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| 1 | Impact of metastatic lymph node ratio in node-positive colorectal cancer显示文摘Colorectal cancer(CRC) is one of the most common malignant diseases in the world.Presently,the most widely used staging system for CRC is the tumor nodes metastasis classification system,which classifies patients into prognostic groups according to the depth of the primary tumor,presence of regional lymph node(LN) metastases,and evidence of distant metastatic spread.The number of LNs with confirmed metastasis is related to the severity of the disease,but this number depends on the number of LNs retrieved,which varies depending on patient age,tumor grade,surgical extent,and tumor site.Numerous studies and a recent structured review have demonstrated associated improvements in the survival of CRC patients with increasing numbers of LNs retrieved for examination.Hence,the impact of lymph node ratio(LNR),defined as the number of metastatic LNs divided by the number of LNs retrieved,has been investigated in various malignancies,including CRC.In this editorial,we review the literature demonstrating the clinicopathological significance of LNR in CRC pati-ents.Some reports have indicated the advantage of considering the LNR compared to the number of LNs retrieved and/or LN status.When the LNR is taken into consideration for survival analysis,the number of LNs retrieved and/or the LN status is not always found to be a prognostic factor.The cut-off points for LNRs were proposed in numerous studies.However,optimal thresholds for LNRs have not yet received consensus.It is still unclear whether the LNR has more prognostic validity than N stage.For all these reasons,the potential advantages of LNRs in the staging system should be investigated in large prospective data sets. | Shingo Noura Masayuki Ohue Shingo Kano Tatsushi Shingai Terumasa Yamada Isao Miyashiro Hiroaki Ohigashi Masahiko Yano Osamu Ishikawa | 2010 | World Journal of Gastrointestinal Surgery2010，2，3： | 7 |
| 2 | Clinical benefit of surgery for stage IV colorectal cancer with synchronous peritoneal metastasis显示文摘 | Hirotoshi Kobayashi Kenjiro Kotake Kimihiko Funahashi Kazuo Hase Koichi Hirata Tsuneo Iiai Shingo Kameoka Yukihide Kanemitsu Koutarou Maeda Akihiko Murata Masayuki Ohue Kazuo Shirouzu Keiichi Takahashi Toshiaki Watanabe Hideaki Yano Toshimasa Yatsuoka Yoj | 2014 | Journal of Gastroenterology2014，，4： | 2 |
| 3 | Comparison of Autologous Hematopoietic Cell Transplantation and Chemotherapy as Postremission Treatment in Non-M3 Acute Myeloid Leukemia in First Complete Remission显示文摘 | Kensuke Usuki Saiko Kurosawa Naoyuki Uchida Kazuaki Yakushiji Fusako Waki Eijo Matsuishi Kumiko Kagawa Tatsuo Furukawa Yoshinobu Maeda Manabu Shimoyama Hiroatsu Ago Yujiro Yamano Shingo Yano Naohito Fujishima Yasushi Takamatsu Tetsuya Eto Michihiro Hidaka | 2012 | Clinical Lymphoma Myeloma and Leukemia2012，，6： | 1 |
| 4 | Encapsulated vascular endothelial growth factor-secreting cell grafts have neuroprotective and angiogenic effects on focal cerebral ischemia显示文摘 | Yano A Shingo T Takeuchi A | 2005 | J Neurosurg2005，103，1： | 1 |
| 5 | Single-incision laparoscopic cecectomy for low-grade appendiceal mucinous neoplasm after laparoscopic rectectomy显示文摘In this case report,we discuss single-incision laparoscopic cecectomy for low-grade appendiceal neoplasm after laparoscopic anterior resection for rectal cancer.The optimal surgical therapy for low-grade appendiceal neoplasm is controversial;currently,the options include appendectomy,cecectomy,right hemicolectomy,and open or laparoscopic surgery.Due to the risk of pseudomyxoma peritonei,complete resection without rupture is necessary.We have encountered 5 cases of lowgrade appendiceal neoplasm and all 5 patients had no lymph node metastasis.We chose the appendectomy or cecectomy without lymph node dissection if preoperative imaging studies did not suspect malignancy.In the present case,we performed cecectomy without lymph node dissection by single-incision laparoscopic surgery(SILS),which is reported to be a reduced port surgery associated with decreased invasiveness and patient stress compared with conventional laparoscopic surgery.We are confident that SILS is a feasible alternative to traditional surgical procedures for borderline tumors,such as low-grade appendiceal neoplasms. | Shiki Fujino Norikatsu Miyoshi Shingo Noura Tatsushi Shingai Yasuhiko Tomita Masayuki Ohue Masahiko Yano | 2014 | World Journal of Gastrointestinal Surgery2014，6，5： | 1 |
| 6 | CEA-Antigen and SCC-Antigen mRNA Expression in Peripheral Blood Predict Hematogenous Recurrence After Resection in Patients with Esophageal Cancer显示文摘 | Koji Tanaka Masahiko Yano Masaaki Motoori Kentaro Kishi Isao Miyashiro Tatsushi Shingai Kunihito Gotoh Shingo Noura Hidenori Takahashi Masayuki Ohue Terumasa Yamada Hiroaki Ohigashi Takashi Yamamoto Tomoyuki Yamasaki Yuichiro Doki Osamu Ishikawa | 2010 | Annals of Surgical Oncology2010，，： | 1 |
| 7 | Encapsulated vascular endothelial growth factor-secreting cell grafts have neuroprotective and angiogenic effects on focalcerebral ischemia 显示文摘 | Yano A Shingo T Takeuchi A | 2005 | J Neurosurgery2005，103，1： | 1 |
| 8 | Encapsulated vascular endothelial growth factor-secreting cell grafts have neuroprotective and angiogenic effects on focal cerebral ischemia 显示文摘 | Yano A Shingo T Takeuchi A | 2005 | J Neurosurg2005，103，1： | 1 |
| 9 | Chemical modification of glycyrrhetinic acid in relation to the biological activities显示文摘 | Shoji Shibata Kunio Takahashi Shingo Yano | 1987 | Chemical and Pharmaceutical Bulletin1987，35，5： | 1 |
| 10 | Encapsulated vascular endothelial growth factor-secreting cell grafts have neuroprotective and angiogenic effects on focal cerebral ischemia显示文摘 | Yano A Shingo T Takeuchi A | 2005 | J Neurosurg2005，103，1： | 1 |
| 11 | Evaluation of the lateral sentinel node by indocyanine green for rectalcancer based on micrometastasis determined by reverse transcriptase-polymerasechain reaction显示文摘 | Shingo Noura Masayuki Ohue Yosuke Seki Takashi Yamamoto Atsushi Idota Junko Fujii Tomoyuki Yamasaki Hiromu Nakajima Kohei Murata Masao Kameyama Terumasa Yamada Isao Miyashiro Hiroaki Ohigashi Masahiko Yano Osamu Ishikawa Shingi Imaoka | 2008 | Oncology Reports2008，，4： | 1 |
| 12 | Encapsulated vascular endothelial growth factor-secreting cell grafts have neuroprotective and angiogenic effects on focal cerebral ischemia显示文摘 | Yano A Shingo T Takeuchi A | 2005 | J Neurosurg2005，103，1： | 1 |
| 13 | Long-Term Prognostic Value of Conventional Peritoneal Lavage Cytology in Patients Undergoing Curative Colorectal Cancer Resection显示文摘 | Shingo Noura Masayuki Ohue Yosuke Seki Masahiko Yano Osamu Ishikawa Masao Kameyama | 2009 | Diseases of the Colon & Rectum2009，，7： | 1 |
| 14 | Efficacy of subcutaneous penrose drains for surgical site infections in colorectal surgery显示文摘AIM: To investigate whether a subcutaneous penrose drain would decrease the superficial surgical site infection (s-SSI) rate in elective colorectal surgery. METHODS: This is a comparative study of the historical control type. Intervention consisted of the use of penrose drain in elective open colorectal surgical wounds. The outcome was an incidence of s-SSI. The patients were risk stratified according to the depth of subcutaneous tissue.RESULTS: There were 131 patients (40 patients with high s-SSI risk) in the prior period (from July 2008 to June 2009, when no penrose drains were inserted) and 151 patients (75 patients with high s-SSI risk) in the latter period (from June 2010 to November 2011, when penrose drains were inserted). The overall s-SSI rate was 6.1% and 5.3% during the two periods (P = 0.770), and the s-SSI rate in the high s-SSI risk group was 15.0% and 8.0% (P = 0.242).CONCLUSION: Although penrose drain was not observed to significantly reduce s-SSI, there tended to be a reduced risk of s-SSI in the high s-SSI risk group. | Shinya Imada Shingo Noura Masayuki Ohue Tatsushi Shingai Toshinori Sueda Kentaro Kishi Terumasa Yamada Hiroaki Ohigashi Masahiko Yano Osamu Ishikawa | 2013 | World Journal of Gastrointestinal Surgery2013，5，4： | 1 |
| 15 | Chemical modification of glycyrrhetinic acid in relation to the biologicai activities 显示文摘 | Soji Shibata Kunio Takahashi Shingo Yano | 1987 | Chemical and Pharmaceutical Bulletin1987，35，5： | 1 |
| 16 | Accumulation of Excess Visceral Fat Is a Risk Factor for Pancreatic Fistula Formation After Total Gastrectomy显示文摘 | Koji Tanaka MD Isao Miyashiro MD Masahiko Yano MD Kentaro Kishi MD Masaaki Motoori MD Yousuke Seki MD Shingo Noura MD Masayuki Ohue MD Terumasa Yamada MD Hiroaki Ohigashi MD Osamu Ishikawa MD | 2009 | Annals of Surgical Oncology2009，，6： | 1 |
| 17 | Cell therapy for cerebra ischemia using vascular endothelial growth factor-secreting cells 显示文摘 | Shingo T Date I Yano A | 2003 | Int Congr Ser2003，125，4： | 1 |
| 18 | Accumulation of Excess Visceral Fat Is a Risk Factor for Pancreatic Fistula Formation After Total Gastrectomy显示文摘 | Koji Tanaka MD Isao Miyashiro MD Masahiko Yano MD Kentaro Kishi MD Masaaki Motoori MD Yousuke Seki MD Shingo Noura MD Masayuki Ohue MD Terumasa Yamada MD Hiroaki Ohigashi MD Osamu Ishikawa MD | 2009 | Annals of Surgical Oncology2009，，6： | 1 |
| 19 | Encapsulated vascular endothelial growth factor-secreting cell grafts have neuroprotecfive and angiogenic effects on focal cerebral ischemia 显示文摘 | Yano A Shingo T Takeuchi A | 2005 | J Neurosurg2005，103，1： | 1 |
| 20 | Cell therapy for cerebral ischemia using vascular endothelial growth factor2secreting cells显示文摘 | Date I Yano A | 2003 | International Congress Series2003，125，： | 1 |
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