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| 1 | Tensile, creep behavior and microstructure evolution of an as-cast Ni-based K417G polycrystalline superalloy显示文摘The Ni-based K417 G superalloy is extensively applied as aeroengine components for its low cost and good mid-temperature(600–900?C) properties. Since used in as-cast state, the comprehensive understanding on its mechanical properties and microstructure evolution is necessary. In the present research,the tensile, creep behavior and microstructure evolution of the as-cast K417 G superalloy under different conditions were investigated. The results exhibit that tensile cracks tend to initiate at MC carbide and γ/γ' eutectic structure and then propagate along grain boundary. As the temperature for tensile tests increases from 21?C to 700?C, the yield strength and ultimate tensile strength of K417 G superalloy decreases slightly, while the elongation to failure decreases greatly because of the intermediate temperature embrittlement. When the temperature rises to 900?C, the yield strength and ultimate tensile strength would decrease significantly. The creep deformation mechanism varies under different testing conditions. At 760?C/645 MPa, the creep cracks initiate at MC carbides and γ/γ' eutectic structures,and propagate transgranularly. While at 900?C/315 MPa and 950?C/235 MPa, the creep cracks initiate at grain boundary and propagate intergranularly. As the creep condition changes from 760?C/645 MPa to 900?C/315 MPa and 950?C/235 MPa, the ? phase starts to raft, which reduces the creep deformation resistance and increases the steady-state deformation rate. | Beining Du Ziyang Hu Liyuan Sheng Chuanyong Cui Jinxia Yang Yufeng Zheng Xiaofeng Sun | 2018 | Journal of Materials Science & Technology2018，34，10： | 4 |
| 2 | Effect of extrusion process on the mechanical and in vitro degradation performance of a biomedical Mg-Zn-Y-Nd alloy显示文摘A new type of biomedical Mg-Zn-Y-Nd alloy was developed and thermal extruded by different processes to investigate the effect of extrusion ratio and extrusion pass on its microstructure,mechanical property and degradation performance.The results show that the increase of extrusion ratio could promote the dynamic recrystallization(DRX)process and led to the coarsening of DRXed grains.While the increase of extrusion pass also contributes to the DRX process but refines the DRXed grains.The simultaneous increasing of extrusion ratio and extrusion pass refines the secondary phases obviously.The increase of extrusion ratio has reduced the tensile strength but improved the elongation of the alloy significantly.However,the increase of extrusion pass could enhance the tensile strength and elongation simultaneously,especially the strength.The degradation performance has been optimized effectively through increasing the extrusion ratio and extrusion pass. | Beining Du Ziyang Hu Jiali Wang Liyuan Sheng Hui Zhao Yufeng Zheng Tingfei Xi | 2020 | Bioactive Materials2020，5，2： | 3 |
| 3 | Chinese consensus guidelines for therapeutic drug monitoring of polymyxin B,endorsed by the Infection and Chemotherapy Committee of the Shanghai Medical Association and the Therapeutic Drug Monitoring Committee of the Chinese Pharmacological Society显示文摘Polymyxin B,which is a last-line antibiotic for extensively drug-resistant Gram-negative bacterial infections,became available in China in Dec.2017.As dose adjustments are based solely on clinical experience of risk toxicity,treatment failure,and emergence of resistance,there is an urgent clinical need to perform therapeutic drug monitoring(TDM)to optimize the use of polymyxin B.It is thus necessary to standardize operating procedures to ensure the accuracy of TDM and provide evidence for their rational use.We report a consensus on TDM guidelines for polymyxin B,as endorsed by the Infection and Chemotherapy Committee of the Shanghai Medical Association and the Therapeutic Drug Monitoring Committee of the Chinese Pharmacological Society.The consensus panel was composed of clinicians,pharmacists,and microbiologists from different provinces in China and Australia who made recommendations regarding target concentrations,sample collection,reporting,and explanation of TDM results.The guidelines provide the first-ever consensus on conducting TDM of polymyxin B,and are intended to guide optimal clinical use. | XIAOFEN LIU CHENRONG HUANG PHILLIP JBERGEN JIAN LI JINGJING ZHANG YIJIAN CHEN YONGCHUAN CHEN BEINING GUO FUPIN HU JINFANG HU LINLIN HU XIN LI HONGQIANG QIU HUA SHAO TONGWEN SUN YU WANG PING XU JING YANG YONG YANG ZHENWEI YU BIKUI ZHANG HUAIJUN ZHU XIAOCONG ZUO YI ZHANG LIYAN MIAO JING ZHANG | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，2： | 1 |
| 4 | Packing Adjustment Towards High Mobility Luminescent Conjugated Polymers显示文摘Next generation display and lighting technology calls for thinner,cheaper and more-flexible unit devices.Polymer light emitting transistor(PLET),which integrates logic function of organic field effect transistor(OFET),luminescence function of organic light emitting diode(OLED),and potential mechanical properties,is believed to be the raising star in this field.However,great challenges remain in developing the core materials of PLETs,which simultaneously require the integration of high ambipolar mobility and strong solid-state luminescence properties.Herein,high mobility luminescent thienopyrroledione-benzodiathiadiazole-fluorene-based conjugated polymer was chosen as polymer backbone,and polymers TBT-1 and TBT-2(TBT=thienopyrroledione-benzodiathiadiazole-thienopyrrole-dione)with red luminescence were obtained by direct arylation polymerization(DArP).By introducing linear alkyl side chains,the packing orientation is changed from face-on in TBT-1 thin film to edge-on in TBT-2 thin film,which is beneficial for improving the field effect performance.The average hole and electron mobility of TBT-2 are 1.1×10^(-2)and 2.0×10^(-3)cm^(2)·V^(-1)·s^(-1),respectively.This work provides new design strategy for high mobility luminescent conjugated polymers,which can be used in PLETs. | ZHANG Yihan LIU Qingqing GAO Can XIE Ziyi HU Beining DONG Huanli | 2023 | Chemical Research in Chinese Universities2023，39，5： | 0 |
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