|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Hypothetical model of dynamic biomarkers of the Alzheimer’s pathological cascade显示文摘 | Clifford R Jack David S Knopman William J Jagust Leslie M Shaw Paul S Aisen Michael W Weiner Ronald C Petersen John Q Trojanowski | 2010 | Lancet Neurology2010，，1： | 4 |
| 2 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 3 | Increasing diabetes self-management education in community settings显示文摘 | Susan L Norris Phyllis J Nichols Carl J Caspersen Russell E Glasgow Michael M Engelgau Leonard Jack Susan R Snyder Vilma G Carande-Kulis George Isham Sanford Garfield Peter Briss David McCulloch | 2002 | American Journal of Preventive Medicine2002，，4： | 2 |
| 4 | Lipopolysaccharidebinding protein is required to combat a murine gram-negative bacterialinfection显示文摘 | Jack R S Fan X Bernheiden M | 1997 | Nature1997，389，6652： | 1 |
| 5 | Biological souring and mitigation in oil reservoirs 显示文摘 | Gieg L M Jack T R Foght J M | 2011 | Applied Microbiology and Biotechnology2011，92，2： | 1 |
| 6 | Peripheral neuropathy and the risk of cardio- vascularevents in type 2 diabetes mellitus显示文摘 | Jack R W Brownrigg Matthew M Thompson 1 Kausik K Ray | 2014 | Cardiac risk factors and prevention2014，，100： | 1 |
| 7 | Urinary bladder smooth muscle sngineered from adipose stem ceils and a three dimensional synthetic composite 显示文摘 | Jack GS Zhang R Lee M | 2009 | Biomaterials2009，30，19： | 1 |
| 8 | Molecular mechanism of lung cancer显示文摘 | DEVEREUX M S JACK A | 1996 | Chest1996，109，1： | 1 |
| 9 | Chain scission resists for extreme ultra violet lithography based on high performance polysulfonecontaining polymers显示文摘 | Lawrie K J Blakey I Blinco J P Cheng H H Gronheid R Jack K S Pollentier I Leeson M J Younkin T R Whittaker A K | 2011 | Journal of Materials Chemistry2011，21，： | 1 |
| 10 | Radix-2 FFT butterfly processor using distributed arithmetic显示文摘 | Mactaggart I R Jack M A | 1983 | Electronics Letters1983，19，2： | 1 |
| 11 | Simultaneous tracheal and oesophageal pH measurement in asthmatic patients with gastroesophageal reflux显示文摘 | Jack C I Calverley P M Donnelly R J | 1995 | Thorax1995，50，2： | 1 |
| 12 | Low erythrocyte complement receptor type 1 (CR1, CD35) expression in preeclamptic gestations 显示文摘 | FEINBERG B B JACK R M MOK S C | 2005 | Am J Reprod Immunol2005，54，6： | 1 |
| 13 | Comparative mieroarray analysis and pulmonary changes in brown norway rats exposed to ovalbumin and concentrated air particulates 显示文摘 | Brooke L H David M R Jack R H | 2009 | Toxicological Sciences2009，108，： | 1 |
| 14 | Impaired microRNA processing enhances cellular transformation and tumorigenesis显示文摘 | Kumar M S Lu J Mercer K L Golub T R Jacks T | 2007 | Nat Genet2007，39，： | 1 |
| 15 | Introduction to the recom- mendations from the National Institute on Aging-Alzheimer's Associa- tion workgroups on diagnostic guidelines for Alzheimer's disease显示文摘 | Jack C R Jr Albert M S Knopman D S | 2011 | Alzheimers Dement2011，7，3： | 1 |
| 16 | The effects of peer feedback on team member behavior显示文摘 | Peter G D Richard R R Jack W M | 1997 | Group and Organization Management1997，22，4： | 1 |
| 17 | The Alzheimer’s disease neuroimaging initiative: progress report and future plans显示文摘 | Weiner M W Aisen P S Jack C R Jr | 2010 | Alzheimers Dement2010，6，3： | 1 |
| 18 | Urinary bladder smooth muscle engineered from adipose stem cells and a three dimensional synthetic composite 显示文摘 | Jack GS Zhang R Lee M | 2009 | Biornaterials2009，30，19： | 1 |
| 19 | Fast clustering algorithm for vector quantization显示文摘 | Pan J S Mclnnes F R Jack M A | 1996 | Pattern Recognition1996，29，3： | 1 |
| 20 | Microarray-based detection of viruses causing vesicular or vesicular-like lesions in livestock animals显示文摘 | Jack P J M Amos-Ritchie R N Reverter A | 2009 | Vet Microbiol2009，133，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员