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| 1 | Clinical utility of the platelet-lymphocyte ratio as a predictor of postoperative complications after radical gastrectomy for clinical T2-4 gastric cancer显示文摘AIM To identify simple and sensitive markers for postoperative complications after gastrectomy, the predictive values were compared among candidate preoperative factors. METHODS Three-hundred and twelve patients with previously untreated clinical T2-4 gastric cancer who underwent a D2 standard gastrectomy(distal gastrectomy or total gastrectomy) were included in the analysis.Correlations between 21 parameters that can be determined by preoperative routine blood tests and clinically relevant postoperative complications(grade Ⅱ or higher according to the Clavien-Dindo classification) were evaluated. The optimal cutoff values and clinical significance of the selected markers were further evaluated by subgroup analyses according to age, body mass index, operative procedure and clinical disease stage.RESULTS Sixty-six patients(21.1%) experienced grade Ⅱ or higher postoperative complications. The plateletlymphocyte ratio(PLR, total lymphocyte count/platelet count × 100) exhibited the highest area under the curve value(0.639) for predicting postoperative complications among the 21 parameters, and the optimal cutoff value was determined to be 0.71(sensitivity = 70%, specificity = 56%). In the univariate analysis, the odds ratio of a low PLR for the occurrence of postoperative complications was 2.94(95%CI: 1.66-5.35, P < 0.001), and a multivariate binomial logistic analysis involving other potential risk factors identified a low PLR as an independent risk factor for postoperative complications(OR = 3.32, 95%CI: 1.82-6.25, P < 0.001). In subgroups classified according to age, body mass index, operative procedure and clinical disease stage, the low PLR group exhibited an increased incidence of postoperative complications. CONCLUSION The preoperative PLR is a simple and useful predictor of complications after curative gastrectomy in patients with clinical T2-4 gastric cancer. | Kenichi Inaoka Mitsuro Kanda Hiroaki Uda Yuri Tanaka Chie Tanaka Daisuke Kobayashi Hideki Takami Naoki Iwata Masamichi Hayashi Yukiko Niwa Suguru Yamada Tsutomu Fujii Hiroyuki Sugimoto Kenta Murotani Michitaka Fujiwara Yasuhiro Kodera | 2017 | World Journal of Gastroenterology2017，23，14： | 13 |
| 2 | Rescue of white egg 1 mutant by introduction of the wildtype Bombyx kynurenine 3-monooxygenase gene显示文摘在蚕,白鸡蛋 1 (w-1 ) 异种,被白眼睛和白鸡蛋描绘,在 Bombyx kynurenine 3-monooxygenase (KMO ) 是缺乏的活动。Toinvestigate w-1 异种显型是否被介绍野类型的 KMO 基因救,我们在细胞质的肌动朊基因倡导者(A3KMO ) 或本国的 KMO 基因倡导者(KKMO ) 的控制下面与野类型的 Bombyx KMO 基因构造了转基因的蚕。我们与 KKMO 构造与 A3KMO 和一根线创造了二根转基因的线。在这些线的成年人的眼睛是棕色的,并且转基因的女性生的鸡蛋也是棕色的。Reversetranscription 聚合酶链反应(RT-PCR ) 分析证明 A3KMO 蚕线在中间勇气的、胖身体表示了抄本,并且肾小体小管。KKMO 线仅仅在胖身体表示了抄本并且肾小体小管。在转基因的线的眼睛和卵色的紧张与 KMO 表示水平成正比。有趣地,有 A3KMO 构造的转基因的幼虫有轻褐幼虫的表皮,而是 KKMO 线不。这些结果显示野类型的 KMO 基因能作为标记基因被使用视觉上屏蔽转基因的蚕。 | GUO-XING QUAN ISAO KOBAYASHI KATSURA KOJIMA KEIRO UCHINO TOSHIO KANDA HIDEKI SEZUTSU TORU SHIMADA TOSHIKI TAMURA | 2007 | Insect Science2007，14，2： | 4 |
| 3 | B?cell translocation gene 1 serves as a novel prognostic indicator ofhepatocellular carcinoma显示文摘 | Mitsuro Kanda Hiroyuki Sugimoto Shuji Nomoto Hisaharu Oya Soki Hibino Dai Shimizu Hideki Takami Ryoji Hashimoto Yukiyasu Okamura Suguru Yamada Tsutomu Fujii Goro Nakayama Masahiko Koike Michitaka Fujiwara Yasuhiro Kodera | 2015 | International Journal of Oncology2015，，2： | 3 |
| 4 | Function and diagnostic value of Anosmin‐1 in gastric cancer progression显示文摘 | Mitsuro Kanda Dai Shimizu Tsutomu Fujii Satoshi Sueoka Yuri Tanaka Kazuhiro Ezaka Hideki Takami Haruyoshi Tanaka Ryoji Hashimoto Naoki Iwata Daisuke Kobayashi Chie Tanaka Suguru Yamada Goro Nakayama Hiroyuki Sugimoto Masahiko Koike Michitaka Fujiwara Yasu | 2016 | Int. J. Cancer2016，，3： | 1 |
| 5 | Translational implication of Kallmann syndrome-1 gene expression inhepatocellular carcinoma显示文摘 | Yuri Tanaka Mitsuro Kanda Hiroyuki Sugimoto Dai Shimizu Satoshi Sueoka Hideki Takami Kazuhiro Ezaka Ryoji Hashimoto Yukiyasu Okamura Naoki Iwata Chie Tanaka Suguru Yamada Tsutomu Fujii Goro Nakayama Masahiko Koike Shuji Nomoto Michitaka Fujiwara Yasuhiro | 2015 | International Journal of Oncology2015，，6： | 1 |
| 6 | Clinical significance of expression and epigenetic profiling of TUSC1 in gastric cancer显示文摘 | Mitsuro Kanda Dai Shimizu Shuji Nomoto Soki Hibino Hisaharu Oya Hideki Takami Daisuke Kobayashi Suguru Yamada Yoshikuni Inokawa Chie Tanaka Tsutomu Fujii Hiroyuki Sugimoto Masahiko Koike Michitaka Fujiwara Yasuhiro Kodera | 2014 | J. Surg. Oncol2014，，2： | 1 |
| 7 | Clinical significance of expression and epigenetic profiling of TUSC1 in gastric cancer显示文摘 | Mitsuro Kanda Dai Shimizu Shuji Nomoto Soki Hibino Hisaharu Oya Hideki Takami Daisuke Kobayashi Suguru Yamada Yoshikuni Inokawa Chie Tanaka Tsutomu Fujii Hiroyuki Sugimoto Masahiko Koike Michitaka Fujiwara Yasuhiro Kodera | 2014 | Oncol2014，，2： | 1 |
| 8 | Pitavastatin Reduces Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Ligands in Hypercholesterolemic Humans显示文摘 | Tetsuya Matsumoto Masatoshi Fujita Tatsuya Sawamura Akemi Kakino Yuko Sato Yoshiko Fujita Haruo Matsuda Mamoru Nakanishi Kagehiro Uchida Izuru Nakae Hiroshi Kanda Akira Yoshida Kunihisa Miwa Hideki Hayashi Kenichi Mitsunami Minoru Horie | 2010 | Lipids2010，，4： | 1 |
| 9 | Energy-ef cient coal dewatering using liquefied dimethyl ether 显示文摘 | Hideki Kanda Hisao Makino | 2010 | Fuel2010，，89： | 1 |
| 10 | Evaluation of MAGE‐D4 expression in hepatocellular carcinoma in Japanese patients显示文摘 | Hideki Takami Mitsuro Kanda Hisaharu Oya Soki Hibino Hiroyuki Sugimoto Masaya Suenaga Suguru Yamada Yoko Nishikawa Mikako Asai Tsutomu Fujii Shuji Nomoto Yasuhiro Kodera | 2013 | J Surg Oncol2013，，8： | 1 |
| 11 | Preparation of highly dispersed core-shell-type titania nanocapsules containing a single Ag nanoparticle显示文摘 | Hideki Sakai Takashi Kanda Hirobumi Shibata | 2006 | The Journal of the American Chemical Society2006，128，15： | 1 |
| 12 | Superior Mesenteric Venous Thrombosis after Laparoscopic Exploration for Small Bowel Obstruction显示文摘 | Hideki Katagiri Shozo Kunizaki Mayu Shimaguchi Yasuo Yoshinaga Yukihiro Kanda Alan T. Lefor Ken Mizokami S. Bhatt M. Güvener S. Landen | 2013 | Case Reports in Surgery2013，，： | 1 |
| 13 | A case-control study of bronchiolitis obliterans syndrome following allogeneic hematopoietic stem cell transplantation显示文摘 | Hideki Nakasone Junya Kanda Shingo Yano | 2013 | Transplant international : official journal of the European Society for Organ Transplantation2013，26，6： | 1 |
| 14 | Preparation of highly dispersed core/shell-type titania nanocapsules containing a single Ag nanoparticle 显示文摘 | Hideki S Kanda T Shibata H | 2006 | J Am chem Soc2006，128，： | 1 |
| 15 | α-FETOPROTEIN PRODUCING URACHAL TUMOR显示文摘 | HIDEAKI KISE HIDEKI KANDA NORIO HAYASHI KIMINOBU ARIMA MAKOTO YANAGAWA JUICHI KAWAMURA | 2000 | The Journal of Urology2000，，2： | 1 |
| 16 | Securitization in Japan显示文摘 | | 1998 | Duke J Comp & Int''l L1998，，： | 1 |
| 17 | Micronization of curcumin with biodegradable polymer by supercritical anti-solvent using micro swirl mixer显示文摘 | Kimthet Chhouk Wahyudiono Hideki Kanda Shin-Ichro Kawasaki Motonobu Goto | 2018 | Frontiers of Chemical Science and Engineering2018，12，1： | 0 |
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