|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Anatomical variation of infra-pyloric artery origination: A prospective multicenter observational study (IPA-Origin)显示文摘Objective: Infra-pyloric artery(IPA) is an important anatomical landmark in treatment of gastric cancer and is the key vessel for pylorus-preserving gastrectomy and subgroup of infra-pyloric lymph nodes. However, its anatomical variation is not thoroughly understood. Our study aimed to clarify the origination of the IPA.Methods: We did this prospective, multicenter, open-label, observational study at gastric surgery departments of34 hospitals in China. Gastric cancer patients aged 18 years or older and scheduled to undergo elective total or distal gastrectomy were assigned. During the surgery, IPA dissecting and exposing the origination point with photographs or video clips were required. The primary outcome was the origination of the IPA. Analysis of variance, χ~2 tests and Fisher's tests were used to analyze the differences between groups. The study is registered at Clinicaltrials.gov(No. NCT03071237).Results: Between May 8 and July 31, 2017, 429 patients were assigned for the study, and 419(97.7%) patients had the IPA dissected and recorded through photograph or video and were included in the primary outcome analysis. The median age was 62 years old, and 73.7% were male. Among the patients, 78.5% received laparoscopic surgery. Single IPA origination was identified in 398(95.0%) patients, including gastroduodenal artery(GDA) in154(36.8%) patients, anterior superior pancreaticoduodenal artery(ASPDA) in 130(31.0%) patients, and right gastroepiploic artery(RGEA) in 114(27.2%) patients. Fifteen(3.6%) patients were identified with multiple IPA and 6(1.4%) patients were identified as IPA absence. The differences in the distribution of surgical approach(P=0.003) and geographic area(P=0.030) were statistically significant. No difference was shown in sex, age,gastrectomy type, tumor location, and clinical T, N and M stage.Conclusions: Our study found that the IPA originates from GDA, ASPDA and RGEA in similar proportions.Laparoscopic surgery may be more helpful in dissection of the IPA than open surgery. | Rulin Miao Jianjun Qu Zhengrong Li Daguang Wang Jiang Yu Weidong Zang Yong Li Fenglin Liu Jian Zhang Wu Song Kai Ye Su Yan Wei Wang Shuangyi Ren Lu Zang Changqing Jing Li Zhang Kuan Wang Weihua Fu Lin Fan Bin Liang Gang Zhao Jun Cai Li Yang Jiaming Zhu Jun You Kun Yang Qingxing Huang Zhaojian Niu Ning Ning Xingfeng Qiu Gang Ji Feng Liang Hua Huang Chao Gao Fei Shan Shuangxi Li Yongning Jia Lianhai Zhang Xiangji Ying Yan Zhang Zhaode Bu Xiangqian Su Gang Zhao Ziyu Li Jiafu Ji | 2018 | Chinese Journal of Cancer Research2018，30，5： | 5 |
| 2 | Optical dating of the Jingshuiwan Paleolithic site of Three Gorges, China显示文摘The Jingshuiwan Paleolithic site occu- pies the second terrace on the right bank of the Yangtze River. The lithic assemblage is characterized by choppers and scrapers made on pebbles and large flakes——the typical lithic industry of South China. Deposits of the site are mainly composed of fluvial sediments. Quartz grains extracted from these fluvial sediments from which the artifacts were un- covered were dated using the optically stimulated luminescence/single-aliquot regenerative-dose tech- nique. The dating results show that ancient human activities at this site took place in the early Upper Pleistocene (ca. 70 ka). The successful age analysis of the Jingshuiwan site is considered as a major break- through in chronological analysis of Paleolithic open site in the Three Gorges region and even in South China. The dates obtained help to establish a more complete chronological framework of the Paleolithic cultural sequence in the region, and bear significant implica- tions in studying modern human origins in China. | PEI Shuwen ZHANG Jiafu GAO Xing ZHOU Liping FENG Xingwu CHEN Fuyou | 2006 | Chinese Science Bulletin2006，51，11： | 4 |
| 3 | Germline mutations in hereditary diffuse gastric cancer显示文摘Gastric cancer is one of the leading causes of cancer-related deaths worldwide. Among which, about 1%–3% of gastric cancer patients were characterized by inherited gastric cancer predisposition syndromes, knowing as hereditary diffuse gastric cancer(HDGC). Studies reported that CDH1 germline mutations are the main cause of HDGC. With the help of rapid development of genetic testing technologies and data analysis tools, more and more researchers focus on seeking candidate susceptibility genes for hereditary cancer syndromes. In addition, National Comprehensive Cancer Network(NCCN) guidelines recommend that the patients of HDGC carrying CDH1 mutations should undergo prophylactic gastrectomy or routine endoscopic surveillances. Therefore, genetic counseling plays a key role in helping individuals with pathogenic mutations make appropriate risk management plans. Moreover, experienced and professional genetic counselors as well as a systematic multidisciplinary team(MDT) are also required to facilitate the development of genetic counseling and benefit pathogenic mutation carriers who are in need of regular and standardized risk management solutions. In this review, we provided an overview about the germline mutations of several genes identified in HDGC, suggesting that these genes may potentially act as susceptibility genes for this malignant cancer syndrome. Furthermore, we introduced information for prevention, diagnosis and risk management of HDGC. Investigations on key factors that may have effect on risk management decision-making and genetic data collection of more cancer syndrome family pedigrees are required for the development of HDGC therapeutic strategies. | Hao Zhang Mengmeng Feng Yi Feng Zhaode Bu Ziyu Li Shuqin Jia Jiafu Ji | 2018 | Chinese Journal of Cancer Research2018，30，1： | 4 |
| 4 | Application of fluorescence in situ hybridization in the detection of bladder transitional-cell carcinoma: A multi-center clinical study based on Chinese population显示文摘Objective:To evaluate the diagnostic value of fluorescence in situ hybridization(FISH)in bladder cancer.Methods:We enrolled healthy volunteers and patients who were clinically suspected to have bladder cancer and conducted FISH tests and cytology examinations from August 2007 to December 2008.Receiver operating characteristic(ROC)curve analysis was performed and the area under curve(AUC)values were calculated for both the FISH and urine cytology tests.Results:A cohort of 988 healthy volunteers was enrolled to establish a reference range for the normal population.A total of 4807 patients with hematuria were prospectively,randomly enrolled for the simultaneous analysis of urine cytology,FISH testing,and a final diagnosis as determined by the pathologic findings of a biopsy or a surgically-excised specimen.Overall,the sensitivity of FISH in detecting transitional-cell carcinoma was 82.7%,while that of cytology was 33.4%(p<0.001).The sensitivity values of FISH for non-muscle invasive and muscle invasive bladder transitional-cell carcinoma were 81.7%and 89.6%,respectively(p=0.004).The sensitivity values of FISH for low and high grade bladder cancer were 82.6%and 90.1%,respectively(p=0.002).Conclusion:FISH is significantly more sensitive than voided urine cytology for detecting bladder cancer in patients evaluated for gross hematuria at all cancer grades and stages.Higher sensitivity using FISH was obtained in high grade and muscle invasive tumors. | Liqun Zhou Kaiwei Yang Xuesong Li Yi Ding Dawei Mu Hanzhong Li Yong Yan Jinyi Li Dongwen Wang Wei Li Yulong Cong Jiangping Gao Kewei Ma Yajun Xiao Sheng Zhang Hongyi Jiang Weilie Hu Qiang Wei Xunbo Jin Zhichen Guan Qingyong Liu Danfeng Xu Xin Gao Yongguang Jiang Weimin Gan Guang Sun Qing Wang Yanhui Liu Jianquan Hou Liping Xie Xishuang Song Fengshuo Jin Jiafu Feng Ming Cai Zhaozhao Liang Jie Zhang Dingwei Ye Lin Qi Lulin Ma Jianzhong Shou Yuping Dai Jianyong Shao Ye Tian Shizhe Hong Tao Xu Chuize Kong Zefeng Kang Yuexin Liu Xun Qu Benkang Shi Shaobin Zheng Yi Lin Shujie Xia Dong Wei Jianbo Wu Weiling Fu Zhiping Wang Jianbo Liang | 2019 | Asian Journal of Urology2019，6，1： | 2 |
| 5 | Rapid and effective treatment of traumatic spinal cord injury using stem cell derived exosomes显示文摘Traumatic spinal cord injury is a fatal acute event without effective clinical therapies.Following the trauma,immediate neural protection and microenvironment mitigation are vitally important for nerve tissue repair,where stem cell-based therapies could be eclipsed by the deficiency of cells due to the hostile microenvironment as well as the transport and preservation processes.Effective emergency strategies are required to be convenient,biocompatible,and stable.Herein,we assess an emergency cell-free treatment using mesenchymal stem cell-derived exosomes,which have proven capable of comprehensive mitigation of the inhibitory lesion microenvironment.The clinically validated fibrin glue is utilized to encapsulate the exosomes and in-situ gelates in transected rat spinal cords to provide a substrate for exosome delivery as well as nerve tissue growth.The emergency treatment alleviates the inflammatory and oxidative microenvironment,inducing effective nerve tissue repair and functional recovery.The therapy presents a promising strategy for effective emergency treatment of central nervous system trauma。 | Jiafu Mu Jiahe Wu Jian Cao Teng Ma Liming Li Shiqing Feng Jianqing Gao | 2021 | Asian Journal of Pharmaceutical Sciences2021，16，6： | 1 |
| 6 | Clinicopathological and Immunohistochemical Characterisation of Gastric Schwannomas in 29 Cases显示文摘 | Lijun Zheng Xiaojiang Wu Martin E. Kreis Zhen Yu Lijin Feng Chunqiu Chen Bin Xu Zhaode Bu Ziyu Li Jiafu Ji Paul Enck | 2014 | Gastroenterology Research and Practice2014，，： | 1 |
| 7 | Solving the rotating seru production problem with dynamic multi-objective evolutionary algorithms显示文摘Today's volatile market conditions in electronic industries have lead to a new production system,seru(which is the Japanese pronunciation for cell),and has been widely implemented in hundreds of Japanese and other Asia companies.In particular,the rotating seru has been widely implemented,where workers are fully cross-trained with the same skill level but may be different on the proficiency of performing tasks.The rotating seru production problem,which determines the rotating sequence of workers as well as the assembling sequence of jobs,is difficult to solve due to conflicting objectives and dynamic release of customer demands.To solve this problem,we propose a dynamic multiobjective NSGA-II based memetic algorithm.Moreover,to preserve desirable population diversity and improve the searching efficiency,we propose different problem-specific evolutionary strategies.Finally,we test the performance of our proposed memetic algorithm with other state-of-the-art multi-objective evolutionary algorithms and demonstrate the effectiveness of our proposed algorithm. | Feng Liu Kan Fang Jiafu Tang Yong Yin | 2022 | Journal of Management Science and Engineering2022，7，1： | 1 |
| 8 | MAGI1 inhibits migration and invasion via blocking MAPK/ERK signaling pathway in gastric cancer显示文摘Objective: To explore the association of membrane-associated guanylate kinase inverted 1(MAGI1) with gastric cancer(GC) and the related molecular mechanisms.Methods: The reverse transcription-polymerase chain reaction(RT-PCR) and immunohistochemistry(IHC)were utilized to measure the MAGI1 expression level in GC tissues. Quantitative real-time PCR and Western blotting were used to ensure the MAGI1 expression in GC cell lines. Small hairpin RNA(sh RNA) was applied for knockdown of endogenous MAGI1 in GC cells. MTT assay and colony formation assay, scratch wounding migration assay and transwell chamber migration assay, as well as transwell chamber invasion assay were employed respectively to investigate the GC cell proliferation, migration and invasion in MAGI1-knockdown and control GC cells. The potential molecular mechanism mediated by MAGI1 was studied using Western blotting and RT- PCR.Results: RT-PCR and IHC verified MAGI1 was frequently expressed in matched adjacent noncancerous mucosa compared with GC tissues and the expression of MAGI1 was related to clinical pathological parameters. Functional assays indicated that MAGI1 knockdown significantly promoted GC cell migration and invasion. Further mechanism investigation demonstrated that one pathway of MAGI1 inhibiting migration and invasion was mainly by altering the expression of matrix metalloproteinases(MMPs) and epithelial-mesenchymal transition(EMT)-related molecules via inhibiting MAPK/ERK signaling pathway.Conclusions: MAGI1 was associated with GC clinical pathological parameters and acted as a tumor suppressor via inhibiting of MAPK/ERK signaling pathway in GC. | Shuqin Jia Jiajia Lu Tingting Qu Yi Feng Xiaohong Wang Caixia Liu Jiafu Ji | 2017 | Chinese Journal of Cancer Research2017，29，1： | 1 |
| 9 | Spin-selective corner reflector for retro-reflection and absorption by a circular dichroitic manner显示文摘Recently, we have witnessed an extraordinary spurt in attention toward manipulating electromagnetic waves by metasurfaces. Particularly, tailoring of circular polarization has attracted great amounts of interest in both microwave and optics regimes. Circular dichroism, an exotic chiroptical effect of natural molecules, has aroused discussion about this issue, yet it is still in its infancy. Herein, we initiate circular dichroism followed by controlling spin-selective wavefronts via chiral metasurfaces. An N-shaped chiral resonator loaded with two lumped resistors is proposed as the meta-atom producing an adequate phase gradient. Assisted by the ohmic dissipation of the introduced resistors, the effect of differential absorption provides an auxiliary degree of freedom for developing circularly polarized waves with a designated spin state. A planar corner reflector that can achieve retro-reflection and absorption for right-and left-handed circularly polarized incidence is theoretically simulated and experimentally observed at microwave frequency. Thus, our effort provides an alternative approach to tailoring electromagnetic waves in a circular dichroitic manner and may also find applications in multi-functional systems in optics and microwave regimes. | HE WANG YAO JING YONGFENG LI LINGLING HUANG MAOCHANG FENG QI YUAN JIAFU WANG JIEQIU ZHANG SHAOBO QU | 2021 | Photonics Research2021，9，5： | 1 |
| 10 | Direct field-to-pattern monolithic design of holographic metasurface via residual encoderdecoder convolutional neural network显示文摘Complex-amplitude holographic metasurfaces(CAHMs)with the flexibility in modulating phase and amplitude profiles have been used to manipulate the propagation of wavefront with an unprecedented level,leading to higher image-reconstruction quality compared with their natural counterparts.However,prevailing design methods of CAHMs are based on Huygens-Fresnel theory,meta-atom optimization,numerical simulation and experimental verification,which results in a consumption of computing resources.Here,we applied residual encoder-decoder convolutional neural network to directly map the electric field distributions and input images for monolithic metasurface design.A pretrained network is firstly trained by the electric field distributions calculated by diffraction theory,which is subsequently migrated as transfer learning framework to map the simulated electric field distributions and input images.The training results show that the normalized mean pixel error is about 3%on dataset.As verification,the metasurface prototypes are fabricated,simulated and measured.The reconstructed electric field of reverse-engineered metasurface exhibits high similarity to the target electric field,which demonstrates the effectiveness of our design.Encouragingly,this work provides a monolithic field-to-pattern design method for CAHMs,which paves a new route for the direct reconstruction of metasurfaces. | Ruichao Zhu Jiafu Wang Tianshuo Qiu Dingkang Yang Bo Feng Zuntian Chu Tonghao Liu Yajuan Han Hongya Chen Shaobo Qu | 2023 | Opto-Electronic Advances2023，6，8： | 0 |
| 11 | Reducing the global cancer burden with gastrointestinal screening: China's 30 years practice显示文摘Gastrointestinal(GI) cancers include esophageal [EC(International Classification of Disease 10~(th) revision: C15)], gastric [GC(C16)], and colorectal [CRC(C18-C21)] cancers. China is a high-incidence country of GI cancers. | Lei Yang Li Feng Yong Zhu Ning Wang Xinpu Lu Fanghui Gu Xiaotian Zhang Jiafu Ji | 2024 | Cancer Biology & Medicine2024，21，3： | 0 |
| 12 | Quadruple-band metamaterial absorber based on the cuboid dielectric particles显示文摘In this work,a quadruple-band dielectric metamaterial absorber(MMA)was proposed and studied,which is composed of eight cuboid dielectric particles and a metallic ground plate.When electromagnetic wave is incident on the dielectric particles,dielectric particles act as resonators and produce abundant resonant modes,which can result in perfect absorption.In simulation,four absorption peaks are observed at 9.13,9.62,10.0 and 10.46 GHz with 88%,89%,100%and 96%,respectively.By adjusting geometry parameters of the dielectric particles,dielectric MMAs with different bands can be obtained.Further investigation shows that the absorption peaks can be changed by increasing the permittivity of the dielectric.Based on the designing technique of using simple cuboid dielectric particles directly acting as resonator,this work provides a simple method to construct multiband alldielectric MMA. | Wenjie Wang Mingde Feng Jun Wang Zhiqiang Li Jiafu Wang Hua Ma Shaobo Qu | 2018 | Journal of Advanced Dielectrics2018，8，4： | 0 |
| 13 | Cluster Effects during High Pressure Supersonic Molecular Beam Injection into Plasma | YAO Lianghua FENG Beibin DONG Jiafu LI Wenzhong FENG Zhen HONG Wenyu LI Bo | 2002 | 中国核科技报告2002，，1： | 0 |
| 14 | Research on the Penetration Characteristic of Supersonic Molecule Beam on the HL-1M Tokamak | DONG Jiafu LUO Junling TANG Nianyi LI Wei ZHONG Yunze LIU Yi FU Binzhong YAO Lianghua FENG Baibing QIN Yunwen | 2002 | 中国核科技报告2002，，1： | 0 |
| 15 | Simultaneous photoelectrochemical detection of dual microRNAs by capturing CdS quantum dots and methylene blue based on target-initiated strand displaced amplification显示文摘Herein,we propose a novel photoelectrochemical(PEC) biosensor for dual microRNAs(miRNAs) highly sensitive and simultaneous biosensing based on strand displaced amplification(SDA) reaction.The recognition of HmiR-21 and Hlet-7 a by microRNA-21 and let-7 a leads to their change in hairpin structures,subsequently initiating the immobilization of abundant CdS quantum dots(CdS QD s) and methylene blue(MB) based on SDA reaction.The immobilized CdS QDs and MB produce both high PEC currents under430 nm light and 627 nm light illumination,respectively,and the generated PEC currents are closely relied on target miRNAs amounts.Thus,highly sensitive and simultaneous detection of microRNA-21 and let-7 a was readily achieved with detection limit at 6.6 fmol/L and 15.4 fmol/L based on 3σ,respectively.Further,this PEC biosensor was applied in simultaneous analysis of miRNA-21 and let-7 a in breast cancer patient’s serum with acceptable results.We expect this biosensor will find more useful application in diagnosis of miRNA-related diseases. | Jiafu Chang Wenxin Lv Jiahui Wu Haiyin Li Feng Li | 2021 | Chinese Chemical Letters2021，32，2： | 0 |
| 16 | All-dielectric metamaterial frequency selective surface based on spatialarrangement ceramic resonators显示文摘In this paper,we demonstrate a method of designing all-dielectric metamaterial frequency selective surface(FSS)with ceramic resonators in spatial arrangement.Compared with the traditional way,spatial arrangement provides a flexible way to handle the permutation and combination of different ceramic resonators.With this method,the resonance response can be adjusted easily to achieve pass/stop band effects.As an example,a stop band spatial arrangement all-dielectric metamaterial FSS is designed.Its working band is in 11.65–12.23 GHz.By adjusting permittivity and geometrical parameters of ceramic resonators,we can easily modulate the resonances,band pass or band stop characteristic,as well as the working band. | Liyang Li Jun Wang Mingde Feng Hua Ma Jiafu Wang Hongliang Du Shaobo Qu | 2017 | Journal of Advanced Dielectrics2017，7，2： | 0 |
| 17 | All-dielectric metamaterial frequency selective surface显示文摘Frequency selective surface(FSS)has been extensively studied due to its potential applications in radomes,antenna reflectors,high-impedance surfaces and absorbers.Recently,a new principle of designing FSS has been proposed and mainly studied in two levels.In the level of materials,dielectric materials instead of metallic patterns are capable of achieving more functional performance in FSS design.Moreover,FSSs made of dielectric materials can be used in different extreme environments,depending on their electrical,thermal or mechanical properties.In the level of design principle,the theory of metamaterial can be used to design FSS in a convenient and concise way.In this review paper,we provide a brief summary about the recent progress in all-dielectric metamaterial frequency selective surface(ADM-FSS).The basic principle of designing ADM-FSS is summarized.As significant tools,Mie theory and dielectric resonator(DR)theory are given which illustrate clearly how they are used in the FSS design.Then,several design cases including dielectric particle-based ADM-FSS and dielectric network-based ADM-FSS are introduced and reviewed.After a discussion of these two types of ADM-FSSs,we reviewed the existing fabrication techniques that are used in building the experiment samples.Finally,issues and challenges regarding the rapid fabrication techniques and further development aspects are discussed. | Jun Wang Shaobo Qu Liyang Li Jiafu Wang Mingde Feng Hua Ma Hongliang Du Zhuo Xu | 2017 | Journal of Advanced Dielectrics2017，7，5： | 0 |
| 18 | Characteristics of lymph node stations/basins metastasis and construction and validation of a preoperative combination prediction model that accurately excludes lymph node metastasis in early gastric cancer显示文摘Objective:To explore the candidate indications for function-preserving curative gastrectomy and sentinel lymph node navigation surgery in early gastric cancer(EGC).Methods:The clinicopathological data of 561 patients with EGC who underwent radical gastrectomy for gastric cancer at Peking University Cancer Hospital from November 2010 to November 2020 with postoperative pathological stage pT1 and complete examination data,were collected.Pearson’s Chi-square test was used and binary logistic regression was employed for univariate and multivariate analyses.Combined analysis of multiple risk and protective factors for lymph node metastasis(LNM)of EGC was performed.A negative predictive value(NPV)combination model was built and validated.Results:LNM occurred in 85 of 561 patients with EGC,and the LNM rate was 15.15%.NPV for LNM reached 100%based on three characteristics,including ulcer-free,moderately well differentiation and patient<65years old or tumor located at the proximal 1/3 of the stomach.Regarding lymphatic basin metastasis,multivariate analysis showed that the metastatic proportion of the left gastric artery lymphatic basin was significantly higher in male patients compared with female patients(65.96%vs.38.89%,P<0.05).The proportion of right gastroepiploic artery lymphatic basin metastasis in patients with a maximum tumor diameter>2 cm was significantly greater than that noted in patients with a maximum tumor diameter≤2 cm(60.78%vs.28.13%,P<0.05).Conclusions:Characteristics of lymph node stations/basins metastasis will facilitate precise lymph node resection.The NPV for LNM reaches 100%based on the following two conditions:young and middle-aged EGC patients,well-differentiated tumors,and without ulcers;or well-differentiated tumors,without ulcers,and tumors located in the proximal stomach.These findings can be used as the recommended indications for functionpreserving curative gastrectomy and sentinel lymph node navigation surgery. | Mengyu Feng Jingtao Wei Ke Ji Yinan Zhang Heli Yang Xiaojiang Wu Ji Zhang Zhaode Bu Jiafu Ji | 2022 | Chinese Journal of Cancer Research2022，34，5： | 0 |
| 19 | Macrophage-derived exosomal miR-342-3p promotes the progression of renal cell carcinoma through the NEDD4L/CEP55 axis显示文摘Due to its difficulty in early diagnosis and lack of sensitivity to chemotherapy and radiotherapy,renal cell carcinoma(RCC)remains to be a frequent cause of cancer-related death.Here,we probed into new targets for its early diagnosis and treatment for RCC.microRNA(miRNA)data of M2-EVs and RCC were searched on the Gene Expression Omnibus database,followed by the prediction of the potential downstream target.Expression of target genes was measured via RT-qPCR and Western blot,respectively.M2 macrophage was obtained viaflow cytometry with M2-EVs extracted.The binding ability of miR-342-3p to NEDD4L and to CEP55 ubiquitination was studied with their roles in the physical abilities of RCC cells assayed.Subcutaneous tumor-bearing mouse models and lung metastasis models were prepared to observe in vivo role of target genes.M2-EVs induced RCC growth and metastasis.miR-342-3p showed high expression in both M2-EVs and RCC cells.M2-EVs carrying miR-342-3p promoted RCC cell abilities to proliferate,invade and migrate.In RCC cells,M2-EV-derived miR-342-3p could specifically bind to NEDD4L and consequently elevate CEP55 protein expression via suppressing NEDD4L,thereby exerting tumor-promoting effects.CEP55 could be degraded by ubiquitination under the function of NEDD4L,and miR-342-3p delivered by M2-EVs facilitated the RCC occurrence and development by activating the PI3K/AKT/mTOR signaling pathway.In conclusion,M2-EVs promote RCC growth and metastasis by delivering miR-342-3p to suppress NEDD4L and subsequently inhibit CEP55 ubiquitination and degradation via activation of the PI3K/AKT/mTOR signaling pathway,strongly driving the proliferative,migratory and invasive of RCC cells. | JIAFU FENG BEI XU CHUNMEI DAI YAODONG WANG GANG XIE WENYU YANG BIN ZHANG XIAOHAN LI JUN WANG | 2021 | Oncology Research2021，29，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员