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| 1 | A Model Output Machine Learning Method for Grid Temperature Forecasts in the Beijing Area显示文摘In this paper, the model output machine learning (MOML) method is proposed for simulating weather consultation, which can improve the forecast results of numerical weather prediction (NWP). During weather consultation, the forecasters obtain the final results by combining the observations with the NWP results and giving opinions based on their experience. It is obvious that using a suitable post-processing algorithm for simulating weather consultation is an interesting and important topic. MOML is a post-processing method based on machine learning, which matches NWP forecasts against observations through a regression function. By adopting different feature engineering of datasets and training periods, the observational and model data can be processed into the corresponding training set and test set. The MOML regression function uses an existing machine learning algorithm with the processed dataset to revise the output of NWP models combined with the observations, so as to improve the results of weather forecasts. To test the new approach for grid temperature forecasts, the 2-m surface air temperature in the Beijing area from the ECMWF model is used. MOML with different feature engineering is compared against the ECMWF model and modified model output statistics (MOS) method. MOML shows a better numerical performance than the ECMWF model and MOS, especially for winter. The results of MOML with a linear algorithm, running training period, and dataset using spatial interpolation ideas, are better than others when the forecast time is within a few days. The results of MOML with the Random Forest algorithm, year-round training period, and dataset containing surrounding gridpoint information, are better when the forecast time is longer. | Haochen LI Chen YU Jiangjiang XIA Yingchun WANG Jiang ZHU Pingwen ZHANG | 2019 | Advances in Atmospheric Sciences2019，36，10： | 9 |
| 2 | Machine Learning−based Weather Support for the 2022 Winter Olympics显示文摘1.A key support for the 2022 Winter Olympics The XXIV Olympic Winter Games are scheduled to take place from 4 to 22 February 2022,followed by the Paralympic Games from 4 to 13 March,in Beijing and towns in the neighboring Hebei Province,China.Weather plays an extremely important role in the outcome of the games(Chen et al.,2018).It can not only cause a difference between a medal or not,but affect the safety of athletes.Success of the Winter Olympics will greatly depend on weather conditions at the outdoor competition venues,dealing with many weather elements including the snow surface temperature,apparent temperature,gust wind speed,snow,visibility,etc.To ensure that the scheduled games go smoothly,it is imperative to have hourly or even every 10-minutely forecasts as well as updated weather-related risk assessments at the venues for the next 240 hours.So far,the Beijing/Hebei Meteorological Observatory has already started intelligent weather forecasting at 3-km resolution based on the results of numerical weather prediction(NWP)models.However,these experiments have suggested that the current forecasting techniques are incapable of capturing the complex mountain weather variations around some venues.The forecasting capability of NWP is constrained partly by limited knowledge of the local weather mechanisms. | Jiangjiang XIA Haochen LI Yanyan KANG Chen YU Lei JI Lve WU Xiao LOU Guangxiang ZHU Zaiwen Wang Zhongwei YAN Lizhi WANG Jiang ZHU Pingwen ZHANG Min CHEN Yingxin ZHANG Lihao GAO Jiarui HAN | 2020 | Advances in Atmospheric Sciences2020，37，9： | 6 |
| 3 | A 10×10 deep ultraviolet light-emitting micro-LED array显示文摘In this work,we design and fabricate a deep ultraviolet(DUV)light-emitting array consisting of 10×10 micro-LEDs(μ-LEDs)with each device having 20μm in diameter.Strikingly,the array demonstrates a significant enhancement of total light output power by nearly 52%at the injection current of 100 mA,in comparison to a conventional large LED chip whose emitting area is the same as the array.A much higher(~22%)peak external quantum efficiency,as well as a smaller efficiency droop forμ-LED array,was also achieved.The numerical calculation reveals that the performance boost can be attributed to the higher light extraction efficiency at the edge of eachμ-LED.Additionally,the far-field pattern measurement shows that theμ-LED array possesses a better forward directionality of emission.These findings shed light on the enhancement of the DUV LEDs performance and provide new insights in controlling the light behavior of theμ-LEDs. | Huabin Yu Muhammad Hunain Memon Hongfeng Jia Haochen Zhang Meng Tian Shi Fang Danhao Wang Yang Kang Shudan Xiao Shibing Long Haiding Sun | 2022 | Journal of Semiconductors2022，43，6： | 3 |
| 4 | Sodium tungsten bronze(Na_(x)WO_(3))-doped near-infrared-shielding bulk glasses for energy-saving applications显示文摘Tungsten bronze coatings and films have attracted global attention for their applications in near-infrared(NIR)-shielding windows.However,they are unstable in strong ultraviolet,humid heat,alkaline and/or oxidizing environments and are difficult to be coated on glass surfaces with complex shape.Here,we address these limitations by doping sodium tungsten bronze(Na_(x)WO_(3))into bulk glasses using a simple glass melting method.X-ray diffraction,Raman spectroscopy,X-ray photoelectron spectroscopy,TEM and SEM-EDS characterization confirmed the presence of sodium tungsten bronze(Na_(x)WO_(3))functional units inside the 34SiO_(2)-38B_(2)O_(3)-28NaF glass matrix.Because the functional units are well protected by the glass matrix,the fabricated glasses are stable under hot,humid,oxidizing conditions,as well as under ambient conditions,with no change after 360 days.The NIR-shielding performance of these glasses can be adjusted to as high as 100%by varying WO_(x)concentration(2-8 mol%)and quenching temperature(1000-1400℃).With a content of 6 mol%WO_(x)and a quenching temperature of 1000℃,the bulk glass shows 63%transmission of visible light and only 11%transmission of NIR light at 1100 nm.Thermal insulation experiments show that the NIR-shielding performance of the glasses are far superior to commercial soda lime window glass or indium-doped tin oxide(ITO)glass,and comparable to cesium tungsten bronze coated glass.The novel bulk glasses have higher stability,simpler processing,and can be easily made into complex shapes,making them excellent alternative materials for energy-saving glasses. | Guang Yang Yunhang Qi Daming Hu Haochen Wang Hongfei Chen Liangmiao Zhang Chuanxiang Cao Bin Liu Fang Xia Yanfeng Gao | 2021 | Journal of Materials Science & Technology2021，，30： | 3 |
| 5 | Hippo-YAP/TAZ signaling in osteogenesis and macrophage polarization:Therapeutic implications in bone defect repair显示文摘Bone defects caused by diseases or surgery are a common clinical problem.Researchers are devoted to finding biological mechanisms that accelerate bone defect repair,which is a complex and continuous process controlled by many factors.As members of transcriptional costimulatory molecules,Yes-associated protein(YAP)and transcriptional co-activator with PDZ-binding motif(TAZ)play an important regulatory role in osteogenesis,and they affect cell function by regulating the expression of osteogenic genes in osteogenesis-related cells.Macrophages are an important group of cells whose function is regulated by YAP/TAZ.Currently,the relationship between YAP/TAZ and macrophage polarization has attracted increasing attention.In bone tissue,YAP/TAZ can realize diverse osteogenic regulation by mediating macrophage polarization.Macrophages polarize into M1 and M2 phenotypes under different stimuli.M1 macrophages dominate the inflammatory response by releasing a number of inflammatory mediators in the early phase of bone defect repair,while massive aggregation of M2 macrophages is beneficial for inflammation resolution and tissue repair,as they secrete many anti-inflammatory and osteogenesis-related cytokines.The mechanism of YAP/TAZ-mediated macrophage polarization during osteogenesis warrants further study and it is likely to be a promising strategy for bone defect repair.In this article,we review the effect of Hippo-YAP/TAZ signaling and macrophage polarization on bone defect repair,and highlight the regulation of macrophage polarization by YAP/TAZ. | Haochen Wang Hui Yu Tianyu Huang Bin Wang Lin Xiang | 2023 | Genes & Diseases2023，10，6： | 2 |
| 6 | A reactive oxygen species-responsive hydrogel encapsulated with bone marrow derived stem cells promotes repair and regeneration of spinal cord injury显示文摘Spinal cord injury(SCI)is an overwhelming and incurable disabling event accompanied by complicated inflammation-related pathological processes,such as excessive reactive oxygen species(ROS)produced by the infiltrated inflammatory immune cells and released to the extracellular microenvironment,leading to the widespread apoptosis of the neuron cells,glial and oligodendroctyes.In this study,a thioketal-containing and ROS-scavenging hydrogel was prepared for encapsulation of the bone marrow derived mesenchymal stem cells(BMSCs),which promoted the neurogenesis and axon regeneration by scavenging the overproduced ROS and re-building a regenerative microenvironment.The hydrogel could effectively encapsulate BMSCs,and played a remarkable neuroprotective role in vivo by reducing the production of endogenous ROS,attenuating ROS-mediated oxidative damage and downregulating the inflammatory cytokines such as interleukin-1 beta(IL-1β),interleukin-6(IL-6)and tumor necrosis factor-alpha(TNF-α),resulting in a reduced cell apoptosis in the spinal cord tissue.The BMSCs-encapsulated ROS-scavenging hydrogel also reduced the scar formation,and improved the neurogenesis of the spinal cord tissue,and thus distinctly enhanced the motor functional recovery of SCI rats.Our work provides a combinational strategy against ROS-mediated oxidative stress,with potential applications not only in SCI,but also in other central nervous system diseases with similar pathological conditions. | Ziming Li Tengfei Zhao Jie Ding Haochen Gu Qiaoxuan Wang Yifan Wang Deteng Zhang Changyou Gao | 2023 | Bioactive Materials2023，，1： | 2 |
| 7 | Optimization Scheme of Large Passenger Flow in Huoying Station,Line 13 of Beijing Subway System显示文摘This paper focuses on the distribution of passenger flow in Huoying Station,Line 13 of Beijing subway system.The transformation measures taken by Line 13 since operation are firstly summarized.Then the authors elaborate the facilities and equipment of this station,especially the node layout and passenger flow field.An optimization scheme is proposed to rapidly distribute the passenger flow in Huoying Station by adjusting the operation time of the escalator in the direction of Xizhimen.The authors adopt Queuing theory and Anylogic simulation software to simulate the original and the optimized schemes of Huoying Station to distribute the passenger flow.The results of the simulation indicate that the optimized scheme could effectively alleviate the traffic congestion in the hall of Huoying Station,and the pedestrian density in other places of the hall is lowered;passengers could move freely in the hall and no new congestion points would form.The rationality of the scheme is thus proved. | Jin Zhou Haochen Wang Di Sun Siqiang Xu Meng Lv Feifei Yu | 2020 | Computers, Materials & Continua2020，，6： | 2 |
| 8 | Caspase‐3 Modulates Regenerative Response After Stroke显示文摘 | Wenying Fan Yiqin Dai Haochen Xu Ximin Zhu Ping Cai Lixiang Wang Chungang Sun Changlong Hu Ping Zheng Bing‐Qiao Zhao | 2014 | Stem Cells2014，，2： | 1 |
| 9 | Lysohexaenetides A and B,linear lipopeptides from Lysobacter sp.DSM 3655 identified by heterologous expression in Streptomyces显示文摘Lysobacter harbors a plethora of cryptic biosynthetic gene clusters(BGCs),albeit only a limited number have been analyzed to date.In this study,we described the activation of a cryptic polyketide synthase(PKS)/nonribosomal peptide synthetase(NRPS)gene cluster(lsh)in Lysobacter sp.DSM 3655 through promoter engineering and heterologous expression in Streptomyces sp.S001.As a result of this methodology,we were able to isolate two novel linear lipopeptides,lysohexaenetides A(1)and B(2),from the recombinant strain S001-lsh.Furthermore,we proposed the biosynthetic pathway for lysohexaenetides and identified LshA as another example of entirely iterative bacterial PKSs.This study highlights the potential of heterologous expression systems in uncovering cryptic biosynthetic pathways in Lysobacter genomes,particularly in the absence of genetic manipulation tools. | XU Qiushuang ZOU Haochen PAN Chen WANG Haoxin SHEN Yuemao LI Yaoyao | 2023 | Chinese Journal of Natural Medicines2023，21，6： | 1 |
| 10 | A SIXTH ORDER AVERAGED VECTOR FIELD METHOD显示文摘在这份报纸,基于生根的树和 B 系列的理论,我们为顺序 = 的树建议替换法律的具体公式 5。在新替换法律的帮助下,我们导出扩大平均向量地(AVF ) 方法让一般 Hamiltonian 系统更高订的一个 B 系列综合者。新综合者结果是六的顺序并且确切为 Hamiltonian 系统保存精力。数字实验被介绍表明精确性和第六个顺序 AVF 方法的保存精力的性质。[从作者抽象] | Haochen Li Yushun Wang Mengzhao Qin | 2016 | Journal of Computational Mathematics2016，34，5： | 1 |
| 11 | Design of a knowledge-based performance evaluation system: a case of high-tech state-owned enterprises in an emerging economy 显示文摘 | Wang Weikang Huang Haochen Lai Meichi | 2008 | Expert Systems with Applications2008，34，： | 1 |
| 12 | Evaluation of allergenic protein profiles in three Chinese high-oleic acid peanut cultivars using NanoLC-Orbitrap mass spectrometry显示文摘High oleic-acid peanuts are known for their pre-longed shelf-life and health benefit due to high content of oleic fatty acid.However,the allergenicity and allergenic protein profiles in Chinese high-oleic peanuts have yet to be studied.For this purpose,an Orbitrap Fusion mass spectrometry(MS)-based method that is feasible for identification of putative allergenic protein as well as semi-quantitation of five major allergen protein in three different Chinese high-oleic peanut cultivars(JH 13,JH 16 and JH 18)have been reported.Results show that three Chinese high-oleic acid peanut cultivars selected all contained highly allergenic proteins Ara h1,Ara h 2,Ara h 3 and Ara h 6.The allergenic protein profiles of Chinese high-oleic acid peanut cultivars were very similar to that of conventional peanuts,but the allergenic protein subunits varied greatly among higholeic peanuts.Additionally,a comprehensive peptide-filtering pipeline had been developed for identification of potential peptide markers in peanut allergen proteins.Through the peptide-filtering pipeline,three novel peptide markers,IVQIEAKPNTLVLPK,SSNPDIYNPQAGSLR and AQSENYEYLAFK surrogate to Ara h 1,Ara h 3 with high abundance,good MS response and highly reliability were identified,which can be used as candidate peptide markers for the detection of peanut allergens in different food matrices. | Xinke Yang Haochen Bai Lijun Yin Jin Wang Wentong Xue Xin Jia | 2023 | Food Science and Human Wellness2023，12，3： | 1 |
| 13 | Effect of calcination temperature on the pozzolanic activity of maize straw stem ash treated with portlandite solution显示文摘The effect of calcination temperature on the pozzolanic activity of maize straw stem ash(MSSA)was evaluated.The MSSA samples calcined at temperature values of 500,700,and 850℃ were dissolved in portlandite solution for 6 h,thereby obtaining residual samples.The MSSA and MSSA residual samples were analyzed using Fourier transform infrared spectroscopy,X-ray powder diffraction scanning electron microscopy,and X-ray photoelectron spectroscopy to determine vibration bonds,minerals,microstructures,and Si 2p transformation behavior.The conductivity,pH value,and loss of conductivity with dissolving time of the MSSA-portlandite mixed solution were also determined.The main oxide composition of MSSA was silica and potassium oxide.The dissolution of the Si^(4+) content of MSSA at 500℃ was higher than those of the other calcination temperatures.The conductivity and loss of conductivity of MSSA at 700℃ were higher than those of the other calcination temperatures at a particular dissolving time due to the higher KCl content in MSSA at 700℃.C-S-H was easily identified in MSSA samples using X-ray powder diffraction,and small cubic and nearly spherical particles of C-S-H were found in the MSSA residual samples.In conclusion,the optimum calcination temperature of MSSA having the best pozzolanic activity is 500℃,but excessive agglomeration must be prevented. | Tingye Qi Haochen Wang Guorui Feng Yujiang Zhang Jinwen Bai Yanna Han | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，6： | 0 |
| 14 | Modeling and Experimental Evaluation of a Bionic Soft Pneumatic Gripper with Joint Actuator显示文摘The pneumatic gripper in industrial applications has the advantages of structure simplicity and great adaptability,but its gripping power is usually limited due to the low modulus of soft materials.To address this problem,a novel bionic pneumatic gripper inspired by spider legs is proposed.The design has two pairs of symmetrical fingers,each finger consists of two pneumatic actuated joints,two rigid links and one pneumatic soft pad.The rigid link connects the pneumatic chamber which is enclosed in a retractable shell to increase the actuation pressure and the gripping force.The compressibility and elasticity of the soft joint and pad enable the gripper to grasp fragile objects without damage.The modeling of the bionic gripper is developed,and the parameters of the joint actuators are optimized accordingly.The prototype is manufactured and tested with the developed experimental platform,where the gripping force,flexibility and adaptability are evaluated.The results indicate that the designed gripper can grasp irregular and fragile items in sizes from 40 to 140 mm without damage,and the lifting weight is up to 15 N. | Ming Ma Quansheng Jiang Haochen Wang Yehu Shen Fengyu Xu | 2023 | Journal of Bionic Engineering2023，20，4： | 0 |
| 15 | Behaviour and mechanisms of molecular vibrations induced by a pulsed voltage in a silicone elastomer used for device encapsulation显示文摘Silicone elastomers are widely used to encapsulate power electronic devices.However,such devices may be subjected to square‐wave pulsed voltages with a high rate of change,which can create significant challenges for encapsulation insulation.In this article,the molecular vibration of silicon elastomer at the edge of pulsed electric field is studied.Firstly,the relationship between the intensity of molecular vibration and the parameters of pulsed electric field is explored.The experimental results show that the amplitude of the vibrations decreases as the pulse‐edge time increases,and it increases linearly as the pulseedge slope increases.Furthermore,the amplitude of the vibrations is proportional to the square of the amplitude of the pulsed electric field,and it increases as the space charge density increases.Then,the force analysis of charged molecule at the pulse edges is calculated,and the theoretical change law of molecular vibration intensity with pulse edge slope is deduced.Comparing the theoretical results with the experimental results,it is found that they are highly consistent.Finally,electrically induced mechanical stress caused by molecular vibration was shown to be an important factor in insulation failure. | Junyu Wei Dongxin He Teng Gao Lin Zhu Haochen Wang Qingquan Li Gilbert Teyssedre | 2023 | High Voltage2023，8，5： | 0 |
| 16 | Research on the Impacts of the Inertia and Droop Control Gains from a Variable-Speed Wind Turbine Generator on the Frequency Response显示文摘System frequency must be kept very close to its nominal range to ensure the stability of an electric power grid.Excessive system frequency variations are able to result in load shedding,frequency instability,and even generator damage.With increasing wind power penetration,there is rising concern about the reduction in inertia response and primary frequency control in the electric power grid.Converter-based wind generation is capable of providing inertia response and primary frequency response;nevertheless,the primary frequency and inertia responses of wind generation are different from those of conventional synchronous fleets;it is not completely understood how the primary frequency and inertia responses affect the given system under various disturbances and available kinetic energy levels.Simulations are used to investigate the influences of inertia and droop control strategies on the dynamic frequency responses,particularly the index of the second frequency drop under various disturbance and wind conditions.A quantitative analysis provides insight into setting of inertia and droop control coefficients for various wind and disturbance conditions to facilitate adequate dynamic frequency responses during frequency events. | Dejian Yang Yien Xu Tong Zhu Yang Wang Qiuhan Cao Yuang Ma Enshu Jin Xinsong Zhang Haochen Sun | 2022 | Energy Engineering2022，119，2： | 0 |
| 17 | Enhancement of T cell infiltration via tumor-targeted Th9 cell delivery improves the efficacy of antitumor immunotherapy of solid tumors显示文摘Insufficient infiltration of T cells severely compromises the antitumor efficacy of adoptive cell therapy(ACT)against solid tumors.Here,we present a facile immune cell surface engineering strategy aiming to substantially enhance the anti-tumor efficacy of Th9-mediated ACT by rapidly identifying tumor-specific binding ligands and improving the infiltration of infused cells into solid tumors.Non-genetic decoration of Th9 cells with tumor-targeting peptide screened from phage display not only allowed precise targeted ACT against highly heterogeneous solid tumors but also substantially enhanced infiltration of CD8+T cells,which led to improved antitumor outcomes.Mechanistically,infusion of Th9 cells modified with tumor-specific binding ligands facilitated the enhanced distribution of tumor-killing cells and remodeled the immunosuppressive microenvironment of solid tumors via IL-9 mediated immunomodulation.Overall,we presented a simple,cost-effective,and cell-friendly strategy to enhance the efficacy of ACT against solid tumors with the potential to complement the current ACT. | Tao Chen Yucheng Xue Shengdong Wang Jinwei Lu Hao Zhou Wenkan Zhang Zhiyi Zhou Binghao Li Yong Li Zenan Wang Changwei Li Yinwang Eloy Hangxiang Sun Yihang Shen Mohamed Diaty Diarra Chang Ge Xupeng Chai Haochen Mou Peng Lin Xiaohua Yu Zhaoming Ye | 2023 | Bioactive Materials2023，，5： | 0 |
| 18 | Dietary preferences and potential ecological impact on the zooplankton community of Nemopilema nomurai based on stable isotope and fatty acid analyses显示文摘Information on the dietary composition and food preferences of the giant jellyfish Nemopilema nomurai is important for understanding the trophic drivers of jellyfish outbreaks and their ecological consequences.We used fatty acid(FA)and stable isotope(SI)biomarkers to analyze the diet of N.nomurai from the Yellow Sea in August 2016.N.nomurai was found at all sampling stations,with abundances ranging from 59 inds./km^(2) to 1651 inds./km^(2).There were no significant differences between large(>80 cm in diameter)and small(20–30 cm in diameter)medusae,either in FA compositions or in SI values,which suggests that large and small jellyfi sh have the same food composition and similar trophic levels.Compared to other zooplanktons,the relatively high levels of C20꞉4n-6 in total FAs(~12%)indicates that organic detritus contributes considerably to the food composition of the jellyfish.The mixed model Stable Isotope Analysis in R(SIAR)revealed that N.nomurai tended to prey on smaller organisms(<1000μm in diameter)which comprised about 70%of its diet.This means the N.nomurai blooms will put high feeding pressure on the small plankton.The similar SI values and FA composition indicates that krill may share the same food resources with N.nomurai,which suggests that the jellyfi sh blooms may affect krill populations as a result of food competition. | Junjian WANG Chaolun LI Guang YANG Zhencheng TAO Yanqing WANG Haochen XIAN | 2022 | Journal of Oceanology and Limnology2022，40，3： | 0 |
| 19 | The EU Initiative to Levy a Digital-Economy Tax:Potential Effects on China显示文摘The G20 Finance Ministers and Central Bank Governors’Meeting convened on March 19-20,2018 in Buenos Aires,Argentina.“Tax Challenges Arising From Digitalization”(hereinafter referred to as the G20 Report)was published jointly by the Organization for Economic Co-operation and Development(OECD)and G20 after the meeting,and it analyzed the influence of economic digitalization on the international taxation system.This move was hailed as an important step toward the resolution of tax challenges imposed by economic digitalization.As a matter of fact,the European Union(EU)has always been committed to levying tax on companies associated with the digital economy. | WANG Haochen | 2019 | China Economic Transition2019，2，1： | 0 |
| 20 | Navigation in virtual and real environment using brain computer interface:a progress report显示文摘A brain-computer interface (BCI) facilitates bypassing the peripheral nervous system and directly communicating with surrounding devices. Navigation technology using BCI has developed-from exploring the prototype paradigm in the virtual environment (VE) to accurately completing the locomotion intention of the operator in the form of a powered wheelchair or mobile robot in a real environment. This paper summarizes BCI navigation applications that have been used in both real and VEs in the past 20 years. Horizontal comparisons were conducted between various paradigms applied to BCI and their unique signal-processing methods. Owing to the shift in the control mode from synchronous to asynchronous, the development trend of navigation applications in the VE was also reviewed. The contrast between high level commands and low-level commands is introduced as the main line to review the two major applications of BCI navigation in real environments: mobile robots and unmanned aerial vehicles (UAVs). Finally, applications of BCI navigation to scenarios outside the laboratory;research challenges, including human factors in navigation application interaction design;and the feasibility of hybrid BCI for BCI navigation are discussed in detail. | Haochen HU Yue LIU Kang YUE Yongtian WANG | 2022 | Virtual Reality & Intelligent Hardware2022，4，2： | 0 |
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