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| 1 | Hepatic steatosis is associated with an increased risk of carotid atherosclerosis显示文摘AIM: Although an association between helatic steatosis and vascular risk factors has been described, direct relationships between fatty liver and atherosclerosis have not yet been investigated. The aim of the present study has been to investigate those relationships.METHODS: The Study of Health in Pomerania examined a random population sample aged between 20 and 79 years.A study population of 4 222 subjects without hepatitis B and C infections and without liver cirrhosis was available for the present analysis. Hepatic steatosis was defined sonographically and intima-media thickness (IMT) as well as plaque prevalence were estimated by carotid ultrasound.RESULTS: The prevalence rate of hepatic steatosis was 29.9%. Among subjects aged ≥45 years, an association between hepatic steatosis and IMT of the carotid arteries was found in bivariate analysis, but not after adjustment for atherosclerotic risk factors. Individuals with fatty liver had more often carotid plaques than persons without fatty liver (plaque prevalence rate 76.8% vs 66.6%; P<0.001).This association persisted after adjustment for confounding factors and was predominantly present in subjects with no to mild alcohol consumption.CONCLUSION: There is an independent association between hepatic steatosis and carotid atherosclerotic plaques. Metabolic changes due to nonalcoholic fatty liver disease may explain this relationship. | Henry V(o|¨)lzke Daniel M.Robinson Volker Kleine Roland Deutscher Wolfgang Hoffmann Jan Lüdemann Ulf Schminke Christof Kessler Ulrich John | 2005 | World Journal of Gastroenterology2005，11，12： | 29 |
| 2 | 固定低剂量三联抗高血压药物与常规治疗对斯里兰卡轻度至中度高血压患者血压控制的疗效差异:一项随机临床试验显示文摘控制不良的高血压是全球领先的公共卫生问题,需要新的治疗策略。该研究评估低剂量三联抗高血压药物治疗是否能达到比常规治疗更好的血压控制。研究者纳入2016年2月至2017年5月在斯里兰卡11所城市医院诊所就诊的需要开始抗高血压治疗(未治疗的患者)或接受单药治疗的患者,进行低剂量三联降压与常规治疗比较的随机、开放性试验,随访至2017年10月。 | Web-ster R Salam A de Silva HA Selak V Stepien S Rajapakse S Amarasekara S Amarasena N Billot L de Silva AP Fernando M Guggilla R Jan S Jayawardena J Maulik PK Mendis S Munasinghe J Naik N Prabhakaran D Ranasinghe G Thom S Tisserra N Senaratne V Wijekoon S Wijeyasingam S Rodgers A Patel A 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 7 |
| 3 | Depression and generalised anxiety in the general population in Belgium: A comparison between native and immigrant groups显示文摘 | Katia L Ina L Jan V | 2007 | J Affect Disord2007，97，1： | 1 |
| 4 | The identification by ^1H and ^13C-nmr spectroscopy of sucrose, 1-kestose, and neokestose in mixtures present in plant extracts显示文摘 | Andre D B Jan V L | 1991 | Carbohydrate Research1991，211，： | 1 |
| 5 | Dimethylsulfoniopropi- onate cleavage by marine phytoplankton in response to mechani- cal,chemical or dark stress显示文摘 | Gordon V W Suzanne L S Jan L H | 2002 | Journal of Phycology2002，38，： | 1 |
| 6 | Development of human protein reference database as an initial platform for approaching systems biology in humans 显示文摘 | PERI S NAVARRO J D AMANCHY R KRISTIANSEN T Z JONNALAGADDA C K SURENDRANATH V NIRAN JAN V MUTHUSAMY B GANDHI T K GRONBORG M IBARROLA N DESHPANDE N SHANKER K SHIVASHANKAR H N RASHMI B P RAMYA M A ZHAO Z CHANDRIKA K N PADMA N HARSHA H C YATISH A J KAVITHA M P MENEZES M CHOUDHURY D R SURESH S GHOSH N SARAVANA R CHANDRAN S KRISHNA S JoY M ANAND S K MADAVAN V JOSEPH A WONG G W SCHIEMANN W P CONSTANTINESCU S N HUANG L KHOSRAVI-FAR R STEEN H TEWARI M GHAFFARI S BLOBE G C DANG C V GARCIA J G PEVSNER J JENSEN O N ROEPSTORFF P DESHPANDE K S CHINNAIYAN A M HAMOSH A CHAKRAVARTI A PANDEY A | 2003 | Genome Research2003，13，10： | 1 |
| 7 | Virtuality, communication, and new product team crea- tivity:a social network perspective显示文摘 | ROGER TH A J LEENDERS J M L V E JAN KRATZ-ER | 2003 | Journal of Engineering and Technology Management2003，，20： | 1 |
| 8 | Optimal training for ML and LMMSE channel estimation in MIMO systems 显示文摘 | GEERT L ALLE JAN V | 2005 | IEEE/SP Statistical Signal Processing2005，，： | 1 |
| 9 | Detection of gas in sandstone reservoirs using AVO analysis: A 3-D seismic case history using the Geostack technique 显示文摘 | Jan L F George C S Peter J V Peter J S Philip R L | 1994 | Geophysics1994，59，： | 1 |
| 10 | Thermodynamics of the liquid Co-Cu system and calculation of phase diagram显示文摘 | Jaroslav Kubi?ta Jan V?e?t’ál | 2000 | Journal of Phase Equilibria2000，，2： | 1 |
| 11 | Methods of protecting buried pipelines and culverts in transportation infrastructure using EPS geofoam显示文摘 | Steven F B Bret N L Jan V | 2015 | Geotextiles and Geomembranes2015，43，： | 1 |
| 12 | Detection of gas in sandstone reservoirs using AVO analysis:A 3-D seismic case history using the Geostack technique显示文摘 | Jan L F George C S Peter J V Peter J S Philip R L | 1994 | Geophysics1994，59，： | 1 |
| 13 | Spiking the MERS-coronavirus receptor显示文摘 | Berend Jan Bosch V Stalin Raj Bart L Haagmans | 2013 | Cell Research2013，23，9： | 1 |
| 14 | Carboxymethylation of inulin显示文摘 | Joop A P Jan G B | 1995 | Carbohydrate Research1995，271，： | 1 |
| 15 | Synthesis and reactions of 1, 1- diamino-2, 2-dinitroethylene 显示文摘 | Nikolai V L Jan Bergman | 1998 | Tetrahedron1998，54，11： | 1 |
| 16 | Reliability and con- struct validity of ultrasonography of soft tissue and destruc- tive changes in erosive, osteoarthritis of the interphalangeal finger joints: a comparison with MRI显示文摘 | Wittoek R Jans L Lambrechi V | 2011 | Annals of the Rheu- matic Diseases2011，70，2： | 1 |
| 17 | Free radicals and antioxidants in normal physiological functions and human disease显示文摘 | MARIAN V DIETER L JAN M | 2007 | Int J Biochem Cell Boil2007，39，： | 1 |
| 18 | The deviation of bullets passing through windowpanes 显示文摘 | Jan D K Serge L W im V L Els De-mu ynck | 2002 | Fo- rensic Science International2002，125，： | 1 |
| 19 | Nutritional responses to the presence of inulin and oligofructose in the diets of domesticated animals: a review显示文摘 | FLICKINGER E A JAN V L FAHEY G C | 2003 | Critical Reviews in Food Science and Nutrition2003，43，1： | 1 |
| 20 | Interactions between soil development, vegetation and soil fauna during spontaneous succession in post mining sites显示文摘 | Jan Frouz Karel Prach Václav Pi?l Ladislav Háněl Josef Stary Karel Tajovsky Jan Materna Vladimír Balík Ji?í Kal?ík Klára ?ehounková | 2007 | European Journal of Soil Biology2007，，1： | 1 |
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