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| 1 | Spinel + quartz-bearing ultrahigh-temperature granulites from Xumayao,Inner Mongolia Suture Zone,North China Craton:Petrology,phase equilibria and counterclockwise p-T path显示文摘在在北方中国 Craton 的内部蒙古缝术地区(IMSZ ) 以内的 Khondalite 带是为 Paleoproterozoic 的一个经典例子超离频温度(UHT ) 变态。这里,我们在 IMSZ 的南部的领域以内在 Xumayao 从一个新地区报导新忍受尖晶石的 metapelitic granulites。Petrological 研究并且尖晶石 + 的热力学的建模忍受石英的集合证明这些岩石以 UHT 条件经历了极端变态。尖晶石组织上发生在二背景:1 ) 高 XZn (Zn/(Mg +FeII + Zn )= 0.0710.232 ) 有在岩石矩阵的 perthitic K 长石,矽线石和石英的尖晶石;并且 2 ) 低 XZn (0.0450.070 ) 尖晶石作为在与石英和矽线石联合的石榴石 porphyroblasts 以内的包括。我们当模特儿的阶段 equilibria 在这些岩石的变形进化期间显示二个主要阶段: 1 )从 975 的在等压附近的冷却????畘慭慹?????????????朠慲畮楬整????????????????慲潴????????煥極楬牢慩?????????????胴?? | Huatian Zhang Jianghai Li Shoujie Liu Wenshan Li M. Santosh Honghao Wang | 2012 | Geoscience Frontiers2012，3，5： | 8 |
| 2 | Zircon U-Pb SHRIMP Ages from the Late Paleozoic Turpan-Hami Basin,NW China显示文摘二叠的暴烈的岩石广泛地在 Turpan-Hami 盆被散布,它是中央亚洲 orogenic 带的部分。这里我们为在井 Baocan 1 的流纹岩的现在的虾锆石数据,在盆的最深的井之一。283.9 牡慥? 桷捩 ? 慭湩祬挠湯楳瑳漠 ? 浳污 ? 湡 ? 敭楤浵猭穩摥猠慨汬睯氠湡獤楬敤 ? 湡 ? 潲正汳摩獥 ? 湡 ? 耶?湯猠整灥猠潬数 ?湡?潭湵慴湩瘠污敬獹?桔?慬杲獥?慬摮汳摩?湩畤散?祢?獵慨?慅瑲煨慵敫椠?桴?慇杮畯潴?慌摮汳摩?敤牢獩映潬?楷桴愠爠獥摩慵?潶畬敭漠?L畯?? | Xiang Mao Jianghai Li Huatian Zhang | 2014 | Journal of Earth Science2014，25，5： | 7 |
| 3 | Effect of hydroxyurea and etoposide on transduction of human bone marrow mesenchymal stem and progenitor cell by adeno-associated virus vectors显示文摘AIM: To study the effect of hydroxyurea and etoposide on transduction of human marrow mesenchymal and progenitor stem cells by adeno-associated virus (AAV). METHODS: Isolated human bone marrow mesenchymal stem and progenitor cells (hMSCs) were cultured in DMEM containing 10 % FBS or 5 % FBS and dexamethasone 1 μmol/L respectively. After being treated with hydroxyurea and etoposide, hMSCs were transduced by AAV-LUC. After two days luciferase activity (relative light unites per second or RLU/s) were tested, which indirectly reflected the relative transduction efficiency of different groups, and virus DNA was isolated by Hirt extraction for Southern hybridization. RESULTS: Transduction luciferase activity and transduction efficiency in cultures treated with hydroxyurea and etoposide were significantly higher than that in control cultures. Dividing cells had about 20-fold higher transduction efficiencycompared with control cells. Transduction efficiency in stationary cells was about 50 times higher than that in control cells. Southern analysis showed that hydroxyurea and etoposide enhanced second-strand DNA synthesis by rAAV. CONCLUSION: Hydroxyurea and etoposide could increase transduction efficiency of hMSCs by AAV vectors, and stationary cells were more sensitive to these drugs than dividing cells. | Xiao-dongJU Si-quanLOU Wei-guoWANG Jian-qiangPENG HuaTIAN | 2004 | Acta Pharmacologica Sinica2004，25，2： | 5 |
| 4 | Differentiation between intestial tubereu losis and Crohn's disease in endoscopic biopsy specimens by polymerage chain reaction显示文摘 | Huatian G Youqin C | 2002 | Am J Gastroenterel2002，97，6： | 1 |
| 5 | Differentiation between Intestinal Tubereulosis and Crohn's Disease in Endoscopic Biopsy Specimens by Polymerage Chain Reaction显示文摘 | Huatian G Youqin C | 2002 | Am J Gastroenterel2002，97，6： | 1 |
| 6 | Experiment study on micro-structure on different crystallographic planes of mc-Si etched in alkaline solution显示文摘The investigation of multi-crystalline silicon(mc-Si) surface etching technology is a key point in solar cell research.In this paper,mc-Si surface was etched in the common alkaline solution modified by an additive for 20 minutes at 78-80°C.Samples' surface morphology was observed by scanning electron microscope(SEM).It is firstly found that the etched mc-Si surface has the uniform distribution of trap pits although the morphologies of trap pits are slightly different on different crystallographic planes.Si(100) plane was covered with many small Si-mountain ranges or long V-shape channels arranged in a crisscross pattern.For(110) plane and(111) plane,they were full of a lot of triangle pit-traps(or quadrilateral holes) and twisted earthworm trap pits,respectively.The measured reflectance of the sample was 20.5% at wavelength range of 400-900 nm.These results illustrate that alkaline solution modified by an additive can effectively etch out trap pits with a good trapping light effect on mc-Si surfaces.This method should be very valuable for mc-Si solar cells. | WANG KunXia FENG ShiMeng XU HuaTian TIAN JiaTong YANG ShuQuan HUANG JianHua PEI Jun | 2012 | Science China(Technological Sciences)2012，55，6： | 1 |
| 7 | Analysis of Pragmatic Failure and College English Teaching显示文摘 | Aihua Pu Huatian Li | 2004 | Sino-US English Teaching2004，1，2： | 1 |
| 8 | Mapping QTLs for yield and nitrogen-related traits in wheat: influence of nitrogen and phosphorus fertilization on QTL expression显示文摘 | Yunfeng Xu Ruifang Wang Yiping Tong Huatian Zhao Qingen Xie Dongcheng Liu Aimin Zhang Bin Li Hongxing Xu Diaoguo An | 2014 | Theoretical and Applied Genetics2014，，1： | 1 |
| 9 | Taste mechanism of kokumi peptides from yeast extracts revealed by molecular docking and molecular dynamics simulation显示文摘Peptides have been used as flavors for decades,however,their tasting mechanism remains not entirely clear.In the present work,10 kokumi peptides identified in yeast extracts were selected as ligands.Their binding mechanism to calcium-sensitive receptors(CaSR)were investigated at molecular level by using molecular docking and molecular dynamics simulations.The results showed that all kokumi peptides could bind to CaSR to form complexes,of whichγ-Glu-Cys-Gly(GSH),γ-Glu-Leu(EL)andγ-Glu-Tyr(EY)being the top 3 peptides with higher affinity.Arg66,Ser147 and Ala168 may be the active sites of CaSR and interact with CaSR through hydrogen bonds;the different kokumi peptides and CaSR mainly rely on hydrogen bonding,electrostatic interaction and hydrophobic interaction to bind each other.This study provides a theoretical reference for the interaction between kokumi peptides and their receptors. | Jincui Chang Tao Feng Haining Zhuang Shiqing Song Min Sun Lingyun Yao Huatian Wang Feina Hou Jian Xiong Fan Li Pei Li Wenhui Zhu | 2022 | Journal of Future Foods2022，2，4： | 0 |
| 10 | The Lower Cretaceous Giant Dyke Swarms in the Arctic and Its Significance for linking of Siberia-Iceland Hot-Spot Track显示文摘Siberia-Iceland hot-spot track is the one of hot-spot track preserved on continent.Although this hot-spot track has clear plume'heads'-Siberia large igneous province,owing to thick continental lithosphere,its | LIU Zhonglan LI Jianghai ZHANG Huatian | 2016 | Acta Geologica Sinica(English Edition)2016，90，S1： | 0 |
| 11 | Analysis of RNA Recognition and Binding Characteristics of OsCPPR1 Protein in Rice显示文摘Pentatricopeptide repeat(PPR)proteins represent one of the largest protein families in plants and typically localize to organelles like mitochondria and chloroplasts.By contrast,CYTOPLASMLOCALIZED PPR1(OsCPPR1)is a cytoplasm-localized PPR protein that can degrade OsGOLDENLIKE1(OsGLK1)mRNA in the tapetum of rice anther.However,the mechanism,by which OsCPPR1 recognizes and binds to OsGLK1 transcripts,remains unknown.Through protein structure prediction and macromolecular docking experiments,we observed that distinct PPR motif structures of OsCPPR1 exhibited varying binding efficiencies to OsGLK1 RNA.Moreover,RNA-electrophoretic mobility shift assay experiment demonstrated that the recombinant OsCPPR1 can directly recognize and bind to OsGLK1 mRNA in vitro.This further confirmed that the mutations in the conserved amino acids in each PPR motif resulted in loss of activity,while truncation of OsCPPR1 decreased its binding efficiency.These findings collectively suggest that it may require some co-factors to assist in cleavage,a facet that warrants further exploration in subsequent studies. | ZHENG Shaoyan CHEN Junyu LI Huatian LIU Zhenlan LI Jing ZHUANG Chuxiong | 2024 | Rice science2024，31，2： | 0 |
| 12 | Global Mesozoic and Cenozoic Rift Systems: Constrain on the Tectonic Setting of Mafic Dyke Swarms显示文摘The primary tectonic setting of dyke swarms,especially those formed in the pre-Cambrian era,are under controversy(Peng et al.,2005).However,Mesozoic and Cenozoic rift systems,which are supposed to be | ZHANG Huatian LIU Jianghai LIU Zhonglan | 2016 | Acta Geologica Sinica(English Edition)2016，90，S1： | 0 |
| 13 | (Salen)osmium (Ⅵ) nitrides catalyzed glutathione depletion in chemotherapy显示文摘Glutathione depletion provides a promising strategy for the design of non-platinum anticancer drugs.Here we report a series of electrophilic (salen)osmium(Ⅵ) nitrides that react with glutathione to generate (salen)osmium(Ⅲ) ammine compounds.In vitro studies indicate that these osmium(VI) nitrides show comparable cytotoxicity to cisplatin against various carcinoma.Mechanistic studies with the representative compound[OsⅥ(N)(LH)(OH_(2))](PF6)(1,LH=N,N’-bis(salicylidene)-o-cyclohexyldiamine dianion) suggest that 1 induces glutathione depletion,reactive oxygen species generation,endoplasmic reticulum stress,and in turn triggers death receptor-mediated apoptosis and autophagy in lung cancer cells.In vivo evaluations show that 1 can inhibit tumor xenograft growth effectively with no body weight drop. | Wanqiong Huang Chen Pan Yongliang Huang Tao Huang Xiaonan Dong Yunzhou Chen Huatian Shi Taichu Lau Wailun Man Wenxiu Ni | 2023 | Chinese Chemical Letters2023，34，10： | 0 |
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