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| 1 | International consensus statement on robotic hepatectomy surgery in 2018显示文摘The robotic surgical system has been applied in liver surgery. However,controversies concerns exist regarding a variety of factors including the safety,feasibility, efficacy, and cost-effectiveness of robotic surgery. To promote the development of robotic hepatectomy, this study aimed to evaluate the current status of robotic hepatectomy and provide sixty experts' consensus and recommendations to promote its development. Based on the World Health Organization Handbook for Guideline Development, a Consensus Steering Group and a Consensus Development Group were established to determine the topics, prepare evidence-based documents, and generate recommendations. The GRADE Grid method and Delphi vote were used to formulate the recommendations. A total of 22 topics were prepared analyzed and widely discussed during the 4 meetings. Based on the published articles and expert panel opinion, 7 recommendations were generated by the GRADE method using an evidence-based method, which focused on the safety, feasibility, indication,techniques and cost-effectiveness of hepatectomy. Given that the current evidences were low to very low as evaluated by the GRADE method, further randomized-controlled trials are needed in the future to validate these recommendations. | Rong Liu Go Wakabayashi Hong-Jin Kim Gi-Hong Choi Anusak Yiengpruksawan Yuman Fong Jin He Ugo Boggi Roberto I Troisi Mikhail Efanov Daniel Azoulay Fabrizio Panaro Patrick Pessaux Xiao-Ying Wang Ji-Ye Zhu Shao-Geng Zhang Chuan-Dong Sun Zheng Wu Kai-Shan Tao Ke-Hu Yang Jia Fan Xiao-Ping Chen | 2019 | World Journal of Gastroenterology2019，25，12： | 23 |
| 2 | International experts consensus guidelines on robotic liver resection in 2023显示文摘The robotic liver resection(RLR)has been increasingly applied in recent years and its benefits shown in some aspects owing to the technical advancement of robotic surgical system,however,controversies still exist.Based on the foundation of the previous consensus statement,this new consensus document aimed to update clinical recommendations and provide guidance to improve the outcomes of RLR clinical practice.The guideline steering group and guideline expert group were formed by 29 international experts of liver surgery and evidence-based medicine(EBM).Relevant literature was reviewed and analyzed by the evidence evaluation group.According to the WHO Handbook for Guideline Development,the Guidance Principles of Development and Amendment of the Guidelines for Clinical Diagnosis and Treatment in China 2022,a total of 14 recommendations were generated.Among them were 8 recommendations formulated by the GRADE method,and the remaining 6 recommendations were formulated based on literature review and experts’opinion due to insufficient EBM results.This international experts consensus guideline offered guidance for the safe and effective clinical practice and the research direction of RLR in future. | Rong Liu Mohammed Abu Hilal Go Wakabayashi Ho-Seong Han Chinnusamy Palanivelu Ugo Boggi Thilo Hackert Hong-Jin Kim Xiao-Ying Wang Ming-Gen Hu Gi Hong Choi Fabrizio Panaro Jin He Mikhail Efanov Xiao-Yu Yin Roland S Croner Yu-Man Fong Ji-Ye Zhu Zheng Wu Chuan-Dong Sun Jae Hoon Lee Marco V Marino Iyer Shridhar Ganpati Peng Zhu Zi-Zheng Wang Ke-Hu Yang Jia Fan Xiao-Ping Chen Wan Yee Lau | 2023 | World Journal of Gastroenterology2023，29，32： | 2 |
| 3 | Prognostic implications of tumor invasion or adhesion to peripancreatic vessels in resected pancreatic cancer显示文摘 | Ugo Boggi Marco Del Chiaro Chiara Croce Fabio Vistoli Stefano Signori Carlo Moretto Gabriella Amorese Salvatore Mazzeo Carla Cappelli Daniela Campani Franco Mosca | 2009 | Surgery2009，，： | 1 |
| 4 | Prognostic value of histological grading in ductal adenocarcinoma of the pancreas显示文摘 | Pier Cristoforo Giulianotti Ugo Boggi Gino Fornaciari Joseph Bruno Giuseppe Rossi Demostene Giardino Giulio Candio Franco Mosca | 1995 | International Journal of Pancreatology1995，，3： | 1 |
| 5 | Crizotinib Inhibits Metabolic Inactivation of Gemcitabine in c-Met–driven Pancreatic Carcinoma显示文摘 | Amir Avan Viola Caretti Niccola Funel Elena Galvani Mina Maftouh Richard J. Honeywell Tonny Lagerweij Olaf Van Tellingen Daniela Campani Dieter Fuchs Henk M. Verheul Gerrit-Jan Schuurhuis Ugo Boggi Godefridus J. Peters Thomas Würdinger Elisa Giovannetti | 2013 | Cancer Research2013，，22： | 1 |
| 6 | Laparoscopic pancreaticoduodenectomy: a systematic literature review显示文摘 | Ugo Boggi Gabriella Amorese Fabio Vistoli Fabio Caniglia Nelide De Lio Vittorio Perrone Linda Barbarello Mario Belluomini Stefano Signori Franco Mosca | 2015 | Surgical Endoscopy2015，，1： | 1 |
| 7 | Central pancreatectomy with inframesocolic pancreatojejunostomy显示文摘 | Ugo Boggi Gabriella Amorese Nelide Lio Vittorio Perrone Simone D'Imporzano Chiara Croce Fabio Vistoli Stefano Signori Carla Cappelli Franco Mosca | 2012 | Langenbeck’s Archives of Surgery2012，，6： | 1 |
| 8 | Robotic suture of a large caval injury caused by endo-GIA stapler malfunction during laparoscopic wedge resection of liver segments VII and VIII en-bloc with the right hepatic vein显示文摘 | Ugo Boggi Carlo Moretto Fabio Vistoli Simone D’Imporzano Franco Mosca | 2009 | Minimally Invasive Therapy & Allied Technologies2009，，5： | 1 |
| 9 | Impact of nutritional status on outcome of pancreatic resections for pancreatic cancer and periampullary tumors显示文摘The high complication rate of pancreatic resections and the poor oncologic outcome of pancreatic and periampullary malignancies cannot be explained by just a single factor.There are,however,some underlying elements that affect both surgical outcomes and cancer prognosis.Nutritional status and nutritional support/therapy are among these factors,as they strongly impact on both surgical recovery(1)and cancer survival(2).Additionally,pancreatic cancer entails specific nutritional and metabolic derangements(3)that can lead to immunological deterioration and further enhance tumor aggressiveness(4).Approximately 66%of the patients with pancreas cancer are malnourished(5).Nutritional assessment,support,and therapy are all recommended in pancreatic surgery(1). | Vittorio Grazio Perrone Sara Iacopi Gabriella Amorese Ugo Boggi | 2020 | Hepatobiliary Surgery and Nutrition2020，9，5： | 1 |
| 10 | Genetics of drug response to immunosuppressive treatment and prospects for personalized therapy显示文摘 | Romano Danesi Marta Mosca Ugo Boggi Franco Mosca Mario Del Tacca | 2000 | Molecular Medicine Today2000，，12： | 1 |
| 11 | Incidence, Diagnosis, and Treatment of Chylous Leakage After Laparoscopic Live Donor Nephrectomy显示文摘 | Enzo Capocasale Maurizio Iaria Fabio Vistoli Stefano Signori Maria Patrizia Mazzoni Raffaele Dalla Valle Nelide De Lio Vittorio Perrone Gabriella Amorese Franco Mosca Ugo Boggi | 2012 | Transplantation2012，，1： | 1 |
| 12 | Risk factors of extraneural spreading in astrocytomas and oligodendrogliomas in donors with gliomas: A systematic review显示文摘BACKGROUND Patients with a history of primary brain tumors can be eligible for organ donation under extended criteria.The risk assessment of tumor transmission via organ transplant in primary brain tumors is primarily based on the assessment of tumor histotype and grade.Previous surgeries,chemo-/radiotherapy,and ventriculoperitoneal shunt placement can lead to a disruption of the blood-brain barrier,concurring to an increase in the transmission risk.AIM To investigate the role of tumor transmission risk factors in donors with oligodendrogliomas and astrocytomas.METHODS We searched PubMed and EMBASE databases for studies reporting extraneural spreading of oligoden-drogliomas and astrocytomas and extracted clinical-pathological data on the primary tumor histotype and grade,the elapsed time from the diagnosis to the onset of metastases,sites and number of metastases,prior surgeries,prior radiotherapy and/or chemotherapy,ventriculoatrial or ventriculo-peritoneal shunt placement,and the presence of isocitrate dehydrogenase 1/2 mutation and 1p/19q codeletion.Statistical analysis was performed using R software.Statistical correlation between chemotherapy or radiotherapy and the presence of multiple extra-central nervous system metastases was analyzed usingχ2 and Fischer exact test.The Kaplan-Meier method was used to evaluate the presence of a correlation between the metastasis-free time and:(1)Localization of metastases;(2)The occurrence of intracranial recurrences;and(3)The occurrence of multiple metastases.RESULTS Data on a total of 157 patients were retrieved.The time from the initial diagnosis to metastatic spread ranged from 0 to 325 mo in patients with oligodendrogliomas and 0 to 267 mo in those with astrocytomas.Respectively,19%and 39%of patients with oligodendroglioma and astrocytoma did not receive any adjuvant therapy.The most frequent metastatic sites were bone,bone marrow,and lymph nodes.The lungs and the liver were the most commonly involved visceral sites.There was no significant correlation between the occurrence of multiple metastases and the administration of adjuvant chemo-/radiotherapy.Patients who developed intracranial recurrences/metastases had a significantly longer extraneural metastasis-free time compared to those who developed extraneural metastases in the absence of any intra-central nervous system spread.CONCLUSION A long follow-up time does not exclude the presence of extraneural metastases.Therefore,targeted imaging of bones and cervical lymph nodes may improve safety in the management of these donors. | Serena Ammendola Valeria Barresi Elena Bariani Ilaria Girolami Antonia D’Errico Matteo Brunelli Massimo Cardillo Letizia Lombardini Amedeo Carraro Ugo Boggi Owen Cain Desley Neil Albino Eccher | 2022 | World Journal of Transplantation2022，12，6： | 0 |
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