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| 1 | Extent of prophylactic postoperative radiotherapy after radical surgery of thoracic esophageal squamous cell carcinoma显示文摘 | J.‐C.Lu H.Tao Y.‐Q.Zhang W.‐W.Zha P.‐D.Qian F.Li K.‐X.Xu | 2008 | Diseases of the Esophagus2008，，6： | 1 |
| 2 | A silk-based self-adaptive flexible opto-electro neural probe显示文摘The combination of optogenetics and electrophysiological recording enables high-precision bidirectional interactions between neural interfaces and neural circuits,which provides a promising approach for the study of progressive neurophysiological phenomena.Opto-electrophysiological neural probes with sufficient flexibility and biocompatibility are desirable to match the low mechanical stiffness of brain tissue for chronic reliable performance.However,lack of rigidity poses challenges for the accurate implantation of flexible neural probes with less invasiveness.Herein,we report a hybrid probe(Silk-Optrode)consisting of a silk protein optical fiber and multiple flexible microelectrode arrays.The Silk-Optrode can be accurately inserted into the brain and perform synchronized optogenetic stimulation and multichannel recording in freely behaving animals.Silk plays an important role due to its high transparency,excellent biocompatibility,and mechanical controllability.Through the hydration of the silk optical fiber,the Silk-Optrode probe enables itself to actively adapt to the environment after implantation and reduce its own mechanical stiffness to implant into the brain with high fidelity while maintaining mechanical compliance with the surrounding tissue.The probes with 128 recording channels can detect high-yield well-isolated single units while performing intracranial light stimulation with low optical losses,surpassing previous work of a similar type.Two months of post-surgery results suggested that as-reported Silk-Optrode probes exhibit better implant-neural interfaces with less immunoreactive glial responses and tissue lesions. | Yu Zhou Chi Gu Jizhi Liang Bohan Zhang Huiran Yang Zhitao Zhou Meng Li Liuyang Sun Tiger H.Tao Xiaoling Wei | 2022 | Microsystems & Nanoengineering2022，8，6： | 1 |
| 3 | 查看详情显示文摘 | H.Q.Xue H.Tao F.Montembault | | 0，，： | 1 |
| 4 | Association of NFKB1 ‐94ins/delATTG promoter polymorphism with susceptibility to autoimmune and inflammatory diseases: a meta‐analysis显示文摘 | Y. F.Zou F.Wang X. L.Feng J. H.Tao J. M.Zhu F. M.Pan H.Su | 2010 | Tissue Antigens2010，，1： | 1 |
| 5 | Long-term flexible penetrating neural interfaces:materials, structures, and implantation显示文摘Penetrating neural interface, which collects the neural electrophysiological signal and serves as a key component in brain-computer interface, has drawn great attention recently. The instability of chronic recording is the main challenge for the conventional neural interface. Novel neural probes with improved long-term performance have been developed based on advanced materials and engineered structures. Here, we review these emergent innovations contributing to chronic stable recording from the perspectives of materials,structures, and implantation methods. These advances make possible further developments in neuroscience research related to neural decoding, neural circuit mechanism analysis, and neurological disease treatment. | Chi GU Jianjuan JIANG Tiger H.TAO Xiaoling WEI Liuyang SUN | 2021 | Science China(Information Sciences)2021，64，12： | 0 |
| 6 | A mosquito mouthpart-like bionic neural probe显示文摘Advancements in microscale electrode technology have revolutionized the field of neuroscience and clinicalapplications by offering high temporal and spatial resolution of recording and stimulation. Flexible neural probes, withtheir mechanical compliance to brain tissue, have been shown to be superior to rigid devices in terms of stability andlongevity in chronic recordings. Shuttle devices are commonly used to assist flexible probe implantation;however, theprotective membrane of the brain still makes penetration difficult. Hidden damage to brain vessels duringimplantation is a significant risk. Inspired by the anatomy of the mosquito mouthparts, we present a biomimeticneuroprobe system that integrates high-sensitivity sensors with a high-fidelity multichannel flexible electrode array.This customizable system achieves distributed and minimally invasive implantation across brain regions. Mostimportantly, the system’s nonvisual monitoring capability provides an early warning detection for intracranial softtissues, such as vessels, reducing the potential for injury during implantation. The neural probe system demonstratesexceptional sensitivity and adaptability to environmental stimuli, as well as outstanding performance in postoperativeand chronic recordings. These findings suggest that our biomimetic neural-probe device offers promising potential forfuture applications in neuroscience and brain-machine interfaces. | Yu Zhou Huiran Yang Xueying Wang Heng Yang Ke Sun Zhitao Zhou Liuyang Sun Jianlong Zhao Tiger H.Tao Xiaoling Wei | 2023 | Microsystems & Nanoengineering2023，9，4： | 0 |
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