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| 1 | Emotional regulation of pain:the role of noradrenaline in the amygdala显示文摘The perception of pain involves the activation of the spinal pathway as well as the supra-spinal pathway,which targets brain regions involved in affective and cognitive processes.Pain and emotions have the capacity to influence each other reciprocally;negative emotions,such as depression and anxiety,increase the risk for chronic pain,which may lead to anxiety and depression.The amygdala is a key-player in the expression of emotions,receives direct nociceptive information from the parabrachial nucleus,and is densely innervated by noradrenergic brain centers.In recent years,the amygdala has attracted increasing interest for its role in pain perception and modulation.In this review,we will give a short overview of structures involved in the pain pathway,zoom in to afferent and efferent connections to and from the amygdala,with emphasis on the direct parabrachio-amygdaloid pathway and discuss the evidence for amygdala’s role in pain processing and modulation.In addition to the involvement of the amygdala in negative emotions during the perception of pain,this brain structure is also a target site for many neuromodulators to regulate the perception of pain.We will end this article with a short review on the effects of noradrenaline and its role in hypoalgesia and analgesia. | STROBEL Cornelia HUNT Sarah SULLIVAN Robert SUN JianYuan SAH Pankaj | 2014 | Science China(Life Sciences)2014，57，4： | 7 |
| 2 | 慢性病儿童患者的体力活动(英文)显示文摘In the last two or three decades,physical activity(PA) has gained increasing recognition as being essential for maintaining good health and improving quality of life for all ages.Children have traditionally been active in both free play and organized sports.However,there has been a recent decline in the PA levels among children for various reasons.This lifestyle change has resulted in increased obesity accompanied by a rise in diabetes and cardiovascular risk among otherwise healthy children.These lifestyle changes have been shown to be even more a problem when the child is already affected by a chronic disease.Due to medical limitations and contraindications,much care must be taken to make certain that these children are involved in the appropriate volume and intensity of exercise.The type of activity must also be given careful consideration to avoid undue risk for the child who may have problems such as poor balance,limited strength,poor vision,or cognitive disability.Further complications are either caused or exacerbated by lack of sufficient PA.The priority beyond concern for safety should be focused on ensuring the highest quality of life possible.The purpose of this review is to examine how PA can benefit children with selected chronic health conditions. | William F. Riner Sarah Hunt Sellhorst | 2013 | Journal of Sport and Health Science2013，2，1： | 3 |
| 3 | Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview显示文摘 | Sarah E Capes Dereck Hunt Klas Malmberg Hertzel C Gerstein | 2000 | The Lancet . 2000 (9206)2000，，9206： | 2 |
| 4 | Stress Hyperglycemia and Prognosis of Stroke in Nondiabetic and Diabetic Patients: A Systematic Overview显示文摘 | Sarah E. Capes Dereck Hunt Klas Malmberg Parbeen Pathak Hertzel C. Gerstein | 2001 | Stroke: Journal of the American Heart Association2001，，10： | 2 |
| 5 | Prospective multicentre randomised controlled trial of early enteral nutrition for patients undergoing major upper gastrointestinal surgical resection显示文摘 | Rachael Barlow Patricia Price Thomas D. Reid Sarah Hunt Geoffrey W.B. Clark Timothy J. Havard Malcolm C.A. Puntis Wyn G. Lewis | 2011 | Clinical Nutrition2011，，5： | 2 |
| 6 | Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview显示文摘 | Sarah E Capes Dereck Hunt Klas Malmberg Hertzel C Gerstein | 2000 | The Lancet2000，，9206： | 1 |
| 7 | Stress Hyperglycemia and Prognosis of Stroke in Nondiabetic and Diabetic Patients: A Systematic Overview显示文摘 | Sarah E. Capes Dereck Hunt Klas Malmberg Parbeen Pathak Hertzel C. Gerstein | 2001 | Stroke: Journal of the American Heart Association2001，，10： | 1 |
| 8 | Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview显示文摘 | Sarah E Capes Dereck Hunt Klas Malmberg Hertzel C Gerstein | 2000 | The Lancet2000，，9206： | 1 |
| 9 | Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients显示文摘 | Hunt D Malmberg K | 2001 | Stroke2001，32，： | 1 |
| 10 | Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview显示文摘 | Sarah E Capes Dereck Hunt Klas Malmberg Hertzel C Gerstein | 2000 | The Lancet2000，，9206： | 1 |
| 11 | Infection does not increase long-term mortality in patients with acute severe alcoholic hepatitis treated with corticosteroids显示文摘AIM To determine whether infection in patients with acute severe alcoholic hepatitis(AAH) treated with corticosteroids is associated with increased mortality.METHODS Consecutive patients with AAH were treated with steroids and recruited to the study. Clinically relevant infections(body temperature > 38 ℃ or < 36 ℃ for more than 4 h, ascitic neutrophil count > 0.25 ×109/L, consolidation on chest radiograph or clinically relevant positive microbiological culture of bodily fluid) were recorded prospectively. Clinical and laboratory parameters were recorded and survival at 90 d and 6 mo was determined. Univariate analysis of factors associated with 90-d mortality was performed and significant variables included in a multivariate analysis.RESULTS Seventy-two patients were included in the final analysis(mean age 47.9 years, 26% female, mean discriminant function 53.0). Overall mortality in the group occurred in 15(21%), 23(32%) and 31(43%) at day 28, day 90 and 1 year respectively. 36(50%) had a clinically relevant infection during their hospitalisation(23 after initiation of steroids). The median time to development of incident infection after commencement of steroids was 10 d. The commonest site of infection was ascites(31%) and bacteraemia(31%) followed by urinary tract(19%) and respiratory tract(8%). Forty-one separate organisms were isolated in 33 patients; the most frequent genus was Escherichia(22%) and Enterococcus(20%). Infection was not associated with 90-d or 1 year mortality but was associated with higher creatinine, model for end-stage liver disease and Lille score. Baseline urea was the only independent predictor of 90-d mortality.CONCLUSION Clinically relevant infections are common in patients with AAH but are not associated with increased 90-d or 1 year mortality. | Ashwin D Dhanda Ashish Sinha Vicky Hunt Sarah Saleem Matthew E Cramp Peter L Collins | 2017 | World Journal of Gastroenterology2017，23，11： | 1 |
| 12 | Prospective multicentre randomised controlled trial of early enteral nutrition for patients undergoing major upper gastrointestinal surgical resection显示文摘 | Rachael Barlow Patricia Price Thomas D. Reid Sarah Hunt Geoffrey W.B. Clark Timothy J. Havard Malcolm C.A. Puntis Wyn G. Lewis | 2011 | Clinical Nutrition2011，，5： | 1 |
| 13 | Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes:a systematic overview显示文摘 | Sarah E Capes Dereck Hunt Klas Malmberg | 2000 | Lancet2000，355，9206： | 1 |
| 14 | Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview显示文摘 | Sarah E Capes Dereck Hunt Klas Malmberg Hertzel C Gerstein | 2000 | 2000 (9206)2000，，9206： | 1 |
| 15 | Stress Hyperglycemia and Prognosis of Stoke in Nondiahetic and Diabetic Patients, 显示文摘 | Sarah E Dereck Hunt Klas Malmberg | 2001 | Stroke2001，32，10： | 1 |
| 16 | Targeting Protease-Activated Receptor-1 with Cell-Penetrating Pepducins in Lung Cancer显示文摘 | Jaroslaw Cisowski Katie O’Callaghan Athan Kuliopulos John Yang Nga Nguyen Qing Deng Eric Yang Michael Fogel Sarah Tressel Caitlin Foley Anika Agarwal Stephen W. Hunt Tom McMurry Larry Brinckerhoff Lidija Covic | 2011 | The American Journal of Pathology2011，，1： | 1 |
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