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| 1 | Rocky Desertification Risk Zone Delineation in Karst Plateau Area:A Case Study in Puding County,Guizhou Province显示文摘Karst rocky desertification is a geo-ecological problem in Southwest China.The rocky desertification risk zone delineation could be used as a guide for the regional and hierarchical rocky desertification management and prevention.We chose the middle and lower reaches of the Houzhai underground basin on the karst plateau in Puding County, Guizhou Province, China as the study area and selected land use type, elevation, slope, aspect, lithology and settlement buffer as the main driving factors of the rocky desertification.The potential risk of rocky desertification was quantified with the factor-weights union method and statistical analysis method.Five grades of rocky desertification risk were delineated based on Geographic Information System.The extremely low, low, moderate, high and extremely high rocky desertification risk zones accounted for 5.01%, 44.17%, 33.92%, 15.59% and 1.30%, respectively.As a whole, the rocky desertification risk level was moderate because the area of low and moderate rocky desertification risk zones occupied 78.09% of the study area.However, more than half of the area(about 50.81%) was predicted to have moderate rocky desertification risk and above, indicating that the study area was subject to rocky desertification.Rocky desertification risk was higher in the southeast and lower in the northwest of the study area.Distinct differences in the distribution of rocky desertification risk zones corresponding to different factors have been found. | ZHANG Panpan HU Yuanman XIAO Duning LI Xiuzhen YIN Jie HE Hong S | 2010 | Chinese Geographical Science2010，20，1： | 15 |
| 2 | p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulation显示文摘Pancreatic cancer is one of the most aggressive and lethal malignancies worldwide, with a very poor prognosis and a five-year survival rate less than 8%. This dismal outcome is largely due to delayed diagnosis, early distant dissemination and resistance to conventional chemotherapies. Kras mutation is a well-defined hallmark of pancreatic cancer, with over 95% of cases harbouring Kras mutations that give rise to constitutively active forms of Kras. As important down-stream effectors of Kras, p21-activated kinases(PAKs) are involved in regulating cell proliferation, apoptosis, invasion/migration and chemo-resistance. Immunotherapy is now emerging as a promising treatment modality in the era of personalized anti-cancer therapeutics. In this review, basic knowledge of PAK structure and regulation is briefly summarised and the pivotal role of PAKs in Kras-driven pancreatic cancer is highlighted in terms of tumour biology and chemoresistance. Finally, the involvement of PAKs in immune modulation in the tumour microenvironment is discussed and the potential advantages of targeting PAKs are explored. | Kai Wang Graham S Baldwin Mehrdad Nikfarjam Hong He | 2018 | World Journal of Gastroenterology2018，24，33： | 7 |
| 3 | International experts consensus guidelines on robotic liver resection in 2023显示文摘The robotic liver resection(RLR)has been increasingly applied in recent years and its benefits shown in some aspects owing to the technical advancement of robotic surgical system,however,controversies still exist.Based on the foundation of the previous consensus statement,this new consensus document aimed to update clinical recommendations and provide guidance to improve the outcomes of RLR clinical practice.The guideline steering group and guideline expert group were formed by 29 international experts of liver surgery and evidence-based medicine(EBM).Relevant literature was reviewed and analyzed by the evidence evaluation group.According to the WHO Handbook for Guideline Development,the Guidance Principles of Development and Amendment of the Guidelines for Clinical Diagnosis and Treatment in China 2022,a total of 14 recommendations were generated.Among them were 8 recommendations formulated by the GRADE method,and the remaining 6 recommendations were formulated based on literature review and experts’opinion due to insufficient EBM results.This international experts consensus guideline offered guidance for the safe and effective clinical practice and the research direction of RLR in future. | Rong Liu Mohammed Abu Hilal Go Wakabayashi Ho-Seong Han Chinnusamy Palanivelu Ugo Boggi Thilo Hackert Hong-Jin Kim Xiao-Ying Wang Ming-Gen Hu Gi Hong Choi Fabrizio Panaro Jin He Mikhail Efanov Xiao-Yu Yin Roland S Croner Yu-Man Fong Ji-Ye Zhu Zheng Wu Chuan-Dong Sun Jae Hoon Lee Marco V Marino Iyer Shridhar Ganpati Peng Zhu Zi-Zheng Wang Ke-Hu Yang Jia Fan Xiao-Ping Chen Wan Yee Lau | 2023 | World Journal of Gastroenterology2023，29，32： | 2 |
| 4 | Responses of Tree Species to Climate Warming at Different Spatial Scales显示文摘Tree species respond to climate change at multiple scales,such as species physiological response at fine scale and species distribution (quantified by percent area) at broader spatial scale.At a given spatial scale,species physiological response and distribution can be correlated positively or negatively.The consistency of such correlation relationships at different spatial scales determines whether species responses derived from local scales can be extrapo-lated to broader spatial scales.In this study,we used a coupled modeling approach that coupled a plot-level ecosystem process model (LINKAGES) with a spatially explicit landscape model (LANDIS).We investigated species physio-logical responses and distribution responses to climate warming at the local,zonal and landscape scales respectively,and examined how species physiological response and distribution correlated at each corresponding scale and whether the correlations were consistent among these scales.The results indicate that for zonal and warming-sensitive species,the correlations between species physiological response and distribution are consistent at these spatial scales,and therefore the research results of vegetation response to climate warming at the local scale can be extrapolated to the zonal and landscape scales.By contrast,for zonal and warming-insensitive species the correlations among different spatial scales are consistent at some spatial scales but at other scales.The results also suggest that the results of azonal species at the local scale near their distribution boundaries can not be extrapolated simply to broader scales due to stronger responses to climate warming in those boundary regions. | LIANG Yu HE Hong S LEWIS Bernard L | 2011 | Chinese Geographical Science2011，21，4： | 2 |
| 5 | Laser clad Ni-base alloy added nano- and micron-size CeO2 composites显示文摘 | Zhang S H Li M X Tong Yul Cho Jae Hong Yoon Chan Gyu Lee and He Y Z | 2008 | Optics & Laser Technology2008，40，5： | 1 |
| 6 | Controlled topology simplification显示文摘 | HE T S HONG L C | 1996 | IEEE Transactions on Visualization and Computer Graphics1996，2，2： | 1 |
| 7 | Electrospun Ti()2 nanofiber-based cell capture assay for detecting circulating tumor cells from colorectal and gastric cancer patients 显示文摘 | Zhang N Deng Y Tai Q Cheng B Zhao L Shen Q He R Hong L Liu W Guo S | 2012 | Advanced Materials2012，24，20： | 1 |
| 8 | Linearly interpolated sub- symbol optical phase noise suppression in CO-OFDM sys- tem 显示文摘 | HONG X' HONG X HE S | 2015 | Optics Express2015，23，4： | 1 |
| 9 | Linearly interpolated sub-sym- bol optical phase noise suppression in CO-OFDM system 显示文摘 | Hong X Hong X He S | 2015 | Optics Express2015，23，4： | 1 |
| 10 | Low-complexity opti- cal phase noise suppression in CO-OFDM system using re- cursive principal components elimination 显示文摘 | HONG X J HONG X Z HE S L | 2015 | Optics Ex- press2015，23，24： | 1 |
| 11 | Linearly interpolated sub-symbol optical phase noise suppression in CO-OFDM system显示文摘 | HONG X Z HONG X J HE S L | 2015 | Optics Express2015，23，4： | 1 |
| 12 | Reliable path for virtual endoscopy: Ensuring complete examination of human organs 显示文摘 | HE T S HONG L CHEN D Q | 2001 | IEEE Transaction on Visualization and Computer Graphics2001，7，4： | 1 |
| 13 | Fever with Thrombocytopenia associated with a novel bunyavirus in China显示文摘 | Yu X J Liang M F Zhang S Y Liu Y Li J D Sun Y L Zhang L H Zhang Q F Popov V L Li C Qu J Li Q Zhang Y P Hai R Wu W Wang Q Zhan F X Wang X J Kan B Wang SW Wan K L Jing H Q Lu J X Yin W W Zhou H Guan X H Liu J F Bi Z Q Liu G H Ren J Wang H Zhao Z Song J D He J R Wan T Zhang J S Fu X P Sun L N Dong X P Feng Z J Yang W Z Hong T Zhang Y Walker D H Wang Y Li D X | 2011 | N Engl J Med2011，364，16： | 1 |
| 14 | Fever with thrombocytopenia associated with a novel bunyavirus in China显示文摘 | Yu X J Liang M F Zhang S Y Liu Y Li J D Sun Y L Zhang L Zhang Q F Popov V L Li C Qu J Li Q Zhang Y P Hai R Wu W Wang Q Zhan F X Wang X J Kan B Wang S W Wan K L Jing H Q Lu J X Yin W W Zhou H Guan X H Liu J F Bi Z Q Liu G H Ren J Wang H Zhao Z Song J D He J R Wan T Zhang J S Fu X P Sun L N Dong X P Feng Z J Yang W Z Hong T Zhang Y Walker D H Wang Y Li D X | 2011 | N Engl J Med2011，364，： | 1 |
| 15 | Adsorption Thermodynamics of Methylene Blue onto Bentonite 显示文摘 | Hong S Wen C He J | 2009 | Journal of Hazardous materials2009，167，123： | 1 |
| 16 | Terahertz wave switch based on silicon photonic crystals显示文摘 | LI J S HE J L HONG Z | 2007 | Applied Optics2007，46，22： | 1 |
| 17 | Metabolism of nicotine and cotinine by human cytochrome P450 2A13显示文摘 | Bao Z He XY Ding X Prabhu S Hong JY | 2005 | Drug Metab Dispos2005，33，2： | 1 |
| 18 | Capecitabine 'metronomic' chemotherapy for palliative treatment of elderly patients with ad- vanced gastric cancer after fluoropyrimidine-based chemother- apy 显示文摘 | He S ShenJ Hong L eta1 | 2012 | MedOncol2012，29，1： | 1 |
| 19 | MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligand显示文摘 | Sayed D He M Hong C Gao S Rane S Yang Z | 2010 | J Biol Chem2010，285，20： | 1 |
| 20 | Tree Planting:How Fast Can It Accelerate Post-fire Forest Restoration?——A Case Study in Northern Da Hinggan Mountains,China显示文摘In 1987,a catastrophic fire burned over 1330000 ha in the densely forested area of the Da Hinggan Mountains in the northeastern China.After the fire,intensive management including burned trunk harvesting and coniferous tree planting had been conducted to accelerate forest restoration.To study the long term effect of these activities on forest recovery,we used a simulation modeling approach to study long-term(300 years) forest dynamics under current planting and natural regeneration scenarios.Results indicate that under tree planting scenario in the severely burned area,the dominant species Dahurian larch(Larix gmelinii) can reach pre-fire level(60% of the area) within 20 years and the maximum abundance can reach nearly 90% within 100 years.While under natural regeneration scenario,it needs about 250 years to reach its pre-fire level.From the perspective of timber production,tree planting can bring twice as much timber volume as that under natural regeneration within 300 years,which is the average longevity of L.gmelinii.It needs about 70 years to reach the timber volume of pre-fire level under the planting scenario,whereas it requires at least 250 years to reach the timber volume of pre-fire level under natural regeneration scenario.Another dominant species Asian White birch(Betula platyphylla) responded negatively to the planting of coniferous species.In general,tree planting of coniferous species after fire can greatly accelerate forest restoration in terms of species abundance and target timber volume,with desirable ecological and economic returns. | LI Xiuzhen HE Hong S WANG Xugao XIE Fuju HU Yuanman LI Yuehui | 2010 | Chinese Geographical Science2010，20，6： | 1 |
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