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| 1 | Challenges and recent progress in thermal management with heat pipes for lithium-ion power batteries in electric vehicles显示文摘Electric vehicles(EVs)are globally undergoing rapid developments,and have great potentials to replace the traditional vehicles based on fossil fuels.Power-type lithium-ion batteries(LIBs)have been widely used for EVs,owing to high power densities,good charge/discharge stability,and long cycle life.The driving ranges and acceleration performances are gaining increasing concerns from customers,which depend highly on the power level of LIBs.With the increase in power outputs,rising heat generation significantly affects the battery performances,and in particular operation safety.Meanwhile,the cold-start performance is still an intractable problem under extreme conditions.These challenges put forward higher requirements for a dedicated battery thermal management system(BTMS).Compared to traditional BTMSs in EVs,the heat pipe-based BTMS has great application prospects owing to its compact structure,flexibility,low cost,and especially high thermal conductivity.Encompassing this topic,this review first introduces heat generation phenomena and temperature characteristics of LIBs.Multiple abuse conditions and thermal runaway issues are described afterward.Typical cooling and preheating methods for designing a BTMS are also discussed.More emphasis on this review is put on the use of various heat pipes for BTMSs to enhance the thermal performances of LIBs.For lack of wide application in actual EVs,more efforts should be made to extend the use of heat pipes for constructing an energy-efficient,cost-effective,and reliable BTMS to improve the performances and safety of EVs. | HUANG Yao TANG Yong YUAN Wei FANG GuoYun YANG Yang ZHANG XiaoQing WU YaoPeng YUAN YuHang WANG Chun LI JinGuang | 2021 | Science China(Technological Sciences)2021，64，5： | 10 |
| 2 | A multifunctional nanoparticle system combines sonodynamic therapy and chemotherapy to treat hepatocellular carcinoma显示文摘Hepatocellular 癌(HCC ) 是世界范围的最普通、致命的恶意之一。迄今为止,因为 HCC 的 insensitivity,有 HCC 的病人的幸存没改善到常规治疗。Sonodynamic 治疗(SDT ) 是在 HCC 的治疗显示出显著潜力的一条有希望的新途径。这里,我们设计了一简单,联合 SDT 和化疗到的 biocompatible,和多功能的 nanosystem 对待 HCC。这 nanosystem,叫的 HPDF nanoparticles,有 hematoporphyrin (HP ) 是有 doxorubicin (纪录影片) 的 complexed 形成恐水病的核心的核心壳在结构,表面与 Pluronic F68 是涂的形成吸水的壳。在 HCC 细胞,在有超声的照耀的联合的 HPDF nanoparticles (1.0 MHz, 1.5 W/cm 2, 30 s ) 展出有势力 cytotoxicity,源于大量反应的氧种的 synergistic 效果从 HP 和导致纪录影片的 DNA 损坏产生了。尤其是,在有超声的照耀的联合的 HPDF nanoparticles 显著地在 HCC 在 Nanog 积极的癌症干细胞(CSC ) 颠倒了药抵抗。在忍受 HCC 肿瘤的裸体老鼠,高效地在肿瘤积累并且到达了最大值的 HPDF nanoparticles 在 68 以内铺平 h,柱子静脉内的注射。HPDF nanoparticles,在有超声的照耀的联合(1.0 MHz, 3 W/cm 2, 5 min ) ,更加压制了肿瘤生长, angiogenesis,和骨胶原免职。在摘要,我们的结果证明 HPDF nanoparticles 能有效地联合 SDT 和化疗通过多重机制禁止 HCC 生长和前进在细胞并且动物模特儿。 | Yang Liu Guoyun Wan Hua Guo Yuanyuan Liu Ping Zhou Hemei wang Dan Wang Sipei Zhang Yinsong Wang Ning Zhang | 2017 | Nano Research2017，10，3： | 5 |
| 3 | Leukocyte/platelet hybrid membrane-camouflaged dendritic large pore mesoporous silica nanoparticles co-loaded with photo/chemotherapeutic agents for triple negative breast cancer combination treatment显示文摘Triple-negative breast cancer(TNBC)is an aggressive subset of breast cancer and currently lacks effective therapeutic targets.As two main phototherapeutic methods,photothermal therapy(PTT)and photodynamic therapy(PDT)show many advantages in TNBC treatment,and their combination with chemotherapy can achieve synergistic therapeutic effects.In the present study,a biomimetic nanoplatform was developed based on leukocyte/platelet hybrid membrane(LPHM)and dendritic large pore mesoporous silicon nanoparticles(DLMSNs).A near infrared(NIR)fluorescent dye IR780 and a chemotherapeutic drug doxorubicin(DOX)were co-loaded into the large pores of DLMSNs to prepare DLMSN@DOX/IR780(DDI)nanoparticles(NPs),followed by camouflage with LPHM to obtain LPHM@DDI NPs.Through the mediation of LPHM,LPHM@DDI NPs showed an excellent TNBC-targeting ability and very high PTT/PDT performances in vitro and in vivo.Upon NIR laser irradiation,LPHM@DDI NPs exhibited synergistic cytotoxicity and apoptosis-inducing activity in TNBC cells,and effectively suppressed tumor growth and recurrence in TNBC mice through tumor ablation and anti-angiogenesis.These synergistic effects were sourced from the combination of PTT/PDT and chemotherapy.Altogether,this study offers a promising biomimetic nanoplatform for efficient co-loading and targeted delivery of photo/chemotherapeutic agents for TNBC combination treatment. | Tao Zhang Hui Liu Ling Li Zhaoyang Guo Jia Song Xiaoying Yang Guoyun Wan Rongshan Li Yinsong Wang | 2021 | Bioactive Materials2021，6，11： | 4 |
| 4 | Topology Optimization with Aperiodic Load Fatigue Constraints Based on Bidirectional Evolutionary Structural Optimization显示文摘Because of descriptive nonlinearity and computational inefficiency,topology optimization with fatigue life under aperiodic loads has developed slowly.A fatigue constraint topology optimization method based on bidirectional evolutionary structural optimization(BESO)under an aperiodic load is proposed in this paper.In viewof the severe nonlinearity of fatigue damagewith respect to design variables,effective stress cycles are extracted through transient dynamic analysis.Based on the Miner cumulative damage theory and life requirements,a fatigue constraint is first quantified and then transformed into a stress problem.Then,a normalized termination criterion is proposed by approximatemaximum stress measured by global stress using a P-normaggregation function.Finally,optimization examples show that the proposed algorithm can not only meet the requirements of fatigue life but also obtain a reasonable configuration. | Yongxin Li Guoyun Zhou Tao Chang Liming Yang Fenghe Wu | 2022 | Computer Modeling in Engineering & Sciences2022，，1： | 1 |
| 5 | A polymeric prodrug of cisplatin based on pullulan for the targeted therapy against hepatocellular carcinoma显示文摘 | Yan Wang Yuanyuan Liu Yang Liu Wen Zhou Hemei Wang Guoyun Wan Duxin Sun Ning Zhang Yinsong Wang | 2015 | International Journal of Pharmaceutics . 2015 (1-2)2015，，： | 1 |
| 6 | The Jidong Eye Cohort Study:objectives,design,and baseline characteristics显示文摘Background:To describe the objective,design and baseline characteristics of the Jidong Eye Cohort Study(JECS),a community-based cohort in China based on etiology,imaging and biomarkers.The JECS will clarify the pathogenesis of visual impairment and status of ocular indicators in the occurrence and progression of cardiocerebrovascular and neurological diseases.Methods:Between August 2019 and January 2020,the JECS recruited consecutive participants aged 18 years and older from the Jidong communities in China.The demographic and clinical characteristics were collected by trained site personnel via face-to-face interviews.The relevant biological samples were also collected.The participants underwent comprehensive ophthalmic examination,such as retinal photography and optical coherence tomography(OCT)angiography.The following outcomes were measured annually:ocular vascular abnormality,optic nerve degeneration,cardiovascular diseases(CVD)and neurological diseases.The study will be performed until 2024.Results:Among 3377 participants,the average age was 45.0±12.5 years and 1809(53.6%)were women.Hypertension occurred in 825 individuals(25.0%),diabetes in 258(7.7%),hyperglycemia in 474(14.2%),and a CVD history in 100(3.0%).The mean best-corrected visual acuity was 0.1 logMAR in the recruited subjects.The average OCT signal index was 8.2±1.2.Additionally,the mean vessel densities for the entire measured area were 46.4%and 50.8%for the superficial and deep vascular complex,respectively.Mean area and perimeter of foveal avascular zone was 0.3 mm2 and 2.3 mm.Conclusions:The JECS is a large community-based prospective cohort in North China.Rich data collected from this study will provide the opportunity to identify risk factors,imaging,and biomarkers of visual impairment(either ocular vascular anomalies or optic nerve degeneration)and to evaluate their associations with CVD and neurological diseases. | Kai Yang Lele Cui Guoyun Zhang Xianwei Wang Xiaoxuan Zhu Yunfan Xiao Binbin Su Daiyu Song Xinyao Zhang Yang Zheng Fan Lu Jia Qu Ming Li | 2020 | Eye and Vision2020，7，1： | 0 |
| 7 | Growth of Tellurium Nanobelts on h-BN for p-type Transistors with Ultrahigh Hole Mobility显示文摘The lack of stable p-type van der Waals(vdW)semiconductors with high hole mobility severely impedes the step of low-dimensional materials entering the industrial circle.Although p-type black phosphorus(bP)and tellurium(Te)have shown promising hole mobilities,the instability under ambient conditions of bP and relatively low hole mobility of Te remain as daunting issues.Here we report the growth of high-quality Te nanobelts on atomically flat hexagonal boron nitride(h-BN)for high-performance p-type field-effect transistors(FETs).Importantly,the Te-based FET exhibits an ultrahigh hole mobility up to 1370 cm^(2) V^(−1) s^(−1) at room temperature,that may lay the foundation for the future high-performance p-type 2D FET and metal-oxide-semiconductor(p-MOS)inverter.The vdW h-BN dielectric substrate not only provides an ultra-flat surface without dangling bonds for growth of high-quality Te nanobelts,but also reduces the scattering centers at the interface between the channel material and the dielectric layer,thus resulting in the ultrahigh hole mobility. | Peng Yang Jiajia Zha Guoyun Gao Long Zheng Haoxin Huang Yunpeng Xia Songcen Xu Tengfei Xiong Zhuomin Zhang Zhengbao Yang Ye Chen Dong-Keun Ki Juin J.Liou Wugang Liao Chaoliang Tan | 2022 | Nano-Micro Letters2022，14，7： | 0 |
| 8 | A chromosome-level genome assembly for Erianthus fulvus provides insights into its biofuel potential and facilitates breeding for improvement of sugarcane显示文摘Erianthus produces substantial biomass,exhibits a good Brix value,and shows wide environmental adaptability,making it a potential biofuel plant.In contrast to closely related sorghum and sugarcane,Erianthus can grow in degraded soils,thus releasing pressure on agricultural lands used for biofuel production.However,the lack of genomic resources for Erianthus hinders its genetic improvement,thus limiting its potential for biofuel production.In the present study,we generated a chromosome-scale reference genome for Erianthus fulvus Nees.The genome size estimated by flow cytometry was 937 Mb,and the assembled genome size was 902 Mb,covering 96.26%of the estimated genome size.A total of 35065 proteincoding genes were predicted,and 67.89%of the genome was found to be repetitive.A recent wholegenome duplication occurred approximately 74.10 million years ago in the E.fulvus genome.Phylogenetic analysis showed that E.fulvus is evolutionarily closer to S.spontaneum and diverged after S.bicolor.Three of the 10 chromosomes of E.fulvus formed through rearrangements of ancestral chromosomes.Phylogenetic reconstruction of the Saccharum complex revealed a polyphyletic origin of the complex and a sister relationship of E.fulvus with Saccharum sp.,excluding S.arundinaceum.On the basis of the four amino acid residues that provide substrate specificity,the E.fulvus SWEET proteins were classified as monoand disaccharide sugar transporters.Ortho-QTL genes identified for 10 biofuel-related traits may aid in the rapid screening of E.fulvus populations to enhance breeding programs for improved biofuel production.The results of this study provide valuable insights for breeding programs aimed at improving biofuel production in E.fulvus and enhancing sugarcane introgression programs. | Ling Kui Aasim Majeed Xianhong Wang Zijiang Yang Jian Chen Lilian He Yining Di Xuzhen Li Zhenfeng Qian Yinming Jiao Guoyun Wang Lufeng Liu Rong Xu Shujie Gu Qinghui Yang Shuying Chen Hongbo Lou Yu Meng Linyan Xie Fu Xu Qingqing Shen Amit Singh Karl Gruber Yunbing Pan Tingting Hao Yang Dong Fusheng Li | 2023 | Plant Communications2023，4，4： | 0 |
| 9 | Study on Practical Mature Age of Individual Pinus thunbergii×P. densiflora显示文摘This study was conducted on the analytic tree and got the fitting empirical equation of tree growth, in which the tree increment was used as the variable and time as the independent variable. The arithmetical operation to the function gave the mature age of tree growth, and the practical mature age of Pinus thunbergii×P. densiflora was 41 a. In addition, the application as well as the research direction and matters needing attention were proposed. | Zhimin CHEN Guoyun YANG Fuming QIAN Xicui WANG Kejia YANG Decui SHU | 2019 | Agricultural Biotechnology2019，8，6： | 0 |
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