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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | The International Position on Laparoscopic Liver Surgery: The Louisville Statement, 2008显示文摘 | Joseph F. Buell Daniel Cherqui David A. Geller Nicholas O’Rourke David Iannitti Ibrahim Dagher Alan J. Koffron Mark Thomas Brice Gayet Ho Seong Han Go Wakabayashi Giulio Belli Hironori Kaneko Chen-Guo Ker Olivier Scatton Alexis Laurent Eddie K. Abdalla Pr | 2009 | Annals of Surgery2009，，3： | 2 |
| 3 | The International Position on Laparoscopic Liver Surgery: The Louisville Statement, 2008显示文摘 | Joseph F. Buell Daniel Cherqui David A. Geller Nicholas O'Rourke David Iannitti Ibrahim Dagher Alan J. Koffron Mark Thomas Brice Gayet Ho Seong Han Go Wakabayashi Giulio Belli Hironori Kaneko Chen-Guo Ker Olivier Scatton Alexis Laurent Eddie K. Abdalla Pr | 2009 | Annals of Surgery2009，，3： | 2 |
| 4 | Risk stratification in symptomatic intracranial atherosclerotic disease with conventional vascular risk factors and cerebral haemodynamics显示文摘Background and purpose Symptomatic intracranial atherosclerotic stenosis(sICAS)is associated with a considerable risk of recurrent stroke despite contemporarily optimal medical treatment.Severity of luminal stenosis in sICAS and its haemodynamic significance quantified with computational fluid dynamics(CFD)models were associated with the risk of stroke recurrence.We aimed to develop and compare stroke risk prediction nomograms in sICAS,based on vascular risk factors and these metrics.Methods Patients with 50%-99%sICAS confirmed in CT angiography(CTA)were enrolled.Conventional vascular risk factors were collected.Severity of luminal stenosis in sICAS was dichotomised as moderate(50%-69%)and severe(70%-99%).Translesional pressure ratio(PR)and wall shear stress ratio(WSSR)were quantified via CTA-based CFD modelling;the haemodynamic status of sICAS was classified as normal(normal PR&WSSR),intermediate(otherwise)and abnormal(abnormal PR&WSSR).All patients received guideline-recommended medical treatment.We developed and compared performance of nomograms composed of these variables and independent predictors identified in multivariate logistic regression,in predicting the primary outcome,recurrent ischaemic stroke in the same territory(SIT)within 1 year.Results Among 245 sICAS patients,20(8.2%)had SIT.The D2H2A nomogram,incorporating diabetes,dyslipidaemia,haemodynamic status of sICAS,hypertension and age≥50 years,showed good calibration(P for Hosmer-Lemeshow test=0.560)and discrimination(C-statistic 0.73,95%CI 0.60 to 0.85).It also had better performance in risk reclassification and provided larger net benefits in decision curve analysis,compared with nomograms composed of conventional vascular risk factors only,and plus the severity of luminal stenosis in sICAS.Sensitivity analysis in patients with anterior-circulation sICAS showed similar results.Conclusions The D2H2A nomogram,incorporating conventional vascular risk factors and the haemodynamic significance of sICAS as assessed in CFD models,could be a useful tool to stratify sICAS patients for the risk of recurrent stroke under contemporarily optimal medical treatment. | Xuan Tian Hui Fang Linfang Lan Hing Lung Ip Jill Abrigo Haipeng Liu Lina Zheng Florence S Y Fan Sze Ho Ma Bonaventure Ip Bo Song Yuming Xu Jingwei Li Bing Zhang Yun Xu Yannie O Y Soo Vincent Mok Ka Sing Wong Thomas W Leung Xinyi Leng | 2023 | Stroke & Vascular Neurology2023，8，1： | 2 |
| 5 | p38gamma MAPK regulation of glucose transporter expression and glucose uptake in L6 myotubes and mouse skeletal muscle显示文摘 | Ho R C Alcazar O Fujii N | 2004 | Am J Physiol Regul Integr Comp Physiol2004，286，2： | 1 |
| 6 | Heart Disease and Stroke Statistics—2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee显示文摘 | Wayne Rosamond Katherine Flegal Karen Furie Alan Go Kurt Greenlund Nancy Haase Susan M. Hailpern Michael Ho Virginia Howard Brett Kissela Steven Kittner Donald Lloyd-Jones Mary McDermott James Meigs Claudia Moy Graham Nichol Christopher O’Donnell Veroniqu | 2008 | Circulation2008，，4： | 1 |
| 7 | Social and economic effects of non-ulcer dyspepsia 显示文摘 | Nyr6n O Adami HO Gustavsson S et aI | 1985 | Scand J Gastroenterol Suppl1985，109，： | 1 |
| 8 | Extension of human cell lifespan by nicotinamide phosphoribosyltransferase显示文摘 | van der Veer E Ho C O'Neil C | 2007 | J Biol Chem2007，282，10： | 1 |
| 9 | The pharmacokinetics and different yegimens of misoprostol in early first-trmester medical abortion显示文摘 | Tang O S Ho P C | 2006 | Contraception2006，74，1： | 1 |
| 10 | Mass spectrometry-based proteomic analysis of urine in acute kidney injury following cardiopulmonary bypass:a nested case-control study显示文摘 | Ho J Lucy M Krokhin O | 2009 | Am J Kidney Dis2009，53，4： | 1 |
| 11 | Ideopolitical shifts and changes in moral education policy in China 显示文摘 | LEE W O HO C H | 2005 | Journal of Moral Education2005，43，4： | 1 |
| 12 | cDNA cloning and functional char- acterization of a novel splice variant of c-Cbl-associated protein from mouse skeletal muscle显示文摘 | Alcazar O Ho RC Fujii N | 2004 | Biochem Biophys Res Commun2004，317，1： | 1 |
| 13 | H5-type influenza virus hemagglutinin is functionally recognized by the natural killer-activating receptor NKp44显示文摘 | Ho JW Hershkovitz O Peiris M | 2008 | J Virol2008，82，4： | 1 |
| 14 | Dexmedetomidine directly increases tau phosphorylation显示文摘 | Huang C Ho Y S Ng O T | 2015 | J Alzheimers Dis2015，44，3： | 1 |
| 15 | Crash and Occupant Predictors of Pulmonary Contusion显示文摘 | James V. O’Connor Joseph A. Kufera Timothy J. Kerns Deborah M. Stein Shiu Ho Patricia C. Dischinger Thomas M. Scalea | 2009 | The Journal of Trauma: Injury, Infection, and Critical Care2009，，4： | 1 |
| 16 | Preparation of microemulsions using polyglycerol fatty acid esters as surfactant for the delivery of protein drugs 显示文摘 | Ho H O HsiaoC C Sheu M T | 1996 | J Pharm Sci1996，85，2： | 1 |
| 17 | Effectiveness of Intratympanic Dexametha sone Injection in Sudden-deafness Patients as Salvage Treatment显示文摘 | Ho H O Lin H C | 2004 | Laryngoscope2004，114，7： | 1 |
| 18 | Elevated galec- tin-3 precedes the development of CKD显示文摘 | O'Seaghdha CM Hwang SJ Ho JE | 2013 | J Am Soc Nephrol2013，24，9： | 1 |
| 19 | Process development of an acellular dermal matrix (ADM) for biomedical applications 显示文摘 | Chen R N Ho H O Tsai Y T | 2004 | Biomaterials2004，25，： | 1 |
| 20 | Atrial but not ventricular fibrosis in mice expressing a mutant transforming growth factor-beta ( 1 ) transgene in the heart显示文摘 | Nakajima H Nakajima HO Salcher O | 2000 | Circ Res2000，86，5： | 1 |
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