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| 1 | 建筑中人行为模拟研究现状和展望显示文摘人行为是影响建筑能耗的重要因素,近几年成为建筑能耗模拟领域的研究热点。在过去的几十年中已有大量的相关研究,致力于通过实测建立事件或环境相关的人行为模型,但是,目前的人行为研究中还需要进一步发展,以满足工程实际的需要。本文回顾了人行为研究的研究现状,总结了在研究方法上现存的问题,从数据采集、模型建立、模型验证和软件开发4个从建模到应用的阶段,提出了人行为研究的未来展望。并讨论了人行为研究中尚存在的一些共性问题,例如:在实测中应进一步探讨采样的规模和实验室研究的可行性,建立人行为模型时应明确模型面向的应用层次,合理的数学形式、参数选择的方法、多因素多行为多人的模拟等尚待研究,针对模型的验证应以实际应用为指向确定验证的指标,采取科学有效的验证方法,以及在人行为相关软件的开发中,应定义良好的软件结构和接口,建立统一的描述框架,以相对独立的模块形式实现和模拟软件的交互。希望这些探讨能为将来的人行为研究提供新的思路,以推动人行为和建筑能耗模拟事业的发展。 | 燕达 丰晓航 王闯 Hong Tianzhen William O’Brien H.Burak Gunay Farhang Tahmasebi Ardeshir Mahdavi | 2015 | 建筑科学2015，31，10： | 23 |
| 2 | Association of Dietary Pattern during Pregnancy and Gestational Diabetes Mellitus: A Prospective Cohort Study in Northern China显示文摘Objective To examine the association of maternal dietary patterns during pregnancy with gestational diabetes mellitus(GDM) in northern China.Methods The dietary intakes of pregnant women were recorded twice by 24‐hour dietary recalls for three days prior to having been diagnosed with GDM, at 5‐15 and 24‐28 gestational weeks, respectively.GDM was diagnosed, and serum glycosylated hemoglobin(HbA1c) was measured at 24‐28 weeks.Dietary patterns were assessed by factor analysis. The association of the dietary pattern with GDM and HbA1c was examined by multiple logistic models.Results Of 753 participants, 64(8.5%) were diagnosed with GDM. Four dietary patterns were identified: Western pattern(dairy, baked/fried food and white meat), traditional pattern(light‐colored vegetables, fine grain, red meat and tubers), mixed pattern(edible fungi, shrimp/shellfish and red meat)and prudent pattern(dark‐colored vegetables and deep‐sea fish). Compared with the prudent pattern,both the Western pattern and the traditional pattern were associated with an increased risk of GDM(a OR = 4.40, 95% CI: 1.58‐12.22; a OR = 4.88, 95% CI: 1.79‐13.32) and a high level of HbA1c(a OR = 12.37,95% CI: 1.47‐103.91; a OR = 26.23, 95% CI: 2.54‐270.74). Compared to the lowest quartile(Q), Q3 of the Western pattern scores and Q3‐Q4 of the traditional pattern scores were associated with a higher risk of GDM.Conclusion The consumption of the Western pattern or the traditional pattern during pregnancy may increase the risk of GDM. | DU Hong Yi JIANG Hong O Karmin CHEN Bo XU Lin Ji LIU Shu Ping YI Jian Ping HE Geng Sheng QIAN Xu | 2017 | Biomedical and Environmental Sciences2017，30，12： | 16 |
| 3 | Roles of P-glycoprotein and multidrug resistance protein in transporting para-aminosalicylic acid and its N-acetylated metabolite in mice brain显示文摘目的: Para-aminosalicylic 酸(舞步) 在导致 manganism 的 neurotoxicity (manganism ) 的处理是有效的。在这研究,我们在通过血大脑障碍搬运舞步和它的 N-acetylated 代谢物 AcPAS 调查了 P-glycoprotein (MDR1a ) 和 multidrug 抵抗蛋白质(MRP ) 的角色。 | Lan HONG Cong XU Stefanie O'NEAL Hui-chang BI Min HUANG Wei ZHENG Su ZENG | 2014 | Acta Pharmacologica Sinica2014，35，12： | 4 |
| 4 | Heart Disease and Stroke Statistics—2006 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee显示文摘 | Thomas Thom Nancy Haase Wayne Rosamond Virginia J. Howard John Rumsfeld Teri Manolio Zhi-Jie Zheng Katherine Flegal Christopher O’Donnell Steven Kittner Donald Lloyd-Jones David C. Goff Yuling Hong Robert Adams Gary Friday Karen Furie Philip Gorelick Bret | 2006 | Circulation2006，，6： | 3 |
| 5 | Prohibitin(PHB)interacts with AKT in mitochondria to coordinately modulate sperm motility显示文摘Prohibitin(PHB),an evoluti on arily con served mitochondrial inner membra ne protein,is highly expressed in cells that require strong mitoch on drial function.Recently,we dem on strated that the deleti on of Phb in spermatocytes results in impaired mitochondrial function.In addition,PHB expression in the mitochondrial sheath of human sperm has a significantly negative correlation with mitochondrial reactive oxygen species levels,but a positive one with mitochondrial membrane potential and sperm motility.These results suggest that mitochondrial PHB expression plays a role in sperm motility.However,the mechanism of PHB-mediated regulation of sperm motility remai ns unk nown.Here,we dem on strate for the first time that PHB interacts with protei n kinase B(AKT)and exists in a complex with phospho-PHB(pT258)and phospho-AKT in the mitochondrial sheath of murine sperm,as determined using colocalization and coimmunoprecipitation assays.After blocking AKT activity using wortmannin(a phosphatidylinositol 3-kinase[PI3K]inhibitor),murine sperm have significantly(P<0.05)decreased levels of phospho-PHB(pT258)and the total and progressive motility.Furthermore,significantly(P<0.05)lower levels of phospho-PI3K P85 subunit a+γ(pY199 and pY46)and phospho-AKT(pS473;pT308)are found in sperm from infertile asthenospermic and oligoasthenospermic men compared with no rmospermic subjects,which suggest a reduced activity of the PI3K/AKT pathway in these in fertile subjects.Importantly,these sperm from infertile subjects also have a significantly(P<0.05)lower level of phospho-PHB(pT258).Collectively,our findings suggest that the interaction of PHB with AKT in the mitochondrial sheath is critical for sperm motility,where PHB phosphorylation(pT258)level and PI3K/AKT activity are key regulatory factors. | Xiao-Hui Li Ran-Ran Chai Guo-Wu Chen Ling-Fei Zhang Wen-Jing Tan-Tai Hui-Juan Shi Patricia A Martin-DeLeon Wai-Sum O Hong Chen | 2020 | Asian Journal of Andrology2020，22，6： | 3 |
| 6 | Safety of endovascular therapy for symptomatic intracranial artery stenosis:a national prospective registry显示文摘Introduction The safety outcomes of endovascular therapy for intracranial artery stenosis in a real-world stetting are largely unknown.The Clinical Registration Trial of Intracranial Stenting for Patients with Symptomatic Intracranial Artery Stenosis(CRTICAS)was a prospective,multicentre,real-world registry designed to assess these outcomes and the impact of centre experience.Methods 1140 severe,symptomatic intracranial arterial stenosis(ICAS)patients treated with endovascular therapy were included from 26 centres,further divided into three groups according to the annual centre volume of intracranial angioplasty and stent placement procedures over 2 years:(1)high volume for≥25 cases/year;(2)moderate volume for 10–25 cases/year and(3)low volume for<10 cases/year.Results The rate of 30-day stroke,transient ischaemic attack or death was 9.7%(111),with 5.4%,21.1%and 9.7%in high-volume,moderate-volume and low-volume centres,respectively(p<0.05).Multivariable logistic regression confirmed high-volume centres had a significantly lower primary endpoint compared with moderate-volume centres(OR=0.187,95%CI:0.056 to 0.627;p≤0.0001),while moderate-volume and low-volume centres showed no significant difference(p=0.8456).Conclusion Compared with the preceding randomised controlled trials,this real-world,prospective,multicentre registry shows a lower complication rate of endovascular treatment for symptomatic ICAS.Non-uniform utilisation in endovascular technology,institutional experience and patient selection in different volumes of centres may have an impact on overall safety of this treatment. | Yabing Wang Tao Wang Adam Andrew Dmytriw Kun Yang Liqun Jiao Huaizhang Shi Jie Lu Tianxiao Li Yujie Huang Zhenwei Zhao Wei Wu Jieqing Wan Qinjian Sun Bo Hong Yongli Li Liyong Zhang Jianfeng Chu Qiong Cheng Yiling Cai Pengfei Wang Qi Luo Hua Yang Baijing Dong Yang Zhang Jun Zhao Zuoquan Chen Wei Li Xiaoxin Bai Weiwen He Xueli Cai Maimai Ti Osama O Zaidat | 2022 | Stroke & Vascular Neurology2022，7，2： | 3 |
| 7 | 2004年加拿大预防血透病人医院血流感染的成本-效益分析显示文摘目的:血液透析相关的血流感染是一个严重的公共健康问题,因为加拿大的血液透析病人从1996年到2005翻了一番。本研究目的在于确定加拿大医院血流感染的成本,估算在综合性医院中建立感染控制项目的成本,并进行成本-效益分析。材料与方法:用加拿大医院感染监测项目的数据来估算医院血流感染的发生率。用加拿大健康信息所数据来估算2004年加拿大平均一次血流感染住院的额外成本。建立和维护一个感染控制项目的成本用美国疾病预防与控制中心1985年的成本换算为2004年的加拿大成本来估算。假设感染控制项目能降低医院血流感染病例的20%~30%。结果:2004年的加拿大15278名血液透析病人中估计共有2524人发生血流感染。全年用于治疗血流感染的成本估计为4901万加元。医院血流感染预防和人力资源的总投资成本为815万加元。建立医院感染控制项目后能带来1452万加元的医疗成本节约。效益成本比在1.0:1到1.8:1之间。结论:本研究提供的证据表明,如果医院感染控制项目能降低20%~30%的感染,该项目的经济效益将远超过增加的成本。医院感染控制项目将带来双重效益:节约货币成本的同时改善医疗质量。 | Zhiyong Hong MD DrPH Jun Wu PhD Crystal O'Leary BHSc Clem Tisdell James Gomes Shi-Wu Wen Howard Njoo 李洪超 | 2010 | 中国药物经济学2010，，1： | 2 |
| 8 | 生物炭在柑橘皮厌氧发酵中作用机理研究显示文摘该研究主要调查柑橘皮废料厌氧消化能力在不同类型的生物炭和不同比率下的影响。柑橘皮对厌氧消化有抑制作用。生物炭的存在有两种影响:相对于只有柑橘皮废料的培养来说,它减少了迟滞期的长度,并且使甲烷的产量更高。微生物迟滞期随着柑橘皮与生物炭比例的增加而降低,在比例为2∶1时停滞期最长,为9.4 d,在比例为1∶3时迟滞期最短,为7.5 d。生物炭和柑橘皮培养中累积的甲烷产量在163.9到186.8 mLCH4 ·g^-1VS之间变动,而只有柑橘皮培养中的甲烷产量只有165.9 mLCH4 ·g^-1VS。在检测生物炭材料时发现了推测的产甲烷菌群。D-柠檬烯吸附和微生物固定化的协同作用在生物炭的影响下会提高厌氧消化的性能。 | Michael O Fagbohungbe Ben M J Herbert Lois Hurst Hong Li Shams Q Usmani Kirk T Semple 张冀川(译) | 2019 | 中国沼气2019，37，5： | 2 |
| 9 | 冠状动脉钙化用于指导个性化阿司匹林治疗以预防心血管病:基于多民族动脉粥样硬化研究显示文摘最近美国心脏病学会/美国心脏协会(American College of Cardiology/American Heart Association,ACC/AHA)的一级预防指南建议,低剂量阿司匹林治疗仅适用于年龄40~70岁、患动脉粥样硬化性心血管病(atherosclerotic cardiovascular disease,ASCVD)风险较高,但出血风险不高的成年人。然而,尚不清楚如何更准确地识别出这些患者。根据2019年降低心血管病相对危险度和出血风险的阿司匹林荟萃分析研究数据,本研究旨在评估冠状动脉钙化(coronary artery calcium,CAC)在指导阿司匹林在一级预防中如何使用的价值。 | 周卫(译) 叶鹏(摘/审校) Achirica MC Miedema MD McEvoy JW Rifai MA Greenland P Dardari Z Budoff M Blumenthal RS Yeboah J Duprez DA Mortensen MB Dzaye O Hong J Nasir K Blaha MJ | 2020 | 中华高血压杂志2020，28，4： | 2 |
| 10 | Additivity and associative effects of metabolizable energy and amino acid digestibility of com,soybean meal,and wheat red dog for white pekin ducks显示文摘 | Hong D R agland D Adeola O | 2002 | Poultry science2002，80，： | 1 |
| 11 | Physical properties of gelidium corneum-gelatin blend films containing grapefruit seed extract or green tea extract and its application in the packaging of pork loins显示文摘 | HONG Y H LIM G O SONG K B | 2009 | Food Science2009，74，1： | 1 |
| 12 | Surface analysis of clinically failed dental implant fixture显示文摘 | CHOE H C HONG K S KO Y M KIM B O | 2006 | J Kor Inst Met & Mater2006，44，： | 1 |
| 13 | Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy显示文摘 | Hong J Y Han S W Kim W O | 2010 | Br J Anaesth2010，105，4： | 1 |
| 14 | Soil pH effect on phosphate induced cadmium precipitation in arable soil显示文摘 | Hong C O Owens V N Kim Y G | 2014 | Bulletin of Environmental Contamination and Toxicology2014，93，1： | 1 |
| 15 | Tan Aptamer-assisted cell targeting and its application in cell-based immunotherapy of cancer 显示文摘 | Xiang ling Xiong Meghan O'Donoghue Wei hong | 2012 | FASEBJ2012，26，： | 1 |
| 16 | Control of Molecular Weight Distribution in Propylene Polymerization with ZieglerNatta/Metallocene Catalyst Mixtures显示文摘 | Ahn T O Hong S C Kim J H | 1998 | J Appl Polym Sci1998，67，13： | 1 |
| 17 | Nicotinic acetylcholine receptor α 7 subunit is an essential regulator of inflammation 显示文摘 | Hong W Man Y Mahendar O | 2003 | Nature2003，421，： | 1 |
| 18 | Pathways for the Hydrolysis of Phor-ate:Product Studies by 31P NMR and GC-MS显示文摘 | Hong F Pehkonen S O Brooks E | 2000 | J Agric Food Chem2000，48，： | 1 |
| 19 | Atmospheric mercury deposition on Fanjing Mountain Nature Reserve, Guizhou, China显示文摘 | Xiao Z F Sommar J Lindqvist O Hong T He J L | 1998 | Chemosphere1998，36，10： | 1 |
| 20 | Intergrated sensors based Mg- doped SrTiO3 fabricated by screen- printing 显示文摘 | Zheng Hong Sorensen O T | 2000 | Sensors and Actuators B2000，68，： | 1 |
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