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| 1 | AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells显示文摘The current coronavirus disease 2019(COVID-19)pandemic presents a global public health challenge.The viral pathogen responsible,severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),binds to the host receptor ACE2 through its spike(S)glycoprotein,which mediates membrane fusion and viral entry.Although the role of ACE2 as a receptor for SARS-CoV-2 is clear,studies have shown that ACE2 expression is extremely low in various human tissues,especially in the respiratory tract.Thus,other host receptors and/or co-receptors that promote the entry of SARS-CoV-2 into cells of the respiratory system may exist.In this study,we found that the tyrosine-protein kinase receptor UFO(AXL)specifically interacts with the N-terminal domain of SARS-CoV-2 S.Using both a SARS-CoV-2 virus pseudotype and authentic SARS-CoV-2,we found that overexpression of AXL in HEK293T cells promotes SARS-CoV-2 entry as efficiently as overexpression of ACE2,while knocking out AXL significantly reduces SARS-CoV-2 infection in HI 299 pulmonary cells and in human primary lung epithelial cells.Soluble human recombinant AXL blocks SARS-CoV-2 infection in cells expressing high levels of AXL.The AXL expression level is well correlated with SARS-CoV-2 S level in bronchoalveolar lavage fluid cells from COVID-19 patients.Taken together,our findings suggest that AXL is a novel candidate receptor for SARS-CoV-2 which may play an important role in promoting viral infection of the human respiratory system and indicate that it is a potential target for future clinical intervention strategies. | Shuai Wang Zongyang Qiu Yingnan Hou Xiya Deng Wei Xu Tingting Zheng Peihan Wu Shaofang Xie Weixiang Bian Chong Zhang Zewei Sun Kunpeng Liu Chao Shan Aifu Lin Shibo Jiang Youhua Xie Qiang Zhou Lu Lu Jing Huang Xu Li | 2021 | Cell Research2021，31，2： | 39 |
| 2 | Solvothermal synthesis and luminescent properties of monodisperse LaPO 4 : Ln ( Ln =Eu 3+ , Ce 3+ , Tb 3+ ) particles显示文摘 | Piaoping Yang Zewei Quan Chunxia Li Zhiyao Hou Wenxin Wang Jun Lin | 2009 | Journal of Solid State Chemistry2009，，5： | 1 |
| 3 | A magnetic, luminescent and mesoporous core–shell structured composite material as drug carrier显示文摘 | Piaoping Yang Zewei Quan Zhiyao Hou Chunxia Li Xiaojiao Kang Ziyong Cheng Jun Lin | 2009 | Biomaterials2009，，27： | 1 |
| 4 | A magnetic,luminescent and mesoporous corrshell structured composite material as drug carrier显示文摘 | Yang Piaoping Quan Zewei Hou Zhiyao | 2009 | Biomaterials2009，30，： | 1 |
| 5 | Design method and machine learning application of acoustic holographic computational metamaterials显示文摘Acoustic holographic method has been used in imaging,particle manipulation,material preparation and other fields.In acoustics,it is important to design the implementation of any acoustic wave formation surface[1-5].Traditional methods use piezoelectric arrays to control any acoustic wave array. | LV ZengYao LI JianQing HOU ZeWei DING YuanShuai XU WangDong PEI YongMao | 2022 | Science China(Technological Sciences)2022，65，1： | 0 |
| 6 | On-Surface Synthesis of Na-Porphyrins Using NaCl as a Convenient Na Source显示文摘Metallo-porphyrins with different metal centers display unique properties and are essential in various biological and chemical processes.Enormous efforts have been devoted to enriching the family of metallo-porphyrins on surfaces mainly through metalation processes within porphyrins and exogenous pure metals or intrinsic surface adatoms,which have focused on transition elements.However,less attention has been paid to the synthesis of alkali-metal-based porphyrins on a surface.Herein,by a combination of scanning tunneling microscopy(STM)imaging/manipulations and density functional theory(DFT)calculations,we report the fabrication of Na-porphyrins on Au(111)by introducing NaCl,i.e.,two double-layered Na-centered porphyrins.Moreover,the interconversion between them was realized by precise STM manipulations.Our results demonstrate the feasibility of metalation by applying inorganic salt,which would serve as a promising strategy to embed intramolecular metal components into porphyrins for further functionalization and modification. | Zewei Yi Chi Zhang Zhaoyu Zhang Rujia Hou Yuan Guo Wei Xu | 2023 | Precision Chemistry2023，1，4： | 0 |
| 7 | Wearable Fiber‑Based Supercapacitors Enabled by Additive‑Free Aqueous MXene Inks for Self‑Powering Healthcare Sensors显示文摘Wearable fiber-based electronics have found diverse applications including energy storage,healthcare or thermal management,etc.In particular,additive-free aqueous inks play significant roles in fabrication of wearable fiber-based devices,owning to their nontoxic nature and ease of manufacturing.Herein,wearable carbon fiber-based asymmetric supercapacitors(WASSC)are developed based on additive-free aqueous MXene inks,for self-powering healthcare sensors.The sediments of MXene without further modification are used as inks.Furthermore,combined with additive-free aqueous MXene/polyaniline(MP)inks,WASSC,with a wide voltage window and high capacitance is developed for practical energy supply.Impressively,WASSC has been successfully utilized to power wearable pressure sensors that could monitor motions and pulse signals.This wearable self-powered monitoring system on can accurately monitor the human motions,pronunciation,swallow or wrist pulse,without using the rigid batteries.This advantage realizes a great potential in simple and cost effective monitoring of human health and activities.Besides,self-powered system enables waste recycling of MXene and provides an effective approach for designing wearable and fiber-based self-powered sensors. | Junlin Ma Zewei Cui Yuhang Du Jianxin Zhang Changkai Sun Chengyi Hou Nan Zhu | 2022 | Advanced Fiber Materials2022，4，6： | 0 |
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