2010 | Chinese Science Bulletin2010，55，11： | 12 |
| 3 | Lateral control of autonomous vehicles based on learning driver behavior via cloud model显示文摘In order to achieve the lateral control of the intelligent vehicle, use the bi-cognitive model based on cloud model and cloud reasoning, solve the decision problem of the qualitative and quantitative of the lateral control of the intelligent vehicle. Obtaining a number of experiment data by driving a vehicle, classify the data according to the concept of data and fix the input and output variables of the cloud controller, design the control rules of the cloud controller of intelligent vehicle, and clouded and fix the parameter of cloud controller: expectation, entropy and hyper entropy. In order to verify the effectiveness of the cloud controller, joint simulation platform based on Matlab/Simulink/Car Sim is established. Experimental analysis shows that: driver's lateral controller based on cloud model is able to achieve tracking of the desired angle, and achieve good control effect, it also verifies that a series of mental activities such as feeling, cognition, calculation, decision and so on are fuzzy and uncertain. | Gao Hongbo Xie Guotao Liu Hongzhe Zhang Xinyu Li Deyi | 2017 | The Journal of China Universities of Posts and Telecommunications2017，24，2： | 7 |
| 4 | Non-limit passive soil pressure on rigid retaining walls显示文摘This paper aims to reveal the depth distribution law of non-limit passive soil pressure on rigid retaining wall that rotates about the top of the wall(rotation around the top(RT) model). Based on Coulomb theory, the disturbance degree theory, as well as the spring-element model, by setting the rotation angle of the wall as the disturbance parameter, we establish both a depth distribution function for sand and a nonlinear depth distribution calculation method for the non-limit passive soil pressure on a rigid retaining wall under the RT model, which is then compared with experiment. The results suggest that under the RT model: the non-limit soil pressure has a nonlinear distribution; the backfill disturbance degree and the lateral soil pressure increase with an increase in the wall rotation angle; and, the points where the resultant lateral soil pressure acts on the retaining wall are less than 2/3 of the height of the wall. The soil pressure predicted by the theoretical calculation put forward in this paper are quite similar to those obtained by the model experiment, which verifies the theoretical value, and the engineering guidance provided by the calculations are of significance. | Dou Guotao Xia Junwu YU Wenjie Yuan Fang Bai Weigang | 2017 | International Journal of Mining Science and Technology2017，27，3： | 7 |
| 5 | Removal of impurities from scandium chloride solution using 732-type resin显示文摘The deep removal of Al, Fe(Ⅱ/Ⅲ), Ca, Zr, Ti and Si from scandium chloride solution was carried out by using 732-type strong acid cation exchange resin. The effects of pH value, contact time and complexing agents(EDTA) on the purification process are investigated. The results indicate that the 732-type resin have a good scandium selectivity and the adsorption order is Sc > Fe(Ⅲ)>Al > Ca > Zr > Ti > Si in the pH range of 1-3. The separation of Sc and Zr, Si, Ti can be directly carried out because the resin have a good adsorption effect on Sc, AI and Fe(Ⅲ) but poor adsorption effect on Zr, Si and Ti under the condition of pH = 2.5 and contact time 180 min. The Fe(Ⅱ), Ca and Al are selectively adsorbed on the resin by adding reducing agent ascorbic acid and EDTA into the solution for reducing Fe(Ⅲ) to Fe(Ⅱ) and complexing Sc.By using two-step ion exchange adsorption separation method, the removal rates of Fe(Ⅲ), Ti, Al, Ca, Zr and Si are 95.5%,99.8%,100%,98.2%,98.6% and 100%,respectively. | Guotao Zhou Qinggang Li Pan Sun Wenjuan Guan Guiqing Zhang Zuoying Cao Li Zeng | 2018 | Journal of Rare Earths2018，36，3： | 7 |
| 6 | Effects of Tectonic Force on Hydrostatic Pressure in Crust显示文摘The research into the hydrostatic pressure in the crust has been previously conducted from the viewpoint that the hydrostatic pressure is equal to the gravity, based on the fact that the hydrostatic pressure is derived mainly from the gravity of its overlying rocks. In this paper, the stress state of any point in the crust is suggested to have been caused by both the gravity and the tectonic force. The author proposes that the hydrostatic pressure is a combination or superposition of two isotropic stresses in the tectonic force and gravity stress fields. The results obtained with a finite element simulation indicate that the additional hydrostatic pressure borne by rocks decreases gradually from the compression zone ( p s c), the shear zone ( p s sh ) to the tensile zone ( p s t), and that the difference in the additional tectonic hydrostatic pressure between these deformed zones tends to increase, following the increase in the absolute value and/or the difference in external forces between different directions. This paper presents the foundation for the research into the tectonic physicochemistry. | LuGuxian WeiChangshan GuoTao | 2004 | Journal of China University of Geosciences2004，15，2： | 4 |
| 7 | A photocleavable low molecular weight hydrogel for light-triggered drug delivery显示文摘A photocleavable low-molecular-weight hydrogelator (LMWG) was synthesized based on coumarin derivative.~1H NMR and UV spectroscopy study suggested that the gelator had good gelling ability, and the driving force for the gelation were hydrogen bonding and π-π stacking. This molecular hydrogel exhibited satisfied photocleavage at C-N bond in 7-amino coumarin with the light irradiation (365 nm,77.5 mW/cm^2). The promising photo-triggered drug release of antineoplastics cytarabine hydrochloride has been obtained, due to the photocleavage motived gel-sol transition. | Qihong Liu Hao Wang Guotao Li Miaochang Liu Jinchang Ding Xiaobo Huang Wenxia Gao Huayue Wu | 2019 | Chinese Chemical Letters2019，30，2： | 4 |
| 8 | Direct electrochemistry of glucose oxidase on the hydroxyapatite/Nafion composite film modified electrode and its application for glucose biosensing显示文摘A novel glucose biosensor was constructed by immobilizing the glucose oxidase(GOD) on a hydroxyapatite(HAp)/Nafion composite film modified glassy carbon electrode(GCE) and applied to the highly selective and sensitive determination of glucose.With the cooperation of HAp and Nafion,the composite film played an important role in enhancing the stability and sensitivity of the biosensor.The results demonstrate that the GOD adsorbed onto the HAp/Nafion composite film exhibits a pair of welldefined nearly reversible redox peaks and fine catalysis to the oxidation of glucose companied with the consumption of dissolved oxygen.On the basis of the decrease of the reduction current of dissolved oxygen at the applied potential of -0.80 V(vs.SCE) upon the addition of glucose,the concentration of glucose could be detected sensitively and selectively.The decreased reduction current was linear with the concentration of glucose in the range of 0.12―2.16 mM.The detection limit and sensitivity were 0.02 mM(S/N=3) and 6.75 mA·M-1,respectively.All the results demonstrate that HAp/Nafion composite film provides a novel and efficient platform for the immobilization of enzymes and realizes the direct electrochemistry.The composite materials should have potential applications in the fabrication of third-generation biosensors. | MA RongNa WANG Bin LIU Yan LI Jing ZHAO Qian WANG GuoTao JIA WenLi WANG HuaiSheng | 2009 | Science China Chemistry2009，52，11： | 3 |
| 9 | Autonomous parking control for intelligent vehicles based on a novel algorithm显示文摘Along with the increasing number of vehicles, parking space becomes narrow gradually, safety parking puts forward higher requirements on the driver's driving technology. How to safely, quickly and accurately park the vehiclo to parking space right? This paper presents an automatic parking scheme based on trajectory planning, which analyzing the mechanical model of the vehicle, establishing vehicle steering model and parking model, coming to the conclusion that it is the turning radius is independent of the vehicle speed at low speed. The Matlab simulation environment verifies the correctness and effectiveness of the proposed algorithm for parking. A class of the automatic parking problem of intelligent vehicles is solved. | Gao Hongbo Xie Guotao Zhang Xinyu Cheng Bo | 2017 | The Journal of China Universities of Posts and Telecommunications2017，24，4： | 3 |
| 10 | 基于STM32的探灭一体化智能灭火机器人设计显示文摘针对火灾的预防和处理问题,设计了一款能自动寻找火源并灭火和现场环境探测的智能移动机器人。利用超声波传感器感知周围环境并进行避障,通过火焰传感器配合PID算法实现火源的精确定位和灭火,利用摄像头完成对现场信息的采集,并搭配专用遥控器实现对机器人的控制和环境探测。实验研究表明:该机器人能够有效地实现对火源的定位和灭火动作,避障灵活准确,在消防领域具有广阔的应用前景。 | 刘征 鞠艳杰 唐雅茹 ZHONG Guotao | 2023 | 自动化与仪器仪表2023，，1： | 3 |
| 11 | ZIF-67 derived hollow Ni-Co-Se nano-polyhedrons for flexible hybrid supercapacitors with remarkable electrochemical performances显示文摘Nano-polyhedral NiSe2/CoSe2(Ni-Co-Se) with hollow architectures are synthesized by selenizing the precursors of Ni-Co bimetallic hydroxides that are directly derived from ZIF-67.The as-fabricated Ni-Co-Se electrodes exhibit high specific capacitance of 1668 F/g at 1 A/g accompanying with outstanding rate capability(about 82.8% retention of the initial capacity at 20 A/g).The corresponding Ni-Co-Se//AC all-solid-state hybrid supercapacitors are assembled by directly using the Ni-Co-Se on carbon fabric as the positive electrode,which deliver high energy density and power density(38.5 Wh/kg at 802.1 W/kg,32.0 Wh/kg at 8008.8 W/kg),excellent cyclic stability(82.3% retention after 5000 cycle) and robust mechanical flexibility(no obvious attenuation at bending to different angles).This work will provide a new and smart route for constructing transition metal selenides for supercapacitor devices. | Guangmeng Qu Xixi Zhang Guotao Xiang Yunrui Wei Jiangmei Yin Zonghua Wang Xiaoli Zhang Xijin Xu | 2020 | Chinese Chemical Letters2020，31，7： | 3 |
| 12 | Restoring After Central Nervous System Injuries:Neural Mechanisms and Translational Applications of Motor Recovery显示文摘Central nervous system(CNS)injuries,including stroke,traumatic brain injury,and spinal cord injury,are leading causes of long-term disability.It is estimated that more than half of the survivors of severe unilateral injury are unable to use the denervated limb.Previous studies have focused on neuroprotective interventions in the affected hemisphere to limit brain lesions and neurorepair measures to promote recovery.However,the ability to increase plasticity in the injured brain is restricted and difficult to improve.Therefore,over several decades,researchers have been prompted to enhance the compensation by the unaffected hemisphere.Animal experiments have revealed that regrowth of ipsilateral descending fibers from the unaffected hemisphere to denervated motor neurons plays a significant role in the restoration of motor function.In addition,several clinical treatments have been designed to restore ipsilateral motor control,including brain stimulation,nerve transfer surgery,and brain–computer interface systems.Here,we comprehensively review the neural mechanisms as well as translational applications of ipsilateral motor control upon rehabilitation after CNS injuries. | Zhengrun Gao Zhen Pang Yiming Chen Gaowei Lei Shuai Zhu Guotao Li Yundong Shen Wendong Xu | 2022 | Neuroscience Bulletin2022，38，12： | 3 |
| 13 | The first discovery of Permian conodont fauna from peri-Gondwana cool water facies in Tibet,China显示文摘The Angjie Formation and Xiala Formation,present in the Shiquanhe area of Gar County in the western part of Gangdise,Tibet,belong to the Gangdise stratigraphic subregion. Conodonts have been found in the Angjie Formation,and they permit an age determination of Early to Middle Permian for that formation. The age of the Xiala Formation could be late Middle Permian. Whether the Late Permian marine deposits are present in this area still needs to be determined,but it is possible that the lower part of the Xiala Formation overlaps partly the upper part of the Angjie Formation. More importantly,the study has brought about a finding of typical peri-Gondwana cool water facies conodonts,namely,Vjalovognathus sp. nov. x. This is the first report and brief description of a conodont fauna from peri-Gondowana cool water facies in China. It indicates that the Gangdise stratigraphic subregion can be subdivided;the western part belongs to peri-Gondwana cool water facies,and the eastern part belongs to Tethys. | ZHENG YouYe XU RongKe WANG ChengYuan MA GuoTao | 2007 | Chinese Science Bulletin2007，52，9： | 3 |
| 14 | SRSF1 plays a critical role in invariant natural killer T cell development and function显示文摘Invariant natural killer T(iNKT)cells are highly conserved innate-like T lymphocytes that originate from CD4^(+)CD8^(+)double-positive(DP)thymocytes.Here,we report that serine/arginine splicing factor 1(SRSF1)intrinsically regulates iNKT cell development by directly targeting Myb and balancing the abundance of short and long isoforms.Conditional ablation of SRSF1 in DP cells led to a substantially diminished iNKT cell pool due to defects in proliferation,survival,and TCRαrearrangement.The transition from stage 0 to stage 1 of iNKT cells was substantially blocked,and the iNKT2 subset was notably diminished in SRSF1-deficient mice.SRSF1 deficiency resulted in aberrant expression of a series of regulators that are tightly correlated with iNKT cell development and iNKT2 differentiation,including Myb,PLZF,Gata3,ICOS,and CD5.In particular,we found that SRSF1 directly binds and regulates pre-mRNA alternative splicing of Myb and that the expression of the short isoform of Myb is substantially reduced in SRSF1-deficient DP and iNKT cells.Strikingly,ectopic expression of the Myb short isoform partially rectified the defects caused by ablation of SRSF1.Furthermore,we confirmed that the SRSF1-deficient mice exhibited resistance to acute liver injury uponα-GalCer and Con A induction.Our findings thus uncovered a previously unknown role of SRSF1 as an essential post-transcriptional regulator in iNKT cell development and functional differentiation,providing new clinical insights into iNKT-correlated disease. | Jingjing Liu Menghao You Yingpeng Yao Ce Ji Zhao Wang Fang Wang Di Wang Zhihong Qi Guotao Yu Zhen Sun Wenhui Guo Juanjuan Liu Shumin Li Yipeng Jin Tianyan Zhao Hai-Hui Xue Yuanchao Xue Shuyang Yu | 2021 | Cellular & Molecular Immunology2021，18，11： | 3 |
| 15 | Application of Sol Self-Clean Bonded Al_2O_3-SiC-C Castable for Iron Runner显示文摘The properties and microstructure of sol self-clean bonded Al_ 2O_ 3-SiC-C castable in iron runner were studied, and the relation between the amount of sol self-clean binder and the properties of castable were discussed. It is believed that the addition of sol self-clean binder can improve the compressive strength, but has little effect on the bulk density and the apparent porosity, which enable the castable to be applicable in different conditions. | XU Guotao ZHANG Honglei CHEN Huasheng WANG Yue LI Huaiyuan XIONG Yafei | 2006 | China's Refractories2006，15，3： | 3 |
| 16 | Lanthanide-doped heterostructured nanocomposites toward advanced optical anti-counterfeiting and information storage显示文摘The continuously growing importance of information storage,transmission,and authentication impose many new demands and challenges for modern nano-photonic materials and information storage technologies,both in security and storage capacity.Recently,luminescent lanthanide-doped nanomaterials have drawn much attention in this field because of their photostability,multimodal/multicolor/narrowband emissions,and long luminescence lifetime.Here,we report a multimodal nanocomposite composed of lanthanide-doped upconverting nanoparticle and EuSe semiconductor,which was constructed by utilizing a cation exchange strategy.The nanocomposite can emit blue and white light under 365 and 394 nm excitation,respectively.Meanwhile,the nanocomposites show different colors under 980 nm laser excitation when the content of Tb3+ions is changed in the upconversion nanoparticles.Moreover,the time-gating technology is used to filter the upconversion emission of a long lifetime from Tb3+or Eu3+,and the possibilities for modulating the emission color of the nanocomposites are further expanded.Based on the advantage of multiple tunable luminescence,the nanocomposites are designed as optical modules to load optical information.This work enables multi-dimensional storage of information and provides new insights into the design and fabrication of next-generation storage materials. | Yao Xie Yapai Song Guotao Sun Pengfei Hu Artur Bednarkiewicz Lining Sun | 2022 | Light(Science & Applications)2022，11，6： | 3 |
| 17 | Influence of Vegetation on Runoff and Sediment in Wind-water Erosion Crisscross Region in the Upper Yellow River of China显示文摘All characteristics of vegetation,runoff and sediment from 1960 to 2010 in the Xiliu Gully Watershed,which is a representative watershed in wind-water erosion crisscross region in the upper reaches of the Yellow River of China,have been analyzed in this study.Based on the remote sensing image data,and used multi-spectral interpretation method,the characteristics of vegetation variation in the Xiliu Gully Watershed have been analyzed.And the rules of precipitation,runoff and sediment's changes have been illuminated by using mathematical statistics method.What′s more,the influence mechanism of vegetation on runoff and sediment has been discussed by using the data obtained from artificial rainfall simulation test.The results showed that the main vegetation type was given priority to low coverage,and the area of the low vegetation coverage type was reducing year by year.On the country,the area of the high vegetation coverage type was gradually increasing.In a word,vegetation conditions had got better improved since 2000 when the watershed management project started.The average annual precipitation of the river basin also got slightly increase in 2000–2010.The average annual runoff reduced by 37.5%,and the average annual sediment reduced by 73.9% in the same period.The results of artificial rainfall simulation tests showed that the improvement of vegetation coverage could increase not only soil infiltration but also vegetation evapotranspiration,and then made the rainfall-induced runoff production decrease.Vegetation root system could increases the resistance ability of soil to erosion,and vegetation aboveground part could reduce raindrop kinetic energy and splash soil erosion.Therefore,with the increase of vegetation coverage,the rainfall-induced sediment could decrease. | WANG Jinhua LI Zhanbin YAO Wenyi DONG Guotao | 2017 | Chinese Geographical Science2017，27，4： | 3 |
| 18 | China pursues a strict water resources management system显示文摘 | Qiting Zuo Runfang Jin Junxia Ma Guotao Cui | 2014 | Environmental Earth Sciences2014，，6： | 2 |
| 19 | Naphthalimide-modified near-infrared cyanine dye with a large stokes shift and its application in bioimaging显示文摘Developing the novel fluorescent dyes with a larger Stokes shift is still a challenge in the research of fluorescence probes. In this work, a naphthalimide-modified near-infrared cyanine dye with an emission at 785 nm has been synthesized for lysosome-targeting imaging. This fluorescent dye showed a large Stokes shift(up to 165 nm) and favorable lysosome-targeting property, which facilitated it to be a potential candidate for studying of lysosomal functions. The result also indicated that the probe is a promising contrast agent for in vivo imaging in mouse models. | Di Wu Yuanzhi Shen Jianhua Chen Guotao Liu Haiyan Chen Jun Yin | 2017 | Chinese Chemical Letters2017，28，10： | 2 |
| 20 | Studying the stability of the middle atmosphere (30―60km) over Wuhan by Rayleigh lidar显示文摘The stability of the middle atmosphere ranging from 30 km to 60 km over Wuhan is elementarily studied, according to the observational data obtained in about one year through the WIPM Rayleigh lidar. The stability parameter (buoyancy frequency squared), which was obtained through the temperature field, shows that the middle atmosphere over Wuhan is stable all the year round, but the sta- bility appears variable because the stability of sum- mer and winter is lower, and that of spring and au- tumn is higher. | CHANG Qihai YANG Guotao SONG Juan GONG Shunsheng | 2006 | Chinese Science Bulletin2006，51，21： | 2 |
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