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| 1 | MicroRNA-638 inhibits cell proliferation by targeting phospholipase D1 in human gastric carcinoma显示文摘MicroRNAs (miRNAs ) 是经常是玩的小非编码的 RNA 的一种类型在 carcinogenesis 的重要角色,而是 miRNAs 的 carcinogenic 机制仍然是不清楚的。这研究将在癌(GC ) 调查功能和 miR-638 的机制。在 GC 和 miR-638 的 DNA 拷贝数字的 miR-638 的表示被即时 PCR 检测。房间增长上的 miR-638 的效果被数 kit-8 试金测量。不同试金,包括生物信息学算法(TargetScan 并且人权保护) ,酶报告试金并且西方的弄污,被用来在 GC 识别 miR-638 的目标基因。在临床的 CRC 纸巾的 miR-638 目标基因的表示被 immunohistochemical 试金也验证。从这研究,我们发现 miR-638 与相应 noncancerous 纸巾(NCT ) 相比是在 GC 纸巾的 downregulated,并且 miR-638 的 DNA 拷贝数字比 NCT 在 GC 是更低的,它可以在 GC 导致 miR-638 的相应 downregulation。miR-638 的宫外的表示在 vitro 禁止了 GC 细胞生长。随后,我们鉴别 PLD1 是在 GC,和 silencing PLD1 表示 phenocopied 的 miR-638 的目标基因 GC 房间增长上的 miR-638 的禁止的效果。而且,我们观察到 PLD1 是在在预言的 GC 的 PLD1 的 GC 纸巾,和高表示的 overexpressed 差的全面幸存。在摘要,我们表明 miR-638 通过禁止 PLD1 在 GC 作为肿瘤 suppressor 工作。 | Jiwei Zhang Zehua Bian Jialiang Zhou Mingxu Song Zhihui Liu Yuyang Feng Li Zhe Binbin Zhang Yuan Yin Zhaohui Huang | 2015 | Protein & Cell2015，6，9： | 8 |
| 2 | Effect of mesopores on solidification of sirolimus self-microemulsifying drug delivery system显示文摘To investigate the influence of mesopores towards the solidification of self-microemulsifying drug delivery system(SMEDDS), mesoporous silica nanospheres(MSNs) and Santa Barbara Amorphous-15(SBA-15) were compared. The MSNs had hydrodynamic size of 195.35 ± 5.82 nm, and pore diameter of 2.70 nm. The SBA-15 had hydrodynamic size of 2312.19 ± 106.93 nm, and pore diameter of 10.91 nm. The MSNs and SBA-15 showed similar loading efficiency of SMEDDS containing sirolimus(SRL). However,MSNs had higher drug dissolution and in vivo absorption, with relative bioavailability of 174.62%. Thus,the length of mesopores played a more important role in solidification of SMEDDS as compared with the pore diameter. This study suggests that the SMEDDS-MSNs can be a potential candidate for oral administration of hydrophobic drugs. | Chun Tao Yue Yu Zhenzhen Chen Minxin Zhang Linlin Liu Zhihong Liu Jialiang Zhang Qian Zhang Hongtao Song | 2018 | Chinese Chemical Letters2018，29，12： | 2 |
| 3 | Multi-criteria approach to passive space design in buildings: Impact of courtyard spaces on public buildings in cold climates 显示文摘 | Yehao Song Junjie Li Jialiang Wang ShimengHao Ning Zhu Zhenghao Lin | 2015 | Buildingand Environment2015，，7： | 1 |
| 4 | Redefining the Age of the Cenozoic Shanwang Formation in Shanwang Basin显示文摘Objective The Shanwang Basin is a small Cenozoic sedimentary basin located in Linqu county,Shandong province.The Shanwang Formation,especially the diatomaceous shale member,contains diverse and finely preserved flora and fauna fossils(Fig.1).Previous paleontological study and radiometric dating show that it was formed in the Miocene.However,on the precise age of the formation,there are such different opinions as Late Miocene。 | YU Jifeng ZHAO Xiangguang PANG Xinlong JASON Hilton FU Wenzhao ZHAO Xiuli SONG Zhaojun HU Jialiang LU Lei ZHANG Hongjun YANG Ziqun QIAO Wenyan SHI Suo | 2017 | Acta Geologica Sinica(English Edition)2017，91，4： | 1 |
| 5 | A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts显示文摘 | Ronghui Li Jialiang Liang Su Ni Ting Zhou Xiaobing Qing Huapeng Li Wenzhi He Jiekai Chen Feng Li Qiang Zhuang Baoming Qin Jianyong Xu Wen Li Jiayin Yang Yi Gan Dajiang Qin Shipeng Feng Hong Song Dongshan Yang Biliang Zhang Lingwen Zeng Liangxue Lai Miguel | 2010 | Cell Stem Cell2010，，1： | 1 |
| 6 | Characteristics of the fault-related rocks, fault zones and the principal slip zone in the Wenchuan Earthquake Fault Scientific Drilling Project Hole-1 (WFSD-1)显示文摘 | Haibing Li Huan Wang Zhiqin Xu Jialiang Si Junling Pei Tianfu Li Yao Huang Sheng-Rong Song Li-Wei Kuo Zhiming Sun Marie-Luce Chevalier Dongliang Liu | 2012 | Tectonophysics2012，，： | 1 |
| 7 | A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts显示文摘 | Ronghui Li Jialiang Liang Su Ni Ting Zhou Xiaobing Qing Huapeng Li Wenzhi He Jiekai Chen Feng Li Qiang Zhuang Baoming Qin Jianyong Xu Wen Li Jiayin Yang Yi Gan Dajiang Qin Shipeng Feng Hong Song Dongshan Yang Biliang Zhang Lingwen Zeng Liangxue Lai Miguel | 2010 | Cell Stem Cell2010，，1： | 1 |
| 8 | Durable and recyclable BiOBr/silk fibroin-cellulose acetate composite film for efficient photodegradation of dyes under visible light irradiation显示文摘A stable and recyclable of BiOBr/silk fibroincellulose acetate composite film was prepared by blendingwet phase transformation and in situ precipitate technology.The cellulose acetate film modified by silk fibroin formed a finger-shaped porous structure,which provided a large space for the uniform growth of BiOBr nanosheets and facilitated the shuttle flow of dyes in film.The morphology,phase structure,and optical properties of the composite films were characterized using various techniques,and their photocatalytic performance for dye wastewater was evaluated under visible light irradiation.Results showed that the BiOBr/SF-CA composite film exhibited efficient photocatalytic activity with 99.9%of rhodamine B degradation rate.Moreover,the composite film maintained high catalytic stability because Bi as the active species deposited on the film showed almost no loss.Finally,the possible photocatalytic mechanisms in the BiOBr/SF-CA composite film were speculated through radical-trapping experiments and electron spin resonance testing. | Jialiang Xu Jian Jian Yixiao Dan Jie Song Lingxi Meng Pei Deng Weijie Sun Yusheng Zhang Jinhua Xiong Zhengqiu Yuan Hu Zhou | 2023 | Frontiers of Chemical Science and Engineering2023，17，11： | 0 |
| 9 | National incidence of joint dislocation in China:a retrospective survey of 512,187 individuals显示文摘Background:Joint dislocations significantly impact public health.However,a comprehensive study on the incidence,distribution,and risk factors for joint dislocations in China is lacking.We conducted the China National Joint Dislocation Study,which is a part of the China National Fracture Study conducted to obtain the national incidence and risk factors for traumatic fractures,and to investigate the incidence and risk factors for joint dislocations.Methods:For this national retrospective epidemiological study,512,187 participants were recruited using stratified random sampling and probability-proportional-to-size method from January 19 to May 16,2015.Participants who sustained joint dislocations of the trunk,arms,or legs(skull,sternum,and ribs being excluded)in 2014 were personally interviewed to obtain data on age,educational background,ethnic origin,occupation,geographic region,and urbanization degree.The joint-dislocation incidence was calculated based on age,sex,body site,and demographic factors.The risk factors for different groups were examined using multiple logistic regression.Results:One hundred and nineteen participants sustained 121 joint dislocations in 2014.The population-weighted incidence rate of joint dislocations of the trunk,arms,or legs was 0.22(95%confidence interval[CI]:0.16,0.27)per 1000 population in 2014(men,0.27[0.20,0.34];women,0.16[0.10,0.23]).For all ages,previous dislocation history(male:OR 42.33,95%confidence interval[CI]:12.03-148.90;female:OR 54.43,95%CI:17.37-170.50)and alcohol consumption(male:OR 3.50,95%CI:1.49-8.22;female:OR 2.65,95%CI:1.08-6.50)were risk factors for joint dislocation.Sleeping less than 7 h/day was a risk factor for men.Compared with children,women aged≥15 years(female 15-64 years:OR 0.16,95%CI:0.04-0.61;female≥65 years:OR 0.06,95%CI:0.01-0.41)were less likely to sustain joint dislocations.Women with more than three children were at higher dislocation risk than women without children(OR 6.92,95%CI:1.18-40.78).Conclusions:The up-to-date data on joint dislocation incidence,distribution,and risk factors can be used as a reference for national healthcare,prevention,and management in China.Specific strategies for decreasing alcohol consumption and encouraging adequate sleeping hours should be developed to prevent or reduce dislocation incidents.Trial Registration:Chinese Clinical Trial Registry,ChiCTR-EPR-15005878. | Hongzhi Lv Wei Chen Zhiyong Hou Siming Jia Yanbin Zhu Bo Liu Xiao Chen Guang Yang Lei Liu Tao Zhang Haili Wang Bing Yin Song Liu Jialiang Guo Xiaolin Zhang Yichong Li Yingze Zhang | 2022 | Chinese Medical Journal2022，，14： | 0 |
| 10 | TMEM106A transcriptionally regulated by promoter methylation is involved in invasion and metastasis of hepatocellular carcinoma显示文摘Expression of transmembrane protein 106A(TMEM106A)has been reported to be dysregulated in several types of cancers.However,the role of TMEM106A in hepatocellular carcinoma(HCC)is still unknown.In the present study,we demonstrate that TMEM106A is markedly downregulated in HCC compared with normal liver tissue.In particular,tumor-specific DNA methylation of TMEM106A is frequently observed in tumor tissues from HCC patients.Immunohistochemistry and pyrosequencing reveal a significant relationship between TMEM106A methylation and downregulation of protein expression.Receiver operating characteristic(ROC)curve analysis reveals that methylation of TMEM106A in tumor samples is different from that in non-malignant adjacent tissues of HCC patients.Moreover,HCC patients with TMEM106A hypermethylation have a poor clinical prognosis.5-Aza-2′-deoxycytidin treatment of hypermethylated TMEM106A in highly metastatic HCC cells increases the expression of TMEM106A.Functional assays reveal that overexpression of TMEM106A significantly suppresses the malignant behavior of HCC cells in vitro and decreases tumorigenicity and lung metastasis in vivo.Mechanistically,TMEM106A inhibits epithelial mesenchymal transition(EMT)of HCC cells through inactivation of the Erk1/2/Slug signaling pathway.In conclusion,our findings demonstrate that TMEM106A is an inhibitor of HCC EMT and metastasis,and TMEM106A is often transcriptionally downregulated by promoter methylation,which results in reduced levels of TMEM106A protein and predicts poor survival outcomes for HCC patients. | Shiming Shi Biao Wang Jinglei Wan Lina Song Guiqi Zhu Junxian Du Luxi Ye Qianqian Zhao Jialiang Cai Qing Chen Kun Xiao Jian He Lei Yu Zhi Dai | 2022 | Acta Biochimica et Biophysica Sinica2022，54，7： | 0 |
| 11 | Gold mineralization in Jiaodong Peninsula and destruction of North China Craton:Insights from Mesozoic granite显示文摘Large-scale tectonic magmatism and extensive gold mineralization have occurred in the eastern North China Craton(NCC)(Jiaodong and Liaodong peninsulas)since Mesozoic,which indicated that the region experienced decratonization process.The genesis type of granites evolved from S-type to I-type and A-type during Late Jurassic to Early Cretaceous,and thus reflects the evolution of geodynamics in the Late Mesozoic,indicating the varied subduction process of the Paleo-Pacific Plate(PPP)and the craton destruction.The evolution of geochemical features shows that the mantle beneath the Jiaodong Peninsula evolved from EM-II in Jurassic to EM-I in Early Cretaceous,demonstrating that the mantle switched from enriched to depleted.The gold of decratonic gold deposits in Jiaodong Peninsula mainly comes from the lithospheric mantle domains metasomatized by fluids derived from the metamorphism and dehydration of the subducted slab in the mantle transition zone.The rapid decomposition of minerals leads to the concentrated release of ore-forming fluids,and this process leads to the explosive gold mineralization during the craton destruction.Extensive magmatic uplift and extensional structures,triggered by the craton destruction in Early Cretaceous formed the extensional tectonic system,providing space for the decratonic gold deposits in Jiaodong Peninsula. | WANG Bin ZHOU Jianbo DING Zhengjiang ZHAO Tiqun SONG Mingchun BAO Zhongyi LYU Junyang XU Shaohui YAN Chunming LIU Xiangdong LIU Jialiang | 2023 | Global Geology2023，26，2： | 0 |
| 12 | NUV-pumped luminescence of thermally stable samarium-activated alkali metal borophosphate phosphor显示文摘Exploring outstanding rare-earth activated inorganic phosphors with good thermostability has always been a research focus for high-power white light-emitting diodes(LEDs).In this study,we report a Sm^(3+)-activated KNa_(4)B_(2)P_(3)O_(13)(KNBP)powder phase.Its particle morphology,photoluminescence properties,concentration quenching mechanism,thermal quenching mechanism,and chromatic properties are demonstrated.Upon the near-ultraviolet(NUV)irradiation of 402 nm,the powder phase exhibits orange-red visible luminescence performance,originating from typical ^(4)G_(5/2)→^(6)H_(J/2)(J=5,7,9)transitions of Sm^(3+).Importantly,the photoluminescence performance has good thermostability,low correlated color temperature(CCT),and high color purity(CP),indicating its promising application in the NUV-pumped warm white LEDs. | Zhenyu FANG Dan YANG Youkui ZHENG Jialiang SONG Tongsheng YANG Ruitong SONG Yuefei XIANG Jing ZHU | 2021 | Journal of Advanced Ceramics2021，10，5： | 0 |
| 13 | A Novel Approach for Energy Efficiency Prediction of Various Natural Draft Wet Cooling Towers Using ANN显示文摘Cooling tower is crucial equipment in the cool-end system of power plant and the natural draft counter-flow wet cooling tower(NDWCT)gets wide application.The artificial neural network(ANN)technique is becoming an effective method for the thermal performance investigation of cooling towers.However,the neural network research on the energy efficiency performance of NDWCTs is not sufficient.In this paper,a novel approach was proposed to predict energy efficiency of various NDWCTs by using Back Propagation(BP)neural network:Firstly,based on 638 sets of field test data within 36 diverse NDWCTs in power plant,a three-layer BP neural network model with structure of 8-14-2 was developed.Then the cooling number and evaporation loss of water of different NDWCTs were predicted adopting the BP model.The results show that the established BP neural network has preferable prediction accuracy for the heat and mass transfer performance of NDWCT with various scales.The predicted cooling number and evaporative loss proportion of the testing cooling towers are in good agreement with experimental values with the mean relative error in the range of 2.11%–4.45%and 1.04%–4.52%,respectively.Furthermore,the energy efficiency of different NDWCTs can also be predicted by the proposed BP model with consideration of evaporation loss of water in cooling tower.At last,a novel method for energy efficiency prediction of various NDWCTs using the developed ANN model was proposed.The energy efficiency index(EEI)of different NDWCTs can be achieved readily without measuring the temperature as well as velocity of the outlet air. | SONG Jialiang CHEN Yongdong WU Xiaohong RUAN Shengqi ZHANG Zhongqing | 2021 | Journal of Thermal Science2021，30，3： | 0 |
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