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| 1 | New field of cryptography: DNA cryptography显示文摘DNA cryptography is a new born cryp- tographic field emerged with the research of DNA computing, in which DNA is used as information car- rier and the modern biological technology is used as implementation tool. The vast parallelism and ex- traordinary information density inherent in DNA molecules are explored for cryptographic purposes such as encryption, authentication, signature, and so on. In this paper, we briefly introduce the biological background of DNA cryptography and the principle of DNA computing, summarize the progress of DNA cryptographic research and several key problems, discuss the trend of DNA cryptography, and compare the status, security and application fields of DNA cryptography with those of traditional cryptography and quantum cryptography. It is pointed out that all the three kinds of cryptography have their own ad- vantages and disadvantages and complement each other in future practical application. The current main difficulties of DNA cryptography are the absence of effective secure theory and simple realizable method. The main goal of the research of DNA cryptography is exploring characteristics of DNA molecule and reac- tion, establishing corresponding theories, discovering possible development directions, searching for sim- ple methods of realizing DNA cryptography, and lay- ing the basis for future development. | XIAO Guozhen LU Mingxin QIN Lei LAI Xuejia | 2006 | Chinese Science Bulletin2006，51，12： | 16 |
| 2 | Transformation of human amniotic epithelial cells into neuron-like cells in the microenvironment of traumatic brain injury in vivo and in vitro显示文摘Survival and differentiation of transplanted cells is closely related to the local microenvironment.The present study cultured human amniotic epithelial cells(HAECs) in a simulated microenvironment in vitro comprising RPMI 1640 culture medium and the solution extracted from injured brain tissues.Some HAECs were round,triangular in form or irregularly shaped,with extended neuron-like processes;some of the processes were interconnected,representing neuron-like morphology and some HAECs were microtubule-associated protein 2-positive.HAECs survived for at least 4 weeks following transplantation into the center and edges of the trauma focus with traumatic brain injury,and were microtubule-associated protein 2-positive.Moreover,the motor function of rat hind limbs was significantly improved. | Yi Lu Guozhen Hui Zhiyuan Wu Tianjin Liu Xunhe Ji Lihe Guo | 2011 | Neural Regeneration Research2011，6，10： | 10 |
| 3 | Polynomials,Higher Order Sobolev Extension Theorems and Interpolation Inequalities on Weighted Folland-Stein Spaces on Stratified Groups | Guozhen Lu Department of Mathematics,Wayne State University,Detroit,MI 48202,USA | 2000 | Acta Mathematica Sinica,English Series2000，16，3： | 9 |
| 4 | Incidence and prevalence of moyamoya disease in urban China: a nationwide retrospective cohort study显示文摘Background and objective Moyamoya disease(MMD)is an increasingly recognised cause of stroke,mainly described in East Asia.China is the largest nation in Asia,but few studies reported the epidemiology of MMD,especially at a national level.We aimed to estimate the incidence and prevalence of MMD in China.Methods We performed a population-based study using data from the national databases of Urban Basic Medical Insurance between 2013 and 2016,covering approximately 0.50 billion individuals.MMD cases were identified by diagnostic code(International Classification of Diseases,10th Revision I67.5)or related diagnostic text.Results A total of 1987 MMD patients(mean age 44.45±14.30 years,female-to male ratio 1.12)were identified,representing a national crude incidence of 0.59(95%CI:0.49 to 0.68)and a prevalence of 1.01(95%CI:0.81 to 1.21)per 100000 person-years in 2016.Rates were higher in females than in males for the incidence(0.66 vs 0.52)and prevalence(1.05 vs 0.90).And the age-specific rates showed a bimodal distribution,with the highest peak in middle-aged group and the second peak in child group.Conclusions Our results confirm that MMD is relatively common in East Asians,but the rates in China were lower than those in other East Asian countries such as Japan and Korea.The unique epidemiological features,including a relatively weak female predominance and a shift in the highest peak of incidence from children to adults,revealed new sight into MMD.Further research is expected to explore the potential pathogenesis of MMD. | Yixin Sun Guoyu Zhou Jingnan Feng Lu Chen Guozhen Liu Jinxi Wang Qingliang Wang Junyou Yu Xiwang Yang Zheng Yang Pei Gao Shengfeng Wang Siyan Zhan | 2021 | Stroke & Vascular Neurology2021，6，4： | 4 |
| 5 | Label-free and real-time detection of antigen-antibody interactions by Oblique-incidence Reflectivity Difference(OIRD) method显示文摘We label-free and real-time detected three interaction processes of antigen-antibodies,Human Immunoglobulin G(IgG),Rabbit IgG,and Mouse IgG as the targets,and Goat Anti-human IgG,Goat Anti-rabbit IgG,and Goat Anti-mouse IgG as the probe,by the Oblique-incidence Reflectivity Difference(OIRD) method.The interaction dynamic curves of the OIRD signal,corresponding to the interaction processes of antigen-antibodies,are generated.The reaction times from beginning to equilibrium state are about 1800,900,and 1200 s for Human IgG,Rabbit IgG,and Mouse IgG,respectively.The experimental results demonstrate that the OIRD method not only can distinguish biomolecular interactions,but also can be used in real-time detection of interactions and dynamic processes of biomolecules. | HE LiPing SUN Yue DAI Jun WANG JingYi LU HuiBin WANG ShuFang JIN KuiJuan ZHOU YueLiang YANG GuoZhen | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，9： | 4 |
| 6 | Human amniotic epithelial cells express specific markers of nerve cells and migrate along the nerve fibers in the corpus callosum显示文摘Human amniotic epithelial cells were isolated from a piece of fresh amnion. Using immunocytochemical methods, we investigated the expression of neuronal phenotypes (microtubule-associated protein-2, glial fibrillary acidic protein and nestin) in human amniotic epithelial cells. The conditioned medium of human amniotic epithelial cells promoted the growth and proliferation of rat glial cells cultured in vitro, and this effect was dose-dependent. Human amniotic epithelial cells were further transplanted into the corpus striatum of healthy adult rats and the grafted cells could integrate with the host and migrate 1-2 mm along the nerve fibers in corpus callosum. Our experimental findings indicate that human amniotic epithelial cells may be a new kind of seed cells for use in neurograft. | Zhiyuan Wu Guozhen Hui Yi Lu Tianjin Liu Qin Huang Lihe Guo | 2012 | Neural Regeneration Research2012，7，1： | 3 |
| 7 | A study on surface symmetry and interfacial enhancement of SrTiO_3 by second harmonic generation显示文摘The symmetry of the surfaces of SrTiO3and slightly Nb-doped SrTiO3crystals was investigated by the optical reflected second harmonic generation technique.The good agreement between experimental and theoretical results of the second harmonic intensity dependence on the azimuth angle indicates that the SrTiO3(001)surface is with 4mm symmetry and the Nb-doped SrTiO3(111)surface with 3m symmetry.The measurements of the polarization dependent second harmonic intensity confirm that conclusion.The enhancement of the surface polarization in the structure of SrTiO3capped La0.9Sr0.1MnO3films compared with that in the La0.9Sr0.1MnO3films has been obtained. | ZHAO RuiQiang JIN KuiJuan GUO HaiZhong LU HuiBin YANG GuoZhen | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，12： | 3 |
| 8 | Effect of electroacpuncture of Neiguan(PC 6)and Tianquan(PC 2)on skin temperature,blood perfusion,and adrenoceptor response in rats with acute myocardial ischemia显示文摘OBJECTIVE: To investigate the effect of electroacupuncture(EA) of acupoints Neiguan(PC 6) and Tianquan(PC 2) on the skin temperature, blood perfusion, and alpha1-and beta2-adrenoreceptor(α1-AR and β2-AR) protein and m RNA level in rats with acute myocardial ischemia.METHODS: Thirty male adult Wistar rats [(230 ±20) g] were randomly assigned into five groups(n = 6 each): a control group, sham operation group, model group, model group treated with EA at low frequency(L-EA, 2 Hz, 1 m A) and model group treated with EA at high frequency(H-EA, 100 Hz, 1 m A). The rat model was prepared by ligating the left anterior descending coronary artery. Electroacupuncture was performed at the left Neiguan(PC 6) for 20 min daily for 3 d. After the 3 rd time of the treatment, measurements of skin blood perfusion and temperature in Neiguan(PC 6) and Tianquan(PC 2) in all groups were made by laser speckle contrast imaging and infrared thermal image instrument. Real-time PCR and ELISA were used to measure m RNA level and protein level of α1-AR andβ2-AR in the skin tissues of Neiguan(PC 6) and Tianquan(PC 2), respectively. Serum levels of c Tn T and electrocardiogram were used to identify the state of myocardium.RESULTS: In the group receiving electroacupunture at Neiguan(PC 6), compared with control group,the skin temperature, blood perfusion, and β2-AR m RNA and protein level of model group significantly decreased(P < 0.05), α1-AR m RNA and protein level of model group significantly increased(P < 0.05);compared with model group, the skin temperature,blood perfusion, and β2-AR m RNA and protein level of L-EA significantly increased(P < 0.05), α1-AR m RNA and protein level of L-EA and H-EA significantly decreased(P < 0.05). The same trend has taken place in the former four groups of the Tianquan(PC 2).CONCLUSION: Low-or high-frequency electroacupuncture can improve the skin temperature and blood perfusion which may be induced by decreasingthelevelofα1-ARandincreasingthelevelofβ2-AR of the Neiguan(PC 6) and Tianquan(PC 2) in the rat with acute myocaidial ischemia. | Wang Dan Ji Bo Zhao Guozhen Yan Mingna Bai Hongxin Sun Xiaomin Dai Jian Lu Yawen Liu Yitian You Min Wu Jiaojuan Ge Yunpeng Su Hang Cheng Kai | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 3 |
| 9 | Label-free detection repeatability of protein microarrays by oblique-incidence reflectivity difference method显示文摘We examine the repeatabilities of oblique-incidence reflectivity difference(OIRD) method for label-free detecting biological molecular interaction using protein microarrays.The experimental results show that the repeatabilities are the same in a given microarray or microarray-microarray and are consistent,indicating that OIRD is a promising label-free detection technique for biological microarrays. | DAI Jun LI Lin WANG JingYi HE LiPing LU HuaBin RUAN KangCheng JIN KuiJuan YANG GuoZhen | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，12： | 3 |
| 10 | Oxygen vacancy induced magnetism in BaTiO_(3-δ) and Nb:BaTiO_(3-δ) thin films显示文摘The unusual magnetic properties are observed in oxygen deficient BaTiO3-δ(BTO) and Nb:BaTiO3-δ(BNTO) thin films fabricated on SrTiO3 substrates by laser molecular beam epitaxy.The distinct magnetic hysteresis loops are observed in the oxygen deficient BTO and BNTO thin films in a temperature range of 5 to 300 K,whereas the diamagnetism is observed in both BTO and BNTO annealed at 1 atm of oxygen.The dopant Nb only enhances the magnetization in BNTO thin films,but has little effect on the coercivity.The magnetism of BTO and BNTO films is proposed to be the oxygen vacancies by origin. | YANG Fang,JIN KuiJuan,LU HuiBin,HE Meng,WANG Cong,WEN Juan & YANG GuoZhen Beijing National Laboratory for Condensed Matter Physics,Institute of Physics,Chinese Academy of Sciences,Beijing 100190,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，5： | 3 |
| 11 | EMBEDDING THEOREMS ON CAMPANATO-MORREY SPACES FOR VECTOR FIELDS OF HoRMANDER TYPE显示文摘This paper deals with embedding theorems on Campanato-Marrey spaces formed by degenerate vector fields, which include Honnander and Grushin type of vector fields. These embedding theorems are somewhat different from the known Poincare estimates. The main ingredients of the proofs rely on the fractional maximal functions. These results evidently have applications to the regularity of subelliptic PDE. | Guozhen Lu (Wright State University, USA) | 1998 | Analysis in Theory and Applications1998，14，1： | 3 |
| 12 | Towards a Dynamic Controller Scheduling-Timing Problem in Software-Defined Networking显示文摘Controller vulnerabilities allow malicious actors to disrupt or hijack the Software-Defined Networking. Traditionally, it is static mappings between the control plane and data plane. Adversaries have plenty of time to exploit the controller's vulnerabilities and launch attacks wisely. We tend to believe that dynamically altering such static mappings is a promising approach to alleviate this issue, since a moving target is difficult to be compromised even by skilled adversaries. It is critical to determine the right time to conduct scheduling and to balance the overhead afforded and the security levels guaranteed. Little previous work has been done to investigate the economical time in dynamic-scheduling controllers. In this paper, we take the first step to both theoretically and experimentally study the scheduling-timing problem in dynamic control plane. We model this problem as a renewal reward process and propose an optimal algorithm in deciding the right time to schedule with the objective of minimizing the long-term loss rate. In our experiments, simulations based on real network attack datasets are conducted and we demonstrate that our proposed algorithm outperforms given scheduling schemes. | Zhenping Lu Fucai Chen Guozhen Cheng Chao Qi Jianjian Ai | 2017 | China Communications2017，14，10： | 2 |
| 13 | Some equivalent definitions of high order Sobolev spaces on stratified groups and generalizations to metric spaces显示文摘 | Yongping Liu Guozhen Lu Richard L. Wheeden | 2002 | Mathematische Annalen2002，，1： | 1 |
| 14 | Some equivalent definitions of high order Sobolev spaces on stratified groups and generalizations to metric spaces显示文摘 | Yongping Liu Guozhen Lu Richard L. Wheeden | 2002 | Mathematische Annalen2002，，1： | 1 |
| 15 | A critical Trudinger-Moser inequality involving a degenerate potential and nonlinear Schrodinger equations显示文摘The classical critical Trudinger-Moser inequality in R^(2)under the constraint∫_(R_(2))(|▽u|^(2)+|u|^(2))dx≤1 was established through the technique of blow-up analysis or the rearrangement-free argument:for anyτ>0,it holds that sup u∈H^(1)(r^(2)fR^(2)(τ|U|^(2)+|▽u|^(2)dx≤1∫_(R^(2)(E^4π|u|^(2)-1)dx≤C(τ)<+∞)))and 4πis sharp.However,if we consider the less restrictive constraint∫_(R_(2))(|▽u|^(2)+|u|^(2))dx≤1,where V(x)is nonnegative and vanishes on an open set in R^(2),it is unknown whether the sharp constant of the Trudinger-Moser inequality is still 4π.The loss of a positive lower bound of the potential V(x)makes this problem become fairly nontrivial.The main purpose of this paper is twofold.We will first establish the Trudinger-Moser inequality sup u∈H^(1)(r^(2)fR^(2)(τ|U|^(2)+|▽u|^(2)dx≤1∫_(R^(2)(E^4π|u|^(2)-1)dx≤C(τ)<+∞)))when V is nonnegative and vanishes on an open set in R^(2).As an application,we also prove the existence of ground state solutions to the following Sciridinger equations with critical exponeitial growth:-Δu+V(x)u=f u)in R^(2),(0.1)where V(x)≥0 and vanishes on an open set of R^(2)and f has critical exponential growth.Having a positive constant lower bound for the potential V(x)(e.g.,the Rabinowitz type potential)has been the standard assumption when one deals with the existence of solutions to the above Schrodinger equations when the nonlinear term has the exponential growth.Our existence result seems to be the first one without this standard assumption. | Lu Chen Guozhen Lu Maochun Zhu | 2021 | Science China Mathematics2021，64，7： | 1 |
| 16 | Liouville-type theorems and decay estimates for solutions to higherorder elliptic equations显示文摘 | Lu Guozhen Wang Peiyong Zhu Jiuyi | 2012 | Ann I H Poincarfi-AN2012，29，5： | 1 |
| 17 | Flexible Energy‐Storage Devices: Design Consideration and Recent Progress显示文摘 | Xianfu Wang Xihong Lu Bin Liu Di Chen Yexiang Tong Guozhen Shen | 2014 | Adv. Mater2014，，28： | 1 |
| 18 | Interfacial-Strain-Induced Structural and Polarization Evolutions in Epitaxial Multiferroic BiFeO_3(001) Thin Films显示文摘Varying the film thickness is a precise route to tune the interfacial strain to manipulate the properties of the multiferroic materials.Here,to explore the effects of the interfacial strain on the properties of the multiferroic BiFeO_3films,we investigated thickness-dependent structural and polarization evolutions of the BiFeO_3 films.The epitaxial growth with an atomic stacking sequence of BiO/TiO_2 at the interface was confirmed by scanning transmission electron microscopy.Combining X-ray diffraction experiments and first-principles calculations,a thickness-dependent structural evolution was observed from a fully strained tetragonality to a partially relaxed one without any structural phase transition or rotated twins.The tetragonality(c/a) of the BiFeO_3 films increases as the film thickness decreases,while the polarization is in contrast with this trend,and the size effect including the depolarization field plays a crucial role in this contradiction in thinner films.These findings offer an alternative strategy to manipulate structural and polarization properties by tuning the interfacial strain in epitaxial multiferroic thin films. | 郭海中 Ruiqiang Zhao Kui-juan Jin Lin Gu Dongdong Xiao Zhenzhong Yang Xiaolong Li Le Wang Xu He Junxing Gu Qian Wan Can Wang Huibin Lu Chen Ge Meng He Guozhen Yang | 2015 | 功能材料信息2015，12，3： | 1 |
| 19 | Muhilinear Calder6n-Zygmund operators with kernels of Dini's type and applications 显示文摘 | LU Guozhen ZHANG Pu | 2014 | Nonlinear Analysis:Theory Methods and Applications2014，107，1： | 1 |
| 20 | Dual-Energy Computed Tomography Imaging of Thyroid Nodule Specimens: Comparison With Pathologic Findings显示文摘 | Ming Li Xiangpeng Zheng Jianying Li Yanli Yang Chen Lu Hua Xu Bo Yu Li Xiao Guozhen Zhang Yanqing Hua | 2012 | Investigative Radiology2012，，1： | 1 |
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