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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020,28,3: | 516 |
| 2 | SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway显示文摘当严重急性呼吸症候群日冕病毒(SARS-CoV ) 开始被认为与质膜通过直接熔化进入房间时,更最近的证据建议那个病毒条目可以也包含 endocytosis。我们发现了那 SARS-CoV 进入房间经由 pH 依赖并且受体依赖者 endocytosis。有任何一个 SARS-CoV 尖铁蛋白质或忍受尖铁的假病毒的房间的治疗导致了变换血管收缩素的酶的 translocation 2 (ACE2 ) , SARS-CoV 的功能的受体,从房间表面到内涵体。另外,忍受尖铁的假病毒和 1 在内涵体被发现到 colocalize 的早内涵体抗原。用象 caveolin-1 colocalization 学习一样的特定的 endocytic 小径禁止者和主导否定的 Eps15 的进一步的分析建议那个病毒条目被 clathrin 独立、 caveolae 独立的机制调停。而且,在质膜的微域,它被显示出到为许多生理的发信号小径作为平台扮演的充满胆固醇、 sphingolipid 富有的类脂化合物木排,被显示涉及病毒入口。SARS-CoV 的 Endocytic 入口可以扩展这里的 SARS-CoV 感染,和我们的调查结果的细胞的范围贡献 SARS-CoV 致病的理解,为抗病毒的药研究提供新信息。 | Wang,H Yang,P Liu,K Guo,F Zhang,Y Zhang,G Jiang,C | 2008 | Cell Research2008,18,2: | 50 |
| 3 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016,24,11: | 4 |
| 4 | Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats显示文摘 | Yang Y Liu X Long Y Wang F Ding JH Liu SY Sun YH Yao HH Wang H Wu J Hu G | 2006 | 中国生物学文摘2006,20,10: | 4 |
| 5 | UNIPIC code for simulations of high power microwave devices显示文摘 | WANG J G ZHANG D H LIU C L | | 0,,03: | 3 |
| 6 | Magnetically recoverable nanoparticles:highly efficient catalysts for asymmetric transfer hydrogenation of aromatic ketones in aqueous medium显示文摘 | LIU G GU H SUN Y | | 0,,08: | 2 |
| 7 | Magnetically recoverable SiO2-coated Fe3O4 nanoparticles:a new platform for asymmetric transfer hydrogenation of aromatic ketones in aqueous medium显示文摘 | SUN Y LIU G GU H | | 0,,09: | 2 |
| 8 | Research on Service Life Prediction Model of Concrete Structure of Sea-crossing Bridge显示文摘According to the chloride corrosion environment,service life prediction model of concrete structure of sea-crossing bridge was built using modified Fick's second law and the whole probability calculation method,which was suitable for China. Furthermore,a visual service life prediction program of concrete structure was developed by optimized Monte Carlo method. Meanwhile,Life 365 program was compared,indicating reliability of the prediction program. Finally,the validity of prediction model was verified in JinTang Bridge of Zhoushan Island Mainland Linkage Project. | WANG C J ZHANG G Z LIU K X TU L Q LI J H QIN M Q | 2010 | 武汉理工大学学报2010,32,17: | 2 |
| 9 | Introduction and constitutive expression of rice chitinase gene in bread wheat using biolistic bombardment and the bar gene as a selectable maker显示文摘 | Chen W P Gu X Liang G H Muthukrishnan S Chen P D Liu D J Giu B S | 1998 | Theor Appl Genet1998,97,12: | 2 |
| 10 | Terahertz Semiconductor Quantum Well Devices显示文摘For eventually providing terahertz science with compact and convenient devices,terahertz (1~10THz) quantum-well photodetectors and quantum-cascade lasers are investigated.The design and projected detector performance are presented together with experimental results for several test devices,all working at photon energies below and around optical phonons.Background limited infrared performance (BLIP) operations are observed for all samples (three in total),designed for different wavelengths.BLIP temperatures of 17,13,and 12K are achieved for peak detection frequencies of 9.7THz(31μm),5.4THz(56μm),and 3.2THz(93μm),respectively.A set of THz quantum-cascade lasers with identical device parameters except for doping concentration is studied.The δ-doping density for each period varies from 3.2×1010 to 4.8×1010cm-2.We observe that the lasing threshold current density increases monotonically with doping concentration.Moreover,the measurements for devices with different cavity lengths provide evidence that the free carrier absorption causes the waveguide loss also to increase monotonically.Interestingly the observed maximum lasing temperature is best at a doping density of 3.6×1010cm-2. | Liu H C Luo H Ban D Waichter M Song C Y Wasilewski Z R Buchanan M Aers G C SpringThorpe A J Cao J C Feng S L Williams B S Hu Q | 2006 | Journal of Semiconductors2006,27,4: | 2 |
| 11 | Three- Dimensional Display of Organs from Computed Tomograms显示文摘 | Herman G T Liu H K | 1979 | Computer Graphics and Image Processing1979,9,1: | 2 |
| 12 | Mitochondrial Control Region Variability of Baiji and the Yangtze Finless Porpoises,two Sympatric Small Cetaceans in the Yangtze River显示文摘 | Yang G Liu S Ren W H | 2003 | Acta Theriologica2003,,48: | 1 |
| 13 | Super plastic bulk metallic glasses at room temperature 显示文摘 | LIU Y H WANG G WANG R J | 2007 | Science2007,315,5817: | 1 |
| 14 | Three-level space vector PWM in low index modulation region avoiding narrow pulse problem显示文摘 | Liu H L Cho G H | 1994 | IEEE Transactions on Power Electronics1994,9,5: | 1 |
| 15 | On the positive definite solutions of the matrix equations X^s ±A^TX^-tA = In显示文摘 | Liu X G Gao H | 2003 | Linear Algebra Appl2003,368,: | 1 |
| 16 | Baculovirus surface display of E2 envelope glycoprotein of classical swine fever virus and immunogenicity of the displayed proteins in a mouse model 显示文摘 | Xu X G Liu H J | 2008 | Vaccine2008,153,11: | 1 |
| 17 | Different responses to selection in two stocks of the bay scallop Argopecten irradians Lamarck (1819) 显示文摘 | Zheng H P Zhang G F Liu X | 2004 | Mar Biol2004,313,: | 1 |
| 18 | Frame Synchronization for Gaussian Channels显示文摘 | Liu G L Tan H H | 1987 | IEEE Transactions on Communications1987,35,08: | 1 |
| 19 | Prediction of crop yield, water consumption and water use efficiency with a SVAT-crop growth model using remotely sensed data on the North China Plain显示文摘 | Mo X G Liu S X Lin Z H | 2005 | Ecological Modelling2005,183,: | 1 |
| 20 | Annealing effects on electrical and optical properties of ZnO thin film samples deposited by radio frequency magnetron sputtering on GaAs(001) substrates显示文摘 | LIU H F CHUA S J HU G X GONG H XIANG N | 2007 | Journal of Applied Physics2007,102,6: | 1 |