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| 1 | RGF1 INSENSITIVE 1 to 5, a group of LRR receptor-like kinases, are essential for the perception of root meristem growth factor I in Arabidopsis thaliana显示文摘RGF1,分泌的肽荷尔蒙,戏在 Arabidopsis 在根分裂组织开发给角色调音。以前的研究显示功能的 RGF1 需要是在由 tyrosylprotein sulfotransferase 的酷氨酸残余的 sulfated 并且 RGF1 主要经由二个下游的抄写因素调整根分裂组织活动,过多 1 (PLT1 ) 并且 PLT2。然而,细胞外的 RGF1 怎么被一个植物房间察觉,是不清楚的。用基因途径,我们发现了充满白氨酸的重复的 clade 像受体的 kinases,指定了为 RGF1 感觉迟钝 1 (RGI1 ) 到 RGI5,用作 RGF1 的受体。二独立 rgi1 rgi2 rgi3 rgi4 rgi5 五倍的异种与分裂组织的一种小尺寸显示一致的短主要的根显型。四倍的异种显示出的 rgi1 rgi2 rgi3 rgi4 到 RGF1 的显著地减少的敏感,和五倍的异种对 RGF1 完全感觉迟钝。PLT1 和 PLT2 的表示在五倍的异种是几乎无法发现的。一个 RGI2 倡导者极大地在五倍的异种驾驶的 PLT2 的宫外的表示救了它的根分裂组织缺点。RGI 之一, RGI1,随后详细生物化学地被分析。在 vitro 点弄污和下拉,分析显示 RGI1 能身体上与 RGF1 交往。RGF1 的外长的申请能快速并且同时导致 RGI1 的 phosphorylation 和 ubiquitination,显示 RGI1 能察觉并且 transduce RGF1 肽信号。然而,激活的 RGI1 多半很快被翻。这些结果表明那 RGI,充当 RGF1 的受体,在在 Arabidopsis thaliana 的 RGF1-PLT-mediated 根分裂组织开发的戏必需品角色。 | Yang Ou Xiaoting Lu Quaner Zi Qingqing Xun Jingjie Zhang Yujun Wu Hongyong Shi Zhuoyun Wei Baolin Zhao Xiaoyue Zhang Kai He Xiaoping Gou Chuanyou Li Jia Li | 2016 | Cell Research2016，26，6： | 18 |
| 2 | Preparation and Characterization of Palladium Colloidal Nanoparticles by Thermal Decomposition of Palladium Acetate with Microwave Irradiation显示文摘A series of solvent-stabilized palladium colloidal nanoparticles were prepared via thermal decomposition of palladium acetate methylisobutylketone (MIBK) solution in the presence of alkali and alcohol with microwave irradiation. The colloidal nanoparticles were characterized with TEM, XPS and XRD. The average diameters of nanoparticles increase from 30 to 40 nm with the increase in concentration of palladium acetate. TEM and XRD observation demonstrated that the palladium colloidal nanoparticles were clusters agglomerated from hundreds of smaller palladium crystallines with size of 3~4 nm. The influence of the concentrations of alkali and alcohol to the particle size was also discussed. | Yixian CHEN, Baolin HE and Hanfan LIU Hubei Key Laboratory for Catalysis and Material Science, University of South-Central for Nationalities, Wuhan 430074, China PCLCC, State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China | 2005 | Journal of Materials Science & Technology2005，21，2： | 4 |
| 3 | Laparoscopic abdomino-perineal resection for patients with anorectal malignant melanoma:a report of 4 cases显示文摘Anorectal malignant melanoma is a very rare but lethal disease.Patients with anorectal malignant melanoma commonly complain for changes in bowel habits and rectal bleeding.Therefore,anorectal malignant melanoma is often misdiagnosed as hemorrhoids,polyp or rectal cancer.Surgery is the mainstay of treatment for patients with anorectal malignant melanoma.However,whether abdominoperineal resection or wide local excision is the most appropriate surgical approach is still a controversial issue.Recently,with the great development of laparoscopic techniques,more and more operations can be performed by laparoscopic techniques.However,laparoscopic abdominoperineal resection for management of anorectal malignant melanoma has been rarely reported.In this study,we reported 4 patients with anorectal malignant melanoma underwent laparoscopic abdominoperineal resection.The outcomes of these patients were relatively good during a long time follow-up.Meanwhile,we reviewed the relevant studies with particular focus surgical treatment. | Jun Han Chuanbing Shi Xiaogang Dong Jie Wang Hao Wen Baolin Wang Zhenyu He | 2016 | The Journal of Biomedical Research2016，30，5： | 3 |
| 4 | Qualitative and quantitative analyses of influenza virus receptors in trachea and lung tissues of humans,mice,chickens and ducks显示文摘To accurately determine the expression and distribution patterns of two influenza virus receptors(SA 2,3-gal and SA 2,6-gal) in trachea and lung tissues of humans,mice,chickens and ducks,we analyzed lectin immunofluorescence stainings of various tissue sections qualitatively and quantitatively.Results from the qualitative analysis showed that both influenza virus receptors were expressed in lung tissues of humans,mice,chickens and ducks as well as trachea tissues of mice and ducks.However,SA 2,6-gal receptor was expressed only in the human trachea tissue and SA 2,3-gal receptor was expressed only in the chicken trachea tissue.Results from the quantitative analysis demonstrated that both receptors were expressed in trachea tissues of human and mouse,as well as in lung tissues of humans,chickens and ducks.Meanwhile,our results also showed that the expression and distribution of influenza virus receptors in the same tissue were not always uniform,indicating that their distribution and expression in various tissues are not simply the distinction between the presence or absence of receptors,but rather the difference in the amount of expressed receptors. | WANG BaoLin LIU Bo CHEN Ling ZHANG JianYong HE HongXuan ZHANG Hong | 2012 | Science China(Life Sciences)2012，55，7： | 2 |
| 5 | Preparation and sintering of Ni-coated Si3N4 composite powders显示文摘 | He Wanbao Zhang Baolin Zhuang Hanrui | | 0，，： | 1 |
| 6 | Injectable Self‑Healing Adhesive pH‑Responsive Hydrogels Accelerate Gastric Hemostasis and Wound Healing显示文摘Endoscopic mucosal resection(EMR)and endoscopic submucosal dissection(ESD)are well-established therapeutics for gastrointestinal neoplasias,but complications after EMR/ESD,including bleeding and perforation,result in additional treatment morbidity and even threaten the lives of patients.Thus,designing biomaterials to treat gastric bleeding and wound healing after endoscopic treatment is highly desired and remains a challenge.Herein,a series of injectable pH-responsive selfhealing adhesive hydrogels based on acryloyl-6-aminocaproic acid(AA)and AA-g-N-hydroxysuccinimide(AA-NHS)were developed,and their great potential as endoscopic sprayable bioadhesive materials to efficiently stop hemorrhage and promote the wound healing process was further demonstrated in a swine gastric hemorrhage/wound model.The hydrogels showed a suitable gelation time,an autonomous and efficient self-healing capacity,hemostatic properties,and good biocompatibility.With the introduction of AA-NHS as a micro-cross-linker,the hydrogels exhibited enhanced adhesive strength.A swine gastric hemorrhage in vivo model demonstrated that the hydrogels showed good hemostatic performance by stopping acute arterial bleeding and preventing delayed bleeding.A gastric wound model indicated that the hydrogels showed excellent treatment effects with significantly enhanced wound healing with type I collagen deposition,α-SMA expression,and blood vessel formation.These injectable self-healing adhesive hydrogels exhibited great potential to treat gastric wounds after endoscopic treatment. | Jiahui He Zixi Zhang Yutong Yang Fenggang Ren Jipeng Li Shaojun Zhu Feng Ma Rongqian Wu Yi Lv Gang He Baolin Guo Dake Chu | 2021 | Nano-Micro Letters2021，13，5： | 1 |
| 7 | 显示文摘 | He Wanbao Zhang Baolin Zhuang Hanrui | 2004 | Ceram Inter2004，30，： | 1 |
| 8 | Influence of land terracing on agricultural and ecological environment in the loess plateau regions of China 显示文摘 | Liu Xiuhua He Baolin Li Zaoxia | 2011 | Environ Earth Sci2011，62，： | 1 |
| 9 | Preparation and sintering of Ni - coated Si3N4 composite powders 显示文摘 | HE WANBAO ZHANG BAOLIN ZHUANG HANRUI | 2005 | Ceramics International2005，，5： | 1 |
| 10 | Combustion synthesis of Si 3 N 4 –TiN composite powders显示文摘 | He Wanbao Zhang Baolin Zhuang Hanrui Li Wenlan | 2004 | Ceramics International2004，，8： | 1 |
| 11 | Synthesis of solvent-stabilized colloidal nanoparticles of platinum,rhodium and ruthenium by microwave-polyol process显示文摘 | He Baolin Chen Yixian Liu Hanfan | 2005 | J Nanosci Nanotech2005，5，2： | 1 |
| 12 | Synthesis of size controlled Ag nanoparticles 显示文摘 | HE Baolin TAN Jueijuei LIEW K0ngyong LIU Han- fan | 2004 | Journal of Molecular Catalysis A2004，221，： | 1 |
| 13 | The potential of carcinoembryonic antigen,p53,Ki-67 and glutathion Stransferase-π as clinico-histopathological markers for colorectal cancer显示文摘Objective:Colorectal cancer is one of the major contributors to cancer death worldwide.Lack of reliable colorectal cancer markers has hampered the management of these cancer patients.Our main purpose was to study the correlation between histopathological variables of colorectal adenocarcinomas and identify histopathological markers that are of prognostic value in patients with colorectal cancer.Methods:In the present study,we examined the expression of carcinoembryonic antigen(CEA),p53,Ki-67 and glutathion Stransferase(GST)-πby using immunohistochemical staining methods in 126 colorectal carcinoma patients and evaluated the lymph node metastasis status in these patients by histopathological examination.Results:The positive rates of CEA,p53, Ki-67 and GST-πexpression in the colorectal cancer tissue specimens examined were 95.23%,55.56%,53.38% and 82.30%,respectively.Expression of p53 and Ki-67 was significantly correlated with the Dukes stages of the tumor,with higher levels of these proteins in Dukes'C and D tumors than those in Dukes'A and B tumors. Furthermore,the expression of p53,GST-πand Ki-67 correlated with prognosis of patients with colorectal cancer. Additionally,the expression of p53 in colorectal cancer was closely related to the expression of Ki-67 and the expression of GST-πwas directly correlated with that of p53.Conclusion:The expression of CEA,p53,Ki-67 and GST-πwas correlated with various clinical features of patients with colorectal cancer.The combined use of these histopathological markers appeared to be a promising tool in predicting the prognosis of patients with this type of cancer. | Zhenyu He Chuanbing Shi Hao Wen Fanglong Li Baolin Wang Jie Wang | 2010 | The Journal of Biomedical Research2010，24，1： | 1 |
| 14 | Preparation and sintering of Ni-coated Si3N4 composite powders 显示文摘 | He Wanbao Zhang Baolin Zhuang Hanrui | 2005 | Ceram Int2005，31，6： | 1 |
| 15 | Synthesis of solvent-stabilized colloidal nanoparticles of Platinum,Rhodium and Ruthenium by microwave-polyol process显示文摘 | He Baolin Chen Yixian Liu Hanfan | 2004 | Journal of nanoscience and nanotechnology2004，5，： | 1 |
| 16 | Synthesis of solvent-stabilized colloidal nanoparticles of platinum,rhodium and ruthenium by microwave-polyol process显示文摘 | He Baolin Chen Yixian Liu Hanfan | 2005 | Journal of Nanoscience and Nanotechnology2005，5，2： | 1 |
| 17 | The Performances of Weak Receiving System of Zhoushan and Its Improving Measures显示文摘 | BAI Jimin ZHANG Baolin HE Dayu | 1988 | Proceedings of the CSEE1988，8，6： | 1 |
| 18 | Sand-mediated ice seeding enables serum-free low-cryoprotectant cryopreservation of human induced pluripotent stem cells显示文摘Human induced pluripotent stem cells(hiPSCs)possess tremendous potential for tissue regeneration and banking hiPSCs by cryopreservation for their ready availability is crucial to their widespread use.However,contemporary methods for hiPSC cryopreservation are associated with both limited cell survival and high concentration of toxic cryoprotectants and/or serum.The latter may cause spontaneous differentiation and/or introduce xenogeneic factors,which may compromise the quality of hiPSCs.Here,sand from nature is discovered to be capable of seeding ice above10◦C,which enables cryopreservation of hiPSCs with no serum,much-reduced cryoprotectant,and high cell survival.Furthermore,the cryopreserved hiPSCs retain high pluripotency and functions judged by their pluripotency marker expression,cell cycle analysis,and capability of differentiation into the three germ layers.This unique sand-mediated cryopreservation method may greatly facilitate the convenient and ready availability of high-quality hiPSCs and probably many other types of cells/tissues for the emerging cell-based translational medicine. | Bin Jiang Weijie Li Samantha Stewart Wenquan Ou Baolin Liu Pierre Comizzoli Xiaoming He | 2021 | Bioactive Materials2021，6，12： | 1 |
| 19 | The difference of clinical characteristics of patients with COVID-19 in Fourth-tier city and Wuhan显示文摘Objective:This study mainly analyzed the clinical characteristics of patients with COVID-19 in Suining,one of China’s fourth-tier cities,and Wuhan and compared data between the 2 cities.Methods:A retrospective analysis of the clinical data of 68 patients with COVID-19 diagnosed at Wuhan Red Cross Hospital and 17 patients diagnosed at Suining Central Hospital,was conducted.Results:Among the 68 patients with COVID-19 in Wuhan,30(44.1%)had hypertension,and 25(36.8%)had diabetes.Three out of the 17 patients in Suining(17.6%)had hypertension,and 2 patients(11.8%)had diabetes.In the clinical classification,there were 1(5.9%)and 23(33.8%)patients with severe COVID-19 in Suining and Wuhan,respectively.Chest CT showed that lung consolidation occurred in 2(11.8%)and 26(38.2%)patients with COVID-19 in Suining and Wuhan,respectively.The proportion of patients with diabetes or hypertension,severe COVID-19,lung consolidation in Wuhan was significantly higher than that in Suining.The laboratory tests suggested that percentage of elevated C-reactive protein(CRP)(58.8%),ALT(33.8%),blood glucose(45.6%),creatine kinase(CK)(33.8%)or D-dimer(47.1%)of patients in Wuhan were significantly increased than those in Suining(29.4%,5.9%,17.6%,5.9%,and 17.7%,respectively).Conclusion:The incidence of COVID-19 in fourth-tier city and the disease severity were significantly lower than that in Wuhan. | Xiaojuan Wu Chaoping Wang Gaoyan He Baolin Jia Li Luo Xiaobin Luo | 2021 | Infectious Diseases Research2021，2，3： | 0 |
| 20 | COVID-19 induces new-onset insulin resistance and lipid metabolic dysregulation via regulation of secreted metabolic factors显示文摘Abnormal glucose and lipid metabolism in COVID-19 patients were recently reported with unclear mechanism.In this study,we retrospectively investigated a cohort of COVID-19 patients without pre-existing metabolic-related diseases,and found new-onset in suli n resista nee,hyperglycemia,and decreased HDL-C in these patie nts.Mecha nistically,SARS-CoV-2 infecti on in creased the expression of RE1-silencing transcription factor(REST),which modulated the expression of secreted metabolic factors including myeloperoxidase,apelin,and myostatin at the transcriptional level,resulting in the perturbation of glucose and lipid metabolism.Furthermore,several lipids,including(±)5-HETE,(±)12-HETE,propionic acid,and isobutyric acid were identified as the potential biomarkers of COVID-19-induced metabolic dysregulation,especially in insulin resistance.Taken together,our study revealed insulin resistance as the direct cause of hyperglycemia upon COVID-19,and further illustrated the underlying mechanisms,providing potential therapeutic targets for COVID-19-induced metabolic complications. | Xi He Chenshu Liu Jiangyun Peng Zilun Li Fang Li Jian Wang Ao Hu Meixiu Peng Kan Huang Dongxiao Fan Na Li Fuchun Zhang Weiping Cai Xinghua Tan Zhongwei Hu Xilong Deng Yueping Li Xiaoneng Mo Linghua Li Yaling Shi Li Yang Yuanyuan Zhu Yanrong Wu Huichao Liang Baolin Liao Wenxin Hong Ruiying He Jiaojiao Li Pengle Guo Youguang Zhuo Lingzhai Zhao Fengyu Hu Wenxue Li Wei Zhu Zefeng Zhang Zeling Guo Wei Zhang Xiqiang Hong Wei kang Cai Lei Gu Ziming Du Yang Zhang Jin Xu Tao Zuo Kai Deng Li Yan Xinwen Chen Sifan Chen Chunliang Lei | 2022 | Signal Transduction and Targeted Therapy2022，7，1： | 0 |
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