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| 1 | Dynamic downscaling of near-surface air temperature at the basin scale using WRF-a case study in the Heihe River Basin, China显示文摘一般发行量模型(GCM ) 的空间决定太粗糙,不能代表地区性的气候变化在地区性,为许多环境建模和影响评价要求的盆,和本地规模。天气研究和预报模型(WRF ) 是一下一代,充分可压缩,有运行时刻的 Euler 非静水力学的 mesoscale 预报模型静水力学的选择。这个模型在从一公里的规模为 downscaling 天气和气候是有用的到几千公里,并且为导出也为水文学模拟要求的气象学的参数是有用的。这篇论文的目的是验证由中国气象学的管理(CMA ) 车站的每日的观察数据,并且由模仿 5 km/1 h 空气温度的 WRF 时时,在原处,分水岭的数据结盟了遥感勘测试验性的研究工程。每日的确认证明 WRF 模拟与观察数据有好同意;R ^ 啜在 WRF 模拟和每个车站之间的 2 ^ 是超过 0.93;为每个车站的 meanbias 错误(MBE ) 绝对是不到 | Xiaoduo PAN Xin Li Xiaokang SHI Xujun HAN Lihui LUO Liangxu WANG | 2012 | Frontiers of Earth Science2012，6，3： | 24 |
| 2 | Hepatitis B virus X protein modulates the apoptosis of hepatoma cell line induced by TRAIL显示文摘The purpose of this study is to observe the effects of HBx on the apoptosis of hepatoma cells induced by TNF-related apoptosis-inducing ligand (TRAIL) and to study prelimi- nary molecular mechanisms for its effects. In order to set up a model in vitro, BEL7402-HBx cell line, stably expressing HBx mRNA, was established by stable transfection of pcDNA-HBx, which contains HBx gene, into hepatoma cell line BEL7402. Control cell line BEL7402-cDNA3, stably transfected with pcDNA3, was set up simultaneously as a control. Trypan blue exclusion test, caspase 3 activity detection and TUNEL assay were performed to detect the apoptosis of BEL7402, BEL7402-cDNA3, BEL7402-HBx induced by TRAIL. The expression of TRAIL recep- tors in three groups was analyzed by Flow cytometry. In addition, phosphorothioated antisense oligonucleotide against the translation initial region of HBx gene (PS-asODNs/HBx) was used to block the expression of HBx in HepG2.2.15 cells and to further confirm the effects of HBx on TRAIL-induced apoptosis. Trypan blue exclusion test indicated that TRAIL had a dose-dependent cytotoxicity on BEL7402, BEL7402-cDNA3 and BEL7402-HBx cells. Under treatment of the same concentration of TRAIL, BEL7402-HBx had a higher apoptosis rate and a higher level of Caspase 3 activation than BEL7402 and BEL7402-cDNA3. TUENL assay showed that the apoptosis rate of BEL7402-HBx induced by 10 μg/L TRAIL was 41.4%±7.2%, signifi- cantly higher than that of BEL7402 and BEL7402-cDNA3 cells. Blockade of HBx expression in Hep G2.2.15 cells partly inhibited the apoptosis induced by TRAIL. The introduction or blockade of HBx did not change the expression pattern of TRAIL receptors. The present study firstly con- firms the effects of HBx on TRAIL- induced apoptosis from two different points and it is not re- lated with the expression level of TRAIL receptors. This would be useful to further clarify the roles of imbalanced apoptosis in pathogenesis of Hepatitis B and related hepatocellular carcinoma. | LIANG Xiaohong 1 , SUN Wensheng 1 , GAO Lifen 1 , MA Chunhong 1 , HAN Lihui 1 & CHEN Youhai 2 1. Institute of Immunology, Medical School of Shandong University, Jinan 250012, China 2. Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia PA19104, USA | 2005 | Science China(Life Sciences)2005，48，3： | 7 |
| 3 | Dark solitons in WS_2 erbium-doped fiber lasers显示文摘Tungsten disulfide(WS_2) is a type of anisotropic-layered compound and has broadband saturable absorption features as saturable absorbers(SAs). With WS_2-based SAs, dark solitons in erbium-doped fiber(EDF) lasers are first obtained. For the generated dark solitons, the center wavelength is measured to be 1530 nm, and the repetition rate is about 116.5 MHz. A series of optical spectra is exhibited. The electrical signal-to-noise ratio is better than 94 d B.Results in this paper demonstrate that WS_2-based SAs are the promising SAs for generating dark solitons in EDF lasers. | Wenjun Liu Lihui Pang Hainian Han Zhongwei Shen Ming Lei Hao Teng Zhiyi Wei | 2016 | Photonics Research2016，4，3： | 4 |
| 4 | Using an Improved Clustering Method to Detect Anomaly Activities显示文摘In this paper, an improved k-means based clustering method (IKCM) is proposed. By refining the initial cluster centers and adjusting the number of clusters by splitting and merging procedures, it can avoid the algorithm resulting in the situation of locally optimal solution and reduce the number of clusters dependency. The IKCM has been implemented and tested. We perform experiments on KDD-99 data set. The comparison experiments with H-means+also have been conducted. The results obtained in this study are very encouraging. | LI Han ZHANG Nan BAO Lihui | 2006 | Wuhan University Journal of Natural Sciences2006，11，6： | 3 |
| 5 | The air-borne particulate pollution in Beijing—concentration, composition, distribution and sources显示文摘 | Yele Sun Guoshun Zhuang Ying Wang Lihui Han Jinghua Guo Mo Dan Wenjie Zhang Zifa Wang Zhengping Hao | 2004 | Atmospheric Environment2004，，35： | 2 |
| 6 | Matrine induces apoptosis of human multiple myeloma cells via activation of the mitochondrial pathway显示文摘 | Han Yixiang Zhang Shenghui Wu Jianbo Yu Kang Zhang Yu Yin Lihui Bi Laixi | 2010 | Leukemia & Lymphoma2010，，7： | 1 |
| 7 | Study on rolling process optimization of high carbon steel wire显示文摘The existing problems in the manufacture of SWRH82B high carbon steel wire were discussed by sampling and testing the microstructure and properties of the steel from the workshop. To solve the problems, the experimental parameters for thermal simula- tion were optimized, and the thermal simulating experiments were carried out on a Gleeble1500 thermal simulator. The process pa- rameters for the manufacture were optimized after analysis of the data, and the productive experiments were performed after the wa- ter box in front of the no-twist blocks was reconstructed, to control the temperature of the loop layer. The results from the productive experiments showed that the cooling rate of 10-15°C/s was reasonable before phase transformation, about 5°C/s during phase trans- formation, and 600-620°C was the suitable starting temperature for phase transformation. The ultimate strength of the φ11.0 mm wire was increased to 1150-1170 MPa with an increase of 20-30 MPa, the percentage reduction of section was to 34%-36% with an increase of 1%-3% by testing the finished products after reconstruction. | Yu-An Jing Lin Hu Lihui Wang Jingtao Han | 2007 | Journal of University of Science and Technology Beijing2007，14，5： | 1 |
| 8 | Temporal-spatial distributions of road silt loadings and fugitive road dust emissions in Beijing from 2019 to 2020显示文摘Road silt loading(sL)is an important parameter in the fugitive road dust(FRD)emissions.In this study,the improved Testing Re-entrained Aerosol Kinetic Emissions from Roads(TRAKER)combined with the AP-42 method was firstly developed to quickly measure and estimate the sLs of paved roads in Beijing,China.The annual average sLs in Beijing was 0.59±0.31 g/m^(2)in 2020,and decreased by 22.4%compared with that in 2019.The seasonal variations of sLs followed the order of spring>winter>summer>autumn in the two years.The seasonal mean road sLs on the same type road in the four seasons presented a decline trend from^(2)019 to 2020,especially on the Expressway,decreasing 47.4%-72.7%.The road sLs on the different type roads in the same season followed the order of Major arterial∼Minor arterial∼Branch road>Express road,and Township road∼Country highway>Provincial highway∼National highway.The emission intensities of PM10 and PM_(2.5)from FRD in Beijing in 2020 were lower than those in 2019.The PM10 and PM_(2.5)emission intensities at the four planning areas in the two years all presented the order of the capital functional core area>the urban functional expansion area>the urban development new area>the ecological conservation and development area.The annual emissions of PM10 and PM_(2.5)from FRD in Beijing in 2020 were 74,886 ton and 18,118 ton,respectively,decreasing by∼33.3%compared with those in 2019. | Haibin Wang Lihui Han Tingting Li Song Qu Yuncheng Zhao Shoubin Fan Tong Chen Haoran Cui Junfang Liu | 2023 | Journal of Environmental Sciences2023，，10： | 1 |
| 9 | High Q multilayer spiral inductor on silicon chip for 5-6 GHz显示文摘 | Lihui G Mingbin Y Zhen C Han H Yi Z | 2002 | IEEE Electron Device Lett2002，23，8： | 1 |
| 10 | The mineral aerosol and its impact on urban pollution aerosols over Beijing, China显示文摘 | Lihui Han Guoshun Zhuang Shuiyuan Cheng Juan Li | 2007 | Atmospheric Environment2007，，35： | 1 |
| 11 | Direct electrochemistry of hemoglobin immobilized on siliceous mesostructured cellular foam显示文摘 | LI Jinxia ZHOU Lihui HAN Xia | 2009 | Sensor Actuat B2009，138，： | 1 |
| 12 | Characteristics of re-suspended road dust and its impact on the atomspheric environment in Beijing显示文摘 | Han Lihui Zhuang Guoshun Cheng Shuiyuan | 2007 | Atomspheric Environment2007，，41： | 1 |
| 13 | Development of P genome-specific SNPs and their application in tracing Agropyron cristatum introgressions in common wheat显示文摘As an important wild relative of wheat, Agropyron cristatum has been successfully used for wheat improvement. Currently, a few useful agronomic traits of A. cristatum, such as high grain number per spike and resistance to diseases, have been transferred into common wheat.However, the effective detection of small A. cristatum segmental introgressions in common wheat is still difficult. The objective of this study was to identify A. cristatum-specific single nucleotide polymorphisms(SNPs) for the detection of small alien segments in wheat. The transcriptome sequences of A. cristatum were aligned against wheat coding DNA sequences(CDS) for SNP calling. As a result, we discovered a total of 167,613 putative SNPs specific to the P genome of A. cristatum compared with the common wheat genomes. Among 230 selected SNPs with functional annotations related to inflorescence development and stress resistance,68 were validated as P genome-specific SNPs in multiple wheat backgrounds using Kompetitive Allele Specific PCR(KASP) assays. Among them, 55 SNPs were assigned to six homoeologous groups of the P genome using wheat-A. cristatum addition lines, and 6 P-specific SNP markers were further physically mapped on different segments of chromosome 6 P in 6 P translocation lines. The P genome-specific SNPs were also validated by Sanger sequencing and used to detect the P chromatin in wheat-A. cristatum cryptic introgression lines. Two SNP markers(Unigene20217-182 and Unigene20307-1420) were detected in two wheat-A. cristatum introgression lines that showed enhanced grain number per spike and high resistance to powdery mildew. Together, the developed P genome-specific SNP markers will accelerate the detection of large numbers of wheat-A. cristatum derivatives and will be helpful for marker-assisted transfer of desirable traits from A. cristatum into adapted wheat cultivars in wheat breeding programs. | Huihui Ma Jinpeng Zhang Jing Zhang Shenghui Zhou Haiming Han Weihua Liu Xinming Yang Xiuquan Li Lihui Li | 2019 | The Crop Journal2019，7，2： | 1 |
| 14 | The complex morphologies of Ti -MCM -41 templated by Gemini surfactant显示文摘 | Jun Hu Lihui Zhou Xia Han | 2007 | Materials Research Bulletin2007，，42： | 1 |
| 15 | The air-borne particulate pollution in Beijing—concentration, composition, distribution and sources显示文摘 | Yele Sun Guoshun Zhuang Ying Wang Lihui Han Jinghua Guo Mo Dan Wenjie Zhang Zifa Wang Zhengping Hao | 2004 | Atmospheric Environment2004，，35： | 1 |
| 16 | The complex morphologies of Ti--MCM--41 templated by Gemini surfactant显示文摘 | Hu Jun Zhou Lihui Han Xia etal | 2007 | Materials Research Bulletin2007，，42： | 1 |
| 17 | Application of graphene for preconcentration and highly sensitive stripping voltammetric analysis of organophosphate pesticide显示文摘 | Shuo Wu Xiaoqin Lan Lijun Cui Lihui Zhang Shengyang Tao Hainan Wang Mei Han Zhiguang Liu Changgong Meng | 2011 | Analytica Chimica Acta2011，，2： | 1 |
| 18 | EUV-dependence of Venusian dayside ionopause altitude:VEX and PVO observations显示文摘The Venusian dayside ionosphere, similar to other planetary ionospheres, is produced primarily by ionization of its neutral upper atmosphere due to solar extreme ultraviolet (EUV) radiation. It has become clear that the expansion of the ionosphere may be strongly controlled by the EUV level, as exhibited in data collected by the Pioneer Venus Orbiter (PVO) during one solar cycle (1978 1992). However, the EUV-dependence of the Venusian dayside ionopause altitude, which defines the outer boundary of the ionosphere, remains obscure because the PVO crossed the dayside ionopause only during the solar maximum;its periapsis lifted too high during the solar minimum. Recently, during the period 2006 2014, which included the longest and quietest solar minimum of the past several decades, Venus Express (VEX) provided measurements of the photoelectron boundary (PEB) over the northern high-latitude region. Since the photoelectron boundary is closely related to the ionopause, we have an opportunity to analyze the EUV effect on the dayside ionopause by combining PVO and VEX observations. We have evaluated and then reduced the orbit bias effect in data from both PVO and VEX, and then used the results to derive a relationship between solar EUV level and the dayside ionopause altitude. We find that the dayside ionopause altitude increases as the solar EUV level increases, which is consistent with theoretical expectations. | QianQian Han Markus Fraenz Yong Wei Eduard Dubinin Jun Cui LiHui Chai ZhaoJin Rong WeiXing Wan Yoshifumi Futaana | 2020 | Earth and Planetary Physics2020，4，1： | 1 |
| 19 | Reduced graphene oxide/ PAMAM - silver nanoparticles nanocomposite modified electrode for direct electrochemistry of glucose oxidase and glucose sensing 显示文摘 | Zhimin Luo Lihui Yuwen Ytijie Han | 2012 | Biosensors and Bioelectronics2012，36，： | 1 |
| 20 | Introgression of chromosome 6PL terminal segment from Agropyron cristatum to increase both grain number and grain weight in wheat显示文摘Agropyron cristatum(2n=4x=28,PPPP),which harbours many high-yield and disease-resistance genes,is a promising donor for wheat improvement.Narrow genetic diversity and the trade-off between grain weight and grain number have become bottlenecks for increasing grain yield in wheat.In this study,a novel translocation line,WAT650l,was derived from the chromosome 6P addition line 4844–12,which can simultaneously increase both grain number per spike(GNS)and thousand-grain weight(TGW).Cytological analysis and molecular marker analysis revealed that WAT650l was a 5BL.5BS-6PL(bin 12–17)translocation line.Assessment of agronomic traits and analysis of the BC4F2 and BC5F2 populations suggested that the 6PL terminal chromosome segment in WAT650l resulted in increased grain number per spike(average increased by 14.07 grains),thousand-grain weight(average increased by 4.31 g),flag leaf length,plant height,spikelet number per spike and kernel number per spikelet during the two growing seasons of 2020–2021 and 2021–2022.Additionally,the increased GNS locus and high-TGW locus of WAT650l were mapped to the bins 16–17 and 12–13,respectively,on chromosome 6PL by genetic population analysis of three translocation lines.In summary,we provide a valuable germplasm resource for broadening the genetic base of wheat and overcoming the negative relationship between GNS and TGW in wheat breeding. | Yida Lin Shenghui Zhou Xuezhong Liang Bing Han Junli Yang Baojin Guo Jinpeng Zhang Haiming Han Weihua Liu Xinming Yang Xiuquan Li Lihui Li | 2023 | The Crop Journal2023，11，3： | 1 |
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