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| 1 | An important role of the hepcidin-ferroportin signaling in affecting tumor growth and metastasis显示文摘 | Wenli Guo Shuping Zhang Yue Chen Daoqiang Zhang Lin Yuan Haibo Cong Sijin Liu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，9： | 14 |
| 2 | Preparation of Au nanoparticles modified TiO_2 nanotube array sensor and its application as chemical oxygen demand sensor显示文摘Au nanoparticles(AuNPs) were electrodeposited at the highly ordered anatase TiO_2 nanotube array(TiO_2 NA) electrode under sonicating, and the AuNP-TiO_2 NA sensor was characterized by scanning electron microscope(SEM), X-ray photoelectron spectroscopy(XPS), X-ray diffraction(XRD). The photoelectrochemical experiments indicate the AuNP-TiO_2 NA sensor has lower photoelectro-resistance,higher photoelectrocatalytical activity and stability than that of pure TiO_2 NA sensor under the same conditions. The as-prepared sensor can be used for the determination of chemical oxygen demand(COD)in real samples, and the obtained results are comparable well with those of by standard K_2Cr_2O_7 method.The method proposed is simple, fast, cost effective, and environmentally friendly. | Longqi Liang Jiao Yin Jinpeng Bao Linchuan Cong Weimin Huang Haibo Lin Zhan Shi | 2019 | Chinese Chemical Letters2019，30，1： | 2 |
| 3 | Comparative proteomic analysis of the effects of high-concentrate diet on the hepatic metabolism and inflammatory response in lactating dairy goats显示文摘Background: To understand the impact of feeding a high-concentrate diet to mid-lactating goats for a long time on liver metabolism and inflammatory response, two dimensional polyacrylamide gel electrophoresis(2-DE) and real-time PCR method were employed to detect proteins differentially expressed in liver and their m RNAs expression in goats fed high concentrate diet(HC) or low concentrate diet(LC). Twelve lactating dairy goats were randomly assigned to either a HC diet group(65 % concentrate of dry matter; n = 6) or a LC diet group(35 % concentrate of dry matter; n = 6) for 10 wk.Results: Twenty differentially expressed spots(≥2.0-fold changes) in the hepatic tissues were excised and successfully identified using MALDI TOF/TOF. Of these, 8 proteins were up-regulated, while the rest 12 proteins were down-regulated in HC goats compared to LC. Differential expressed proteins including alpha enolase 1(ENO1), glutamate dehydrogenase 1(GLUD1), glutathione S-transferase A1(GSTA1), ATP synthase subunit 5β(ATP5β), superoxide dismutase [Cu-Zn](SOD1), cytochrom c oxidase subunit Via(COX6A1) and heat shock protein 60(HSP60) were further verified by real-time PCR and/or western blot at m RNA or protein expression level. Consistent with the 2-DE results, a significant decrease of β-actin protein expression and SOD enzyme activity was observed in liver of HC goats(P < 0.05), while ENO1 protein expression was significantly up-regulated in HC compared to LC goats(P < 0.05). However, western blot analysis did not show a significant difference of hepatic HSP60 protein between HC and LC group, which did not match the decrease of HSP60 content detected by 2-DE analysis. Real-time PCR showed that glutathione S-transferase P1(GSTP1) and SOD1 m RNA expression was significantly decreased in liver of HC goats, while cytochrom c oxidase(COX3) and ATPase 8(ATP8) m RNAs expression were markedly increased compared to LC(P < 0.05). Gene Ontology(GO) analysis revealed that HC diet resulted in altered expression of proteins related to catalytic and mitochondrial metabolism in the liver, and may increase the stress response with up-regulating the expression of differentiation 14(CD14) cluster and serum amyloid A(SAA) as well as C-reactive protein(CRP) in the liver.Conclusions: These results suggest that feeding high concentrate diet to lactating goats for 10 wk leads to the activation of the inflammatory response, and decreases the anti-oxidant capacity, and subsequently impairs the mitochondrial function in the liver. | Yongqian Duanmu Rihua Cong Shiyu Tao Jing Tian Haibo Dong Yuanshu Zhang Yingdong Ni Ruqian Zhao | 2016 | Journal of Animal Science and Biotechnology2016，7，2： | 2 |
| 4 | Generation of transgenic golden Syrian hamsters显示文摘 | Mingming Gao Baoyu Zhang Jinjiao Liu Xin Guo Haibo Li Tao Wang Zifu Zhang Jiawei Liao Nathan Cong Yuhui Wang Liqing Dong Zhao George Liu | 2014 | Cell Research2014，24，3： | 2 |
| 5 | Hull deformation measurement for spacecraft TT&C ship by Photogrammetry显示文摘When voyaging,ships are subject to inevitable hull deformations caused by the changes in the environmental temperature and external stress.These are a crucial source of errors when measuring data using a spacecraft tracking,telemetry,and control(TT&C) ship.A prototype system based on photogrammetry was developed for the real-time measurement of a spacecraft TT&C ship's hull deformation.This system has high accuracy,a simple structure,and convenient maintenance,and requires few changes to the ship's structures.To improve its performance,an estimation approach is proposed for hull deformation angles.With the proposed approach,the central positions of cross spots in successive frames can be predicted based on the prediction of the camera's attitude,and their extract locations can be found by defining a series of small windows around each predictive location.Then,the optimal estimate of the camera's attitude is updated by the designed extended Kalman filter using the extracted cross spots and their corresponding local coordinates,with which the hull deformation angles can be found.To verify the proposed measurement approach,its performance was tested during the normal sailing,floating,and rocking on the sea of a spacecraft TT&C ship.The experimental testing results demonstrated that the proposed approach performs well in terms of accuracy and robustness.It can satisfy the hull deformation measurement requirement for a spacecraft TT&C ship in real time. | LIU HaiBo SUN Cong ZHANG YueQiang LIU XinMing LIU JinBo ZHANG XiaoHu YU QiFeng | 2015 | Science China(Technological Sciences)2015，58，8： | 2 |
| 6 | Calcium hydride reduced high-quality Nd-Fe-B powder from Nd-Fe-B sintered magnet sludge显示文摘The structural and magnetic properties were studied for recycling Nd-Fe-B powders from Nd-Fe-B sintered magnets sludge via reduction diffusion(RD)with calcium hydride(CaH_(2))particles.For comparison,traditional reducing agent calcium granules were applied to prepare recycled Nd-Fe-B powders.Finer particle size and better size distribution as well as lower impurity content are achieved by using CaH_(2)instead of Ca.In detail,the average particle size of the recycled Nd-Fe-B powder is reduced from 4.66 to 3.43μm,and the bimodal distribution disappears.Moreover,the residual calcium content and oxygen content are reduced to about 0.080 wt%and 0.32 wt%.As a consequence,the roomtemperature magnetization of the CaH_(2)-recycled Nd-Fe-B powder is increased to 146.30 emu/g,6.8%and 33%,respectively,higher than that of Ca-reduced powder and the initial sludge.Further analysis indicates that CaH_(2)is able to reduce the sludge at lower tempe rature to fabricate well-dispersed,unifo rm recycled powder with high magnetization arising from a combination factors of its low melting point,low thermodynamic behavior,and the release of hydrogen during the reaction. | Haibo Xu Qingmei Lu Liying Cong Haowen Tian Weiqiang Liu Youhao Liu Yunqiao Wang Jingwu chen Xiaofei Yi Ming Yue | 2022 | Journal of Rare Earths2022，40，12： | 1 |
| 7 | Chromosome-scale genome assembly of marigold (Tagetes erecta L.):An ornamental plant and feedstock for industrial lutein production显示文摘Marigold(Tagetes erecta L., African marigold) is a widely grown ornamental plant and a main source of the carotenoid lutein for the industrial production of pharmaceuticals, food coloring, and feed additives. To gain a deeper understanding of the genetic mechanism of lutein in marigold, a chromosome-scale assembly of the marigold(T. erecta V-01) genome was completed based on Illumina, PacBio, and Hi-C reads. The707.21-Mb assembled genome consisted of 35 834 annotated protein-coding genes, with 97.7% genomic integrity. We anchored 87.8% of the contigs(covering 621.20 Mb) to 12 pseudochromosomes, bringing the scaffold N50 length to 54.15 Mb. Phylogenetic analysis showed that marigold was closely related to the Asteraceae species bitter vine(Mikania micrantha) and sunflower(Helianthus annuus), all three of which originated in the Americas. Marigold diverged from the sunflower clade 23.57 million years ago(MYA) and from M. micrantha 19.59 MYA.Marigold has undergone three whole-genome duplication events, as well as a recent whole-genome duplication event(WGD-2) common to H.annuus and M. micrantha. Marigold gene families were significantly less expanded than those of M. micrantha or H. annuus, and the marigold genome contained significantly fewer interspersed repeats, which might account for its smaller genome. In addition, a range of candidate genes involved in the lutein biosynthetic pathway were identified. The high-quality reference genome obtained in this study provided a valuable genomic resource for studying the evolution of the Asteraceae family and for improving marigold breeding strategies. | Haibo Xin Fangfang Ji Jie Wu Shiya Zhang Caijie Yi Shiwei Zhao Richen Cong Liangjun Zhao Hua Zhang Zhao Zhang | 2023 | Horticultural Plant Journal2023，9，6： | 0 |
| 8 | Perturbation of clopyralid on bio-denitrification and nitrite accumulation:Long-term performance and biological mechanism显示文摘The contaminant of herbicide clopyralid(3,6-dichloro-2-pyridine-carboxylic acid,CLP)poses a potential threat to the ecological system.However,there is a general lack of research devoted to the perturbation of CLP to the bio-denitrification process,and its biological response mechanism remains unclear.Herein,long-term exposure to CLP was systematically investigated to explore its influences on denitrification performance and dynamic microbial responses.Results showed that low-concentration of CLP(<15 mg/L)caused severe nitrite accumulation initially,while higher concentrations(35e60 mg/L)of CLP had no further effect after long-term acclimation.The mechanistic study demonstrated that CLP reduced nitrite reductase(NIR)activity and inhibited metabolic activity(carbon metabolism and nitrogen metabolism)by causing oxidative stress and membrane damage,resulting in nitrite accumulation.However,after more than 80 days of acclimation,almost no nitrite accumulation was found at 60 mg/L CLP.It was proposed that the secretion of extracellular polymeric substances(EPS)increased from 75.03 mg/g VSS at 15 mg/L CLP to 109.97 mg/g VSS at 60 mg/L CLP,which strengthened the protection of microbial cells and improved NIR activity and metabolic activities.Additionally,the biodiversity and richness of the microbial community experienced a U-shaped process.The relative abundance of denitrification-and carbon metabolism-associated microorganisms decreased initially and then recovered with the enrichment of microorganisms related to the secretion of EPS and N-acyl-homoserine lactones(AHLs).These microorganisms protected microbe from toxic substances and regulated their interactions among interand intra-species.This study revealed the biological response mechanism of denitrification after successive exposure to CLP and provided proper guidance for analyzing and treating herbicide-containing wastewater. | Suyun Sun Ya-Nan Hou Wei Wei Hafiz Muhammad Adeel Sharif Cong Huang Bing-Jie Ni Haibo Li Yuanyuan Song Caicai Lu Yi Han Jianbo Guo | 2022 | Environmental Science and Ecotechnology2022，，1： | 0 |
| 9 | Electrochemical conversion of furfural to furoic acid:a more stable,efficient and energy-saving system显示文摘The paired electrolytic system is constructed by combining the valuable organic electro-oxidation and electro-reduction reactions,which can replace the ineffective water splitting half-reaction.By reducing the energy consumption of the electrolytic cell,the value-added electrolysis is realized.The indirect electrolysis method greatly reduces the dependence of the organic electrolysis reaction on electrode potential by introducing the redox mediators,which solves the problem on the matching of anode and cathode current under potentiostatic conditions.Here,we report a more stable,efficient and energy-saving linear paired electrochemical synthesis system that can simultaneously convert furfural to furoic acid at both the anode and cathode at higher current densities.Stable three-dimensional networked PbO_(2)is used as the anode and the catalytic amount of 2,2,6,6-tetramethyl-1-piperidinyloxy(TEMPO)is used as the mediator to realize the efficient conversion of furfural to furoic acid in a wide potential range.The cathode catalyzes two-electron oxygen reduction to hydrogen peroxide using Pb/RHPC gas-diffusion electrode,which mediates the oxidation of furfural to furoic acid simultaneously.In potentiostatic electrolysis,the selectivity of the furoic acid in the cathode and anode is 33.2%and 99.3%,respectively,and the total electron efficiency is 127.1%.The properties of the cathode and anode remain stable after the long-time electrolysis in a flow cell.By choosing a stable anode with high oxygen evolution overpotential and a gas-diffusion cathode with high hydrogen evolution overpotential,the electrolytic cell can be operated efficiently and stably by introducing reasonable mediated reactions.The two half-reactions have good compatibility during the electrolysis process,saving energy consumption by about 12.3%,for certain industrial application prospects. | Xinxin Li Linchuan Cong Haibo Lin Fangbing Liu Fuyu Han Nan Lin | 2022 | Science China Chemistry2022，65，12： | 0 |
| 10 | Evaluation of different clean heat supply modes based on crop straws in the rural area of Northern China显示文摘This study evaluated eight different types of heat supply modes based on crop residues utilization in the rural area of Northern China,including straw densified solid fuel combustion,pyrolysis char combustion,biogas combustion,and pyrolysis gas combustion for single household heating;straw densified solid fuel combustion,baling straw combustion,biogas combustion,and pyrolysis gas combustion for centralized heating;centralized gas supply and centralized pyrolysis gas supply modes.Comprehensively evaluation was the cost of these different eight heat supply modes.The results showed that the cost of straw densified solid fuel combustion,pyrolysis char combustion for single household heating were 2346 RMB/household and 2390 RMB/household.With the heating scale of 200-500 households,the pipe network distance was 8 m/household,and the total annual heating cost was predicted at 2201-2992 RMB/household.Among them,the cost of straw baling combustion for centralized heating was the lowest,the cost of densified solid fuel,biogas,and pyrolysis for centralized heating was the second,and the cost of biogas and pyrolysis gas for centralized gas supply was the highest.For the increase in every 1 m of the pipeline distance,the investment cost will increase by about 645 RMB for each household.This study provides a basis for the implementation of clean heat supply technologies in less-developed areas and guidance of village heat-supply subsidy policies. | Lili Huo Zonglu Yao Jixiu Jia Lixin Zhao Hongbin Cong Haibo Meng Yanwen Yuan | 2020 | International Journal of Agricultural and Biological Engineering2020，13，5： | 0 |
| 11 | A facile process to optimize performance of regenerated Nd-Fe-B sintered magnets:Chemo-selective dissolution washing显示文摘In this work,the recycled Nd-Fe-B powders and regenerated Nd-Fe-B sintered magnets with low impurity content were successfully prepared from Nd-Fe-B magnet sludge via reduction diffusion(RD)method followed by a chemo-selective dissolution washing proc ess.The chemo-selective dissolution effect of various solution(deionized water,dilute acetic acid solution,NH_(4)Cl-methanol solution) was evaluated by impurity content and magnetic properties of the recycled Nd-Fe-B powder.The NH_(4)Cl-methanol solution can selectively remove impurities with minimal damage to the magnetic phase.Besides,the optimal NH_(4)Cl concentration and liquid-to-solid ratio were investigated.As a consequence,the contents of Ca,O,and H after optimal washing process are reduced to 0.07 wt%,0.31 wt% and 0.22 wt%,respectively.Hence,M_(3) Tis increased to 146.72 emu/g,which is 33% higher than that of the initial sludge.Then,the regenerated Nd-Fe-B sintered magnets with properties of B_(r)=11.66 kG,H_(cj)=16.49 kOe,and(BH)_(m)=31.78 MGOe were successfully prepared by mixing with 40 wt% Nd4Fe14B alloy powders.Compared with the corresponding regenerated magnets washed with deionized water,the remanence and coercivity are increased by 18% and 59%,respectively. | Haibo Xu Qingmei Lu Lichao Yu Liying Cong Haowen Tian Weiqiang Liu Youhao Liu Yunqiao Wang Jingwu Chen Xiaofei Yi Qiong Wu Ming Yue | 2023 | Journal of Rare Earths2023，41，12： | 0 |
| 12 | Linear paired electrolysis of furfural to furoic acid at both anode and cathode in a multiple redox mediated system显示文摘Implementing a new energy-saving electrochemical synthesis system with high commercial value is a strategy of the sustainable development for upgrading the bulk chemicals preparation technology in the future.Here,we report a multiple redox-mediated linear paired electrolysis system,combining the hydrogen peroxide mediated cathode process with the I2 mediated anode process,and realize the conversion of furfural to furoic acid in both side of the dividedflow cell simultaneously.By reasonably controlling the cathode potential,the undesired water splitting reaction and furfural reduction side reactions are avoided.Under the galvanostatic electrolysis,the two-mediated electrode processes have good compatibility,which reduce the energy consumption by about 22%while improving the electronic efficiency by about 125%.This system provides a green electrochemical synthesis route with commercial prospects. | Xinxin Li Linchuan Cong Haibo Lin Fangbing Liu Xiangxue Fu Hai-Chao Xu Nan Lin | 2024 | Green Energy & Environment2024，9，1： | 0 |
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