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39篇 您的检索式:作者名="JIANLIANG ZHOU"
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1Failure behavior of a rock-coal-rock combined body with a weak coal interlayer显示文摘Using an MTS 815 testing machine,the deformation and failure behavior of a rock-coal-rock combined body containing a weak coal interlayer has been investigated and described in this paper.Uniaxial loading leads to the appearance of mixed cracks in the coal body which induce instability and lead to bursts in coal.If the mixed crack propagates at a sufficiently high speed to carry enough energy to damage the roof rock,then coal and rock bursts may occur-this is the main mechanism whereby coal bumps or coal and rock bursts occur after excavation unloading.With increasing confining pressure,the failure strength of a rock-coal-rock combined body gradually increases,and the failure mechanism of the coal interlayer also changes,from mixed crack damage under low confining pressures,to parallel crack damage under medium confining pressures,and finally to single shear crack damage or integral mixed section damage under high confining pressures.In general,it is shown that a weak coal interlayer changes the form of overall coal damage in a rock-coal-rock combined body and reduces the overall stability of a coal body.Therefore,the whole failure behavior of a rock-coal-rock combined body in large cutting height working faces is controlled by these mechanisms.Zuo Jianping Wang Zhaofeng Zhou Hongwei Pei Jianliang Liu Jianfeng 2013International Journal of Mining Science and Technology2013,23,6:32
2Clinical features and outcomes of diffuse large B-cell lymphoma based on nodal or extranodal primary sites of origin:Analysis of 1,085 WHO classified cases in a single institution in China显示文摘Objective: To explore the clinicobiologic features and outcomes of diffuse large B-cell lymphoma(DLBCL)patients in China according to the primary site.Methods: A total of 1,085 patients diagnosed with DLBCL in National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College during a 6-year period were enrolled. Their clinical characteristics and outcomes were analyzed according to the primary site.Results: In the 1,085 patients, 679(62.6%) cases were nodal DLBCL(N-DLBCL) and 406 cases(37.4%) were extranodal DLBCL(EN-DLBCL). The most common sites of N-DLBCL were lymphonodus(64.8%), Waldeyer's ring(19.7%), mediastinum(12.8%) and spleen(2.7%), while in EN-DLBCL, stomach(22.4%), intestine(16.0%),nose and sinuses(8.9%), testis(8.4%), skin(7.9%), thyroid(6.9%), central nervous system(CNS)(6.4%), breast(5.7%), bone(3.4%), and salivary gland(2.7%) were most common. N-DLBCL patients tend to present B symptoms, bulky disease, and elevated LDH more often, while age >60 years, extranodal sites >1, Ann Arbor stage I or II, bone marrow involvement, and Ki-67 index >90% were usually seen in EN-DLBCL. The 5-year overall survival(OS) rate and progression-free survival(PFS) rate for all patients were 62.5% and 54.2%. The 5-year OS rate for patients with N-DLBCL and EN-DLBCL were 65.5% and 56.9%(P=0.008), and the 5-year PFS were57.0% and 49.0%(P=0.020). Waldeyer's ring originated DLBCL possessed the highest 5-year OS rate(83.6%) and PFS rate(76.9%) in N-DLBCL. The top five EN-DLBCL subtypes with favorable prognosis were stomach,breast, nose and sinuses, lung, salivary gland, with 5-year OS rate: 70.3%, 69.6%, 69.4%, 66.7% and 63.6%,respectively. While CNS, testis, oral cavity and kidney originated EN-DLBCL faced miserable prognosis, with 5-year OS rate of 26.9%, 38.2%, and 42.9%.Conclusions: In our study, primary sites were associated with clinical characteristics and outcomes. Compared with EN-DLBCL, N-DLBCL had better prognosis.Yuankai Shi Ying Han Jianliang Yang Peng Liu Xiaohui He Changgong Zhang Shengyu Zhou Liqiang Zhou Yan Qin Yongwen Song Yueping Liu Shulian Wang Jing Jin Lin Gui Yan Sun 2019Chinese Journal of Cancer Research2019,31,1:19
3High precision landing site mapping and rover localization for Chang'e-3 mission显示文摘This paper presents the comprehensive results of landing site topographic mapping and rover localization in Chang’e-3 mission.High-precision topographic products of the landing site with extremely high resolutions(up to 0.05 m)were generated from descent images and registered to CE-2 DOM.Local DEM and DOM with 0.02 m resolution were produced routinely at each waypoint along the rover traverse.The lander location was determined to be(19.51256°W,44.11884°N,-2615.451 m)using a method of DOM matching.In order to reduce error accumulation caused by wheel slippage and IMU drift in dead reckoning,cross-site visual localization and DOM matching localization methods were developed to localize the rover at waypoints;the overall traveled distance from the lander is 114.8 m from cross-site visual localization and 111.2 m from DOM matching localization.The latter is of highest accuracy and has been verified using a LRO NAC image where the rover trajeactory is directly identifiable.During CE-3 mission operations,landing site mapping and rover localization products including DEMs and DOMs,traverse maps,vertical traverse profiles were generated timely to support teleoperation tasks such as obstacle avoidance and rover path planning.LIU ZhaoQin DI KaiChang PENG Man WAN WenHui LIU Bin LI LiChun YU TianYi WANG BaoFeng ZHOU JianLiang CHEN HongMin 2015Science China(Physics,Mechanics & Astronomy)2015,58,1:15
4Pre-LOI trajectory maneuvers of the CHANG'E-2 libration point mission显示文摘This paper addresses pre-LOI (before Lissajous orbit insertion) trajectory maneuvers for the libration point mission of CHANG'E-2,which is the first Chinese satellite to fly to the Sun-Earth L2 libration point and the first satellite ever to fly to the L2 point from lunar orbit.First,a transfer trajectory for the mission is designed based on InterPlanetary Superhighway theory under the constraint of the remaining propellant,TT&C (telemetry,track and command) and sunlight conditions.The effects of trajectory maneuver errors on the mission are also analyzed.Second,based on the analysis results,the article investigates the trajectory maneuver schemes for the lunar escape and transfer trajectory maneuvers employing mathematical models and operational strategies.The mission status based on our maneuver schemes is then presented,and the results of control operation and corresponding analysis are provided in detail.Finally,the future trajectory maneuver in the Lissajous orbit is discussed.According to the analysis of the CHANG'E-2 TT&C data,the trajectory maneuver schemes proposed in the article work properly and efficiently.WU WeiRen LIU Yong LIU Lei ZHOU JianLiang TANG GeShi CHEN YongZhi 2012Science China(Information Sciences)2012,55,6:12
5Autologous hematopoietic stem cell transplantation in chemotherapy-sensitive lymphoblastic lymphoma: treatment outcome and prognostic factor analysis显示文摘Objective: The study evaluated the effectiveness of autologous hematopoietic stem cell transplantation(AHSCT) in the treatment of lymphoblastic lymphoma(LL).Methods: We retrospectively analyzed the data from 41 patients with chemotherapy-sensitive LL who underwent hematopoietic stem cell transplantation(HSCT) from December 1989 to December 2009 in a single institution.Results: HSCT was conducted as first-line consolidation therapy and salvage therapy in 36 and 5 patients, respectively. The median follow-up was 97.1 months(range, 24.6-173.1 months). The 5-year overall survival(OS) and event-free survival(EFS) rate were 64% and 47% for the initially treated patients, respectively, and were both 20% for the relapsed ones. Bone marrow(BM) involvement and chemotherapy cycles prior to transplantation were identified as significant prognostic factors for EFS in multivariate analysis.Conclusions: These results confirm that AHSCT is a reasonable option for chemotherapy-sensitive LL patients in first complete remission(CR1).Youwu Shi Shengyu Zhou Xiaohui He Xiaohong Han Shikai Wu Feng Pan Peng Liu Yinyu Liu Yingheng Lei Hongzhi Zhang Jianliang Yang Yan Qin Changgong Zhang Sheng Yang Liya Zhao Kehuan Luo Guanqing Wu Yan Sun Yuankai Shi 2015Chinese Journal of Cancer Research2015,27,1:9
6Carbon dioxide adsorption of two-dimensional carbide MXenes显示文摘Two-dimensional carbide MXenes(Ti_3C_2T_x and V_2CT_x)were prepared by exfoliating MAX phases(Ti_3AlC_2 and V_2AlC)powders in the solution of sodium fluoride(NaF)and hydrochloric acid(HCl).The specific surface area(SSA)of as-prepared Ti_3C_2T_x was 21 m^2/g,and that of V_2CT_x was 9 m^2/g.After intercalation with dimethylsulfoxide,the SSA of Ti_3C_2T_x was increased to 66 m^2/g;that of V_2CT_x was increased to 19 m^2/g.Their adsorption properties on carbon dioxide(CO_2)were investigated under 0–4 MPa at room temperature(298 K).Intercalated Ti_3C_2T_x had the adsorption capacity of 5.79 mmol/g,which is close to the capacity of many common sorbents.The theoretical capacity of Ti_3C_2T_x with the SSA of 496 m^2/g was up to 44.2 mmol/g.Additionally,due to high pack density,MXenes had very high volume-uptake capacity.The capacity of intercalated Ti_3C_2T_(x )measured in this paper was 502 V·v^(–1).This value is already higher than volume capacity of most known sorbents.These results suggest that MXenes have some advantage features to be researched as novel CO_2 capture materials.Bingxin WANG Aiguo ZHOU Fanfan LIU Jianliang CAO Libo WANG Qianku HU 2018Journal of Advanced Ceramics2018,7,3:9
7Lipopolysaccharide promotes angiogenesis in mice model of HCC by stimulating hepatic stellate cell activation via TLR4 pathway显示文摘Angiogenesis 在 hepatocellular 癌(HCC ) 的前进起一个关键作用。这研究试图调查 lipopolysaccharide (LPS ) 是否能在这个过程支持 HCC angiogenesis 和肝的星形的房间(HSC ) 的角色。在 vivo orthotopic HCC,模型和在 vitro 的 HSC 上的 LPS 的效果被学习。我们的结果在老鼠在 HCC 生长和 angiogenesis 的提升期间表明了那导致 LPS 的 HSC 激活。LPS-TLR4 (像使用费的受体 4 ) 在 HSC 的小径为 HCC angiogenesis 负责。从 HSC 的 pro-angiogenic 因素的导致 LPS 的分泌物能支持 endothelial 房间移植和 tubulogenesis。这研究建议 LPS 在肿瘤基质与 HSC 行动并且支持在 HCC 增加 angiogenesis 的 pro-angiogenic 因素的分泌物(吗?作者 2017。代表生物化学和房间生物学的研究所由牛津大学出版社出版了,为生物科学的上海研究所,中国科学院。版权所有。为权限,请发邮件:journals.permissions@oup.com。)Yi Lu Jianliang Xu Shuxian Chen Zheng Zhou Nan Lin 2017Acta Biochimica et Biophysica Sinica2017,49,11:6
8Clinical features, survival and prognostic factors of primary testicular diffuse large B-cell lymphoma显示文摘Objective: To assess the clinical features, survival and prognostic factors of primary testicular diffuse large B-cell lymphoma(DLBCL).Methods: A retrospective study of 37 patients with primary testicular DLBCL was carried out from November 2003 to May 2012. Their clinical features, survival and prognostic factors were analyzed.Results: During a median follow-up period of 39.8 months(5.4-93.0 months), the median progression-free survival(PFS) was 26.2 months(95% CI: 0-65 months) and the 3-year overall survival(OS) rate was 78.4%. Within the whole cohort, the factors significantly associated with a superior PFS were limited stage(stage I/II), lactate dehydrogenase(LDH) ≤245 U/L, international prognostic index(IPI) ≤1, primary tumor diameter <7.5 cm, and patients who had complete response(CR) and received doxorubicin-contained chemotherapy(P<0.05). There was a trend toward superior outcome for patients who received combined therapy(surgery/chemotherapy/radiotherapy)(P=0.055). Patients who had CR, primary tumor diameter <7.5 cm and IPI score ≤1 were significantly associated with longer PFS at multivariate analysis.Conclusions: Primary testicular DLBCL had poorer survival. CR, primary tumor diameter and IPI were independent prognostic factors. The combined therapy of orchectomy, doxorubicin-contained chemotherapy and contralateral testicular radiotherapy(RT) seemed to improve survival.Bo Jia Yuankai Shi Mei Dong Fengyi Feng Sheng Yang Hua Lin Liqiang Zhou Shengyu Zhou Shanshan Chen Jianliang Yang Peng Liu Yan Qin Changgong Zhang Lin Gui Lin Wang Xue Wang Xiaohui He 2014Chinese Journal of Cancer Research2014,26,4:5
9Chang’E-2 satellite asymmetric-descent orbit control technology显示文摘To accomplish high-resolution imaging of the preselected landing area,it was necessary for the Chang’E-2 mission to perform orbital maneuvering on the far side of the moon to meet the conditional height requirement of the imaging area.Engine shut-down would be executed invisibly on the back side of the moon if the descent maneuver mode opposite to the target perilune or the fuel optimal maneuver mode was used.To ensure the satellite safety,the project collectivety required that the engine shutdown should be designed to be executed in the domestic segmental arcs and meet the requirement of satellite emergency treatment simultaneously.Accordingly,the asymmetric-descent orbit control technology was adopted by offsetting the ma-neuver point,which obtained the orbit control parameters of finite-thrust mode with an iteration algorithm and modified the results with target perilune drift estimation.The Chang’E-2 satellite declined to the target of 100 km×15 km orbit successfully on 26 October 2010,and has been flying for 32 circles in the experimental orbit to accomplish the preselected landing area imaging.This paper describes the mechanism and realization method of the asymmetric-descent orbit control technology and evaluates the maneuver effect with the actual mission data.ZHOU JianLiang LIU Yong PENG DeYun ZHAO FengCai 2011Science China(Technological Sciences)2011,54,9:4
10Autologous peripheral blood stem cell mobilization following dose-adjusted cyclophosphamide, doxorubicin, vincristine and prednisolone chemotherapy alone or in combination with rituximab in treating high-risk non-Hodgkin's lymphoma显示文摘Background: The regimen of cyclophosphamide, doxorubicin, vincristine, and prednisolone(CHOP) is an eicient treatment of non-Hodgkin's lymphoma(NHL). This study aimed to assess the eicacy and toxicity of dose-adjusted CHOP alone or in combination with rituximab(R-CHOP) by examining the stem cell mobilization in NHL patients. Factors afecting the collection of CD34+ cells were also explored.Methods: Our retrospective study included 39 patients eligible for autologous stem cell transplantation: 14 patients who expressed CD20 and were inancially eligible received R-CHOP for autologous peripheral blood stem cell(APBSC) mobilization; the remaining 25 patients received CHOP.Results: The median CD34+ cell yield was 7.01 × 106 cells/kg body weight(range 1.49–28.39 × 106 cells/kg body weight), with only two patients failing to meet the target CD34+ cell harvest of ber of apheresis procedures per patient was 1(range 1–3). The≥2.0 APBS× 106 cells/kg body weight. The median numC mobilization yield of the CHOP group appeared to be higher than that of the R-CHOP group(P response(CR) rate in = 0.005), whereas the success rate was similar between groups. R-CHOP elevated the completeB cell lymphoma patients as compared with CHOP(P = 0.01). No signiicant diferences in toxicity or engraftment were observed between the two groups.Conclusion: The present study demonstrated that dose-adjusted CHOP chemotherapy efectively mobilized APBSCs in NHL patients and that the addition of rituximab to dose-adjusted CHOP chemotherapy elevated the CR rate for patients with B-cell lymphoma.Yuankai Shi Ping Zhou Xiaohong Han Xiaohui He Shengyu Zhou Peng Liu Jianliang Yang Changgong Zhang Lin Gui Yan Qin Sheng Yang Liya Zhao Jiarui Yao Shuxiang Zhang 2015Chinese Journal of Cancer2015,34,11:4
11Synthesis, Crystal Structure and DNA Cleavage Activity of a Ternary Copper(ll) Complex of Dipyrido[3,2-d:2',3'-f]-quinoxa- line and Glycine显示文摘Zhang, Shouchun Chun, Xiaogai Chen, Yun Zhou, Jianliang 2011Chinese Journal of Chemistry2011,29,1:2
12Addition of rituximab is not associated with survival benefit compared with CHOP alone for patients with stage I diffuse large B-cell lymphoma显示文摘Background:The role of rituximab in combination with CHOP regimen in patients with stage I diffuse large B-cell lymphoma(DLBCL) remains to be defined.We aimed to compare CHOP plus rituximab(R-CHOP) with CHOP alone and determine the value of radiotherapy in these patients.Methods:Between 2003 and 2009,140 untreated patients with stage I DLBCL were retrospectively analyzed in this study.Results:Seventy-eight patients were treated in R-CHOP group and 62 in CHOP group.Ninety-one patients received additional radiotherapy at the end of chemotherapy.The different treatment groups were well-balanced with respect to baseline characteristics.Complete response(CR) rate was 77% both in R-CHOP and CHOP groups(P=0.945).After a median follow-up period of 56 months,patients received R-CHOP regimen had similar 5-year progression-free survival(PFS)(76%vs.85%;log-rank P=0.215)and 5-year overall survival(OS)(90%vs.96%;log-rank P=0.175) compared with those with CHOP alone.Patients with radiotherapy had significantly increased 5-year PFS compared with those who had chemotherapy alone(86%vs.71%;log-rank P=0.005).At multivariate analysis,patients who had CR(P=0.008) and received radiotherapy(P=0.003) were significantly associated with superior PFS.Conclusions:CHOP alone could be as effective as R-CHOP regimen and additional radiotherapy would be necessary for stage I or stage I non-bulky DLBCL patients.Bo Jia Yuankai Shi Suyi Kang Sheng Yang Shaoxuan Hu Yexiong Li Mei Dong Weihu Wang Jianliang Yang Liqiang Zhou Peng Liu Shengyu Zhou Yan Qin Lin Gui Changgong Zhang Hua Lin Shanshan Chen Lin Wang Xiaohui He 2015Chinese Journal of Cancer Research2015,27,5:2
13Improving the mid-infrared energy absorption efficiency by using a dual-band metamaterial absorber显示文摘In this paper, a dual-band mid-infrared metamaterial absorber was proposed to improve the energy absorption efficiency. Up to 99% absorption was obtained at 9.03 and 11.83 μm in the simulation, and each absorption band can be tuned by the dielectric spacing layer, i.e., the dielectric constant and its thickness. The dual-band absorption mechanism was analyzed, and the quite well absorption performance at large incident angles was also presented. The results of this study can be applied in the field of thermal absorbing and solar energy harvesting.Nan Zhang Peiheng Zhou Shifeng Zou Xiaolong Weng Jianliang Xie Longjiang Deng 2014Progress in Natural Science:Materials International2014,24,2:2
14Prognostic value of BCL2 and TP53 genetic alterations for diffuse large B-cell lymphoma patients treated with R-CHOP显示文摘Objective:Limited data about the prognostic significance of BCL2 mutations and BCL2 copy number variations in diffuse large B-cell lymphoma(DLBCL)are available.This study aimed to comprehensively describe BCL2 genetic alterations in DLBCL patients,and examine correlation of BCL2,TP53 and other genetic alterations with outcomes in patients treated with R-CHOP.Methods:Probe capture-based high-resolution sequencing was performed on 191 patients diagnosed with de novo DLBCL.MYC,BCL2,and BCL6 protein expressions were detected by immunohistochemistry.Results:The presence of BCL2 alterations significantly correlated with poor progression-free survival(PFS)(5-year PFS:13.7%vs.40.8%;P=0.003)and overall survival(OS)(5-year OS:34.0%vs.70.9%;P=0.036).Importantly,patients who harbored BCL2 gain/amplifications(BCL2GA/AMP)also had a remarkably inferior 5-year PFS(11.1%vs.38.3%;P<0.001)and OS(22.1%vs.69.6%;P=0.009).In contrast,neither BCL2 mutations nor BCL2 translocations were significantly prognostic for survival.Multivariable analyses showed that the presence of BCL2 alterations,especially BCL2GA/AMP,TP53 mutations,and International Prognostic Index(IPI)were significantly associated with inferior PFS and OS.Novel prognostic models for OS were constructed based on 3 risk factors,including BCL2 alterations(Model 1)or BCL2GA/AMP(Model 2),TP53 mutations,and IPI,to stratify patients into 4 risk groups with different survival outcomes.Conclusions:This study showed that DLBCL patients treated with R-CHOP,BCL2 alterations,especially BCL2GA/AMP and TP53 mutations were significantly associated with inferior outcomes,which were independent of the IPI.The novel prognostic models we proposed predicted outcomes for DLBCL patients treated with R-CHOP,but further validation of the prognostic models is still warranted.Yan Qin Haizhu Chen Peng Liu Changgong Zhang Jianliang Yang Lin Gui Xiaohui He Liqiang Zhou Shengyu Zhou Shiyu Jiang Hongxin Jiang Yuankai Shi 2022Cancer Biology & Medicine2022,19,6:2
15Effect of Sedimentation on the Microwave Permeability of FeSiAl Composites显示文摘In order to achieve an easy fabrication and considerable directional orientation, we use a sedimentation method to prepare composites consisting of Fe Si Al flakes. The flakes are dispersed in hydroxylated acrylic resin solution in sonication and natural form into laminated composite samples. Then, the toroidal rings are made with the prepared laminated composite samples. Compared with random orientational Fe Si Al flakes in the composite, the complex permeability of laminated sample has been obviously improved when microwave frequency is below 4 GHz, especially for the imaginary part. A model is proposed to explain the formation reason of aligned Fe Si Al composite by this method. Damping factor(α) is calculated by the combination of the effective medium theory and Landau-Lifshitz-Gilbert equation, and the permeability of the samples is verified by these theories.LUO Xiaojia ZHOU Peiheng WANG Xin XIE Jianliang DENG Longjiang 2015Wuhan University Journal of Natural Sciences2015,20,3:2
16Chemopreventive Efficacy and Mechanism of Licofelone in a Mouse Lung Tumor Model via Aspiration heela显示文摘Harma Jin Lee Jianliang Zhou Vernon E 0,,:1
17Characterization and identification of steroidal alkaloids in Ffitillaria species using liquid chromatography coupled with electrospray ionization quadrupole time--of-flight tandem mass spectrometry显示文摘Zhou Jianliang Xin Guizhong Shi Ziqi 2010J Chromatogr A2010,1217,45:1
18Trends in the occurrence of human and veterinary antibiotics in the sediments of the Yellow River, Hai River and Liao River in northern China 显示文摘Zhou Lijun Ying Guangguo Zhao Jianliang 2011Environmental Pollution2011,159,7:1
19Nanocrystalline structure and particle size effect on microwave permeability of FeNi powders prepared by mechanical alloying显示文摘Zhou Peiheng Deng Longjiang Xie Jianliang 2005Magnetism and Magnetic Materials2005,292,:1
20Composition dependence of microstructure,magnetic and microwave properties in ball-milled FeSiB nanocrystalline flakes显示文摘Zhou Peiheng Xie Jianliang Deng Longjiang 2008Journal of Magnetism and Magnetic Materials2008,320,24:1
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