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| 1 | 转录组-代谢组联合分析揭示低温下采后雷竹笋木质化分子调控机制显示文摘雷竹(Phyllostachys violascens)笋是中国传统的山珍之一,是一种天然绿色食品。但其采后易消耗大量水分和营养而快速老化,在一般条件下难以贮藏。文中首次通过“转录组—代谢组”联合分析揭示了低温贮藏条件下雷竹笋木质化的调控机制,研究表明:与常温贮藏相比,低温可显著抑制采后竹笋中PAL、POD酶活性,降低失水率和总木质素含量,从而将竹笋保鲜时间至少延长20 d。通过“转录组—代谢组”联合分析表明,低温下竹笋木质素前体物质、茉莉酸含量呈上升趋势,并在后期显著富集,说明低温可诱导茉莉酸积累、抑制木质素合成。对低温响应、茉莉酸合成和木质素合成通路关键基因进行筛选,并通过共表达分析发现,低温信号可能通过“低温—木质化”和“低温—茉莉酸—木质化”2种通路共同抑制采后竹笋中木质素合成,延缓其保鲜时间。上述结果可为揭示采后竹笋木质化分子调控通路研究提供了一定依据。 | 侯丹(翻译) 林新春(翻译) Haiwen Lu Zhongyu Zhao Jialong Pei Huqing Yang Aimin Wu Xuejun Yu | 2021 | 世界竹藤通讯2021，19，5： | 2 |
| 2 | Highly efficient green InP-based quantum dot light-emitting diodes regulated by inner alloyed shell component显示文摘InP-based quantum dot light-emitting diodes(QLEDs),as less toxic than Cd-free and Pb-free optoelectronic devices,have become the most promising benign alternatives for the next generation lighting and display.However,the development of green-emitting InP-based QLEDs still remains a great challenge to the environmental preparation of InP quantum dots(QDs)and superior device performance.Herein,we reported the highly efficient green-emitting InP-based QLEDs regulated by the inner alloyed shell components.Based on the environmental phosphorus tris(dimethylamino)phosphine((DMA)3P),we obtained highly efficient InP-based QDs with the narrowest full width at half maximum(~35 nm)and highest quantum yield(~97%)by inserting the gradient inner shell layer ZnSe_(x)S_(1-x)without further post-treatment.More importantly,we concretely discussed the effect and physical mechanism of ZnSe_(x)S_(1-x)layer on the performance of QDs and QLEDs through the characterization of structure,luminescence,femtosecond transient absorption,and ultraviolet photoelectron spectroscopy.We demonstrated that the insert inner alloyed shell ZnSe_(x)S_(1-x)provided bifunctionality,which diminished the interface defects upon balancing the lattice mismatch and tailored the energy levels of InP-based QDs which could promote the balanced carrier injection.The resulting QLEDs applying the InP/ZnSe_(0.7)S_(0.3)/ZnS QDs as an emitter layer exhibited a maximum external quantum efficiency of 15.2%with the electroluminescence peak of 532 nm,which was almost the highest record of InP-based pure green-emitting QLEDs.These results demonstrated the applicability and processability of inner shell component engineering in the preparation of high-quallity InP-based QLEDs. | Peng Yu Sheng Cao Yuliang Shan Yuhe Bi Yaqi Hu Ruosheng Zeng Bingsuo Zou Yunjun Wang Jialong Zhao | 2022 | Light(Science & Applications)2022，11，7： | 1 |
| 3 | A homologous and molecular dual-targeted biomimetic nanocarrier for EGFR-related non-small cell lung cancer therapy显示文摘The abnormal activation of epidermal growth factor receptor(EGFR)drives the development of non-small cell lung cancer(NSCLC).The EGFR-targeting tyrosine kinase inhibitor osimertinib is frequently used to clinically treat NSCLC and exhibits marked efficacy in patients with NSCLC who have an EGFR mutation.However,free osimertinib administration exhibits an inadequate response in vivo,with only~3%patients demonstrating a complete clinical response.Consequently,we designed a biomimetic nanoparticle(CMNP^(@Osi))comprising a polymeric nanoparticle core and tumor cell-derived membrane-coated shell that combines membrane-mediated homologous and molecular targeting for targeted drug delivery,thereby supporting a dual-target strategy for enhancing osimertinib efficacy.After intravenous injection,CMNP^(@Osi)accumulates at tumor sites and displays enhanced uptake into cancer cells based on homologous targeting.Osimertinib is subsequently released into the cytoplasm,where it suppresses the phosphorylation of upstream EGFR and the downstream AKT signaling pathway and inhibits the proliferation of NSCLC cells.Thus,this dual-targeting strategy using a biomimetic nanocarrier can enhance molecular-targeted drug delivery and improve clinical efficacy. | Bin Xu Fanjun Zeng Jialong Deng Lintong Yao Shengbo Liu Hengliang Hou Yucheng Huang Hongyuan Zhu Shaowei Wu Qiaxuan Li Weijie Zhan Hongrui Qiu Huili Wang Yundong Li Xianzhu Yang Ziyang Cao Yu Zhang Haiyu Zhou | 2023 | Bioactive Materials2023，，9： | 1 |
| 4 | Autocatalytic reduction-assisted synthesis of segmented porous PtTe nanochains for enhancing methanol oxidation reaction显示文摘Morphology engineering has been developed as one of the most widely used strategies for improving the performance of electrocatalysts.However,the harsh reaction conditions and cumbersome reaction steps during the nanomaterials synthesis still limit their industrial applications.Herein,one-dimensional(1D)novel-segmented PtTe porous nanochains(PNCs)were successfully synthesized by the template methods assisted by Pt autocatalytic reduction.The PtTe PNCs consist of consecutive mesoporous architectures that provide a large electrochemical surface area(ECSA)and abundant active sites to enhance methanol oxidation reaction(MOR).Furthermore,1D nanostructure as a robust sustaining frame can maintain a high mass/charge transfer rate in a long-term durability test.After 2,000 cyclic voltammetry(CV)cycles,the ECSA value of PtTe PNCs remained as high as 44.47 m^(2)·gPt^(-1),which was much larger than that of commercial Pt/C(3.95 m^(2)·gPt^(-1)).The high catalytic activity and durability of PtTe PNCs are also supported by CO stripping test and density functional theory calculation.This autocatalytic reduction-assisted synthesis provides new insights for designing efficient low-dimensional nanocatalysts. | Qiqi Zhang Tianyu Xia He Huang Jialong Liu Mengyuan Zhu Hao Yu Weifeng Xu Yuping Huo Congli He Shipeng Shen Cong Lu Rongming Wang Shouguo Wang | 2023 | Nano Research Energy2023，2，1： | 1 |
| 5 | β Type titanium alloys used in surgical implant materials 显示文摘 | Yu Zhentao Zhou Lian Niu Jialong | 2006 | Rare Metal Materials and Engineering2006，35，： | 1 |
| 6 | Segregation Behaviour and Microstructure of Alloy 718VADER Ingot显示文摘The segregation behaviour and miclostructure of an alloy 718 VADER ingot in comparison with a VAR ingot were studied. The results show that one serious problem of the alloy 718 VADER ingot is dealing with radial chemistry gradients (especially macro-segregation in Nb). The main factor of Nb gradient forming is the flow of Nb rich fluid through passages among the cellular structures driven by centrifugal force from the rotating mold, Detailed structure and micro-segregation studies on ingots impress us that the VADER process does not show the advantage on the improvement of micro-segregation especially in Nb. The cellular structure produced by the VADER process is no more effective in reducjng Nb micro-segregation during homogenization treatment than the dendritic structure by the VAR process. Experimental results lead us to believe that the VADER process is unsuitable to manufacture alloy 718. | Yueguang YU Jie FU and Xishan XIE(University of Science and Technology Bejing, Beijing, 100083, China)Jialong XU and Chunyong JING(Shanghai Iron and Steel Research Institute, Shanghai, 200940, China) | 1994 | Journal of Materials Science & Technology1994，10，6： | 0 |
| 7 | Small molecule interfacial cross-linker for highly efficient two-dimensional perovskite solar cells显示文摘The nonradiative recombination of charge carriers at the hole transport layer(HTL)/perovskite interface generally induces remarkable performance loss of the inverted two-dimensional perovskite solar cells(2D PSCs). Herein, a cross-linkable small molecule of 2-mercaptoimidazole(2-MI) was introduced into the nickel oxide(NiO_(x))/2D perovskite interface. Experiments have confirmed the formation of Ni-N covalent bond by N atom in the 2-MI and Ni in the NiO_(x) and the coordinating between S atom of 2-MI and under-coordinated Pb^(2+) near to the NiO_(x)/perovskite interface, which contributes to creating a crosslinking between NiO_(x)/perovskite interface to restrain charge carrier recombination and enhance the extraction of hole carriers at the interface. Besides, the 2-MI modification layer is also beneficial for promoting the crystallinity of 2D perovskite. Consequently, the inverted 2D PSCs with 2-MI modification achieved the best power conversion efficiency of 15%. This paves a route to acquire highly efficient 2D PSCs by constructing a cross-linking at the NiO_(x)HTL/2D perovskite interface. | Hongming Hou Taotao Hu Fu Zhang Rui Liu Jialong He Chang Liu Yue Yu Dong Chen Qiaofeng Wu Meng Zhang Hua Yu | 2022 | Journal of Energy Chemistry2022，31，5： | 0 |
| 8 | Enhancing low-resource cross-lingual summarization from noisy data with fine-grained reinforcement learning显示文摘Cross-lingual summarization(CLS)is the task of generating a summary in a target language from a document in a source language.Recently,end-to-end CLS models have achieved impressive results using large-scale,high-quality datasets typically constructed by translating monolingual summary corpora into CLS corpora.However,due to the limited performance of low-resource language translation models,translation noise can seriously degrade the performance of these models.In this paper,we propose a fine-grained reinforcement learning approach to address low-resource CLS based on noisy data.We introduce the source language summary as a gold signal to alleviate the impact of the translated noisy target summary.Specifically,we design a reinforcement reward by calculating the word correlation and word missing degree between the source language summary and the generated target language summary,and combine it with cross-entropy loss to optimize the CLS model.To validate the performance of our proposed model,we construct Chinese-Vietnamese and Vietnamese-Chinese CLS datasets.Experimental results show that our proposed model outperforms the baselines in terms of both the ROUGE score and BERTScore. | Yuxin HUANG Huailing GU Zhengtao YU Yumeng GAO Tong PAN Jialong XU | 2024 | Frontiers of Information Technology & Electronic Engineering2024，25，1： | 0 |
| 9 | T790M mutation in stage IV EGFR-mutated NSCLC patient with acquired resistance reverted to original 19Del mutation after administration of a series of precision treatments:a case report显示文摘Existing studies have yet to elucidate clearly the mechanisms of secondary resistance to third generation epidermal growth factor receptor(EGFR)tyrosine kinase inhibitors(TKIs),neither is there any established standard therapy for patients resistant to third generation EGFR-TKIs.This case report demonstrates a rare mutation pattern in a male patient with a pathologic diagnosis of non-small cell lung cancer(NSCLC)harboring an EGFR exon 19 deletion(19Del)mutation,who then acquired an EGFR-T790M mutation after developing resistance to the first generation EGFR-TKI(gefitinib).The mutation reverted to the original EGFR-19Del mutation after the patient developed secondary resistance against the third generation TKI(osimertinib).This patient eventually achieved partial response(PR)with second generation TKI(afatinib)as a fourth-line treatment. | Jialong Han Ya Wang Lili Zhong Huijie Zhou Min Yu Yanying Li You Lu Yan Wang Jiang Zhu | 2018 | Precision Clinical Medicine2018，1，3： | 0 |
| 10 | Boosting electroluminescence performance of all solution processed In P based quantum dot light emitting diodes using bilayered inorganic hole injection layers显示文摘The development of high-performance In P-based quantum dot light-emitting diodes(QLEDs)has become the current trend in ecofriendly display and lighting technology.However,compared with Cd-based QLEDs that have already been devoted to industry,the efficiency and stability of In P-based QLEDs still face great challenges.In this work,colloidal Ni Oxand Mg-doped Ni Oxnanocrystals were used to prepare a bilayered hole injection layer(HIL)to replace the classical polystyrene sulfonate(PEDOT:PSS)HIL to construct high-performance In Pbased QLEDs.Compared with QLEDs with a single HIL of PEDOT:PSS,the bilayered HIL enables the external quantum efficiencies of the QLEDs to increase from 7.6%to 11.2%,and the T_(95)lifetime(time that the device brightness decreases to 95%of its initial value)under a high brightness of 1000 cd m^(-2)to prolong about 7 times.The improved performance of QLEDs is attributed to the bilayered HIL reducing the mismatched potential barrier of hole injection,narrows the potential barrier difference of indium tin oxide(ITO)/hole transport layer interface to promote carrier balance injection,and realizes high-efficiency radiative recombination.The experimental results indicate that the use of bilayered HILs with p-type Ni Oxmight be an efficient method for fabricating high-performance In P-based QLEDs. | QIUYAN LI SHENG CAO PENG YU MEIJING NING KE XING ZHENTAO DU BINGSUO ZOU JIALONG ZHAO | 2022 | Photonics Research2022，10，9： | 0 |
| 11 | Preparation of Ag3PO4/AgBr Hybrids Using a Facile Grinding Method and Their Applications as Photocatalysts显示文摘 | ZHANG Xiaojun YAN Keqiang SONG Yu WANG Zhe WU Jialong YU Dayu | 2018 | Chemical Research in Chinese Universities2018，34，4： | 0 |
| 12 | Self-templating synthesis of Pd_(4)S hollow nanospheres as electrocatalysts for oxygen reduction reaction显示文摘Hollow nanostructures with structural advantages have been widely exploited as catalysts in electrochemical reactions.However,there are only limited strategies for constructing hollow Pd-based nanostructures.In this work,Pd4S hollow nanospheres(Pd4S HNSs)are synthesized with a facile wet-chemical method via a self-templating process.Intermediate Pd-L-cysteine solid nanospheres(SNSs)were firstly obtained by the coordination of L-cysteine with Pd^(2+),and then in situ converted to hollow nanospheres in the following reduction process.The formation mechanism of the Pd4S HNSs was studied,and the size of the Pd4S HNSs can be readily adjusted by tuning the size of the SNSs.The hollow morphology would help the exposure of active sites and the prevention of aggregation during the catalytic reactions.As a result,the Pd4S HNSs exhibit improved catalytic performances in the oxygen reduction reactions,with a half-wave potential of 0.913 V vs.reversible hydrogen electrode(RHE)and impressive stability in the accelerated durability test. | Qian Wang Donghui Zhao Jialong Yu Lijie Shi Yawen Wang Hongyu Chen | 2023 | Nano Research2023，16，2： | 0 |
| 13 | Modulating the alloying mode in the doping-induced synthesis of Au-Pd nanowires显示文摘Heterogeneous doping is one effective strategy for synthesizing metal alloy nanowires.Herein,the heterogeneous doping processes of Pd on the ultrathin Au nanowires were systematically modulated and investigated.Au-Pd alloy nanowires with various morphologies and lattice structures can be obtained by adjusting the morphology of the precursor Au nanowires and the kinetics of the heterogeneous doping processes.The effects of the rate of Pd reduction and the concentration of the ligand oleylamine(OAm)on the Pd deposition and alloying mode were articulated.Generally,as the Pd deposition rate decreases,the Pd deposition and alloying mode switches from the island-forming Stransky–Krastanov(SK)mode to the epitaxial Frank-van der Merwe(FM)mode,and eventually to an unconventional twisting alloying mode,where the interdiffusion of Pd and Au causes drastic rearrangement of the lattice structure and formation of helical structures.The kinetics-related variation of alloying mode could also be observed in the Au-Ag nanowires,demonstrating a general design principle for the synthesis of alloy nanostructures.In addition,the electrocatalytic performance of various Au-Pd nanowires was evaluated,and the alloy nanowire formed via the SK mode was found to be an excellent electrocatalyst for oxygen reduction and ethanol oxidation. | Hui Jin Xiaoliang Wei Lecheng Zhao Jialong Yu Qiao Pan Shumin Li Qian Wang Zhaotong Yuan Dan Yang Donghui Zhao Hongyu Chen Yawen Wang | 2024 | Nano Research2024，17，4： | 0 |
| 14 | Well-aligned Ni Pt alloy counter electrodes for high-efficiency dye-sensitized solar cell applications显示文摘Development of cost-effective and robust counter electrodes(CEs) is a persistent objective for highefficiency dye-sensitized solar cells(DSSCs). To achieve this goal, we present here the hydrothermal synthesis of well-aligned Ni Pt alloy CEs, which is templated by ZnO nanowires and nanosheets. The preliminary results demonstrate that Ni Pt alloy electrodes are featured by increased charge-transfer processes and electrocatalytic activity in comparison with expensive Pt CE, yielding power conversion efficiencies of 8.29% and 7.41% in corresponding DSSCs with Ni Pt nanowire and nanosheet alloy CEs, respectively. Additionally, the Ni Pt alloy CEs also display extraordinary dissolution-resistant ability when suffering longterm utilization in liquid-junction DSSCs. | Zhibin Pang Yuanyuan Zhao Yanyan Duan Jialong Duan Qunwei Tang Liangmin Yu | 2019 | Journal of Energy Chemistry2019，28，3： | 0 |
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