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4篇 您的检索式:作者名="ISAO MOMOSE"
    题名 作者 年代 出处 被引量
1A New Method for the Evaluation of Vaccine Safety Based on Comprehensive Gene Expression Analysis显示文摘Haruka Momose Takuo Mizukami Masaki Ochiai Isao Hamaguchi Kazunari Yamaguchi Yongqun Oliver He 2010Journal of Biomedicine and Biotechnology2010,,:1
2An improved abnormal toxicity test by using reference vaccine-specific body weight curves and histopathological data for monitoring vaccine quality and safety in Japan显示文摘Takuo Mizukami Atsuko Masumi Haruka Momose Madoka Kuramitsu Kazuya Takizawa Seishiro Naito Jun-ichi Maeyama Keiko Furuhata Momoka Tsuruhara Isao Hamaguchi Kazunari Yamaguchi 2008Biologicals2008,,1:1
3Mitochondrial inhibitors show preferential cytotoxicity to human pancreatic cancer PANC-1 cells under glucose-deprived conditions显示文摘Isao Momose Shun-ichi Ohba Daisuke Tatsuda Manabu Kawada Tohru Masuda Go Tsujiuchi Takao Yamori Hiroyasu Esumi Daishiro Ikeda 2010Biochemical and Biophysical Research Communications2010,,3:1
4Deoxynortryptoquivaline:A unique antiprostate cancer agent显示文摘The androgen receptor (AR) is a critical target in all the clinical stages of prostate cancer. To identify a new ARinhibitor, we constructed a new screening system using the androgen-dependent growth of prostate cancer cell lines as ascreening indicator. We screened 50,000 culture broths of microorganisms using this screening system and found that thefermentation broth produced by a fungus inhibited androgen-dependent growth of human prostate cancer LNCaP cellswithout cytotoxicity. Purification of this culture medium was performed, and this resulted in deoxynortryptoquivaline(DNT) being identified as a novel inhibitor of AR function. DNT showed potent inhibition of androgen-dependentgrowth of human prostate cancer LNCaP cells. The AR competitor assay was performed, and DNT did not act as anAR antagonist. However, DNT inhibited AR-dependent transcriptional activity and AR nuclear translocation, itsuggested that the suppression of AR function leads to inhibition activity against androgen-dependent growth.YOHKO YAMAZAKI MANABU KAWADA ISAO MOMOSE 2023Oncology Research2023,31,6:0
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