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| 1 | Synthesis and Photocatalytic Activity of Ti-pillared Bentonite显示文摘支柱 Ti 的火山灰成胶状黏土成功地用那能导致 TiO_2 支柱的转变从的一个修改方法被准备了对在低温度(150 deg C ) 的锐钛矿阶段非结晶。=1.94 nm 由支柱 Ti 的火山灰成胶状黏土获得了的 d_(001 ) 的价值比相应未加工的泥土(1.56 nm ) 的大。由于形成的大量 Ti 支柱,支柱 theTi 的火山灰成胶状黏土在吸附玫瑰精 B (RB ) 显示出一个优秀能力。photocatalyticactivity 和运动方程被在紫外照耀下面分解 RB 答案调查。支柱 Ti 的火山灰成胶状黏土显示出超级相片,这被发现为 RB 答案的降级的催化活动与未经治疗的火山灰成胶状黏土和纯 TiO_2 相比,并且 RB 答案的降级的运动方程是一个 1.5 颂诗方程。 | TANG Jianwen WU Pingxiao ZHENG Shaoyan LIU Yun WANG Feifei XIE Xianfa | 2006 | Acta Geologica Sinica(English Edition)2006,80,2: | 3 |
| 2 | Ecological principle meets cancer treatment: treating children with acute myeloid leukemia with low-dose chemotherapy显示文摘Standard chemotherapy regimens for remission induction of pediatric acute myeloid leukemia(AML) are associated with significant morbidity and mortality. We performed a cohort study to determine the impact of reducing the intensity of remission induction chemotherapy on the outcomes of selected children with AML treated with a low-dose induction regimen plus granulocyte colony stimulating factor(G-CSF)(low-dose chemotherapy(LDC)/G-CSF). Complete response(CR) after two induction courses was attained in 87.0%(40/46) of patients receiving LDC/G-CSF. Post-remission therapy was offered to all patients, and included standard consolidation and/or stem cell transplantation. During the study period, an additional 94 consecutive children with AML treated with standard chemotherapy(SDC) for induction(80/94(85.1%) of the patients attained CR after induction Ⅱ, P = 0.953) and post-remission. In this non-randomized study, there were no significant differences in 4-year event-free(67.4 vs. 70.7%;P = 0.99)and overall(70.3 vs. 74.6%, P = 0.69) survival in the LDC/G-CSF and SDC cohorts, respectively. After the first course of induction, recovery of white blood cell(WBC) and platelet counts were significantly faster in patients receiving LDC/G-CSF than in those receiving SDC(11.5 vs. 18.5 d for WBCs(P < 0.001);15.5 vs. 22.0 d for platelets(P < 0.001)). To examine the quality of molecular response, targeted deep sequencing was performed. Of 137 mutations detected at diagnosis in 20 children who attained hematological CR after two courses of LDC/G-CSF(n = 9) or SDC(n = 11), all of the mutations were below the reference value(variant allelic frequency <2.5%) after two courses, irrespective of the treatment group. In conclusion, children with AML receiving LDC/G-CSF appear to have similar outcomes and mutation clearance levels, but significantly lower toxicity than those receiving SDC. Thus, LDC/G-CSF should be further evaluated as an effective alternative to remission induction in pediatric AML. | Yixin Hu Aili Chen Xinchang Zheng Jun Lu Hailong He Jin Yang Ya Zhang Pinpin Sui Jingyi Yang Fuhong He Yi Wang Peifang Xiao Xin Liu Yinmei Zhou Deqing Pei Cheng Cheng Raul C. Ribeiro Shaoyan Hu Qian-fei Wang | 2019 | National Science Review2019,6,3: | 3 |
| 3 | National guidelines for diagnosis and treatment of thyroid cancer 2022 in China(English version)显示文摘Contents 1. Overview 2. Diagnosis and management 2.1 Screening for high-risk group 2.2 Clinical manifestations 2.2.1 Symptoms 2.2.2 Signs 2.2.3 Invasion and metastasis 2.3 Laboratory examination 2.3.1 Routine examination 2.3.2 Special examination 2.4 Imaging 2.4.1 Ultrasonography 2.4.2 Computed tomography (CT)2.4.3 Magnetic resonance imaging (MRI)2.4.4 Positron emission tomography (PET)-CT。 | 无 Shaoyan Liu Yansong Lin Yiming Zhu Lin Gui Xiaorong Hou Ziren Kong Yuanlin Piao Yuqing Sun Hao Wang Jian Wang Bo Zhang Ye Zhang Kun Zheng | 2022 | Chinese Journal of Cancer Research2022,34,3: | 2 |
| 4 | Comments on National guidelines for diagnosis and treatment of thyroid cancer 2022 in China (English version)显示文摘Thyroid cancer (TC) is the most common endocrine system cancer, of note, the overall survival of TC in China is suboptimal when comparing with the developed countries such as US (84.3%vs.98.3%), posing a great challenge among professionals involved in this field.Standardization of its diagnosis and treatment not only provides the basis for all the care givers to promote the entire level of TC management, but also is helpful in shortening the distance between China and other developed countries. A multidisciplinary team (MDT)should be involved in the comprehensive clinical management of TC, particularly for those advanced or refractory TC, which needs cooperation among members from ultrasonography, radiology, pathology, surgery. | Hao Wang Jian Wang Xiang Wang Yiming Zhu Yuqing Sun Xin Zhang Xiaorong Hou Kun Zheng Shaoyan Liu Yansong Lin | 2022 | Chinese Journal of Cancer Research2022,34,5: | 2 |
| 5 | Modeling ofatmosphere discharge in mixture of nitrogen and oxygen显示文摘 | Wang Yinan Cui Shaoyan Zheng Shu | 2011 | Frontier of Applied Plasma Technology2011,4,2: | 1 |
| 6 | Comparative analysis of window operating behavior in three different open-plan offices in Nanjing显示文摘Research on the window operating behavior of offices is of great significance for reducing building energy con-sumption and improving indoor comfort.The open-plan office is a common office form that involves a large number of people and a complex staffcomposition.The window operating behaviors in open-plan offices are also random and various.This study took three open-plan offices with different situations(area,office type,staffcomposition,etc.)as an example,which provides a new perspective on how people behave differently when opening or closing windows.The window operating behaviors in two typical seasons(summer and transition seasons)were recorded and analyzed.The occupants’schedules and influencing factors of window operating behavior were investigated by questionnaire surveys.In addition,the indoor environmental parameters,occu-pancy situation,and on-offstatuses of windows and air conditioning were acquired through field measurements.Furthermore,the differences in window operating behaviors in the three open-plan offices were compared from the perspectives of influencing factors,duration of the window on-offstatuses,and cause of window control ac-tions,among others.In addition,Spearman Correlation Coefficient was used to analyze the ranks of the candidate motivations for window operating behaviors.The preliminary results show that influenced by the personnel com-position,type of air conditioner and adjustable degree of windows,the window operating behaviors of different office buildings have larger discrepancies than that in the same building.However,there were some common characteristics in the window regulation behaviors of the three open-plan offices:they were generally influenced by the coupling of environmental factors,schedule factors,and equipment factors.This study reveals that when expand the research object from a single building to multiple buildings,more difficulties and challenges would be involved into behavior research. | Jiawen Ren Xin Zhou Jingjing An Da Yan Xing Shi Xing Jin Shaoyan Zheng | 2021 | Energy and Built Environment2021,2,2: | 0 |
| 7 | Analysis of RNA Recognition and Binding Characteristics of OsCPPR1 Protein in Rice显示文摘Pentatricopeptide repeat(PPR)proteins represent one of the largest protein families in plants and typically localize to organelles like mitochondria and chloroplasts.By contrast,CYTOPLASMLOCALIZED PPR1(OsCPPR1)is a cytoplasm-localized PPR protein that can degrade OsGOLDENLIKE1(OsGLK1)mRNA in the tapetum of rice anther.However,the mechanism,by which OsCPPR1 recognizes and binds to OsGLK1 transcripts,remains unknown.Through protein structure prediction and macromolecular docking experiments,we observed that distinct PPR motif structures of OsCPPR1 exhibited varying binding efficiencies to OsGLK1 RNA.Moreover,RNA-electrophoretic mobility shift assay experiment demonstrated that the recombinant OsCPPR1 can directly recognize and bind to OsGLK1 mRNA in vitro.This further confirmed that the mutations in the conserved amino acids in each PPR motif resulted in loss of activity,while truncation of OsCPPR1 decreased its binding efficiency.These findings collectively suggest that it may require some co-factors to assist in cleavage,a facet that warrants further exploration in subsequent studies. | ZHENG Shaoyan CHEN Junyu LI Huatian LIU Zhenlan LI Jing ZHUANG Chuxiong | 2024 | Rice science2024,31,2: | 0 |
| 8 | Genetic Diversity of Lotus(Nelumbo nucifera Gaertn.) Cultivars Revealed by ISSR Analysis显示文摘[Objectives] This study was conducted to investigate the genetic diversity of 20 lotus( Nelumbo nucifera Gaertn) samples. [Methods]On this optimal ISSR amplification system,16 primers were screened with good polymorphism,and the DNA was used to amplify the 20 plant samples. [Results] The 16 primers produced 225 loci,of which 170 were polymorphic,and the polymorphic loci percentage was up to 75. 56%. The genetic similarity coefficients between the 20 varieties ranged from 0. 577 8 to 0. 951 1,which were calculated by POPGENE32. The 20 varieties by UPMGA analysis could be clustered into 2 groups,the first of which included Baiyangdian red lotus and Donggua lotus,and other varieties was included in the second group. [Conclusions] ISSR molecular markers could be effectively used in genetic diversity and fingerprint analysis for different lotus varieties. | Tianyou HE Yinquan QU Shaoyan SHEN Xiaoyun MO Lingyan CHEN Yingjia LIU Jundong RONG Yushan ZHENG | 2017 | Agricultural Biotechnology2017,6,3: | 0 |
| 9 | CACA guidelines for holistic integrative management of thyroid cancer显示文摘Purpose:In recent years,thyroid cancer is a common clinical problem.Since guidelines for the diagnosis and treatment of thyroid nodules and diferentiated thyroid cancer were revised in 2012,signifcant scientifc advances have occurred in the feld.The aim of this guidelines is to inform clinicians,researchers,patients and health policy makers on published evidence and expert consensus relating to the diagnosis and management of thyroid malignancy.Methods:In order to better promote the clinical management of thyroid cancer in China,Chinese Association of Thyroid Oncology(CATO)organized relevant experts to write these guidelines based on latest relevant literatures and clinical experience of multiple centers.The specifc clinical issues and topics addressed in these guidelines were based on published evidence,prior versions of the Chinese guidelines and expert consensus.Results and conclusion:The guidelines provide recommendations for the management of diferent types of thyroid carcinoma,including papillary,follicular,medullary,and anaplastic carcinomas. | Minghua Ge Ming Gao Ruochuan Cheng Xiaohong Chen Haixia Guan Yansong Lin Shaoyan Liu Yu Wang Chuanming Zheng Xiangqian Zheng | 2022 | Holistic Integrative Oncology2022,1,1: | 0 |
| 10 | Predictors for Treatment Outcomes in Patients with Multi-drug Resistant Tuberculosis — China, 2018–2020显示文摘Summary What is already known about this topic?Multi-drug resistant tuberculosis(MDR-TB)is a critical global public health problem.What is added by this report?Sputum cultures and lung images show a strong association with treatment outcomes,serving as a multi-dimensional approach to identify MDR-TB patients with poor outcomes. | Shunxian Zhang Lei Qiu Dingzhong Wu Shaoyan Zhang Chenhui Pan Cui Li Heping Xiao Fuli Huang Hua Wang Feng Jiang Huiyong Zhang Peiyong Zheng Zhenhui Lu | 2022 | China CDC weekly2022,4,41: | 0 |
| 11 | Common Postzygotic Mutational Signatures in Healthy Adult Tissues Related to Embryonic Hypoxia显示文摘Postzygotic mutations are acquired in normal tissues throughout an individual’s lifetime and hold clues for identifying mutagenic factors.Here,we investigated postzygotic mutation spectra of healthy individuals using optimized ultra-deep exome sequencing of the time-series samples from the same volunteer as well as the samples from different individuals.In blood,sperm,and muscle cells,we resolved three common types of mutational signatures.Signatures A and B represent clocklike mutational processes,and the polymorphisms of epigenetic regulation genes influence the proportion of signature B in mutation profiles.Notably,signature C,characterized by C>T transitions at GpCpN sites,tends to be a feature of diverse normal tissues.Mutations of this type are likely to occur early during embryonic development,supported by their relatively high allelic frequencies,presence in multiple tissues,and decrease in occurrence with age.Almost none of the public datasets for tumors feature this signature,except for 19.6%of samples of clear cell renal cell carcinoma with increased activation of the hypoxia-inducible factor 1(HIF-1)signaling pathway.Moreover,the accumulation of signature C in the mutation profile was accelerated in a human embryonic stem cell line with drug-induced activation of HIF-1α.Thus,embryonic hypoxia may explain this novel signature across multiple normal tissues.Our study suggests that hypoxic condition in an early stage of embryonic development is a crucial factor inducing C>T transitions at GpCpN sites;and individuals’genetic background may also influence their postzygotic mutation profiles. | Yaqiang Hong Dake Zhang Xiangtian Zhou Aili Chen Amir Abliz Jian Bai Liang Wang Qingtao Hu Kenan Gong Xiaonan Guan Mengfei Liu Xinchang Zheng Shujuan Lai Hongzhu Qu Fuxin Zhao Shuang Hao Zhen Wu Hong Cai Shaoyan Hu Yue Ma Junting Zhang Yang Ke Qian-Fei Wang Wei Chen Changqing Zeng | 2022 | Genomics, Proteomics & Bioinformatics2022,20,1: | 0 |