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| 1 | A model and experimental study of phosphate uptake kinetics in algae:Considering surface adsorption and P-stress显示文摘Phosphorus is an important limiting nutrient in many ecosystems.Consequently,there is increasing interest on phosphate uptake and algal growth due to the increasing frequency and magnitude of algal blooms induced by eutrophication.The co-existence of surface adsorbed and intracellular phosphorus pools indicate that phosphate uptake by phytoplankton is,to some extent,a two-stage kinetic process.However,almost all previous uptake models considered the internal uptake stage only and ignored the possible impact of surface adsorption.In this article,a two-stage kinetic uptake model considering both surface adsorption and P-stress on phosphate uptake by algae was constructed and compared to conventional one-stage models,based on experimental data on short-term uptake kinetics of a green algae S.quadricauda.Results indicated that with suitable parameters,the two-stage uptake model not only fit the experimental data better,but also gave more reasonable and realistic explanations to the phosphate uptake process.The results are meaningful as surface-adsorption of phosphate may affect the uptake process of phosphate and assist in understanding realistic phosphate uptake kinetics in phytoplankton. | Bo Yao Beidou Xi Chunming Hu Shouliang Huo Jing Su Hongliang Liu | 2011 | Journal of Environmental Sciences2011，23，2： | 15 |
| 2 | Sirolimus-eluting cobalt-chromium stents: two-year dinical results from first-in-man study on the Firebird 2^TM stent显示文摘背景 Drug-eluting stents ( DES )被显示了显著地在冠的动脉疾病( CAD )的治疗减少临床的事件和 angiographic 狭窄 .This 学习被进行与 CAD.Methods 在病人的治疗估计基于聚合物的 sirolimus-eluting 钴铬鲜艳的小鸟 2TM stents 的长期的功效和安全这 first-in-man 研究用鲜艳的小鸟 2TM stent 是未来的、历史上控制的 multicenter 临床学习病人,它注册了 67 | XU Bo ZHANG Qi YANG Yue-jin QIAO Shu-bin ZHANG Rui-yan ZHANG Jian-sheng HU Jian QIN Xue-wen HONG Tao LI Jian-ping CHEN Ji-lin HUO Yong GAO Run-lin SHEN Wei-feng | 2008 | Chinese Medical Journal2008，，6： | 12 |
| 3 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 4 | Cell multiplication, apoptosis and p-Akt protein expression of bone mesenchymal stem cells of rat under hypoxia environment显示文摘Objective: To elucidate whether cell multiplication, apoptosis, glucose intake and p-Akt protein expression of bone Mesenchy-mal Stem Cells(MSCs) of rats is influenced by a hypoxic environment ex vivo. Methods: Passage 3 of bone marrow MSCs takenfrom Wistar rats, were cultured in a culturing chamber with 94%N2, 1%O2, 5%CO2 at 37℃. At different hypoxia time points, 0, 0.5,1, 4 and 8 h, glucose uptake was assayed by using radiation isotope 3H-G, Apoptotic Rate(AR) and dead rate(DR) were analyzedby flow cytometry(FCM) after Annexin V/PI staining, cell multiplication(by MTT methods) and p-Akt protein by immunocyto-chemistry and western blot. Results: Assay for CD29+, CD44+, CD71+, CD34- , Tn T+(after 5-azacytidine agent inducing) andALP+(after bone differentiation agent inducing) suggested these bone-derived cells were MSCs. The 3H-G intaking ratio(CPM/flask value: 157 ±11, 110 ±11, 107 ±13, 103 ±10, 100 ±9 and 98 ±10) of MSCs at different hypoxia time points, significantlydecreased compared to that of normoxia(P < 0.01) and tended to descend slowly with hypoxia time duration, for which there wasno statistical significance(P > 0.05). The AR(0.09 ±2.03%, 12.9 ±1.72%, 13.7 ±2.26%, 13.8 ±3.01%, 14.1 ±2.78% and 14.7 ±4.01% at 0, 0.5, 1, 4 and 8 h, respectively, P < 0.01) and DR (0.04 ±1.79%, 0.93 ±1.85%, 3.11 ±2.14%, 4.09 ±2.36%, 4.72 ±2.05% and 4.91 ±3.72% at 0, 0.5, 1, 4 and 8 h, respectively, P < 0.05) at different hypoxia time points significantly increasedcompared to those time in normoxia; The AR further went up with time (P < 0.05), however there was no statistical significance(P > 0.05) for the DR. Optical absorption value of MTT methods at different hypoxia time points significantly decreased com-pared to those with a corresponding normoxia time (P < 0.01) and degraded with time (in an hypoxic environment - P < 0.01).IOD of p-Akt protein of MSCs at different hypoxia time points significantly increased (0.367 ±0.031, 0.556 ±0.023, 0.579 ±0.013, 0.660 ±0.024, 0.685 ±0.039 and 0.685 ±0.011, respectively) compared to their equivalents in normoxia (P<0.05), how-ever, there was no statistical significance (P > 0.05) for different hypoxia time points. Hypoxia may result in ultramicrostructurechanges, such as defluvium of Microvilli, apoptotic body, 'margination'and so on and are further aggravated with hypoxia timestretching. Conclusion: Hypoxia may lead to a depression of MSCs intaking glucose, creep of cell multiplication, upregulation ofp-Akt protein and apoptosis of MSCs ex vivo. | Hongliang Kong Ningning Liu Xin Huo Bo Wang Haipeng Zhang Mingyu Gao Guoxian Qi | 2007 | Journal of Nanjing Medical University2007，21，4： | 10 |
| 5 | Chinese expert consensus on the non-invasive imaging examination pathways of stable coronary artery disease显示文摘 | Yun-Dai CHEN Wei-Yi FANG Ji-Yan CHEN Zhan-Ming FAN Chuan-Yu GAO Jun-Bo GE Zuo-Xiang HE Yong HUO Lang LI Si-Jin LI Xi-Lie LU Bin LV Ju-Ying QIAN Ya-Jun SHI Zhu-Jun SHEN Jing WANG Yi-Ning WANG Lei XU Li YANG Bo YU Mei ZHANG Jun-Jie YANG Shu-Yang ZHANG Xiao-Li ZHANG Shi-Hua ZHAO Yang ZHENG Yu-Chi HAN Guang ZHI | 2018 | Journal of Geriatric Cardiology2018，15，1： | 10 |
| 6 | PROGNOSIS OF UNPROTECTED LEFT MAIN CORONARY ARTERY STENTING AND THE FACTORS AFFECTING THE OUTCOMES IN CHINESE显示文摘 | GAO Run-lin XU Bo CHEN Ji-lin HAN Ya-ling LI Zhan-quan LUE Shu-zheng QI Xiao-yong HUO Yong WANG Le-feng CHEN Jun-zhu SHEN Wei-feng FANG Wei-yi JIA San-qing | 2006 | Chinese Medical Journal2006，，1： | 10 |
| 7 | Arch-dam crack deformation monitoring hybrid model based on XFEM显示文摘An extended finite element method incorporated with the cohesive crack model(CCM-based XFEM) is developed in consideration of crack tip enrichment.It could improve the accuracy and is introduced into dam safety monitoring for the first time.Firstly,the proposed method is verified for a benchmark concrete beam by comparing the results with those of numerical investigations obtained by other researchers.Furthermore,it is adopted as an alternative method for building the deformation hybrid models of non-stable cracks in an arc dam,for the reason that classical FEMs are cumbersome in modeling the cohesive crack growth due to the need of remeshing the moving discontinuities.Case study proves that the fitted results of the mentioned deformation hybrid model,better than the classical statistical model,are well consistent with the measured data and reliable to forecast the development tendency of crack deformation.Therefore,the present CCM-based XFEM could provide a practical way to simulate and monitor the cracking process in concrete arch dam. | ZHENG DongJian HUO ZhongYan LI Bo | 2011 | Science China(Technological Sciences)2011，54，10： | 9 |
| 8 | Development of database of real-world diesel vehicle emission factors for China显示文摘A database of real-world diesel vehicle emission factors, based on type and technology, has been developed following tests on more than 300 diesel vehicles in China using a portable emission measurement system. The database provides better understanding of diesel vehicle emissions under actual driving conditions. We found that although new regulations have reduced real-world emission levels of diesel trucks and buses significantly for most pollutants in China, NOx emissions have been inadequately controlled by the current standards, especially for diesel buses, because of bad driving conditions in the real world. We also compared the emission factors in the database with those calculated by emission factor models and used in inventory studies. The emission factors derived from COPERT(Computer Programmer to calculate Emissions from Road Transport) and MOBILE may both underestimate real emission factors, whereas the updated COPERT and PART5(Highway Vehicle Particulate Emission Modeling Software) models may overestimate emission factors in China. Real-world measurement results and emission factors used in recent emission inventory studies are inconsistent,which has led to inaccurate estimates of emissions from diesel trucks and buses over recent years. This suggests that emission factors derived from European or US-based models will not truly represent real-world emissions in China. Therefore, it is useful and necessary to conduct systematic real-world measurements of vehicle emissions in China in order to obtain the optimum inputs for emission inventory models. | Xianbao Shen Zhiliang Yao Qiang Zhang David Vance Wagner Hong Huo Yingzhi Zhang Bo Zheng Kebin He | 2015 | Journal of Environmental Sciences2015，27，5： | 8 |
| 9 | The Low Energy X-ray telescope (LE) onboard the Insight-HXMT astronomy satellite显示文摘The Low Energy X-ray telescope(LE) is one of the three main instruments of the Insight-Hard X-ray Modulation Telescope(Insight-HXMT). It is equipped with Swept Charge Device(SCD) sensor arrays with a total geometrical area of 384 cm^2 and an energy band from 0.7 to 13 ke V. In order to evaluate the particle induced X-ray background and the cosmic X-ray background simultaneously, LE adopts collimators to define four types of Field Of Views(FOVs), i.e., 1.6°×6°, 4°×6°, 50°-60°×2°-6 oand the blocked ones which block the X-ray by an aluminum cover. LE is constituted of three detector boxes(LEDs) and an electric control box(LEB) and achieves a good energy resolution of 140 e V@5.9 ke V, an excellent time resolution of 0.98 ms, as well as an extremely low pileup(<1%@18000 cts/s). Detailed performance tests and calibration on the ground have been performed,including energy-channel relation, energy response, detection efficiency and time response. | Yong Chen WeiWei Cui Wei Li Juan Wang YuPeng Xu FangJun Lul YuSa Wang TianXiang Chen DaWei Han Wei Hu Yi Zhang Jia Huo YanJi Yang MaoShun Li Bo Lu ZiLiang Zhang TiPei Li ShuangNan Zhang ShaoLin Xiong Shu Zhang RongFeng Xue XiaoFan Zhao Yue Zhu YuXuan Zhu HongWei Liu YiJung Yang Fan Zhang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 8 |
| 10 | Efficacy and safety of FIREHAWK abluminal groove filled biodegradable polymer sirolimus-eluting stents for the treatment of long coronary lesions: nine-month angiographic and one-year clinical results from TARGET I trial lona cohort显示文摘 | XU Bo GAO Run-lin ZHANG Rui-yan WANG Hai-chang LI Zhan-quan YANG Yue-jin MA Chang-sheng HAN Ya-ling Alexandra J. Lansky HUO Yong LI Wei Martin B. Leon | 2013 | Chinese Medical Journal2013，，6： | 8 |
| 11 | Antioxidant Effect of Human Selenium-containing Single-chain Fv in Rat Cardiac Myocytes显示文摘Reactive oxygen species(ROS) plays a key role in human heart diseases. Glutathione peroxidase(GPX) functions as an antioxidant as it catalyzes the reduction of hydroperoxide. In order to investigate the antioxidant effect of human selenium-containing single-chain Fv(Se-scFv-B3), a new mimic of GPX, a model system of hydrogen peroxide(H2O2)-induced rat cardiac myocyte damage was established. The cardiac myocyte damage was characterized in terms of cell viability, lipid peroxidation, cell membrane integrity, and intracellular H2O2 level. The Se-scFv-B3 significantly reduced H2O2-induced cell damage as shown by the increase of cell viability, the decline of malondialdehyde(MDA) production, lactate dehydrogenase(LDH) release, and intracellular H2O2 level. So Se-scFv-B3 may have a great potential in the treatment of human heart diseases induced by ROS. | HUO Rui SHI Yi XU Jun-jie YAN Fei LV Shao-wu SU Jia-ming DUAN Yu-jing FAN Jia NING Bo CONG Deng-li YAN Gang-lin LUO Gui-min WEI Jing-yan | 2009 | Chemical Research in Chinese Universities2009，25，2： | 8 |
| 12 | Nine-month angiographic and two-year clinical follow-up of polymer-free sirolimus-eluting stent versus durable-polymer sirolimus-eluting stent for coronary artery disease: the Nano randomized trial显示文摘 | Zhang Yaojun Chen Fang Takashi Muramatsu Xu Bo Li Zhanquan Ge Junbo He Qing Yang Zhijian Li Shumei Wang Lefeng Wang Haichang He Ben Li Kang Qi Guoxian Li Tianchang Zeng Hesong Peng Jianjun Jiang Tieming Zeng Qiutang Zhu Jianhua Fu Guosheng Christos V. Bourantas Patrick W. Serruys Huo Yong | 2014 | Chinese Medical Journal2014，，11： | 8 |
| 13 | Sirolimus-eluting cobalt alloyed stents in treating patients with coronary artery disease:six-month angiographic and one-year clinical follow-up result A prospective,historically controlled,multi-center clinical study显示文摘drug-eluting stents ( DES )的出现戏剧性地减少了的背景 in-stent restenosis.This 学习的发生被进行为与冠的动脉 disease.Methods 对待病人评估 sirolimus-eluting 钴铬 stents (鲜艳的小鸟 2 )的 safetyand 功效有冠的损害被选择收到鲜艳的小鸟的 de novo 或 non-stented restenostic 的 57 个病人是的 2 stent 最后的治疗(鲜艳的小鸟 2 组)。另一 49 个连续病人与赤裸的钴 alloyed stents 被植入(司机, Medtronic )时髦以前的六个月和服务同样历史的控制(控制组) .Baseline 临床的特征, angiographic 特征,程序的结果,30天,关于主要不利心脏的事件(向)的出现的6月、12月的临床的后续,以及主要端点近来,在6月的 angiographic 后续的腔损失在二 groups.Results 之间被比较 demog 在鲜艳的小鸟 2 组,参考容器的吝啬的直径更小((2.79 ? , | ZHANG Qi XU Bo YANG Yue-jin ZHANG Rui-yan LI Jian-ping QIAO Shu-bin ZHANG Jian-sheng HU Jian QIN Xue-wen HONG Tao CHEN Ji-lin HUO Yong SHEN Wei-feng GAO Run-lin | 2007 | Chinese Medical Journal2007，，7： | 8 |
| 14 | Effects of serum of the rats ventilated with high tidal volume on endothelial cell permeability and therapeutic effects of ulinastatin显示文摘有在对待非常有病的病人,的通风机的普遍使用的背景导致通风机的肺损害(VILI ) 的病态因此正在增加。VILI 被煽动性的过程的微脉管的泄漏和激活的可观的增加描绘。在这研究,我们在 VILI 老鼠浆液 onendothelial 细胞骨架和单层调查了煽动性的调停人的效果细胞的渗透,以及治疗学的效果 ofulinastatin,由 VILI 导致了探索在简历损伤和肺水肿之间的致病和关系。三十只健康男 Sprague-Dawley 老鼠随机被划分成三个组的方法:组 A (正常潮汐的体积通风) ,组 B (高潮汐的体积通风) 和 groupC (加 ulinastatin 的高潮汐的体积通风) 。在通风以后的每只老鼠的浆液被加到为二个小时中等的 endothelial 房间线 ECV-304 在 endothelial 上观察浆液 and/orulinastatin 的效果含纤维的肌动朊和渗透。比作老鼠的结果与正常潮汐的体积通气了,老鼠的浆液与与一在产生的中心在外部细丝乐队和长、厚的压力纤维的形成变弱荧光灯的紧张引起肌动朊细胞骨架的一个惹人注目的重组的高潮汐的体积通气了 inendothelial 收缩和更高的渗透。有 ulinastatin 的优先的处理显著地减少了上述变化。在组 A, B 或 C 老鼠浆液刺激以后的 endothelial 渗透的渗透系数的变化是(6.95 ± 1.66 )% ,(27.50 ± 7 .77 )% 并且(17.71 ± 4 .66 )% 分别地与统计上重要的差别(P <
0.05 ) 在三个组之中。结论专业版在老鼠的浆液的煽动性的调停人由重新组织肌动朊细胞骨架的给定的高潮汐的卷通风增加 endothelial 渗透,和有 ulinastatin 的预告的处理由专业版禁止煽动性的调停人减少渗透。 | HUO Guo-dong CAI Shao-xi CHEN Bo CHEN Ying-hua | 2006 | Chinese Medical Journal2006，，16： | 7 |
| 15 | A prospective multicenter parallel-controlled trial of TIVOLI biodegradable-polymer-based sirolimus-eluting stent compared to ENDEAVOR zotarolimus-eluting stent for the treatment of coronary artery disease: 8-month angiographic and 2-year clinical follow-up results显示文摘背景可得到的 drug-eluting stents (DES ) 在减少狭窄率获得了大成功。最近,调查者证明了持久的聚合物搬运人在愈合的 DES 相关的过分敏感的反应和延期容器起一个重要作用。TIVOLI stent 是新奇 sirolimus-eluting 有可被细菌破坏的涂层包含的冠的 stent sirolimus 和 polylactic-co-glycolic 酸(PLGA ) 聚合物。现在的学习寻求了在与冠的动脉 disease.Methods A 对待病人评估 TIVOLI biodegradable-polymer-based sirolimus-eluting stent 的有效性和安全未来, multicenter 有努力 zotarolimus-eluting stent 的临床的试用比较 TIVOLI 可被细菌破坏的涂的 sirolimus-eluting stent 在 324 个病人被进行(TIVOLI 组:168 个病人;努力 group:156 病人) 在中国在 12 点集中晚表明 in-stent 的非低劣有与在有二个 de novo 土著人的最大值的题目的努力 stent 相比的 TIVOLI stent 的损失冠的动脉损害(损害长度 40 公里,参考容器直径 2.25-4.00 公里) 。主要结束点晚是 angiographic in-stent 损失在 8 月。第二等的结束点是在 2 年的临床的结果,包括主要不利心脏的事件(心脏的死亡,心肌的梗塞,或目标损害 revascularization ) ,在在 TIVOLI 组的 8 个月的 stent thrombosis.Results Angiographic 迟了的腔损失比 ENDEAVOR 组优异(in-stent (0.25 眠獡爠摥 ' 讚??? | XU Bo DOU Ke-fei HAN Ya-ling LU Shu-zheng YANG Yue-jin HUO Yong WANG Le-feng CHEN Yun-dai WANG Hai-chang LI Wei-min CHEN Ji-yan WANG Lei WANG Yong GE Jun-bo LI Wei GAO Run-lin | 2011 | Chinese Medical Journal2011，，6： | 6 |
| 16 | Investigation of long-term implantation of BuMA stent in a porcine coronary model显示文摘 | CHEN Ming WANG Xin-gang ZHENG Bo PENG Hong-yu Zhang Xiao-yan ZHANG Bin HUO Yong | 2012 | Chinese Medical Journal2012，，22： | 6 |
| 17 | Value of urine IL-8, NGAL and KIM-1 for the early diagnosis of acute kidney injury in patients with ureteroscopic lithotripsy related urosepsis显示文摘Purpose::To investigate the clinical value of urine interleukin-18(IL-8),neutrophil gelatinase-associated lipocalin(NGAL)and kidney injury molecule-1(KIM-1)for the early diagnosis of acute kidney injury(AKI)in patients with ureteroscopic lithotripsy(URL)related urosepsis.Methods::A retrospective study was carried out in 157 patients with urosepsis after URL.The patients were divided into AKI group and non-AKI group according to the Kidigo guideline and urine IL-8,NGAL and KIM-1 levels were detected by enzyme-linked immunosorbent assay at 0,4,12,24 and 48 h after the surgery.Receiver operating characteristic curve(ROC)was used to evaluate the diagnostic value of these three biomarkers for postoperative AKI.Results::The level of urine IL-8,NGAL and KIM-1 in AKI group was significantly higher than that in non-AKI group at 4,12,24 and 48 h(p<0.01).The ROC analysis showed the combined detection of urine IL-8,NGAL and KIM-1 at 12 h had a larger area under curve(AUC)than a single marker(0.997,95%CI:0.991-0.998),and the sensitivity and specificity were 98.2%and 96.7%,respectively.Pearson correlation analysis showed that the levels of urine NGAL at 4,12,24 and 48 h in AKI patients were positively correlated with the levels of urine KIM-1 and IL-18(p<0.01).Conclusion::AKI could be quickly recognized by the elevated level of urine IL-8,NGAL and KIM-1 in patients with URL-related urosepsis.Combined detection of the three urine biomarkers at 12 h after surgery had a better diagnostic performance,which may be an important reference for the early diagnosis of AKI. | Dan Tan Liang Zhao Wei Peng Fang-Hao Wu Guo-Bin Zhang Bo Yang Wen-Qian Huo | 2022 | Chinese Journal of Traumatology2022，25，1： | 6 |
| 18 | Two Cases of Multi-antibiotic Resistant Cronobacter spp. Infections of Infants in China*显示文摘Infections by Cronobacter spp. are hazardous to infants since they can lead to neonatal meningitis, bacteremia, and necrotizing enterocolitis. Cronobacter spp. are frequently resistant to β-lactam derivatives, macrolides, and aminoglycosides. In addition, multi-resistant strains have also been detected. In China, the isolation rate of Cronobacter spp. from commercial powdered infant formula(PIF) or follow-up formula(FUF) is relatively high. Nevertheless, clinical cases of Cronobacter infection have been ignored to date. Here we describe two cases of Cronobacter infection detected at the Wuhan Women and Children Medical Care Center Hospital(Wuhan City, China). We provide the genomic analysis of the isolates and the antibiotic-resistance profiles of the two strains. The Cronobacter strains identified in this study were not susceptible to third-generation cephalosporins, aminoglycoside, and/or trimethoprim-sulfamethoxazole. Whole genome sequencing revealed various genes known to encode antibiotic resistance. Future studies are needed to determine whether the genes predicted in this study are functional. As with Enterobacter spp., the antibiotic resistance of Cronobacter is a serious issue that requires more attention. | CUI Jing Hua YU Bo XIANG Yun ZHANG Zhen ZHANG Ting ZENG Ying Chun CUI Zhi Gang HUO Xi Xiang | 2017 | Biomedical and Environmental Sciences2017，30，8： | 6 |
| 19 | Surface Electrical Field Distribution Simulation and Insulation Characteristics Test of Polluted Insulators显示文摘In this paper,the electrical fields along the insulator surface under different scenarios,such as asymmetric pollution on top/bottom surface,and uneven circumferential distribution of surface pollution,have been calculated with finite element method for field simulation.Tests on artificial pollution insulators are conducted to study the 50% withstand voltage U50 of artificial pollution suspension insulators under different NSDD(non-soluble deposit density)and asymmetric pollution on the top/bottom surface,and study the change of leakage current with air humidity under different voltage and different ESDD(equivalent salt deposit density).The result shows that asymmetric top/bottom surface pollution has a greater impact on the insulator electrical field distribution,and the leakage current will jump under low air humidity,if had large ESDD,which has practical meanings to the anti-pollution design of the transmission line under different pollution levels across the country. | HUO Feng CHEN Yong CAI Wei DING Yi-zheng GAO Bo ZHANG Qiao-gen | 2008 | 高电压技术2008，34，12： | 6 |
| 20 | Assessment of FY-4A and Himawari-8 Cloud Top Height Retrieval through Comparison with Ground-Based Millimeter Radar at Sites in Tibet and Beijing显示文摘The accuracy of passive satellite cloud top height (CTH) retrieval shows regional dependence. This paper assesses the CTH derived from the FY-4A and Himawari-8 satellites through comparison with those from the ground-based millimeter radar at two sites: Yangbajing, Tibet, China (YBJ), and the Institute of Atmospheric Physics (IAP), Beijing, China. The comparison shows that Himawari-8 missed more CTHs at night than FY-4A, especially at YBJ. It is found that the CTH difference (CTHD;radar CTH minus satellite CTH) for FY-4A and Himawari-8 is 0.06 ± 1.90 km and −0.02 ± 2.40 km at YBJ respectively, and that is 0.93 ± 2.24 km and 0.99 ± 2.37 km at IAP respectively. The discrepancy between the satellites and radar at IAP is larger than that at YBJ. Both satellites show better performance for mid-level and low-level clouds than for high-level clouds at the two sites. The retrievals from FY-4A agree well with those from Himawari-8, with a mean difference of 0.08 km at YBJ and 0.06 km at IAP. It is found that the CTHD decreases as the cloud depth increases at both sites. However, the CTHD has no obvious dependence on cloud layers and fractions. Investigations show that aerosol concentration has little impact on the CTHD. For high and thin clouds, the CTHD increases gradually with the increase of the surface temperature, which might be a key factor causing the regional discrepancy between IAP and YBJ. | Bo LIU Juan HUO Daren LYU Xin WANG | 2021 | Advances in Atmospheric Sciences2021，38，8： | 5 |
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