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| 1 | Wind-wave hindcast in the Yellow Sea and the Bohai Sea from the year 1988 to 2002显示文摘We performed long-term wind-wave hindcast in the Yellow Sea and the Bohai Sea from the year 1988 to 2002, and then analyzed the regional wave climate. Comparisons between model results and satellite data are generally consistent on monthly mean significant wave height. Then we discuss the temporal and spatial characteristics of the climatological monthly mean significant wave heights and mean wave periods. The climatologically spatial patterns are observed as increasing from northwest to southeast and from offshore to deep-water area for both significant wave height and mean wave period, and the patterns are highly related to the wind forcing and local topography. Seasonal variations of wave parameters are also significant. Furthermore, we compute the extreme values of wind and significant wave height using statistical methods. Results reveal the spatial patterns of N-year return significant wave height in the Yellow Sea and the Bohai Sea, and we discuss the relationship between extreme values of significant wave height and wind forcing. | HE Hailun XU Yao | 2016 | Acta Oceanologica Sinica2016，35，3： | 11 |
| 2 | Interpreting the sea surface temperature warming trend in the Yellow Sea and East China Sea显示文摘Previous studies have demonstrated that the low-frequency sea surface temperature(SST) variability in the Yellow Sea and East China Sea(YECS) is linked to large-scale climate variability, but explanations on the mechanisms vary. This study examines the low-frequency variability and trends of some atmospheric and oceanic variables to discuss their different effects on the YECS warming. The increasing temperature trend is also observed at a hydrographic section transecting the Kuroshio.The increasing rate of ocean temperature decreases with depth, which might result in an increase in vertical stratification and a decrease in vertical mixing, and thus plays a positive role on the YECS warming. The surface net heat flux(downward positive)displays a decreasing trend, which is possibly a result of the YECS warming, and, in turn, inhibits it. Wind speeds show different trends in different datasets, such that its role in the YECS warming is uncertain. The trends in wind stress divergence and curl have large uncertainties, so their effects on SST warming are still unclear. The Kuroshio heat transport calculated in this study,displays no significantly increasing trend, so is an unlikely explanation for the SST warming. Limited by sparse ocean observations,sophisticated assimilative climate models are still needed to unravel the mechanisms behind the YECS warming. | PEI YuHua LIU XiaoHui HE HaiLun | 2017 | Science China Earth Sciences2017，60，8： | 10 |
| 3 | DELLA and EDS1 Form a Feedback Regulatory Module to Fine-Tune Plant Growth-Defense Tradeoff in Arabidopsis显示文摘Plants maintain a dynamic balance between growth and defense,and optimize allocation of resources for survival under constant pathogen infections.However,the underlying molecular regulatory mechanisms,especially in response to biotrophic bacterial infection,remain elusive.Here,we demonstrate that DELLA proteins and EDS1,an essential resistance regulator,form a central module modulating plant growth-defense tradeoffs via direct interaction.When infected by Pst DC3000,EDS1 rapidly promotes salicylic acid(SA)biosynthesis and resistance-related gene expression to prime defense response,while pathogen infection stabilizes DELLA proteins RGA and RGL3 to restrict growth in a partially EDS1-dependent manner,which facilitates plants to develop resistance to pathogens.However,the increasingly accumulated DELLAs interact with EDS1 to suppress SA overproduction and excessive resistance response.Taken together,our findings reveal a DELLA-EDS1-mediated feedback regulatory loop by which plants maintain the subtle balance between growth and defense to avoid excessive growth or defense in response to constant biotrophic pathogen attack. | Yuge Li Yuhua Yang Yilong Hu Hailun Liu Ming He Ziyin Yang Fanjiang Kong Xu Liu Xingliang Hou | 2019 | Molecular Plant2019，12，11： | 8 |
| 4 | Variation of the Kuroshio intrusion pathways northeast of Taiwan using the Lagrangian method显示文摘The seasonal variations of the Kuroshio intrusion pathways northeast of Taiwan were investigated using observational data from satellite-tracked sea surface drifters and a numerical particle-tracking experiment based on a high-resolution numerical ocean model. The results of sea surface drifter data observed from 1989 to 2013 indicate that the Kuroshio surface intrusion follows two distinct pathways: one is a northwestward intrusion along the northern coast of Taiwan Island, and the other is a direct intrusion near the turn of the shelf break. The former occurs primarily in the winter, while the latter exists year round. A particle-tracking experiment in the high-resolution numerical model reproduces the two observed intrusion paths by the sea surface drifters. The three-dimensional structure of the Kuroshio intrusion is revealed by the model results. The pathways, features and possible dynamic mechanisms of the subsurface intrusion are also discussed. | LIU XiaoHui CHEN DaKe DONG ChangMing HE HaiLun | 2016 | Science China Earth Sciences2016，59，2： | 7 |
| 5 | Climate and extrema of ocean waves in the East China Sea显示文摘Wave climate plays an important role in the air-sea interaction over marginal seas. Extreme wave height provides fundamental information for various ocean engineering practices, such as hazard mitigation, coastal structure design, and risk assessment. In this paper, we implement a third generation wave model and conduct a high-resolution wave hindcast over the East China Sea to reconstruct a 15-year wave field from 1988 to 2002 for derivation of monthly mean wave parameters and analysis of extreme wave conditions. The numerical results of the wave field are validated through comparison with satellite altimetry measurements, low-resolution reanalysis, and the ocean wave buoy record. The monthly averaged wave height and wave period show seasonal variation and refined spatial patterns of surface waves in the East China Sea. The climatological significant wave height and mean wave period decrease from the open ocean in the southeast toward the continental area in the northwest, with the pattern generally following the bathymetry. Extreme analysis on the significant wave height at the buoy station indicates the hindcast data underestimate the extreme values relative to the observations. The spatial pattern of extreme wave height shows single peak emerges at the southwest of Ryukyu Island although a wind forcing with multi-core structure at the extreme is applied. | Hailun HE Jinbao SONG Yefei BAI Yao XU Juanjuan WANG Fan BI | 2018 | Science China Earth Sciences2018，61，7： | 7 |
| 6 | Effects of surface waves and sea spray on air–sea fluxes during the passage of Typhoon Hagupit显示文摘Air–sea exchange plays a vital role in the development and maintenance of tropical cyclones(TCs). Although studies have suggested the dependence of air–sea fluxes on surface waves and sea spray, how these processes modify those fluxes under TC conditions have not been sufficiently investigated based on in-situ observations.Using continuous meteorological and surface wave data from a moored buoy in the northern South China Sea,this study examines the effects of surface waves and sea spray on air–sea fluxes during the passage of Typhoon Hagupit. The mooring was within about 40 km of the center of Hagupit. Surface waves could increase momentum flux to the ocean by about 15%, and sea spray enhanced both sensible and latent heat fluxes to the atmosphere,causing Hagupit to absorb 500 W/m^2 more heat flux from the ocean. These results have powerful implications for understanding TC–ocean interaction and improving TC intensity forecasting. | HE Hailun WU Qiaoyan CHEN Dake SUN Jia LIANG Chujin JIN Weifang XU Yao | 2018 | Acta Oceanologica Sinica2018，37，5： | 5 |
| 7 | Paleomagnetic results from Late Carboniferous to Early Permian rocks in the northern Qiangtang terrane, Tibet, China, and their tectonic implications显示文摘Results of a systematic paleomagnetic study are reported based on Late Carboniferous to Early Permian sedimentary rocks on the north slope of the Tanggula Mountains,in the northern Qiangtang terrane(NQT),Tibet,China.Data revealed that magnetic minerals in limestone samples from the Zarigen Formation(CP^z)are primarily composed of magnetite,while those in sandstone samples from the Nuoribagaribao Formation(Pnr)are dominated by hematite alone,or hematite and magnetite in combination.Progressive thermal,or alternating field,demagnetization allowed us to isolate a stable high temperature component(HTC)in 127 specimens from 16 sites which successfully passed the conglomerate test,consistent with primary remnance.The tilt-corrected mean direction for Late Carboniferous to Early Permian rocks in the northern Qiangtang terrane is D_s=30.2°,I_s=-40.9°,k_s=269.0,a_(95)=2.3°,N=16,which yields a corresponding paleomagnetic pole at 25.7°N,241.5°E(dp/dm=2.8°/1.7°),and a paleolatitude of 23.4°S.Our results,together with previously reported paleomagnetic data,indicate that:(1)the NQT in Tibet,China,was located at a low latitude in the southern hemisphere,and may have belonged to the northern margin of Gondwana during the Late Carboniferous to Early Permian;(2)the Paleo-Tethys Ocean was large during the Late Carboniferous to Early Permian,and(3)the NQT subsequently moved rapidly northwards,perhaps related to the fact that the Paleo-Tethys Ocean was rapidly contracting from the Late Permian to Late Triassic while the Bangong Lake-Nujiang Ocean,the northern branch of the Neo-Tethys Ocean,expanded rapidly during this time. | YANG XingFeng CHENG Xin ZHOU YaNan MA Lun ZHANG XiaoDong YAN ZhaoSheng PENG XiMing SU HaiLun WU HanNing | 2017 | Science China Earth Sciences2017，60，1： | 5 |
| 8 | The normal cell proliferation and wound healing effect of polysaccharides from Ganoderma amboinense显示文摘To study the cell proliferation and wound healing activity of polysaccharides from Ganoderma amboinense(GAMPS),the polysaccharide was extracted by water extraction and alcohol precipitation method,and its monosaccharide composition and molecular weight were analyzed.The effects of different concentrations of GAMPS on the cell proliferation were determined by cell survival rate test,and the wound healing ability of GAMPS to NIH/3T3 cells was detected.The preliminary evaluation of the antioxidant ability of GAMPS was conducted by the oxygen radical absorbance capacity(ORAC).The results showed that the GAMPS was composed of glucose,mannose,and galactose at a molar ratio of 67.62:14.07:7.50,and the weightaverage molecular weights were 5.439×10^(6) and 1.704×10^(5) g/mol by using high-performance gel-permeation chromatography-multiple angle laser scatter(HPGPC-MALS)analysis.GAMPS(0.2μg/μL)showed the strongest proliferation ability to THP-1 cells,with cell survival rate of 178.7%.The wound healing effect of GAMPS(0.1μg/μL)was obvious on NIH/3T3 and 3.75μg/μL of GAMPS showed the strongest total antioxidant ability.All the results indicate that GAMPS promotes cell proliferation,and has cell wound healing effect and strong antioxidant activity.The results provide theoretical foundation for the development and utilization of GAMPS. | Shuangzhi Zhao Ming Lei Hui Xu Hailun He Alexander Suvorov Junhua Wang Jiying Qiu Qingxin Zhou Jinyu Yang Leilei Chen | 2021 | Food Science and Human Wellness2021，10，4： | 4 |
| 9 | The temporal and spatial variations in the Pacific wind and wave fields for the period 2002–2011显示文摘The temporal and spatial variations in the wind and wave fields in the Pacific Ocean between 2002 and 2011 are analyzed using a third-generation wave model(WAVEWATCH III). The model performance for a significant wave height is validated using in situ buoy data. The results show that the wave model effectively hindcasts the significant wave height in the Pacific Ocean, but the errors are relatively large in the mid- and low-latitude regions. The spatial distributions and temporal variations in a wind speed and the significant wave height in the Pacific Ocean are then considered after dividing the Pacific Ocean into five regions, which show meridional differences and seasonal cycles. Regional mean values are used to give yearly average time series for each separate zone. The high latitude region in the Southern Hemisphere had a stronger significant wave height trend in the model results than regions at other latitudes. The sources and sinks of wave energy are then investigated. Their regional mean values are used to quantify variations in surface waves. Finally, the spectral analyses of the daily mean wind speeds and the significant wave heights are obtained. The significant wave height and the wind speed spectra are found to be connected in some ways but also show certain differences. | XU Yao BI Fan SONG Jinbao HE Hailun | 2017 | Acta Oceanologica Sinica2017，36，3： | 3 |
| 10 | NOVEL 6-DOF WEARABLE EXOSKELETON ARM WITH PNEUMATIC FORCE-FEEDBACK FOR BILATERAL TELEOPERATION显示文摘A particular emphasis is put on a novel wearable exoskeleton arm,ZJUESA,with 6 degrees of freedom,which is used for the robot teleoperation with the force-feedback in the unknown environment.In this external structure mechanism,the 3-revolution-prismatic-spherical(3RPS) parallel mechanism is devised from the concept of the human upper-limb anatomy and applied for the shoulder 3-DOF joint.Meanwhile,the orthogonal experiment design method is introduced for its optimal design.Aiming at enhancing the performance of teleoperation,the force feedback is employed by the pneumatic system on ZJUESA to produce the vivid feeling in addition to the soft control interface.Due to the compressibility and nonlinearity of the pneumatic force feedback system, a novel hybrid fuzzy controller for the precise force control is proposed and realized based on the Mega8 microcontroller units as the units of the distributed control system on ZJUESA.With the results of several experiments for master-slave control with force feedback,the feasibility of ZJUESA system and the effect of its hybrid fuzzy controller are verified. | ZHANG Jiafan FU Hailun DONG Yiming ZHANG Yu YANG Canjun CHEN Ying | 2008 | Chinese Journal of Mechanical Engineering2008，21，3： | 3 |
| 11 | Large eddy simulation of turbulence in ocean surface boundary layer at Zhangzi Island offshore显示文摘这研究使用调查骚乱的模型在 Zhangzi 在海洋表面边界层处理的大旋涡模拟(LES ) 岛近海。在 Zhangzi 岛的领域大小(39 ?? 桴?? | LI Shuang SONG Jinba HE Hailun HUANG Yansong | 2013 | Acta Oceanologica Sinica2013，32，7： | 2 |
| 12 | Best Effort Spectrum Allocation Scheme for Femtocell Networks in Dense Deployment显示文摘In orthogonal frequency division multiple access(OFDMA) based femtocell networks,the co-tier interference among femto base stations(FBS) becomes important in multiuser and densely deployed environment.In order to mitigate the co-tier interference and enhance the system total throughput,this paper proposed a best effort spectrum allocation scheme based on the extension of graph theory.In the scheme,a controller was proposed to collect the channel state information(CSI)of all femtocell user equipments(FUEs) in a certain range.Then,the controller evaluated the signal-to-interference Ratio(SIR) of each FUE and determined the set of its interference neighbors.By calculating the received power matrix(RPM) among FUEs and building interference graph matrix(IGM),different spectrum resource blocks(RBs) were assigned to the users with interference relation,while users without interference relation shared the same RBs,which could increase the spectrum efficiency.Simulation results show that the proposed algorithm can significantly improve the RB usage efficiency compared with the basic graph coloring theory,and more than 80% improvement can be acquired in dense deployment scenario.Besides,the throughput of both cell edge macro user equipments(MUEs) and cell edge FUEs is guaranteed on the premise of low interference. | XIA Hailun ZHAO Yan ZENG Zhimin | 2014 | China Communications2014，11，8： | 2 |
| 13 | Analysis of the nonlinear dynamic response of a rotor supported on ball bearings with floating-ring squeeze film dampers显示文摘 | ZHOU Hailun LUO Guihuo CHEN Guo | 2013 | Mechanism and Machine Theory2013，59，： | 1 |
| 14 | Molecular analysis of the gene encoding a cold-adapted halophilic subtilase from deep-sea psychrotolerant bacterium Pseudoalteromonas sp. SM9913: cloning, expression, characterization and function analysis of the C-terminal PPC domains显示文摘 | Bing-Qiang Yan Xiu-Lan Chen Xiao-Yan Hou Hailun He Bai-Cheng Zhou Yu-Zhong Zhang | 2009 | Extremophiles2009，，4： | 1 |
| 15 | Two dy- namic models of dual clearance squeeze film damper and their verification 显示文摘 | ZHOU Hailun LUO Guihuo CHEN Guo | 2013 | Tribology International2013，66，： | 1 |
| 16 | High throughput and rapid screening of marine protein hydrolysates enriched in peptides with art- giotensin-I-converting enzyme inhibitory activity by capillary electrophoresis显示文摘 | HE Hailun CHEN Xiulan WU Hao | 2007 | Bioresource Technology2007，98，： | 1 |
| 17 | Neonatal jaun- dice is a risk factor for childhood asthma: a retrospective co- hort study 显示文摘 | MinSho Ku HaiLun Sun JiNan Sheu | 2012 | Pediatric allergy and immunology2012，23，7： | 1 |
| 18 | Taste improvement of refrigerated meat treated with cold- adapted protease 显示文摘 | He Hailun Chen Xiulan Li Jianwei | 2004 | Food Chemistry2004，84，2： | 1 |
| 19 | High-Entropy Alloys to Activate the Sulfur Cathode for Lithium-Sulfur Batteries显示文摘Sulfur element possesses an ultrahigh theoretical specific capacity,while the utilization of sulfur in the whole cathode is lower obviously owing to the sluggish kinetics of sulfur and discharged products,limiting the enhancement on energy density of lithium-sulfur batteries.Herein,for the first time,Fe_(0.24)Co_(0.26)Ni_(0.10)Cu_(0.15)Mn_(0.25)high-entropy alloy is introduced as the core catalytic host to activate the electrochemical performance of the sulfur cathode for lithium-sulfur batteries.It is manifested that Fe_(0.24)Co_(0.26)Ni_(0.10)Cu_(0.15)Mn_(0.25)high-entropy alloy nanocrystallites distributed on nitrogen-doped carbon exhibit high electrocatalytic activity toward the conversion of solid sulfur to solid discharged products across soluble intermediate lithium polysulfides.In particular,benefiting from the accelerated kinetics by high-entropy alloy nanocrystallites and synergistic adsorption by nitrogen-doped carbon,the cathode exhibits high reversible capacity of 1079.5 mAh g_(-cathode)^(-1)(high utilization of 89.4%)with the whole cathode as active material,instead of sulfur element.Moreover,under both lean electrolyte(3μmg^(-1))and ultrahigh sulfur loading(27.0 mg cm^(-2))condition,the high discharge capacity of 868.2 mAh g_(-cathode)^(-1)can be still achieved for the sulfur cathode.This strategy opens up a new path to explore catalytic host materials for enhancing the utilization of sulfur in the whole cathode for lithium-sulfur batteries. | Zhenyu Wang Hailun Ge Sheng Liu Guoran Li Xueping Gao | 2023 | Energy & Environmental Materials2023，6，3： | 1 |
| 20 | N-Glycoproteomics Study of Putative N-Glycoprotein Biomarkers of Drug Resistance in MCF-7/ADR Cells显示文摘Currently,drug resistance of anti-cancer therapy has become the main cause of low survival rate and poor prognosis.Full understanding of drug resistance mechanisms is an urgent request for further development of anti-cancer therapy and improve-ment of prognosis.Here we present our N-glycoproteomics study of putative N-glycoprotein biomarkers of drug resistance in doxorubicin resistance breast cancer cell line michigan cancer foundation-7(MCF-7/ADR)relative to parental michigan cancer foundation-7(MCF-7)cells.Intact N-glycopeptides(IDs)from MCF-7/ADR and MCF-7 cells were enriched with zwitterionic hydrophilic interaction liquid chromatography(ZIC-HILIC),labeled with stable isotopic diethylation(SIDE),and analyzed with C18-RPLC-MS/MS(HCD with stepped normalized collision energies);these IDs were identified with database search engine GPSeeker,and the differentially expressed intact N-glycopeptides(DEGPs)were quantified with GPSeekerQuan.With target-decoy searches and control of spectrum-level FDR≤1%,322 intact N-glycopeptides were identified;these intact N-glycopeptides come from the combination of 249 unique peptide backbones(corresponding to 234 intact N-glycoproteins)and 90 monosaccharide compositions(corresponding to 248 putative N-glycosites).The sequence structures of 165 IDs were confirmed with structure-diagnostic fragment ions.With the criteria of observation at least twice among the three technical replicates,≥1.5-fold change and p value<0.05,20 DEGPs were quantified,where five of them were up-regulated and 15 of them were down-regulated;the corresponding intact N-glycoproteins as putative markers of drug resistance were discussed. | Hailun Yang Feifei Xu Kaijie Xiao Yun Chen Zhixin Tian | 2021 | Phenomics2021，1，6： | 1 |
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