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| 1 | Lipids and membrane-associated proteins in autophagy显示文摘Autophagy is essential for the maintenance of cellular homeostasis and its dysfunction has been linked to various diseases.Autophagy is a membrane driven process and tightly regulated by membrane-associated proteins.Here,we summarized membrane lipid composition,and membrane-associated proteins relevant to autophagy from a spatiotemporal perspective.In particular,we focused on three important membrane remodeling processes in autophagy,lipid transfer for phagophore elongation,membrane scission for phago-phore closure,and autophagosome-lysosome membrane fusion.We discussed the significance of the discoveries in this field and possible avenues to follow for future studies.Finally,we summarized the membrane-associated biochemical techniques and assays used to study membrane properties,with a discussion of their applications in autophagy. | Linsen Li Mindan Tong Yuhui Fu Fang Chen Shen Zhang Hanmo Chen Xi Ma Defa Li Xiaoxia Liu Qing Zhong | 2021 | Protein & Cell2021，12，7： | 3 |
| 2 | Evaluation of the risk frequen- cy for hazards of runway incursion in Korea显示文摘 | Dohyun Kim Hanmo Yang | 2012 | Journal of Air Transport Management2012，23，7： | 1 |
| 3 | Porcine reproductive and respiratory syndrome virus activates the transcription of interferon alpha/beta (IFN-α/β) in monocyte-derived dendritic cells (Mo-DC)显示文摘 | Hanmo Zhang Xueshui Guo Eric Nelson Jane Christopher-Hennings Xiuqing Wang | 2012 | Veterinary Microbiology (-)2012，，3： | 1 |
| 4 | Research of NURBS Based Approach for Fitting Contour of Windshield显示文摘 | Zhou Ziqiang Dai Guohong Tan Hanmo | 2013 | Advanced Ma- terials Research2013，，： | 1 |
| 5 | Role of phosphatidylinositol 3-kinase (PI3K) and Akt1 kinase in porcine reproductive and respiratory syndrome virus (PRRSV) replication显示文摘 | Xiuqing Wang Hanmo Zhang Alex M. Abel Alan J. Young Liji Xie Zhixun Xie | 2014 | Archives of Virology2014，，8： | 1 |
| 6 | Evaluation of the risk frequency for hazards of runway incursion in Korea显示文摘 | KIM DOHYUN YANG HANMO | | 0，，： | 1 |
| 7 | Transcriptomic and genetic approaches reveal that low-light-induced disease susceptibility is related to cellular oxidative stress in tomato显示文摘The impact of low light intensities on plant disease outbreaks represents a major challenge for global crop security,as it frequently results in significant yield losses.However,the underlying mechanisms of the effect of low light on plant defense are still poorly understood.Here,using an RNA-seq approach,we found that the susceptibility of tomato to Pseudomonas syringae pv.tomato DC3000(Pst DC3000)under low light was associated with the oxidation-reduction process.Low light conditions exacerbated Pst DC3000-induced reactive oxygen species(ROS)accumulation and protein oxidation.Analysis of gene expression and enzyme activity of ascorbate peroxidase 2(APX2)and other antioxidant enzymes revealed that these defense responses were significantly induced by Pst DC3000 inoculation under normal light,whereas these genes and their associated enzyme activities were not responsive to pathogen inocula-tion under low light.Additionally,the reduced ascorbate to dehydroascorbate(AsA/DHA)ratio was lower under low light compared with normal light conditions upon Pst DC3000 inoculation.Furthermore,the apx2 mutants generated by a CRISPR-Cas9 gene-editing approach were more susceptible to Pst DC3000 under low light conditions.Notably,this increased susceptibility could be significantly reduced by exogenous AsA treatment.Collectively,our findings suggest that low-light-induced disease susceptibility is associated with increased cellular oxidative stress in tomato plants.This study sheds light on the intricate relationship between light conditions,oxidative stress,and plant defense responses,and may pave the way for improved crop protection strategies in low light environments. | Qian Luo Jiao Wang Ping Wang Xiao Liang Jianxin Li Changqi Wu Hanmo Fang Shuting Ding Shujun Shao Kai Shi | 2023 | Horticulture Research2023，10，10： | 0 |
| 8 | Experimental study on seismic reinforcement of bridge foundation on silty clay landslide with inclined interlayer显示文摘A shaking table test for a bridge foundation reinforced by anti-slide piles on a silty clay landslide model with an inclined interlayer was performed.The deformation characteristics of the bridge foundation piles and anti-slide piles were analyzed in different loading conditions.The dynamic response law of a silty clay landslide with an inclined interlayer was summarized.The spacing between the rear anti-slide piles and bridge foundation should be reasonably controlled according to the seismic fortification requirements,to avoid the two peaks in the forced deformation of the bridge foundation piles.The“blocking effect”of the bridge foundation piles reduced the deformation of the forward anti-slide piles.The stress-strain response of silty clay was intensified as the vibration wave field appeared on the slope.Since the vibration intensified,the thrust distribution of the landslide underwent a process of shifting from triangle to inverted trapezoid,the difference in the acceleration response between the bearing platform and silty clay landslide tended to decrease,and the spectrum amplitude near the natural vibration frequency increased.The rear anti-slide piles were able to slow down the shear deformation of the soil in front of the piles and avoid excessive acceleration response of the bridge foundation piles. | Lei Da Xiao Hanmo Ran Jianhua Luo Bin Jiang Guanlu Xue Tianlang | 2024 | Earthquake Engineering and Engineering Vibration2024，23，1： | 0 |
| 9 | Wang Haicheng,Writing and the Ancient State:Early China in Comparative Perspective显示文摘The emergence of Chinese writing and the spread of literacy have remained intriguing,continuously debated topics in the study of early China,especially in the last two decades following the publication of a series of intensively researched,well-crafted Ph.D.dissertations,monographs,and edited volumes in English centered around these subjects. | Hanmo Zhang | 2015 | 浙江大学艺术与考古研究2015，，1： | 0 |
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