|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of myosin heavy chain composition of muscles on meat quality in Laiwu pigs and Duroc显示文摘In order to explain the mechanism of high meat quality in Laiwu pigs and investigate the relation between myosin heavy chains (MyHC) composition and meat quality, meat quality analysis was conducted and mRNA expression of MyHC I, IIa, IIx, IIb was quantified by real-time fluorescence PCR in longissimus muscle (LM) and semimembranous muscle of Laiwu pigs and Duroc. The result indicated that, compared with Duroc, mRNA expression of MyHC IIa, IIx in LM and semimembranous muscle of Laiwu pigs was significantly increased, mRNA expression of MyHC IIb was dramatically decreased. However, the expression of MyHC I was not significantly affected by breeds. The correlation between mRNA expression of MyHC I, IIa, IIx in LM and meat color, pH value, marbling, intramuscular fat content was positive, but shear value of LM was negative. The relation between MyHC IIb mRNA expression and marbling, intramuscular fat content was dramatically negative, whereas shear value was strikingly positive, as well as fiber diameter, but without reaching statistical significance. Therefore, the composition of MyHC I, IIa, IIx, IIb affected meat quality, furthermore, expression of MyHC I, IIa, IIx, IIb mRNA prominently influenced meat characteristics, especially edible quality of muscle, suggesting that mRNA expression level of MyHC I, IIa, IIx, IIb can exactly and impersonally estimate meat quality. | HU HongMei, WANG JiYing, ZHU RongSheng, GUO JianFeng & WU Ying Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan 250100, China | 2008 | Science China(Life Sciences)2008，51，2： | 26 |
| 2 | Exosome-mediated transfer of miR-1290 promotes cell proliferation and invasion in gastric cancer via NKD1显示文摘Currently, exosomes rich in RNAs and proteins are regarded as vital mediators of intercellular communication. Here, we aimed to explore the effects of exosomal miR-1290 in gastric cancer (GC) and understand its mechanism of action on GC progression. We first isolated exosomes from serum samples of GC patients and healthy people and characterized them by transmission electron microscopy. Then, we examined the expression level of miR-1290 contained in the exosomes by quantitative reverse-transcription polymerase chain reaction and found that exosomal miR-1290 was overexpressed in GC patients and cell lines. Promotion of proliferation, migration, and invasiveness of GC cells was noted after they were incubated with the isolated miR-1290-rich exosomes compared with incubation with a negative control. Furthermore, we predicted that naked cuticle homolog 1 (NKD1) mRNA is a direct target of miR-1290 and confirmed their interaction by a dual luciferase reporter assay. NKD1 overexpression attenuated the stimulatory effects of miR-1290 on GC cells. Collectively, our results suggest that exosomal miR-1290 enhances GC cell proliferation and invasion by targeting NKD1 mRNA and downregulating NKD1 expression. A better understanding of this process may facilitate the development of novel therapeutic agents for GC. | Jiying Huang Manru Shen Meizhu Yan Ying Cui Zhenjun Gao Xin Meng | 2019 | Acta Biochimica et Biophysica Sinica2019，51，9： | 19 |
| 3 | Antigen-presenting effects of effector memory Vγ9Vδ2 T cells in rheumatoid arthritis显示文摘 | Chaoying Hu Liu Qian Yi Miao Qiuyu Huang Ping Miao Ping Wang Qiwen Yu Hong Nie Jiying Zhang Dongyi He Rong Xu Xuehua Chen Bingya Liu Dongqing Zhang | 2012 | Cellular & Molecular Immunology2012，9，3： | 18 |
| 4 | Vision,application scenarios,and key technology trends for 6G mobile communications显示文摘With the global commercialization of the fifth-generation(5G)network,many countries,including China,USA,European countries,Japan,and Korea,have started exploring 6G mobile communication network,following the tradition of“planning the next while commercializing one generation”.Currently,studies on 6G networks are at the infancy stage.Research on the vision and requirements for 6G is still ongoing,and the industry is yet to clarify the key enabling technologies for 6G.However,6G will certainly build on the success of 5G.Therefore,developing high-quality 5G networks and seamlessly integrating 5G with verticals are the priorities before 2030,when 6G is projected to be commercialized.Also,global 5G standards will keep evolving to better support vertical applications.As a milestone,the Third-Generation Partnership Project(3GPP)published Release 16 in July 2020,which continuously enhanced the capabilities of mobile broadband service based on Release 15 and realized the support for low-delay and high-reliability applications,such as Internet of Vehicles and industrial Internet.Currently,3GPP is working on Releases 17 and 18,focusing on meeting the demands of medium-and high-data-rate machine communication with low-cost and high-precision positioning,which will be published in June 2022.Thus,6G networks will further expand the application fields and scope of the Internet of Things to accommodate those services and applications that are beyond the capabilities of 5G networks.Herein,we present our vision,application scenarios,and key technological trends for 6G networks.Furthermore,we propose several future research opportunities in 6G networks with regard to industrialization and standardization. | Zhiqin WANG Ying DU Kejun WEI Kaifeng HAN Xiaoyan XU Guiming WEI Wen TONG Peiying ZHU Jianglei MA Jun WANG Guangjian WANG Xueqiang YAN Jiying XIANG He HUANG Ruyue LI Xinhui WANG Yingmin WANG Shaohui SUN Shiqiang SUO Qiubin GAO Xin SU | 2022 | Science China(Information Sciences)2022，65，5： | 17 |
| 5 | Advances in the treatment of traumatic scars with laser,intense pulsed light,radiofrequency,and ultrasound显示文摘Traumatic scarring is one of the most common complications after soft tissue injury caused by burns and trauma,which affects tens of millions of people worldwide every year.Traumatic scars diminish the quality of life due to disfigurement,symptoms of pain and itch,and restricted motion.The pathogenesis and pathophysiology of traumatic scar remain elusive.The management for traumatic scars is comprised of surgical and non-surgical interventions such as pressure therapy,silicone,corticosteroid,and radiotherapy,which are chosen by clinicians based on the physical examinations of scars.Recently,great progress in treating traumatic scars has been achieved by the development of novel technologies including laser,intense pulsed light(IPL),radiofrequency,and ultrasound.The aim of this review article was to summarize the advances of these technologies for traumatic scars intervention. | Xiujun Fu Jiying Dong Shen Wang Min Yan Min Yao | 2019 | Burns & Trauma2019，7，1： | 12 |
| 6 | LMM5.1 and LMM5.4,two eukaryotic translation elongation factor 1Alike gene family members,negatively affect cell death and disease resistance in rice显示文摘Lesion mimic mutant(LMM) genes, stimulating lesion formation in the absence of pathogens, play significant roles in immune response. In this study, we characterized a rice lesion mimic mutant, lmm5,which displayed light-dependent spontaneous lesions. Additionally, lmm5 plants exhibited enhanced resistance to all of the tested races of Magnaporthe oryzae and Xanthomonas oryzae pv. oryzae(Xoo) by increasing the expression of defense-related genes and the accumulation of hydrogen peroxide. Genetic analysis showed that the lesion mimic phenotype of lmm5 was controlled by two genes, lmm5.1 and lmm5.4, which were isolated with a map-based cloning strategy. Remarkably, LMM5.1 and LMM5.4 share a 97.4% amino acid sequence identity, and they each encode a eukaryotic translation elongation factor 1A(e EF1A)-like protein. Besides, LMM5.1 and LMM5.4 were expressed in a tissue-specific and an indicaspecific manner, respectively. In addition, high-throughput m RNA sequencing analysis confirmed that the basal immunity was constitutively activated in the lmm5 mutant. Taken together, these results suggest that the homologous e EF1A-like genes, LMM5.1 and LMM5.4, negatively affect cell death and disease resistance in rice. | Jiying Zhao Pengcheng Liu Chunrong Li Yanyan Wang Lequn Guo Guanghuai Jiang Wenxue Zhai | 2017 | Journal of Genetics and Genomics2017，44，2： | 10 |
| 7 | Cellulose conversion to polyols on supported Ru catalysts in aqueous basic solution显示文摘It is of great significance and challenge to achieve direct conversion of cellulose to specific polyols,e.g.,ethylene glycol and propylene glycol.For such selective conversion,a novel one-pot approach was studied by combination of alkaline hydrolysis and hydrogenation on supported Ru catalysts.A wide range of bases including solid bases,e.g.,Ca(OH)2 and La2O3,and phosphate buffers were examined in the cellulose reaction in water,and the cellulose conversions and polyol products depended largely on the basicity or pH values in the aqueous solutions.Ethylene glycol,1,2-propanediol,and especially 1,2,5-pentanetriol were obtained with selectivities of 15%,14% and 22%,respectively,at 38% cellulose conversion at pH 8 in phosphate buffer solution.These preliminary results provide potentials for efficient conversion of cellulose to targeted polyols by using the advantages of bases. | DENG TianYin,SUN JiYing & LIU HaiChao Beijing National Laboratory for Molecular Sciences,State Key Laboratory for Structural Chemistry of Stable and Unstable Species Green Chemistry Center,College of Chemistry and Molecular Engineering,Peking University,Beijing 100871,China | 2010 | Science China Chemistry2010，53，7： | 8 |
| 8 | Trajectory Estimation with Multi-range-rate System Based on Sparse Representation and Spline Model Optimization显示文摘The classic state methods for trajectory estimation in boost phase with multi-range-rate system include method of point-by-point manner and that of spline-model-based manner.Both are deficient in terms of model-approximation accuracy and systematic error determination thus resulting in the estimation errors well beyond the requirements,especially,concerning the maneuvering trajectory.This article proposes a new high-precision estimation approach based on the residual error analysis.The residual error comprises three components,i.e.systematic error,model truncation error and random error.The approach realizes self-adaptive estimation of systematic errors in measurements following the theory of sparse representation of signals to minimize the low-frequency components of residual errors.By taking median-and high-frequency components as indexes,the spline model-approximation is improved by optimizing node sequence of the spline function and the weight selection for data fusion through iteration.Simulation has validated the performances of the proposed method. | Liu Jiying,Zhu Jubo,Xie Meihua Department of Mathematics and Systems Science,National University of Defense Technology,Changsha 410073,China | 2010 | Chinese Journal of Aeronautics2010，23，1： | 5 |
| 9 | The normal cell proliferation and wound healing effect of polysaccharides from Ganoderma amboinense显示文摘To study the cell proliferation and wound healing activity of polysaccharides from Ganoderma amboinense(GAMPS),the polysaccharide was extracted by water extraction and alcohol precipitation method,and its monosaccharide composition and molecular weight were analyzed.The effects of different concentrations of GAMPS on the cell proliferation were determined by cell survival rate test,and the wound healing ability of GAMPS to NIH/3T3 cells was detected.The preliminary evaluation of the antioxidant ability of GAMPS was conducted by the oxygen radical absorbance capacity(ORAC).The results showed that the GAMPS was composed of glucose,mannose,and galactose at a molar ratio of 67.62:14.07:7.50,and the weightaverage molecular weights were 5.439×10^(6) and 1.704×10^(5) g/mol by using high-performance gel-permeation chromatography-multiple angle laser scatter(HPGPC-MALS)analysis.GAMPS(0.2μg/μL)showed the strongest proliferation ability to THP-1 cells,with cell survival rate of 178.7%.The wound healing effect of GAMPS(0.1μg/μL)was obvious on NIH/3T3 and 3.75μg/μL of GAMPS showed the strongest total antioxidant ability.All the results indicate that GAMPS promotes cell proliferation,and has cell wound healing effect and strong antioxidant activity.The results provide theoretical foundation for the development and utilization of GAMPS. | Shuangzhi Zhao Ming Lei Hui Xu Hailun He Alexander Suvorov Junhua Wang Jiying Qiu Qingxin Zhou Jinyu Yang Leilei Chen | 2021 | Food Science and Human Wellness2021，10，4： | 4 |
| 10 | Deformation mode-determined misorientation and microstructural characteristics in rolled pure Zr sheet显示文摘In this work, commercially pure Zr sheets were subjected to β air cooling and then rolled to different reductions(10% and 50%)at room temperature. Microstructures of both the β-air-cooled and the rolled specimens were well characterized by electron channelling contrast imaging and electron backscatter diffraction techniques, with special attentions paid to their misorientation characteristics. Results show that the β-air-cooled specimen owns a Widmanst?tten structure featured by lamellar grains with typical phase transformation misorientations. The 10% rolling allows prismatic slip and tensile twinning({11-21}<11-2-6> and{10-12}<10-11>) to be activated profusely, which produce new low-angle(~3°–5°) and high-angle(~35° and ~85°) misorientation peaks, respectively. After increasing the rolling reduction to 50%, twinning is suppressed and dislocation slip becomes the dominant deformation mode, with the lamellar grains highly elongated and aligned towards the rolling direction.Meanwhile, only one strong low-angle misorientation peak related to the prismatic slip is presented in the 50%-rolled specimen,with all other peaks disappeared. Analyses on local misorientations reveal that hardly any residual strains exist in the β-air-cooled specimen, which should be related to their sufficient relaxation during slow cooling. Residual strains introduced by 10% rolling are heterogeneously distributed near grain/twin boundaries while heavier deformation(50% rolling) produces much larger residual strains pervasively existing throughout the specimen microstructure. | CHAI LinJiang XIA JiYing ZHI Yan GOU YinNing CHEN LiangYu YANG ZhiNan GUO Ning | 2018 | Science China(Technological Sciences)2018，61，9： | 3 |
| 11 | Antigenicity of tissues and organs from GGTA1/CMAH/β4GalNT2 triple gene knockout pigs显示文摘Clinical xenotransplantations have been hampered by human preformed antibody-mediated damage of the xenografts.To overcome biological incompatibility between pigs and humans,one strategy is to remove the major antigens[Gal,Neu5 Gc,and Sd(a)]present on pig cells and tissues.Triple gene(GGTAI,CMAH,and β4 GalNT2)knockout(TKO)pigs were produced in our laboratory by CRISPR-Cas9 targeting.To investigate the antigenicity reduction in the TKO pigs,the expression levels of these three xenoantigens in the cornea,heart,liver,spleen,lung,kidney,and pancreas tissues were examined.The level of human IgG/IgM binding to those tissues was also investigated,with wildtype pig tissues as control.The results showed that aGal,Neu5 Gc,and Sd(a)were markedly positive in all the examined tissues in wildtype pigs but barely detected in TKO pigs.Compared to wildtype pigs,the liver,spleen,and pancreas of TKO pigs showed comparable levels of human IgG and IgM binding,whereas corneas,heart,lung,and kidney of TKO pigs exhibited significantly reduced human IgG and IgM binding.These results indicate that the antigenicity of TKO pig is significantly reduced and the remaining xenoantigens on porcine tissues can be eliminated via a gene targeting approach. | Ronggen Wang Miaomiao Ruan Runjie Zhang Lei Chen Xiaoxue Li Bin Fang Chu Li Xueyang Ren Jiying Liu Qiang Xiong Lining Zhang Yong Jin Lin Li Rongfeng Li Ying Wang Haiyuan Yang Yifan Dai | 2019 | The Journal of Biomedical Research2019，33，4： | 3 |
| 12 | Acetytation of ACAP4 regutates CCL18-elicited breast cancer cell migration and invasion显示文摘Tumor metastasis represents the main causes of cancer-related death.Our recent study showed that chemokine CCL18 secreted from tumor-associated macrophages regulates breast tumor metastasis,but the underlying mechanisms remain less clear.Here, we show that ARF6 GTPase-activating protein ACAP4 regulates CCL18-elicited breast cancer cell migration via the acetyltransferase PCAF-mediated acetylation.CCL18 stimulation elicited breast cancer cell migration and invasion via PCAF-dependent acetylation.ACAP4 physically interacts with PCAF and is a cognate substrate of PCAF during CCL18 stimulation.The acetylation site of ACAP4 by PCAF was mapped to Lys311 by mass spectrometric analyses.Importantly,dynamic acetylation of ACAP4 is essential for CCL18-induced breast cancer cell migration and invasion,as overexpression of the persistent acetylation-mimicking or nonacetylatable ACAP4 mutant blocked CCL18-elicited cell migration and invasion.Mechanistically,the acetylation of ACAP4 at Lys311 reduced the lipid-binding activity of ACAP4 to ensure a robust and dynamic cycling of ARF6-ACAP4 complex with plasma membrane in response to CCL18 stimulation.Thus,these results present a previously undefined mechanism by which CCL18-elicited acetylation of the PH domain controls dynamic interaction between ACAP4 and plasma membrane during breast cancer cell migration and invasion. | Xiaoyu Song Wei Liu Xiao Yuan Jiying Jiang Wanjuan Wang McKay Mullen Xuannv Zhao Yin Zhang Fusheng Liu Shihao Du Adeel Rehman Ruijun Tian Jian Li Andra Frost Zhenwei Song Hadiyah-Nicole Green Calmour Henry Xing Liu Xia Ding Dongmei Wang Xuebiao Yao | 2018 | Journal of Molecular Cell Biology2018，10，6： | 3 |
| 13 | Fossil bacteria in Xuanlong iron ore deposits of Hebei Province显示文摘Discovered in Early Proterozoic Xuanlong iron ore deposits are six genera of fossil iron bacteria, i. e. sphere (coenobium of) rod-shaped (monomer) Naumanniella, ellipsoid elliptical Ochrobium,sphere spherical Siderocapsa and chain spherical Siderococcus, chain rod-shaped Leptothrix and Lieskeella, and six genera of fossil blue bacteria, namely sphere spherical Gloeocapsa, Synechocystis and Globobacter, chain spherical Anabaena and Nostoc, and con-strictive septate tubular Nodularia. The biomineralized monomers and coenobia of the two cate-gories of bacteria, together with hematite plates made up the bacteria pelletal, bacteria silky, bacteria fibrous and clasty bacteria pelletal textural lamina. The bacteria pelletal laminae com-bined with other bacteria laminae to make up oncolite, stromatolite and laminate. The precipita-tion of iron oxide was accelerated due to iron and blue bacteria cohabiting on microbial film or mat. The Xuanlong iron ore deposits are microbial binding ore deposits of ocean source. | DAI Yongding, SONG Haiming & SHEN Jiying Institute of Geology and Geophysics, Chinese Academy of Sciences,Beijing 100029, China | 2004 | Science China Earth Sciences2004，47，4： | 3 |
| 14 | Effects of fermented protein feed on the growth performance of pond-raised crab显示文摘This study aimed to elucidate the effect of a pellet feed containing fermented proteins on pond-raised Chinese mitten crabs,Eriocheir sinensis in a 7-month crab feeding experiment in Gucheng Lake,Jiangsu province,China.The results showed that fermented protein could significantly increase mean weight gain,crab size and total yield compared with control group.Moreover,the mean weight of male crabs and the number of large-sized male crabs improved over those of the control group.However,feed efficiency ratio did not differ significantly between the two groups.The amino acid content in the muscles of the female crabs of both the groups was higher than that in the muscles of the male crabs.The present study suggests that fermented compound protein may be one kind of potential protein sources for E.sinensis. | Jiying Yu Jiayi Yu Xianming Chen Xin Zhou Yunxia Cai Huiyi Cai Peishi Yan | 2019 | Aquaculture and Fisheries2019，4，4： | 3 |
| 15 | Current advances of transition metal dichalcogenides in electromagnetic wave absorption:A brief review显示文摘Transition metal dichalcogenides(TMDs)show great advantages in electromagnetic wave(EMW)absorption due to their unique structure and electrical properties.Tremendous research works on TMD-based EMW absorbers have been conducted in the last three years,and the comprehensive and systematical summary is still a rarity.Therefore,it is of great significance to elaborate on the interaction among the morphologies,structures,phases,components,and EMW absorption performances of TMD-based absorbers.This review is devoted to analyzing TMD-based absorbers from the following perspectives:the EMW absorption regulation strategies of TMDs and the latest progress of TMD-based hybrids as EMW absorbers.The absorption mechanisms and component-performance dependency of these achievements are also summarized.Finally,a straightforward insight into industrial revolution upgrading in this promising field is proposed. | Shijie Zhang Jiying Li Xiaotian Jin Guanglei Wu | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，3： | 3 |
| 16 | Evolution Process of Urban Spatial Pattern in Hubei Province Based on DMSP/OLS Nighttime Light Data显示文摘This paper intends to investigate the urban spatial patterns of Hubei Province and its evolution from three different perspectives: urban nodes, urban connections and urban clusters. The research adopts nighttime light imagery of cities in Hubei Province, the viewpoint of ′point-axis-area′ in the ′point-axis system′ theory, and employs light index model, gravity model and social network analysis. The findings are as follows: 1) In terms of urban nodes, the urbanization process of Hubei has been carried out mainly on the basis of external expansion rather than internal increasing. The polarization trend of urban connection network is strengthening. 2) As for urban connections, the estimation of urban connections using light index model is capable of containing various actual flow, and the connections are getting increasingly closer. 3) In regard to urban groups, seven urban groups of varying sizes have formed. On that basis, three stable and relatively independent urban groups as the centers, namely Wuchang, Yichang and Xiangyang emerge as well. But the structures of ′Wuhan Metropolitan Area′, ′Yichang-Jingzhou-Jingmen City Group′ and ′Xiangyang-Shiyen-Suizhou City Group′, which are defined by local development strategy in Hubei Province, are different from the above three urban groups. | ZHENG Wensheng RUN Jiying ZHUO Rongrong JIANG Yupei WANG Xiaofang | 2016 | Chinese Geographical Science2016，26，3： | 3 |
| 17 | A Lectin from Chinese Mistletoe Increases γδ T Cell-mediated Cytotoxicity through Induction of Caspase-dependent Apoptosis显示文摘在这研究,槲寄生凝集素(ML ) 在 cytokine 网络的人的鲸鱼群妈三角洲 T 房间 cytotoxicity, apoptosis 和调整上从中国槲寄生和这 60 kDa 汉语 ML 的效果被净化被学习。 8 个 T 房间的细胞毒素的性质被使用 51Cr 版本测试评估并且采用了排序的激活荧光的房间和 enzyme-linkedimmunosorbent 试金分析确定房间 membranephospholipid 的 translocation , phosphatidylserine 和原子 DNA 破碎在 apoptosis.It 期间被发现那:(i) ML 有效地在剂量刺激了鲸鱼群妈三角洲 T 房间增长--并且时间依赖者举止;( i i ) ML 增加了鲸鱼群妈三角洲 T 房间 cytotoxicity ;( iii ) ML 能由增加以一种 支持inflammatory 方式调制 lipopolysaccharide-inducedcytokine 版本肿瘤坏死因素( TNF ) -alpharelease 并且禁止反煽动性的白介素( IL )的版本以caspase依赖、CD95独立的方式的-10;(iv) ML inducedapoptosis 。结果显示 ML 是到人的鲸鱼群妈三角洲 T 房间 cytotoxicity, apoptosis 和 cytokine 生产的 potentimmunomodulator。 | Fang GONG Yanhui MA Anlun MA Qiwen YU Jiying ZHANG Hong NIE Xuehua CHEN Baihua SHEN Ningli LI Dongqing ZHANG | 2007 | Acta Biochimica et Biophysica Sinica2007，39，6： | 2 |
| 18 | In situ enhanced bioremediation of dichlorvos by a phyllosphere Flavobacterium strain显示文摘A bacterium capable of degrading dichlorvos was isolated from the rape phyllosphere and designated YD4. The strain was identified as Flavobacterium sp., based on its phenotypic features and 16S rRNA gene sequence. Strain YD4 was able to utilize dichlorvos as the sole source of phosphorus. In situ enhanced bioremedia- tion of dichlorvos by YD4 was hereafter studied. Chlorpyrifos and phoxim could also be degraded by this strain as the sole phosphorus source. A higher degradation rate of dichlorvos was observed after spraying YD4 onto the surface of rape leaves when compared to the sterilized- YD4 and water-treated samples. The results indicated that pesticide-degrading epiphytic bacterium could become a new way for in situ phyllosphere bioremediation where the hostile niche is unsuitable for other pesticide-degrading bacteria isolated from soil and water. | Jiying NING Gang GANG Zhihui BAI Qing HU Hongyan QI Anzhou MA Xuliang ZHUAN Guoqiang ZHUANG | 2012 | Frontiers of Environmental Science & Engineering2012，6，2： | 2 |
| 19 | Downregulation of thioredoxin reductase 1 expression in the substantia nigra pars compacta of Parkinson's disease mice显示文摘Because neurons are susceptible to oxidative damage and thioredoxin reductase 1 is extensively distributed in the central nervous system and has antioxidant properties,we speculated that the enzyme may be involved in the pathogenesis of Parkinson’s disease.A Parkinson’s disease model was produced by intraperitoneal injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine into C57BL/6 mice.Real-time reverse transcription-PCR,western blot analysis and colorimetric assay showed that the levels of thioredoxin reductase 1 mRNA and protein were decreased,along with a significant reduction in thioredoxin reductase activity,in the midbrain of Parkinson’s disease mice compared with normal mice.Immunohistochemical staining revealed that the number of thioredoxin reductase 1-positive neurons in the substantia nigra pars compacta of Parkinson’s disease mice was significantly decreased compared with normal mice.These experimental findings suggest that the expression of thioredoxin reductase 1 in the substantia nigra pars compacta of Parkinson’s disease mice is significantly decreased,and that the enzyme may be associated with disease onset. | Zihua Liu Yuhong Jing Jie Yin Jiying Mu Tingting Yao Liping Gao | 2013 | Neural Regeneration Research2013，8，35： | 2 |
| 20 | Comparison of pH Value, TBA Value, Glycogen and Lactic Acid Content in Muscle of Landrace and Yorkshire under Different Storage Time and Conditions显示文摘In order to assess the meat quality under different storage time and conditions,the pH value,TBA value,glycogen and lactic acid content in muscle of Landrace and Yorkshire were measured. The results showed that within 10 h post slaughtering,post slaughtering time had extremely significant influence on pH value and lactic acid content of Landrace,but had no significant influence on glycogen content and TBA value. On the other hand,post slaughtering time had extremely significant influence on pH value of Yorkshire,but had no significant influence on glycogen,lactic acid content and TBA value. The pH values of Yorkshire at 3,5 and 10 h post slaughtering were 5. 21%( P < 0. 01),5. 64%( P < 0. 05) and 5. 59%( P < 0. 05) higher than those of Landrace,respectively; the lactic acid content in muscle of Landrace at 10 h post slaughtering was 56. 04%( P < 0. 05) higher than that of Yorkshire; the TBA value in muscle of Yorkshire at 10 h post slaughtering was 89. 19%( P < 0. 01) higher than that of Landrace; there was no significant difference in glycogen content between Yorkshire and Landrace. When pork stored at 4℃,storage time had no significant influence on pH value and glycogen content in muscle of Landrace,but had significant influence on drip loss,lactic acid content and TBA value; storage time had no significant influence on pH value,glycogen content and TBA value in muscle of Yorkshire,but extremely significant influence on drip loss and significant influence on lactic acid content. The pH value in muscle of Yorkshire at 24 h post storage at 4℃ was 6. 56%( P <0. 05) higher than that of Landrace; the glycogen contents in muscle of Landrace at 24,48,72,96,120 and 144 h post storage at 4℃ were 84. 90%( P <0. 05),78. 40%( P <0. 01),101. 87%( P <0. 05),83. 80%( P < 0. 05),83. 59%( P < 0. 05) and 67. 25%( P < 0. 01) higher than those of Yorkshire,respectively; the drip loss of Landrace at 72 h post storage and TBA value at 144 h post storage were 55. 70%( P < 0. 05) and 141. 33%( P < 0. 01) higher than those of Yorkshire,respectively; there was no significant difference in glycogen content between Yorkshire and Landrace. When pork stored at -20℃,storage time had significant influence on TBA value in muscle of Landrace,but had no significant influence on pH value,thawing water loss rate,glycogen and lactic acid content; storage time had no significant impact on pH value,thawing water loss rate,glycogen content and TBA value in muscle of Yorkshire,and had significant influence on lactic acid content. The pH value in muscle of Yorkshire at 24 h post storage at -20℃ was 5. 43%( P < 0. 05) higher than that of Landrace; the glycogen contents in muscle of Landrace at 24,48,72,96,120 h post storage at -20℃ were 85. 08%( P < 0. 05),108. 66%( P < 0. 01),72. 69%( P < 0. 05),90. 31%( P < 0. 01),70. 38%( P > 0. 05) higher than those of Yorkshire,respectively; the thawing water loss rates of Landrace at 24 and 72 h were 160. 14%( P <0. 05) and 74. 32%( P <0. 05) higher than those of Yorkshire,respectively; there was no significant difference in lactic acid content and TBA value at the same time point between Yorkshire and Landrace. | Zhang Yin Guo Jianfeng Lin Haichao Wang Jiying Wang Cheng Wu Ying | 2017 | Animal Husbandry and Feed Science2017，9，3： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员