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| 1 | A multifunctional nanoparticle system combines sonodynamic therapy and chemotherapy to treat hepatocellular carcinoma显示文摘Hepatocellular 癌(HCC ) 是世界范围的最普通、致命的恶意之一。迄今为止,因为 HCC 的 insensitivity,有 HCC 的病人的幸存没改善到常规治疗。Sonodynamic 治疗(SDT ) 是在 HCC 的治疗显示出显著潜力的一条有希望的新途径。这里,我们设计了一简单,联合 SDT 和化疗到的 biocompatible,和多功能的 nanosystem 对待 HCC。这 nanosystem,叫的 HPDF nanoparticles,有 hematoporphyrin (HP ) 是有 doxorubicin (纪录影片) 的 complexed 形成恐水病的核心的核心壳在结构,表面与 Pluronic F68 是涂的形成吸水的壳。在 HCC 细胞,在有超声的照耀的联合的 HPDF nanoparticles (1.0 MHz, 1.5 W/cm 2, 30 s ) 展出有势力 cytotoxicity,源于大量反应的氧种的 synergistic 效果从 HP 和导致纪录影片的 DNA 损坏产生了。尤其是,在有超声的照耀的联合的 HPDF nanoparticles 显著地在 HCC 在 Nanog 积极的癌症干细胞(CSC ) 颠倒了药抵抗。在忍受 HCC 肿瘤的裸体老鼠,高效地在肿瘤积累并且到达了最大值的 HPDF nanoparticles 在 68 以内铺平 h,柱子静脉内的注射。HPDF nanoparticles,在有超声的照耀的联合(1.0 MHz, 3 W/cm 2, 5 min ) ,更加压制了肿瘤生长, angiogenesis,和骨胶原免职。在摘要,我们的结果证明 HPDF nanoparticles 能有效地联合 SDT 和化疗通过多重机制禁止 HCC 生长和前进在细胞并且动物模特儿。 | Yang Liu Guoyun Wan Hua Guo Yuanyuan Liu Ping Zhou Hemei wang Dan Wang Sipei Zhang Yinsong Wang Ning Zhang | 2017 | Nano Research2017，10，3： | 5 |
| 2 | Private Car Travel Characteristics and Influencing Factors in Chinese Cities——A Case Study of Guangzhou in Guangdong,China显示文摘Taking Guangzhou as a case,this paper adopted a questionnaire survey to gather first-hand data and analyzed the characteristics and influencing factors of private car travel in Chinese cities.As the research indicated,trip purposes of private car travel are mainly commute and business affairs with a more flexible trip in the urban core area.And trip intensities are concentrated in a certain extent,with trip frequency being lower in the urban core area than the peripheral area.In addition,the trip time has two significant peaks occurring in the morning and afternoon,and one trough in the midday.And trip spatial distribution is mainly within commute with both residence and employment in urban area and inward commute with residence in suburban area while employment in urban area.Both kinds of commutes direct to the urban area.The study also shows that the characteristics of private car travel are principally influenced by two aspects:travelers' attributes and urban characteristics.The main travelers' social and economic attributes influenced it include the gender,education attainment,age,driving experience and per capita monthly household income.The urban characteristics influenced it mainly cover the land use pattern,public traffic facilities and spatial attributes of residential environment. | CAO Xiaoshu CHEN Hemei LI Linna ZHEN Feng | 2009 | Chinese Geographical Science2009，19，4： | 5 |
| 3 | Operative fixation ofchestwall fractures:an underused procedure显示文摘 | Richardson JD Franklin GA Hemey S | 2007 | Am Surg2007，73，6： | 1 |
| 4 | Partitioning of Amino Acids by Aqueous Two‐Phase Systems Combined with Temperature‐Induced Phase Formation显示文摘 | MianLi Zi‐QiangZhu Le‐HeMei | 2008 | Biotechnol Progress2008，，1： | 1 |
| 5 | Perfluoroisobutylene-induced acute lung injury and mortality are heralded by neutrophil se-questration and accumulation 显示文摘 | Hemei Wang Rigao Ding Jinxiu Ruan | 2001 | J Occu Health2001，43，6： | 1 |
| 6 | Injury of cell tightjunctions and changes of actin level in acute lung injury caused by theperfluoroisobutylene exposure and the role of myosin light chain kinase显示文摘 | MENG Ge ZHAO Jian WANG Hemei | 2011 | J Occap Health2011，53，4： | 1 |
| 7 | Cell injuries of theblood-air barrier in acute lung injury caused by perfluoroisobutylene ex-posure 显示文摘 | MENG Ge ZHAO Jian WANG Hemei | 2010 | J Occup Health2010，52，1： | 1 |
| 8 | Percutaneous bone marrow grafting of delayed union and nonunion in cancer pa-tients显示文摘 | HeMey JH Zimmerman PA McDonnell JM | 1990 | Clin Orthop Relat Res1990，256，： | 1 |
| 9 | A polymeric prodrug of cisplatin based on pullulan for the targeted therapy against hepatocellular carcinoma显示文摘 | Yan Wang Yuanyuan Liu Yang Liu Wen Zhou Hemei Wang Guoyun Wan Duxin Sun Ning Zhang Yinsong Wang | 2015 | International Journal of Pharmaceutics . 2015 (1-2)2015，，： | 1 |
| 10 | EXPLOITING THE LANGUAGE LAB:A WAY TO MAKE LAB - BASED AUDIOVISUAL COURSE COMMUNICATIVE显示文摘Introduction With the rapid development of computer technology, computer assisted instruction (CAI) has found a wide application in English teaching and Learning. The United States started the study of CAI systems at the beginning of the 1960s, whereas China started in the mid 1980s. | Jiang Hemei associate professor, Department of Foreign Language, Shanghai commercial Polytechnic | 2000 | 上海商业职业技术学院学报2000，1，1： | 0 |
| 11 | Expansive Soil Stabilization by Bagasse Ash in Partial Replacement of Cement显示文摘This study examined the effects of using bagasse ash in replacement of ordinary Portland cement(OPC)in the treatment of expansive soils.The study concentrated on the compaction characteristics,volume change,compressive strength,splitting tensile strength,microstructure,California bearing ratio(CBR)value,and shear wave velocity of expansive soils treated with cement.Different bagasse ash replacement ratios were used to create soil samples.At varying curing times of 7,14,and 28 days,standard compaction tests,unconfined compressive strength tests,CBR tests,Brazilian split tensile testing,and bender element(BE)tests were carried out.According to X-ray diffraction(XRD)investigations,quartz and crystobalite make up the majority of the minerals in bagasse ash.Bagasse ash contains a variety of grain sizes,including numerous fiber-shaped particles,according to a scanning electronic microscope(SEM)test.For all of the treated specimens with various replacement ratios,the overall additive content has not changed.The results of the Brazilian split tensile tests demonstrate improved tensile strength for all specimens with various replacement proportions.A lower maximum dry density and a greater optimal water content would result from the substitution of bagasse ash.When the replacement ratio is not more than 20%,the CBR values of the parts replaced specimens are even higher than the cement treatments.The results of BE testing on the treated soils show that there is significant stiffness anisotropy but that it steadily diminishes with curing time and replacement ratio.According to the study,bagasse ash is a useful mineral additive,and the best replacement ratio(CBA20)is 20%. | Waleed Awadalseed Honghua Zhao Hemei Sun Ming Huang Cong Liu | 2023 | Journal of Renewable Materials2023，11，4： | 0 |
| 12 | EuP能耗规定新出炉显示文摘EUP指令的实施对绝大部分设计人员而言将是一次设计思想的革命。EuP指令并不是针对产品要求的指令,而只是一个框架指令。欧盟按照这一指令中的相关规定,制定进一步的有关产品要求的指令,称作'实施措施(implementing measures)'。由于目前没有新的实施措施制定出来,大部分企业都在进行观望,不知如何应对。 | 徐俊毅(Hemey Xu) 郭伟祥 | 2008 | 电子与电脑2008，8，7： | 0 |
| 13 | Silencing of long non-coding RNA CCHE1 inhibits the ovarian cancer SKOV3 cell invasion and migration and inactivates the p38-MAPK signaling pathway显示文摘Ovarian cancer(OC)is a major cause of cancer-related deaths among gynaecologicalmalignancies.Emerging studies suggest that the long non-coding RNA(lncRNA)may be the potential biomarker for the diagnosis and prognosis of the cancer.The current study was carried out to investigate the role of lncRNA CCHE1 silencing in OC cell invasion and migration.Expression of lncRNA CCHE1 in normal ovarian cell Hose and OC cell lines HO 8910,A2780 and SKOV3 was detected.LncRNA were transfected with siRNA,and then the proliferation of cells was detected by using MTT assay.Cell invasion and migration was measured by using Transwell assay and scratch test,respectively.The protein levels of E-cadherin,N-cadherin,ERK,p38-MAPK and the phosphorylation of ERK and p38-MAPK in cells after siRNA transfection were detected by using Western blot analysis.Consequently,lncRNA CCHE1 expression was highly expressed in OC cell lines,especially in SKOV3 cells.siRNA1,siRNA2 and siRNA3 all decreased.lncRNA CCHE1 expression in SKOV3 cells and siRNA2 showed the best silencing efficacy.Silencing of lncRNA CCHE1 decreased proliferation,invasion and migration,and reduced the protein levels of N-cadherin,ERK,p38-MAPK and the phosphorylation of ERK and p38-MAPK,while reducing the protein level of E-cadherin in SKOV3 cells.Collectively,our study proved that the silencing of lncRNA CCHE1 could inhibit SKOV3 cell invasion and migration via inactivating the p38-MAPK signaling pathway. | HONGWEI CHEN XUAN SONG HEMEI LI | 2020 | BIOCELL2020，44，3： | 0 |
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