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| 1 | Soil salinization research in China: Advances and prospects显示文摘与气候变化的进展引起的环境恶化,土壤 salinization 是一个严重、成长的全球问题。当前,大约 7% 世界陆地表面被 salinization 威胁。中国是其土壤被这个问题严重地影响的一个国家,它由于它的广泛的区域,并且宽分发形成严肃的威胁到地区性的农业开发。在这评论,我们在过去的 70 年在中国为土壤 salinization 研究总结框架,估计存在的软弱在两个研究国内、国际的上下文,加亮趋势并且给关于在过去的 30 年的盐的土壤的全球研究的调查结果调音,并且为关于盐的土壤的未来研究建议六个主要领域和方向。 | LI Jianguo PU Lijie HAN Mingfang ZHU Ming ZHANG Runsen XIANG Yangzhou | 2014 | Journal of Geographical Sciences2014，24，5： | 90 |
| 2 | 125I seed implant brachytherapy-assisted surgery with preservation of the facial nerve for treatment of malignant parotid gland tumors显示文摘 | Jianguo Zhang Jie Zhang | 2008 | 中国口腔颌面外科杂志2008，6，B05： | 53 |
| 3 | Variations between rice cultivars in iron and manganese plaque on roots and the relation with plant cadmium uptake显示文摘To understand certain mechanisms causing variations between rice cultivars with regard to cadmium uptake and tolerance,pot soil experiments were conducted with two rice cultivars of different genotypes under different soil Cd levels.The relationships between plant Cd uptake and iron/manganese(Fe/Mn) plaque formation on roots were investigated.The results showed that rice cultivars di?ered markedly in Cd uptake and tolerance.Under soil Cd treatments,Cd concentrations and accumulations in the cultivar Shanyou 63(the genotype indica) were significantly higher than those in the cultivar Wuyunjing 7(the genotype japonica)(P < 0.01,or P < 0.05),and Shanyou 63 was more sensitive to Cd toxicity than Wuyunjing 7.The differences between the rice cultivars were the largest at relatively low soil Cd level(i.e.,10 mg/kg).Fe concentrations in dithionite-citrate-bicarbonate root extracts of Shanyou 63 were generally lower than that of Wuyunjing 7,and the difference was the most significant under the treatment of 10 mg Cd/kg soil.The results indicated that the formation of iron plaque on rice roots could act as a barrier to soil Cd toxicity,and may be a 'buffer' or a 'reservoir' which could reduce Cd uptake into rice roots.And the plaque may contribute,to some extent,to the genotypic differences of rice cultivars in Cd uptake and tolerance. | Jianguo Liu Changxun Cao Minghung Wong Zhijun Zhang Yuhong Chai | 2010 | Journal of Environmental Sciences2010，22，7： | 43 |
| 4 | The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage显示文摘在应力之上,肿瘤 suppressor p53 的水平显著地被提高,是众所周知的。然而尽管有广泛的研究,包含的内在的机制重要为导致压力的 p53 规定内部播放器仍然不充分被理解。我们人的 lincRNA-RoR (RoR ) 是 p53 的一个强壮的否定管理者的现在的证据。不同于通过 ubiquitin-proteasome 小径引起 p53 降级的 MDM2, RoR 通过和异构的原子 ribonucleoprotein 的直接相互作用压制 p53 翻译我(hnRNP 我) 。重要地,带 hnRNP 的一个 28 底 RoR 序列我有约束力的主题为 p53 压抑必要、足够。我们进一步证明 RoR 禁止调停 p53 的房间周期拘捕和 apoptosis。最后,我们表明 p53 transcriptionally 导致 RoR 表示的一个 RoR-p53 自动调整的反馈环。一起,这些结果建议 RoR-hnRNP I-p53 轴可以组成一个另外的监视网络让房间更好对各种各样的压力作出回应。 | Ali Zhang Nanjiang Zhou Jianguo Huang Qian Liu Koji Fukuda Ding Ma Zhaohui Lu Cunxue Bai Kounosuke Watabe Yin-Yuan Mo | 2013 | Cell Research2013，23，3： | 47 |
| 5 | Why Lake Taihu continues to be plagued with cyanobacterial blooms through 10 years(2007–2017) efforts显示文摘With the expansion of urban, industry, and agriculture after World War II, eutrophication firstly emerged as a major water quality threat in small water bodies [1]. As the increasing magnitudes and scales of nutrient pollution and habitat alteration, many of the world's large lakes exhibit symptoms of eutrophication, e.g., toxic cyanobacterial blooms, deoxygenation, and habitat loss. | Boqiang Qin Hans W.Paerl Justin D.Brookes Jianguo Liu Erik Jeppesen Guangwei Zhu Yunlin Zhang Hai Xu Kun Shi Jianming Deng | 2019 | Science Bulletin2019，64，6： | 50 |
| 6 | Fuzzy interface treatment in Eulerian method显示文摘In this paper, we incorporate fuzzy mathematics approach into the Eulerian method to simulate three dimensional multi-material interfaces. In particular, we propose a fuzzy interface treatment for describing interfaces, designing transport plans, and computing transport quantities. Using a set of three-dimensional inviscid isothermal elastic-plastic hydrodynamic equations, we simulate shaped charge jet in different filled dynamite structures. Strain and stress have been under consideration in simulations. Numerical results demonstrate that the fuzzy interface treatment is correct and efficient for three-dimensional multi-material problems. | NING Jianguo1 & CHEN Longwei1,2 1. National Key Laboratory of Protection and Control of Explosive Disaster, Beijing Institute of Technology, Beijing 100081, China 2. The Faculty of Land Resource Engineering, Kunming University of Science and Technology, Kunming 650093, China Correspondence should be addressed to Ning Jianguo | 2004 | Science China(Technological Sciences)2004，47，5： | 40 |
| 7 | Microsatellite analysis of genetic diversity and population structure of Chinese mitten crab (Eriocheir sinensis)显示文摘中国露指手套螃蟹(Eriocheir sinensis ) 在中国比 Eriocheir 的任何另外的种类作为食物来源有更高商业的价值。为了评估细菌原生质资源并且在不同的水系统,二张股票和二张耕作人口描绘基因差异和螃蟹的人口结构,与在公共场合可得到的 25 多态的 microsallite loci 被估计 GenBank。基本统计证明一般水准观察了杂合现象(惊讶) 在人口之中从 0.5789 ~ 0.6824 。然而,使近交的显著存在和异质接合体缺乏被观察。到分析人口结构,配对系数从露指手套螃蟹人口的分向仅仅 10.3% 可变性解释了的明智的 FST,留下的可变性在潜水艇人口以内源自分。尽管四张人口有细微区别,不同突变而产生之遗传的频率导致了不同人口结构。二张股票和股票耕作人口一起被聚类到 Yangtze 螃蟹的种系发生的分支,与 95% 的一个近似会员。而,另一张耕作人口单身地被聚类到 Liaohe 螃蟹的种系发生的分支,与 97.1% 的一个会员。为单个混合的测试证明那只 Yangtze 螃蟹可能从另外的水系统与个人一起被污染了。在人口之间的基因关系也支持了尽管有一样的种类的起源,那只 Yangtze 螃蟹和 Liaohe 螃蟹有不同基因库的结论。 | Yumei Chang Liqun Liang Haitao Ma Jianguo He Xiaowen Sun | 2008 | Journal of Genetics and Genomics2008，35，3： | 29 |
| 8 | FOXA2 functions as a suppressor of tumor metastasis by inhibition of epithelial-to-mesenchymal transition in human lung cancers显示文摘forkhead 盒子抄写因素 A2 (FOXA2 ) 是在动物开发和身体动态平衡的一个重要管理者。然而, FOXA2 是否涉及转变生长因素尾 1 (TGF-尾 1 ) ,调停了 epithelial-to-mesenchymal 转变(EMT ) 和肿瘤转移仍然保持未知。现在的学习证明在人的肺癌症房间线,许多 FOXA2 断然与上皮的显型相关并且否定地与房间的间充质的显型相关,并且 TGF-尾 1 治疗减少了 FOXA2 蛋白质水平。一致地, FOXA2 击倒肺癌症房间的支持的 EMT 和侵略,而 FOXA2 的 overexpression 减少了侵略并且压制了 TGF- ,尾 1 导致了 EMT。另外, FOXA2 击倒禁止的 FOXA2 的导致的蛞蝓表示,和宫外的表示猛击抄写。而且,我们鉴别 FOXA2 能绑通过一个保存有约束力的地点猛击倡导者,并且 FOXA2 的 DNA 有约束力的区域和 transactivation 区域 II 为蛞蝓倡导者的压抑被要求。这些数据证明 FOXA2 由 EMT 的抑制作为肿瘤转移的 suppressor 工作。 | Yunneng Tang Guangwen Shu Xinwang Yuan Naihe Jing Jianguo Song | 2011 | Cell Research2011，21，2： | 27 |
| 9 | Suppression of Jasmonic Acid-Mediated Defense by Viral-Inducible MicroRNA319 Facilitates Virus Infection in Rice显示文摘MicroRNAs (miRNAs ) 是植物开发和主人病毒相互作用的枢轴的调节的人。然而,角色和涉及病毒的感染和主人危险性的特定的 miRNAs 的行动模式仍然保持大部分不清楚。在这研究,我们给那瑞斯看引起 miR319 的增加的累积,但是减少的破旧绝技病毒(RRSV ) 感染调整 miR319 的 TCP (TEOSINTE BRANCHED/CYCLOIDEA/PCF ) 的表示基因,特别 TCP21,在米饭植物。转基因的米饭植物 overexpressing miR319 或 downregulating TCP21 展出了像疾病的显型并且与野类型的植物比较显示出显著地更高的危险性到 RRSV。相反,仅仅温和的疾病症状在感染 RRSV 的线 overexpressing TCP21 并且特别在转基因的植物 overexpressing 被观察 miR319 抵抗的 TCP21。miR319 的 RRSV 感染和 overexpression 在米饭与 JA 生合成和信号相关的基因的 downregulated 表示一起引起了减少的内长的 jasmonic 酸(JA ) 层次。然而,有甲基 jasmonate 的米饭植物的治疗减轻了 RRSV 引起并且减少了病毒累积的疾病症状。一起拿,我们的结果建议由在米饭的 RRSV 感染的 miR319 的正式就职压制调停 JA 的防卫便于病毒感染和症状开发。 | Chao Zhang Zuomei Ding Kangcheng Wu Liang Yang Yang Li Zhen Yang Shan Shi Xiaojuan Liu Shanshan Zhao Zhirui Yang Yu Wang Luping Zheng Juan Wei Zhenguo Du Aihong Zhang Hongqin Miao Yi Li Zujian Wu Jianguo Wu | 2016 | Molecular Plant2016，9，9： | 27 |
| 10 | Effect of Lichong decoction on expression of Bcl-2 and Bcl-2-associated X protein mRNAs in hysteromyoma model rat显示文摘OBJECTIVE:To study on effects of Lichong decoction on expression of apoptosis-controlling genes,Bcl-2 and Bcl-2-associated X protein(Bax) mRNAs in hysteromyoma tissue of the hysteromyoma model rat.METHODS:Fifty Wistar female rats were randomly divided into a normal group,a model group,a Lichong decoction group,a Guizifuling capsule group and a Mifepristone group.The hysteromyoma rat model was established by intraperitoneal injection of exogenous estrin and progestogens.Pathological examination of uterine tissue,uterine coefficient and uterine transverse diameter were made under optic microscope and expressions of Bcl-2 and Bax mRNAs in uterine tissue in the groups were detected with real-time fluorescent quantitative polymerase chain reaction(PCR) technique.RESULTS:After treatment,under microscope it was found that in the Lichong decoction group myometrium thinned,muscle fiber slightly overgrowth or long and thin,regular arrangement,inserting phenomenon of inner circular muscle and external longitudinal muscle was occasionally or not seen in the Lichong decoction group.The uterine coefficient and the uterine transverse diameter significantly decreased(P<0.01),and Bcl-2 mRNA expression significantly decreased(P<0.01) and Bax mRNA expression significantly increased in hysteromyoma tissue(P<0.01) in the Lichong decoction group as compared with the model group.CONCLUSION:Therapeutic effects of Lichong decoction on hysteromyoma is related with decrease of Bcl-2 mRNA expression and increase of Bax mRNA expression. | Donghua Li Xin Xu Ruiya Qian Jianguo Geng Yan Zhang Xiaolei Xie Yasong Wang Xiaoli Zou | 2013 | Journal of Traditional Chinese Medicine2013，33，2： | 24 |
| 11 | Dynamic dam-reservoir interaction analysis including effect of reservoir boundary absorption显示文摘Based on the scaled boundary finite-element method, the governing equations for the analysis of dam-reservoir interaction including the reservoir boundary absorption are developed. Coupling with the equation of dam-unbounded foundation interaction, it can effectively carry out the earthquake response analysis of dameservoir-foundation system. The proposed approach has the advantages that the effect of compressibility of reservoir water as well as the energy absorption of reservoir boundary on the earthquake response of arch dams and gravity dams can be efficiently evaluated and higher accuracy can be achieved. In comparison with the methods available in the literature, the computational cost can be reduced to a great extent. It facilitates the application of earthquake response analysis of dam-reservoir-foundation system including reservoir boundary absorption to the engineering practice. | LIN Gao DU JianGuo HU ZhiQiang | 2007 | Science China(Technological Sciences)2007，50，z1： | 23 |
| 12 | Behavior of composite rigid frame bridge under bi-directional seismic excitations显示文摘Pushover analysis and time history analysis are conducted to explore the bi-directional seismic behavior of composite steel-concrete rigid frame bridge,which is composed of RC piers and steel-concrete composite girders.Both longitudinal and transverse directions excitations are investigated using OpenSees.Firstly,the applicability of pushover analysis based on the fundamental mode is discussed.Secondly,an improved pushover analysis method considering the contribution of higher modes is proposed,and the applicability on composite rigid frame bridges under bi-directional earthquake is verified.Based on this method,an approach to predict the displacement responses of composite rigid frame bridge under random bi-directional seismic excitations by revising the elasto-plastic demand curve is also proposed.It is observed that the developed method yield a good estimate on the responses of composite rigid frame bridges under bi-directional seismic excitations. | Xiaogang Liu Jiansheng Fan Jianguo Nie Guo Li | 2014 | Journal of Traffic and Transportation Engineering(English Edition)2014，1，1： | 22 |
| 13 | Identification of long-range transport pathways and potential sources of PM2.5 and PM10 in Beijing from 2014 to 2015显示文摘Trajectory clustering, potential source contribution function(PSCF) and concentration-weighted trajectory(CWT) methods were applied to investigate the transport pathways and identify potential sources of PM_(2.5)and PM_(10) in different seasons from June 2014 to May 2015 in Beijing.The cluster analyses showed that Beijing was affected by trajectories from the south and southeast in summer and autumn. In winter and spring, Beijing was not only affected by the trajectories from the south and southeast, but was also affected by trajectories from the north and northwest. In addition, the analyses of the pressure profile of backward trajectories showed that backward trajectories, which have important influence on Beijing, were mainly distributed above 970 h Pa in summer and autumn and below 950 h Pa in spring and winter. This indicates that PM_(2.5)and PM_(10) were strongly affected by the near surface air masses in summer and autumn and by high altitude air masses in winter and spring. Results of PSCF and CWT analyses showed that the largest potential source areas were identified in spring, followed by winter and autumn,then summer. In addition, potential source regions of PM_(10) were similar to those of PM_(2.5). There were a clear seasonal and spatial variation of the potential source areas of Beijing and the airflow in the horizontal and vertical directions. Therefore, more effective regional emission reduction measures in Beijing's surrounding provinces should be implemented to reduce emissions of regional sources in different seasons. | Deping Li Jianguo Liu Jiaoshi Zhang Huaqiao Gui Peng Du Tongzhu Yu Jie Wang Yihuai Lu Wenqing Liu Yin Cheng | 2017 | Journal of Environmental Sciences2017，29，6： | 22 |
| 14 | Landscape of emerging and re-emerging infectious diseases in China: impact of ecology, climate, and behavior显示文摘为过去的几十年,在中国的传染疾病侧面在社会、经济的方面,环境,食物的质量,水,住房,和公共健康基础结构与快速的开发一直在变。尤其是, 5 应具报的传染疾病几乎被根除了,并且 18 另外的应具报的传染疾病的发生显著地被减少了。出人意料地,包括 HIV,普鲁斯病,梅毒,和登革热发烧,超过 10 应具报的传染疾病的发生一直在增加。不过,经常的传染疾病爆发 / 事件每年几乎被报导了,并且进口了传染疾病自从 2015,增加了。已知的病原体的新病原体和超过 100 新遗传型或 serotypes 被识别了。一些传染疾病似乎被各种各样的因素加重,包括快速的都市化,大量候鸟工人,在气候的变化,生态学,和政策,例如把农田还给森林。这评论在设法出现和 re-emerging 从中国总结当前的经验和课传染疾病,特别生态学的效果,气候,和行为,它应该在帮助另外的国家控制并且阻止传染疾病有优点。 | Qiyong Liu Wenbo Xu Shan Lu Jiafu Jiang Jieping Zhou Zhujun Shao Xiaobo Liu Lei Xu Yanwen Xiong Han Zheng Sun Jin Hai Jiang Wuchun Cao Jianguo Xu | 2018 | Frontiers of Medicine2018，12，1： | 23 |
| 15 | A novel method for purification of recombinant adeno-associated virus vectors on a large scale显示文摘A novel method for recombinant adeno-associ-ated virus (rAAV) purification on large scale is described. The method involves three steps, including chloroform treatment, PEG/NaCl precipitation and chloroform extraction. The whole procedure can be performed in four hours. Using this purification method, we can reproducibly obtain, from 4 × 109 of proviral cells cultured in roller bottles, purified rAAV-GFP stocks with titers of around 5×1013 particles/mL and purity greater than 95%. The infectious titers of the vector stocks were up to 2×1012 TU/mL, thus particle-to-infectivity rate was about 25. Under an electronic microscope, most rAAV particles appeared full and a few were in intermediate form. Empty particles were rarely seen. The purified rAAV-GFP stocks have been successfully used in in vitro and in vivo transfection experiments. Therefore, this new method offers a simple, rapid and cost-effective way for large-scale rAAV purification. | WU Xiaobing DONG Xiaoyan WU Zhijian CAO Hui NIU Dongbin QU Jianguo WANG Hong HOU Yunde | 2001 | Chinese Science Bulletin2001，46，6： | 21 |
| 16 | An alternative therapy for drug-resistant epilepsy: transcutaneous auricular vagus nerve stimulation显示文摘 | Rong Peijing Liu Aihua Zhang Jianguo Wang Yuping Yang Anchao Li Liang Ben Hui Li Liping Liu Rupeng He Wei Liu Huanguang Huang Feng Li Xia Wu Peng Zhu Bing | 2014 | Chinese Medical Journal2014，，2： | 20 |
| 17 | Cold adaptation in pigs depends on UCP3 in beige adipocytes显示文摘 | Jun Lin Chunwei Cao Cong Tao Rongcai Ye Meng Dong Qiantao Zheng Chao Wang Xiaoxiao Jiang Guosong Qin Changguo Yan Kui Li John R. Speakman Yanfang Wang Wanzhu Jin Jianguo Zhao | 2017 | Journal of Molecular Cell Biology2017，9，5： | 20 |
| 18 | Genome Analysis of the Ancient Tracheophyte Selaginella tama#scina Reveals Evolutionary Features Relevant to the Acquisition of Desiccation Tolerance显示文摘 | Zhichao Xu Tianyi Xin Dorothea Bartels Ying Li Wei Gu Hui Yao Sai Liu Haoying Yu Xiangdong Pu Jianguo Zhou Jiang Xu Caicai xi Hetian Lei Jingyuan song Shilin Chen | 2018 | Molecular Plant2018，11，7： | 20 |
| 19 | Lunar topographic model CLTM-s01 from Chang’E-1 laser altimeter显示文摘More than 3 million range measurements from the Chang’E-1 Laser Altimeter have been used to produce a global topographic model of the Moon with improved accuracy. Our topographic model, a 360th degree and order spherical harmonic expansion of the lunar radii, is designated as Chang’E-1 Lunar Topography Model s01 (CLTM-s01). This topographic field, referenced to a mean radius of 1738 km, has an absolute vertical accuracy of approximately 31 m and a spatial resolution of 0.25o (~7.5 km). This new lunar topographic model has greatly improved previous models in spatial coverage, accuracy and spatial resolution, and also shows the polar regions with the altimeter results for the first time. From CLTM-s01, the mean, equatorial, and polar radii of the Moon are 1737103, 1737646, and 1735843 m, respectively. In the lunar-fixed coordinate system, this model shows a COM/COF offset to be (-1.777, -0.730, 0.237) km along the x, y, and z directions, respectively. All the basic lunar shape parameters derived from CLTM-s01 are in agreement with the results of Clementine GLTM2, but CLTM-s01 offers higher accuracy and reliability due to its better global samplings. | PING JinSong HUANG Qian YAN JianGuo CAO JianFeng TANG GeShi SHU Rong | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，7： | 19 |
| 20 | Mechanical mechanism of overlying strata breaking and development of fractured zone during close-distance coal seam group mining显示文摘This study mainly investigates the mechanical mechanism of overlying strata breaking and the development of fractured zones during close-distance coal seam group mining in the Gaojialiang coal mine.First,a mechanical model for the second'activation'of broken overlying strata is established,and the related mechanical'activation'conditions are obtained.A recursive formula for calculating the separation distance of overlying strata is deduced.Second,a height determining method for predicting the height of fractured zones during close-distance coal seam group mining is proposed based on two values,namely,the separation distance and ultimate subsidence value of overlying strata.This method is applied to calculate the fractured zone heights in nos.20107 and 20307 mining faces.The calculated results are almost equal to the field observation results.Third,a modified formula for calculating the height of a waterflowing fractured zone is proposed.A comparison of the calculated and observed results shows that the errors are small.The height determining method and modified formula not only build a theoretical foundation for water conservation mining at the Gaojialiang coal mine,but also provide a reference for estimating the height of water-flowing fractured zones in other coal mines with similar conditions. | Jianguo Ning Jun Wang Yunliang Tan Qiang Xu | 2020 | International Journal of Mining Science and Technology2020，30，2： | 19 |
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