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4篇 您的检索式:作者名="JING Huai Qi"
    题名 作者 年代 出处 被引量
1Expression levels of matrix metalloproteinase-9 in human gastric carcinoma显示文摘Su?Zuan Chen Huai?Qi Yao Sen?Zhi Zhu Qiu?Yuan Li Guang?Hua Guo Jing Yu 2015Oncology Letters2015,,2:1
2Influence of terminal alkyl chain length on helical twisting property of chiral 1,2-propanediol derivatives显示文摘在这研究,有不同终端烷基链长度的 chiral 1,2-propanediol 衍生物的一个新奇系列被英尺红外综合并且描绘, 1 H NMR 和 DSC。在做了进一位 nematic 液体水晶主人以后,所有 chiral 掺杂物导致了与温度变化展出螺旋倒置的 chiral nematic 液体晶体。结果显示那终端烷基链长度在 chiral 掺杂物的螺旋状的扭动的性质上有突出的影响。与增加终端烷基链长度,分子的扭动力量增加,螺旋倒置温度当阶段转变温度减少时,稍微变化。odd–甚至效果可以在 chiral 掺杂物的分子的扭动力量存在。Wei Huang Guang Da Yang Zhen Yu Bian Xiao Juan Wu Guo Jing Ma Qi Huang Huai Yang 2009Chinese Chemical Letters2009,20,12:0
3Comparison of Lipopolysaccharide and Protein Immunogens from Pathogenic Yersinia enterocolitica Bio-serotype 1B/O:8 and 2/O:9 using SDS-PAGE显示文摘Objective Yersinia enterocolitica is an extracellular pathogen and its related antigens interact with the host immune system.We investigated the difference in immunological characteristics between a highly pathogenic and poorly pathogenic strain of Y.enterocolitica.Methods We used SDS-PAGE and western blotting to characterize lipopolysaccharide (LPS),Yersinia outer membrane proteins (Yops),membrane proteins,and whole-cell proteins from poorly pathogenic Y.enterocolitica bio-serotype 2/O:9,isolated from China,and highly pathogenic bio-serotype 1B/O:8,isolated from Japan.Results These two strains of Y.enterocolitica had different LPS immune response patterns.Comparison of their Yops also showed differences that could have accounted for their differences in pathogenicity.The membrane and whole-cell proteins of both strains were similar;immunoblottting showed that the 35 kD and perhaps the 10 kD proteins were immunogens in both strains.Conclusion The major antigens of the two strains eliciting the host immune response were the LPS and membrane proteins,as shown by comparing protein samples with reference and purified preparations.GU Wen Peng WANG Xin QIU Hai Yan LUO Xia XIAO Yu Chun TANG Liu Ying KAN Biao XU Jian Guo JING Huai Qi 2012Biomedical and Environmental Sciences2012,25,3:0
4Dual roles of QOA-8a in antiosteoporosis: a combination of bone anabolic and anti-resorptive effects显示文摘Osteoporotic 处理大部分取决于 antiresorptive 或 anabolism 的药;但是前者也压制新骨头形成,并且后者仅仅包括人的甲状旁腺的荷尔蒙。没有药,有双效果禁止骨头再吞并且同时刺激骨头形成。这里,我们报导一个小分子,在骨质疏松症的处理在造骨细胞和骨破折起如此的双作用的 oleanolic 酸(QOA-8a ) 的 quinoxaline 衍生物。骨破折区别被主要鼠标骨头的孵化导致导出髓的巨噬细胞面对 RANKL 和 M-CSF,有 QOA-8a 的处理 dose-dependently 与 0.098 mol/L 的 IC 50 值禁止了骨破折形成。QOA-8a 直接也对造骨细胞起作用,并且在 vitro 并且在 vivo 在鼠科的 calvarial 骨头刺激了新骨头形成。在一个 OVX 老鼠模型, QOA-8a 的管理(1, 5 mg 楥慮敳 ? 吠??Jing WU Qi SHEN Wei CUI Yu ZHAO Yue HUAI Yu-chao ZHANG Bei-hua BAO Chen-xi LIU Qing JIANG Jian-xin LI 2018Acta Pharmacologica Sinica2018,39,2:0
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