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| 1 | Polymorphisms in NF-κB,PXR,LXR,PPARγ and risk of inflammatory bowel disease显示文摘AIM:To investigate the contribution of polymorphisms in nuclear receptors to risk of inflammatory bowel disease(IBD) . METHODS:Genotypes of nuclear factor(NF) -κB(NFKB1) NFκB-94ins/del(rs28362491) ;peroxisome proliferatoractivated receptor(PPAR) -γ(PPARγ) PPARγPro12Ala(rs1801282) and C1431T(rs 3856806) ;pregnane X receptor(PXR) (NR1I2) PXR A-24381C(rs1523127) ,C8055T(2276707) ,and A7635G(rs 6785049) ;and liver X receptor(LXR) (NR1H2) LXR T-rs1405655-C and T-rs2695121-C were assessed in a Danish case-control study of 327 Crohn's disease patients,495 ulcerative colitis(UC) patients,and 779 healthy controls.Odds ratio(OR) and 95%CI were estimated by logistic regression models. RESULTS:The PXR A7635G variant,the PPARγPro12Ala and LXR T-rs2695121-C homozygous variant genotypes were associated with risk of UC(OR:1.31,95% CI:1.03-1.66,P=0.03,OR:2.30,95%CI:1.04-5.08,P=0.04,and OR:1.41,95%CI:1.00-1.98,P=0.05,respectively) compared to the corresponding homozygous wild-type genotypes.Among never smokers,PXR A7635G and the LXR T-rs1405655-C and T-rs2695121-C variant genotypes were associated with risk of IBD(OR:1.41,95%CI:1.05-1.91,P=0.02,OR:1.63,95%CI:1.21-2.20,P=0.001,and OR:2.02,95%CI:1.36-2.99,P=0.0005,respectively) compared to the respective homozygous variant genotypes.PXR A7635G(rs6785049) variant genotype was associated with a higher risk of UC diagnosis before the age of 40 years and with a higher risk of extensive disease(OR:1.34,95%CI:1.03-1.75 and OR:2.49,95%CI:1.24-5.03,respectively) . CONCLUSION:Common PXR and LXR polymorphisms may contribute to risk of IBD,especially among never smokers. | Vibeke Andersen Jane Christensen Anja Ernst Bent A Jacobsen Anne Tjφnneland Henrik B Krarup Ulla Vogel | 2011 | World Journal of Gastroenterology2011，17，2： | 4 |
| 2 | A Reverse J-Shaped Association Between Serum 25-Hydroxyvitamin D and Cardiovascular Disease Mortality: The CopD Study显示文摘 | Darshana Durup Henrik L?vendahl J?rgensen Jane Christensen Anne Tj?nneland Anja Olsen Jytte Halkj?r Bent Lind Anne-Marie Heegaard Peter Schwarz | 2015 | The Journal of Clinical Endocrinology & Metabolism2015，，6： | 1 |
| 3 | The value of contrast enhanced ultrasonography in detection of liver metastases from colorectal cancer: A prospective double-blinded study显示文摘 | Lars Peter Skovgaard Larsen Mona Rosenkilde Henrik Christensen Niels Bang Lars Bolvig Thomas Christiansen S?ren Laurberg | 2006 | European Journal of Radiology2006，，2： | 1 |
| 4 | Genetic and Environmental Contributions to Back Pain in Old Age: A Study of 2,108 Danish Twins Aged 70 and Older显示文摘 | Jan Hartvigsen Kaare Christensen Henrik Frederiksen Hans Christian Pedersen | 2004 | Spine2004，，8： | 1 |
| 5 | Behavior coordination in structured environments显示文摘 | Philipp Althaus Henrik I. Christensen | 2003 | Advanced Robotics2003，，7： | 1 |
| 6 | Effects of locally applied vascular endothelial growth factor (VEGF) and VEGF-inhibiter to the rabbit tibia during distraction ostecgenesis显示文摘 | Henrik Eckardt Kristian G Bundgaard Knud S Christensen | 2003 | J Orthop Res2003，21，2： | 1 |
| 7 | Collagen structural organization of healing colonic anastomoses and the effect of growth hormone treatment显示文摘 | Henrik Christensen John Chemnitz Bent Collatz Christensen Hans Oxlund | 1995 | Diseases of the Colon & Rectum1995，，11： | 1 |
| 8 | Benzene exposure and the effect of traffic pollution in Copenhagen, Denmark显示文摘 | Henrik Skov Asger B. Hansen Gitte Lorenzen Helle Vibeke Andersen Per L?fstr?m Carsten S. Christensen | 2001 | Atmospheric Environment2001，，14： | 1 |
| 9 | Chest Pain in Focal Musculoskeletal Disorders显示文摘 | Mette Jensen Stochkendahl Henrik Wulff Christensen | 2010 | Medical Clinics of North America2010，，2： | 1 |
| 10 | Effective Roughness Calculated from Satellite-Derived Land Cover Maps and Hedge-Information used in a Weather Forecasting Model显示文摘 | Charlotte B. Hasager Niels W. Nielsen Niels Otto Jensen Eva Boegh Jens H. Christensen Ebba Dellwik Henrik Soegaard | 2003 | Boundary - Layer Meteorology2003，，3： | 1 |
| 11 | Does neoadjuvant chemotherapy impair long-term survival for ovarian cancer patients? A nationwide Danish study显示文摘 | Carsten Lindberg Fag?-Olsen Bent Ottesen Henrik Kehlet Sofie L. Antonsen Ib J. Christensen Algirdas Markauskas Berit J. Mosgaard Christian Ottosen Charlotte H. Soegaard Erik Soegaard-Andersen Claus Hoegdall | 2013 | Gynecologic Oncology2013，，： | 1 |
| 12 | Development of a multilocus sequence typing (MLST) scheme for Mannheimia haemolytica and assessment of the population structure of isolates obtained from cattle and sheep显示文摘 | Andreas Petersen Henrik Christensen Angéli Kodjo Glen C. Weiser Magne Bisgaard | 2009 | Infection Genetics and Evolution2009，，4： | 1 |
| 13 | Increased Mortality Among Persons Infected With Hepatitis C Virus显示文摘 | Lars Haukali Omland Peter Jepsen Henrik Krarup Kristian Sch?nning Bent Lind Hans Kromann–Andersen Keld Mikkelsen Homburg Peer Brehm Christensen Henrik Toft S?rensen Niels Obel | 2011 | Clinical Gastroenterology and Hepatology2011，，1： | 1 |
| 14 | Collagen structural organization of healing colonic anastomoses and the effect of growth hormone treatment显示文摘 | Dr. Henrik Christensen M.D. John Chemnitz M.D. Bent Collatz Christensen M.D. Hans Oxlund M.D | 1995 | Diseases of the Colon & Rectum1995，，11： | 1 |
| 15 | Diagnostic and typing options for investigating diseases associated with Pasteurella multocida显示文摘 | Francis Dziva Amandus P. Muhairwa Magne Bisgaard Henrik Christensen | 2007 | Veterinary Microbiology2007，，1： | 1 |
| 16 | A method for following unmarked roads显示文摘 | RAMATROM OLA CHRISTENSEN HENRIK | 2005 | IEEE Intelli gent Vehicles Symposium2005，12，9： | 1 |
| 17 | Triangulation-based Fusion of Sonar Data with Application in Robot Pose Tracking 显示文摘 | Olle Wijk Henrik I Christensen | 2000 | IEEE Trans on Robotics and Automation2000，16，6： | 1 |
| 18 | Genetic analysis of Trichuris suis and Trichuris trichiura recovered from humans and pigs in a sympatric setting in Uganda显示文摘 | Sofie Nissen Azmi Al-Jubury Tina V.A. Hansen Annette Olsen Henrik Christensen Stig M. Thamsborg Peter Nejsum | 2012 | Veterinary Parasitology (-)2012，，1： | 1 |
| 19 | Specific identification of Gallibacterium by a PCR using primers targeting the 16S rRNA and 23S rRNA genes显示文摘 | Anders Miki Bojesen Maria Elena Vazquez Fransisco Robles Carlos Gonzalez Edgardo V. Soriano John Elmerdahl Olsen Henrik Christensen | 2007 | Veterinary Microbiology2007，，1： | 1 |
| 20 | Inactivation of OslRX10 Leads to Decreased Xylan Content in Rice Culm Cell Walls and Improved Biomass Saccharification显示文摘Dear Editor, Xylan polysaccharides constitute the major non-cellulosic components in secondary cell walls of dicots and in both primary and secondary cell walls of grasses (Scheller and Ulvskov,2010).Xylan is composed of a linear backbone of 13(1-4)-linked xylose (Xyl).In grasses,the xylan backbone is substituted with O3-1inked and O2-1inked arabinose residues and,to a lesser extent,α(1-3)-Iinked glucuronic acid residues.A unique feature of grass xylans is the presence of hydroxycinnamate esters (ferulic and p-coumaric acid residues)attached to C5 of some of the arabinosyl residues (Carpita,1996;Vogel,2008;Scheller and Ulvskov,2010).Xylan contributes to the recalcitrance of plant cell walls to enzymatic degradation probably through direct interaction with cellulose microfibrils and also through formation of ferulate cross-links (liyama et al.,1994;Yin et al.,2011). | Xuewei Chen Miguel E. Vega-Sanchez Yves Verhertbruggenb Dawn Chiniquy Patrick E. Canlas Alexandra Fagerstrom Lina Prak Ulla Christensen Ai Oikawa Mawsheng Chern Shimin Zuo Fan Lin Manfred Auer William G.T. Willats Laura Bartley Jesper Harholt Henrik V. Scheller Pamela C. Ronald | 2013 | Molecular Plant2013，6，2： | 1 |
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