|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | New chronological evidence for Yanshanian diagenetic mineralization in China's Altay orogenic belt显示文摘Granitoids and related pegmatitic rare-metal deposits are widespread in China’s Altay region,they used to be considered as Hercynian rocks and mineral deposits.Reported here are the^40Ar^39Ar ages of potassium-rich minerals (muscovite and microcline)in the Koktokay pegmatitic rare-metal orefield and whole-rock as well as quartz fluid-inclusion Rb-Sr isochron ages of granite and ores in the Shangkelan pegmatite rare-metal orefield. The ages indicate that there are Yanshanian Diagenetic Mineralization events happening in China’s Altay orogenic belt and that formation of the famous Koktokay No.3 pegmatitic rare-metal deposit endured about 30 Ma of magmatic crystallization differentiation. | Fuwen Chen Huaqin Li Denghong Wang Hong Cai Wen Chen | 2000 | Chinese Science Bulletin2000，45，2： | 12 |
| 2 | Generation of seed lipoxygenase-free soybean using CRISPR-Cas9显示文摘Beany flavor induced by three lipoxygenases(LOXs, including LOX1, LOX2, and LOX3)restricts human consumption of soybean. It is desirable to generate lipoxygenase-free new mutant lines to improve the eating quality of soybean oil and protein products. In this study, a pooled clustered regularly interspaced short palindromic repeats(CRISPR)-CRISPRassociated protein 9(Cas9) strategy targeting three GmLox genes(GmLox1, GmLox2, and GmLox3) was applied and 60 T_0 positive transgenic plants were generated, carrying combinations of sg RNAs and mutations. Among them, GmLox-28 and GmLox-60 were gmlox1 gmlox2 gmlox3 triple mutants and GmLox-40 was a gmlox1 gmlox2 double mutant.Sequencing of T_1 mutant plants derived from GmLox-28, GmLox-60, and GmLox-40 showed that mutation in the GmLox gene was inherited by the next generation. Colorimetric assay revealed that plants carrying different combinations of mutations lost the corresponding lipoxygenase activities. Transgene-free mutants were obtained by screening the T_2 generation of lipoxygenase-free mutant lines(GmLox-28 and GmLox-60). These transgeneand lipoxygenase-free mutants could be used for soybean beany flavor reduction without restriction by regulatory frameworks governing transgenic organisms. | Jie Wang Huaqin Kuang Zhihui Zhang Yongqing Yang Long Yan Mengchen Zhang Shikui Song Yuefeng Guan | 2020 | The Crop Journal2020，8，3： | 9 |
| 3 | EMBRYONIC FACTOR 19 Encodes a Pentatricopeptide Repeat Protein that is Essential for the Initiation of Zygotic Embryogenesis in Arabidopsis显示文摘Early embryogenesis is the most fundamental developmental process in biology.Screening of ethyl methanesulfonate(EMS)-mutagenized populations of Arabidopsis thaliana led to the identification of a zygote-lethal mutant embryonic factor 19(fac19)in which embryo development was arrested at the elongated zygote to octant stage.The number of endosperm nuclei decreased significantly in fac19 embryos.Genetic analysis showed fac19 was caused by a single recessive mutation with typical mendelian segregation,suggesting equal maternal and paternal contributions of FAC19 towards zygotic embryogenesis.Positional cloning showed that FAC19 encodes a putative mitochondrial protein with 16 conserved pentatricopeptide repeat(PPR)motifs.The fac19 mutation caused a conversion from hydrophilic serine located in a previously unknown domain to hydrophobic leucine.Crosses between FAC19/fac19 and the T-DNA insertion mutants in the same gene failed to complement the fac19 defects,confirming the identity of the gene.This study revealed the critical importance of a PPR protein-mediated mitochondrial function in early embryogenesis. | Dali Yu Li Jiang Huaqin Gong Chun-Ming Liu | 2012 | Journal of Integrative Plant Biology2012，54，1： | 8 |
| 4 | Effect of Ti substitution on hydrogen storage properties of Zr_(1-x)Ti_xCo (x = 0, 0.1, 0.2, 0.3) alloys显示文摘Zr1-xTixCo(x = 0, 0.1, 0.2, 0.3) alloys were prepared by arc-melting method and the effect of Ti substitution on hydrogen storage properties was studied systematically. Hydrogen desorption pressure-composition-temperature(PCT) measurements were carried out using Sievert's type volumetric apparatus for ZrCo(at 473 K, 573 K and 673 K) and Zr1-xTixCo alloys(at 673 K), respectively. Products after dehydrogenation were characterized by X-ray diffraction(XRD). In addition, the kinetics of Zr1-xTixCo hydride was investigated at 473 K and 673 K,respectively, under hydrogen pressure of 5 MPa. Results showed that Ti substitution for Zr did not change the crystal structure of ZrCo phase.With the increase of temperature from 473 K to 673 K, the extent of disproportionation for ZrCo alloy increased. With Ti content increasing at 673 K, the desorption equilibrium pressure of Zr1-xTixCo-H2 systems elevated and the disproportionation reaction of Zr1-xTixCo alloys was inhibited effectively. Ti substitution decreased the kinetics rate and the effective hydrogen storage capacity of Zr1-xTixCo alloys slightly.Generally speaking, it was found that Zr0.8Ti0.2Co alloy had better anti-disproportionation property with less decrease of effective hydrogen storage capacity which was beneficial to tritium application in the International Thermonuclear Experimental Reactor(ITER). | Yamin Zhao Rongfeng Li Ruihe Tang Boyan Li Ronghai Yu Wei Liu Huaqin Kou Jianbo Meng | 2014 | Journal of Energy Chemistry2014，23，1： | 6 |
| 5 | Sm-Nd and Rb-Sr isotopical ages of magnetite-chlorite formation gold deposit in the volcanic rock area of Late Paleozoic Era,East Tianshan显示文摘Through studying geo-geochemical characteristics and determining Sm-Nd and Rb-Sr isotopical ages in the Kanggur magnetite-chlorite formation gold deposit, some conclusions can be achieved: Sm-Nd isochron age is (290.4 ±7)Ma, Rb-Sr isochron age is (282.3 ±5)Ma, mineralization is Late Hercynian and the formation of this gold deposit is related to the macro- | Jinsheng Ji Huaqin Li Lianchang Zhang Xingke Yang Chengyou Feng | 1999 | Chinese Science Bulletin1999，44，19： | 5 |
| 6 | Nutritional Quality of Mixed Silage of Lablab purpureus and Sweet Sorghum显示文摘[Objective] The paper was to evaluate the fermentation quality of mixed silage of Lablab purpureus and sweet sorghum,and to find out the appropriate mixing ratio.[Method]L.purpureus were mixed with sweet sorghum at different proportions,to identify the sensory character and quality of silage.[Result]The nutrient content of mixed silage of L.purpureus and sweet sorghum at different proportions decreased significantly at 30-60 d,while no significant changes were observed after 60 d.Mixed silage of L.purpureus and sweet sorghum had the best effort at the proportion of 3∶7; followed by the proportion of 5∶5.These two proportions significantly improved dry matter( DM) content and effectively alleviated the crude protein( CP) loss of raw materials; significantly improved the contents of crude fiber and crude ash; and significantly reduce ammonia nitrogen/total nitrogen( AT/TN).[Conclusion]From the perspective of silage quality,the appropriate mixing ratio of L.purpureus and sweet sorghum is 3∶7 or 5∶5. | Liu Hailin Deng Huifen Xu Huaqin Sun Ao | 2017 | Animal Husbandry and Feed Science2017，9，6： | 4 |
| 7 | Significance of VEGF and NF-κB Expression in Thyroid Carcinoma显示文摘OBJECTIVE To investigate the significance of vascular endothelial growth factor (VEGF) and nuclear factor-kappaB (NF-κB) expression in thyroid carcinoma. METHODS The expression of NF-κB and VEGF was determined by im- munohistochemistry in formalin-fixed and paraffin-embedded specimens obtained from 10 normal thyroid tissues (NT), 12 cases of thyroid adeno- ma (TA) and 68 cases of thyroid carcinoma (TC).Differences in expres- sion between NT, TA and TC were statistically analyzed. In addition, in cases of TC, the relationship of NF-κB and VEGF expression with various clinicopathological factors, including histological typing, clinical staging and lymph node metastasis, as well as the correlation between N F - κ B and VEGF expression was examined. RESULTS In contrast to the negative immunoreactivity for VEGF in NT, there was a significantly higher positive incidence (PI) in TA (41.7%, P= 0.040) and TC (75.0%, P<0.001), and a significant difference between TA and TC (P=0.036). Immunoreactivity for NF-κB in NT was negative and significantly higher in TC (63.2%, P<0.001),but not in TA (16.7%, P= 0.481). However the PI difference between TA and TC (P=0.003) was significant. Between the histological types of TC, a significantly higher PI was found in undifferentiated thyroid carcinoma (UTC),namely,100% for VEGF and 90.0% for NF-κB. We also found significant positive relation- ships of VEGF and N F - κ B expression with the clinical stage and lymph node metastasis. Furthermore, a significant positive correlation between VEGF and NF-κB expression in TC was observed. CONCLUSION Our data showed that the expression of VEGF and NF- ΚB/P65 was greater in TC and UTC, and documented their significant positive correlations with the clinical stage and lymph node metastasis in TC. In addition there was a significant positive relationship between their expression, suggesting that they have important roles in TC and that they may be potential targets for gene therapy in TC patients. | Zhenxian Du Haiyan Zhang Daxin Gao Huaqin Wang Yongjun Li Guoliang Liu | 2006 | Chinese Journal of Clinical Oncology2006，3，3： | 3 |
| 8 | Numerical Modeling of Floating Oil Boom Motions in Wave-Current Coupling Conditions显示文摘Containment booms are commonly used in collecting and containing spilled oil on the sea surface and in protecting specific sea areas against oil slick spreading.In the present study,a numerical model is proposed based on the N-S equations in a mesh frame.The proposed model tracks the outline of the floating boom in motion by using the fractional area/volume obstacle representation technique.The boom motion is then simulated by the technique of general moving object.The simulated results of the rigid oil boom motions are validated against the experimental results.Then,the failure mechanism of the boom is investigated through numerical experiments.Based on the numerical results,the effects of boom parameters and dynamic factors on the oil containment performance are also assessed. | SHI Yang LI Shaowu ZHANG Huaqin PENG Shitao CHEN Hanbao ZHOU Ran MAO Tianyu | 2017 | Journal of Ocean University of China2017，16，4： | 2 |
| 9 | A single-stand helical coordination polymer:catena-poly-μ-2,2'-bipyridine-3,3'-dicarboxylato-k3 N,N':O]monohydrate]显示文摘 | Zhang Hongtao Shao Ting Wang Huaqin | 2003 | Acta Crystailogr Sect C2003，59，： | 1 |
| 10 | Combination of two multiplex genome-edited soybean varieties enables customization of protein functional properties显示文摘Dear Editor,Soybean(Glycine max)is a major source of plant-based protein for people worldwide,providing a healthy,affordable,and environmentally friendly alternative to animal-based protein(Montgomery,2003).It has been estimated that there are currently over 12000 food products that contain soy protein(Montgomery,2003).Different food applications of soy protein require distinct properties that affect its function and sensory features.For instance,the sensory quality of soymilk is significantly affected by protein emulsibility,whereas tofu quality is determined by protein-gelling ability(Kinsella,1979). | Mengyan Bai Cuicui Yuan Huaqin Kuang Qian Sun Xinchen Hu Luning Cui Wenxin Lin Chunyan Peng Peng Yue Shikui Song Zebin Guo Yuefeng Guan | 2022 | Molecular Plant2022，15，7： | 1 |
| 11 | Expression and clinical significance of tyrosine phosphatase SHP-2 in colon cancer显示文摘 | Peifen Cai Wenjie Guo HuaQin Yuan Qian Li Weicheng Wang Yang Sun Xiaomin Li Yanhong Gu | 2013 | Biomedicine & Pharmacotherapy2013，，： | 1 |
| 12 | Mineralization and fluid inclusion study of the Shizhuyuan W-Sn-Bi-Mo-F skarn deposit, Hunan Province, China 显示文摘 | Lu Huan-zhang Liu Yimiao Wang Changlie Xu Youzhi Li Huaqin | 2003 | Econ Geol2003，98，5： | 1 |
| 13 | Whole exome sequencing revealed a heterozygous elongation factor Tu GTP-binding domain containing 2(EFTUD2)mutation in a couple experiencing recurrent pregnancy loss显示文摘To the Editor:Recurrent pregnancy loss(RPL)is defined as the failure of two or more clinically recognized pregnancies.[1]Both parental and embryonic/fetal factors are associated with RPL.Parental factors include balanced chromosome rearrangements,maternal antiphospholipid syndrome,uterine anomalies,and hormonal or metabolic disorders.[2]Of the examined products of conception(POC),approximately 60%of early pregnancy losses result from sporadic chromosomal abnormalities in embryos,specifically numeric chromosome errors.However,up to 50%of RPL cases remain unexplainable by known causes.Here,we report a couple who have experienced four consecutive clinical pregnancy losses within 10 weeks of gestation,and describe a novel(elongation factor Tu GTP-binding domain containing 2[EFTUD2],Online Mendelian Inheritance in Man[MIM]#603892)nonsense mutation(c.1012G>T,p.E338∗)found in embryonic tissues from each of the last three miscarriages by whole exome sequencing(WES)analysis.In addition,we generated a zebrafish line with a mutation homologous to the human EFTUD2 disruption to investigate the relationship between this mutation and RPL.We hypothesized that the mutation was associated with embryonic lethality,which may induce RPL in patients.The study was approved by the Medical Ethics Committee of the West China Second University Hospital,Sichuan University,China(No.2016[029]).Written informed consent was obtained from the couple before genetic testing. | Mei Yang Huaqin Sun Yanyan Liu Ting Hu | 2022 | Chinese Medical Journal2022，，9： | 1 |
| 14 | Melt index prediction by adaptively aggregated RBF neural networks trained with novel ACO algorithm显示文摘 | Jiubao Li Xinggao Liu Huaqin Jiang Yundu Xiao | 2011 | Journal of Applied Polymer Science2011，10，2： | 1 |
| 15 | One-step signal amplified lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A (BPA) in aqueous samples显示文摘 | Zhanlong Mei Wei Qu Yi Deng Huaqin Chu Jinxuan Cao Feng Xue Lei Zheng Hani Said El-Nezamic Yucheng Wu Wei Chen | 2013 | Biosensors and Bioelectronics2013，，： | 1 |
| 16 | Effects of fluoride additives on dehydrogenation behaviors of2LiBH4-MgH2system显示文摘 | KOU Huaqin XIAO Xuezhang LI Jinxiu | 2012 | Int J Hydrogen Energ2012，37，1： | 1 |
| 17 | Follistatin- related gene (FLRG) expression in human endometrium: Sex steroid hormones regulate the expression of FLRG in cultured human endometrial stromal cells clinical显示文摘 | HUAQIN WANG KOICHI TAKEBAYASHI KUNIHIRO TSUCHIDA | 2002 | Endocrinology & Metabolism2002，88，9： | 1 |
| 18 | Copper(1) chloride catalyzed crosscdhudrocoupling re - actions between silanes and ethynyl compounds, a new method for Ihe copolyme - rization of silanes and alkynes 显示文摘 | LIU HUAQIN HARROD JOHN F | 1990 | The research of Can J Chem1990，68，： | 1 |
| 19 | Novel G-pro- tein-coupled receptor-like proteins in the plant pathogenic fun- gus Magnaporthe grisea 显示文摘 | Kulkarni R D Thon M R Pan Huaqin | 2005 | Genome Biology2005，6，3： | 1 |
| 20 | Synthesis of Ti-containing mesoporous silicates from inorganic titanium sources显示文摘 | Huaqin Chu Ying Wan Dongyuan Zhao | 2009 | Catalysis Today2009，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员