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| 1 | Relationship of lipid oxidation with subclinical atherosclerosis and 10-year coronary events in general population显示文摘 | Miquel Gómez Joan Vila Roberto Elosua Lluís Molina Jordi Bruguera Joan Sala Rafel Masià Maria Isabel Covas Jaume Marrugat Montserrat Fitó | 2014 | Atherosclerosis2014，，1： | 1 |
| 2 | Integrated treatment of combined sewer wastewater and stormwater in a hybrid constructed wetland system in southern Spain and its further reuse显示文摘 | Cristina ávila Juan José Salas Isabel Martín Carlos Aragón Joan García | 2012 | Ecological Engineering2012，，： | 1 |
| 3 | Rapidly Progressive Dementia: Experience in a Tertiary Care Medical Center显示文摘 | Isabel Sala Marta Marquié Ma. Belén Sánchez-Saudinós Raquel Sánchez-Valle Daniel Alcolea Beatriz Gómez-Ansón Teresa Gómez-Isla Rafael Blesa Alberto Lleó | 2012 | Alzheimer Disease & Associated Disorders2012，，3： | 1 |
| 4 | Chemoembolization of hepatocellular carcinoma with drug eluting beads: Efficacy and doxorubicin pharmacokinetics显示文摘 | María Varela María Isabel Real Marta Burrel Alejandro Forner Margarita Sala Mercé Brunet Carmen Ayuso Lluis Castells Xavier Monta?á Josep M. Llovet Jordi Bruix | 2007 | Journal of Hepatology2007，，3： | 1 |
| 5 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 6 | Chemoembolization of hepatocellular carcinoma with drug eluting beads: Efficacy and doxorubicin pharmacokinetics显示文摘 | María Varela María Isabel Real Marta Burrel Alejandro Forner Margarita Sala Mercé Brunet Carmen Ayuso Lluis Castells Xavier Monta?á Josep M. Llovet Jordi Bruix | 2007 | Journal of Hepatology2007，，3： | 1 |
| 7 | A Randomized Trial of Circumferential Pulmonary Vein Ablation Versus Antiarrhythmic Drug Therapy in Paroxysmal Atrial Fibrillation显示文摘 | Carlo Pappone Giuseppe Augello Simone Sala Filippo Gugliotta Gabriele Vicedomini Simone Gulletta Gabriele Paglino Patrizio Mazzone Nicoleta Sora Isabelle Greiss Andreina Santagostino Laura LiVolsi Nicola Pappone Andrea Radinovic Francesco Manguso Vincenzo | 2006 | Journal of the American College of Cardiology2006，，11： | 1 |
| 8 | Chemoembolization of hepatocellular carcinoma with drug eluting beads: Efficacy and doxorubicin pharmacokinetics显示文摘 | María Varela María Isabel Real Marta Burrel Alejandro Forner Margarita Sala Mercé Brunet Carmen Ayuso Lluis Castells Xavier Monta?á Josep M. Llovet Jordi Bruix | 2007 | Journal of Hepatology2007，，3： | 1 |
| 9 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 10 | Chemoembolization of hepatocellular carcinoma with drug eluting beads: Efficacy and doxorubicin pharmacokinetics显示文摘 | María Varela María Isabel Real Marta Burrel Alejandro Forner Margarita Sala Mercé Brunet Carmen Ayuso Lluis Castells Xavier Monta?á Josep M. Llovet Jordi Bruix | 2007 | Journal of Hepatology2007，，3： | 1 |
| 11 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 12 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 13 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 14 | Prevalence of Symptomatic and Asymptomatic Peripheral Arterial Disease and the Value of the Ankle-brachial Index to Stratify Cardiovascular Risk显示文摘 | R. Ramos M. Quesada P. Solanas I. Subirana J. Sala J. Vila R. Masiá C. Cerezo R. Elosua M. Grau F. Cordón D. Juvinyà M. Fitó M. Isabel Covas A. Clarà M. ángel Mu?oz J. Marrugat | 2009 | European Journal of Vascular & Endovascular Surgery2009，，3： | 1 |
| 15 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 16 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 17 | Expression of Cocaine-Evoked Synaptic Plasticity by GluN3A-Containing NMDA Receptors显示文摘 | Tifei Yuan Manuel Mameli Eoin C. O’ Connor Partha Narayan Dey Chiara Verpelli Carlo Sala Isabel Perez-Otano Christian Lüscher Camilla Bellone | 2013 | Neuron2013，，4： | 1 |
| 18 | Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia显示文摘Background:Astrocytes play an essential role in neuroinflammation and are involved in the pathogenesis of neurodenegerative diseases.Studies of glial fibrillary acidic protein(GFAP),an astrocytic damage marker,may help advance our understanding of different neurodegenerative diseases.In this study,we investigated the diagnostic performance of plasma GFAP(pGFAP),plasma neurofilament light chain(pNfL)and their combination for frontotemporal dementia(FTD)and Alzheimer's disease(AD)and their clinical utility in predicting disease progression.Methods:pGFAP and pNfL concentrations were measured in 72 FTD,56 AD and 83 cognitively normal(CN)participants using the Single Molecule Array technology.Of the 211 participants,199 underwent cerebrospinal(CSF)analysis and 122 had magnetic resonance imaging.We compared cross-sectional biomarker levels between groups,studied their diagnostic performance and assessed correlation between CSF biomarkers,cognitive performance and cortical thickness.The prognostic performance was investigated,analyzing cognitive decline through group comparisons by tertile.Results:Unlike pNfL,which was increased similarly in both clinical groups,pGFAP was increased in FTD but lower than in AD(all P<0.01).Combination of both plasma markers improved the diagnostic performance to discriminate FTD from AD(area under the curve[AUC]:combination 0.78;pGFAP 0.7;pNfL 0.61,all P<0.05).In FTD,pGFAP correlated with cognition,CSF and plasma NfL,and cortical thickness(all P<0.05).The higher tertile of pGFAP was associated with greater change in MMSE score and poor cognitive outcome during follow-up both in FTD(1.40 points annually,hazard ratio[HR]3.82,P<0.005)and in AD(1.20 points annually,HR 2.26,P<0.005).Conclusions:pGFAP and pNfL levels differ in FTD and AD;and their combination is useful for distinguishing between the two diseases.pGFAP could also be used to track disease severity and predict greater cognitive decline during follow-up in patients with FTD. | Nuole Zhu Miguel Santos-Santos Ignacio lllán-Gala Victor Montal Teresa Estellés Isabel Barroeta Miren Altuna Javier Arranz Laia Muñoz Olivia Belbin Isabel Sala Maria Belén Sánchez-Saudinós Andrea Subirana Laura Videla Jordi Pegueroles Rafael Blesa Jordi Clarimón Maria Carmona-Iragui Juan Fortea Alberto Lleó Daniel Alcolea | 2021 | Translational Neurodegeneration2021，10，4： | 0 |
| 19 | Multi-tissue transcriptomics of a unique monozygotic discordant twin case of severe progressive osseous heteroplasia显示文摘Progressive osseous heteroplasia(POH)is an ultra-rare autosomal dominant disabling disorder characterized by heterotopic ossification(HO).It is caused by heterozygous inactivating mutations in the GNAS(guanine nucleotide-binding protein alpha-stimulating activity polypeptide)gene.However,the molecular mechanisms underlying HO remain poorly understood.As a treatment for POH is not yet available,the identification of the mechanisms driving POH in affected tissues using gene expression may be of great help to underestand the molecular basis of POH and develop new therapeutic approaches. | Alberto Gomez-Carballa Maria Jose Curras-Tuala Sara Pischedda Miriam Cebey-Lopez Jose Gomez-Rial Irene Rivero-Cale Jacobo Pardo-seco Xabier Bello Sandra Viz-Lasheras Antonio Justicia-Grande Julian Montoto-Louzao Alba Camino-Mera Isabel Ferreiros-Vidal Maximo Fraga Jose RAntunez Rodolfo Gomez Federico Martinon-Torres Antonio Salas | 2024 | Genes & Diseases2024，11，3： | 0 |
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