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| 1 | Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms显示文摘协调的子宫胚胎的轴形成并且蜕膜的改变是哺乳动物的培植以后的胚胎开发的特点。胚胎子宫的取向在起始的培植被决定并且与蜕膜的开发同步。然而,控制这些事件的分子的机制留下尽管有它的发现逃犯很长时间以前。在现在的学习,我们发现了 Rbpj 的那子宫特定的删除,槽口发信号的原子变换器,在培植以后的阶段导致了反常胚胎子宫的取向和蜕膜的 patterning,导致实质的胚胎损失。我们进一步表明在胚胎附件以前, Rbpj 授与在时间上经由身体上与子宫的雌激素受体交往的子宫的腔形状转变(ERα) 以一种槽口小径无关的方式,它为在有子宫的轴的排列的胚胎取向的起始的建立是必要的。当时在培植以后的阶段, Rbpj 直接以一种槽口小径依赖者方式调整子宫的矩阵 metalloproteinase 的表示,它为正常被要求培植以后的蜕膜的改变。这些结果证明子宫的 Rbpj 为经由指示起始的胚胎子宫的取向并且以一种阶段特定的方式保证正常蜕膜的 patterning 的正常胚胎开发是必要的。我们的数据也证实正常哺乳动物的胚胎子宫的取向要求的概念合适的指导从发展地控制了子宫的发信号。 | Shuang Zhang Shuangbo Kong Bingyan Wang Xiaohong Cheng Yongjie Chen Weiwei Wu Qiang Wang Junchao Shi Ying Zhang Shumin Wang Jinhua Lu John P Lydon Francesco DeMayo Warren S Pear Hua Han Haiyan Lin Lei Li Hongmei Wang Yan-ling Wang Bing Li Qi Chen Enkui Duan Haibin Wang | 2014 | Cell Research2014，24，8： | 12 |
| 2 | Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial显示文摘 | Eric Lawitz Fred F Poordad Phillip S Pang Robert H Hyland Xiao Ding Hongmei Mo William T Symonds John G McHutchison Fernando E Membreno | 2013 | The Lancet2013，，： | 5 |
| 3 | The re- lationship of serum AGE levels in diabetic mothers withadverse fetal outcome 显示文摘 | GUOSHENG L HONGMEI S CHUAN N | 2009 | Journal of Perinatology2009，29，7： | 1 |
| 4 | The relationship of serum AGE levels in diabetic mothers with adverse fetal outcome显示文摘 | Guosheng L Hongmei S Chuan N | 2009 | Journal of Perinatology2009，29，7： | 1 |
| 5 | IL-18-induced CD83+CCR7+ NK helper cells显示文摘 | Robbie B Sean M Hongmei S | 2005 | JEM2005，202，5： | 1 |
| 6 | The relationship of serum AGE levels in diabetic mothers with adverse fetal outcome 显示文摘 | Guosheng L Hongmei S Chuan N | 2009 | J Perinatol2009，29，7： | 1 |
| 7 | Timing of recovery from the end-Permian extinction: Geochronologic and biostratigraphic constraints from south China 显示文摘 | Lehrmann D J Rarnezani J Bowfing S A Martin M W Montgomery P Enos P Payne J L Orchard M J Wang Hongmei Wei Jiayong | 2006 | Geology2006，34，： | 1 |
| 8 | Integrated biostratigraphy, magne- tostratigraphy, and geochronolgy of the Olenekian -- Anisian boundary in marine strata of Guandao section, Nanpanjiang Basin, south Chi- na : Implications for timing of biotic recovery from the end-Permian mass extinction 显示文摘 | Wang Hongmei Xiao Jiafei Lehrmann D P Montgomery P P Enos J Orchard M Bowring S A | 2003 | North Central Section Geological Society of Ameri- ca Abstracts with Programs2003，35，2： | 1 |
| 9 | Effects of welding speed on the microstructure and hardness in friction stir welding joints of 6005A-T6 aluminum alloy显示文摘 | Peng D Hongmei L Daqian S | 2013 | Materials and Design2013，45，： | 1 |
| 10 | The relationship of serum AGE levels in diabetic mothers with adverse fetal outcome 显示文摘 | Guosheng L Hongmei S Chuan N | 2009 | J Perinatol2009，29，10： | 1 |
| 11 | The relationship of serum AGE levels in diabetic mothers with adverse fetal outcome 显示文摘 | Guosheng L Hongmei S Chuan N | 2009 | J Perinatol2009，29，10： | 1 |
| 12 | The relationship of serum AGE levels in diabetic mothers with adverse fetal outcome显示文摘 | Guosheng L Hongmei S Chuan N | 2009 | J Perinatol2009，29，7： | 1 |
| 13 | Curcumin mediates presenilin-1 activity to reduce β-amyloid production in a model of Alzheimer's Dis- ease显示文摘 | Xiong Z Hongmei Z Lu S | 2011 | Pharmacol Rep2011，63，5： | 1 |
| 14 | Freezing-sensitive tomato has a functional CBF cold response pathway,but a CBF regulon that differs from that of freezing-tolerant Arabidopsis显示文摘 | Zhang Xin Fowler S G Cheng Hongmei | 2004 | Plant J2004，39，6： | 1 |
| 15 | The low temperature-responsive,Solanum CBF1 genes maintain high identity in their upstream regions in a genomic environment undergoing gene duplications,deletions,and rearrangements显示文摘 | Pennycooke J C Cheng Hongmei Roberts S M | 2008 | Plant Mol Biol2008，67，5： | 1 |
| 16 | The relationship of serum AGE levels in diabetic mothers with adverse fetal outcome 显示文摘 | Guosheng L Hongmei S Chuan N | 2009 | J Perinatol2009，29，： | 1 |
| 17 | The relationship of serum AGE levels in diabetic mothers with adverse fetal outcome 显示文摘 | Guosheng L Hongmei S Chuan N | 2009 | J Perinatol2009，29，48： | 1 |
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