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| 1 | 人工湿地系统对污水磷的净化效果显示文摘建立以亚热带湿生、水生植物为主的十二套下行流—上行流人工湿地系统作为处理城镇生活污水的对策。以其中四套研究其在不同的水力负荷及气候条件下对污水中磷的去除效果。人工湿地系统随处理运行时间的推移趋于稳定 ,对污水中的总磷、无机磷显示较好的净化效率 ,平均去除率在冬季达到 40 %以上 ,夏季达到 60 %以上 ,出水达到国家地面水Ⅲ级标准。水生植物在系统中起到明显作用 ,有植物系统的除磷效率及稳定性均高于无植物对照 ,其中 2号茭白—石菖蒲系统的效果最好 ,总磷平均去除率为 65%。 4号草—苔草系统在高水力负荷下的净化效果优于 2号。 | WU Zhen-bin CHEN Hui-rong HE Feng CHENG Shui-ping FU Gui-ping JIN Jian-ming QIU Dong-ru REN Ming-xun 任明迅 金建明 贺锋 陈辉蓉 付贵萍 吴振斌 邱东茹 成水平 | 2001 | 水生生物学报2001，25，1： | 188 |
| 2 | The Chinese Society of Clinical Oncology(CSCO):Clinical guidelines for the diagnosis and treatment of gastric cancer,2021显示文摘There exist differences in the epidemiological characteristics,clinicopathological features,tumor biological characteristics,treatment patterns,and drug selections between gastric cancer patients from the Eastern and Western countries.The Chinese Society of Clinical Oncology(CSCO)has organized a panel of senior experts specializing in all sub-specialties of gastric cancer to compile a clinical guideline for the diagnosis and treatment of gastric cancer since 2016 and renews it annually.Taking into account regional differences,giving full consideration to the accessibility of diagnosis and treatment resources,these experts have conducted expert consensus judgment on relevant evidence and made various grades of recommendations for the clinical diagnosis and treatment of gastric cancer to reflect the value of cancer treatment and meeting health economic indexes in China.The 2021 CSCO Clinical Practice Guidelines for Gastric Cancer covers the diagnosis,treatment,follow-up,and screening of gastric cancer.Based on the 2020 version of the CSCO Chinese Gastric Cancer guidelines,this updated guideline integrates the results ofmajor clinical studies from China and overseas for the past year,focused on the inclusion of research data from the Chinese population for more personalized and clinically relevant recommendations.For the comprehensive treatment of non-metastatic gastric cancer,attentions were paid to neoadjuvant treatment.The value of perioperative chemotherapy is gradually becoming clearer and its recommendation level has been updated.For the comprehensive treatment of metastatic gastric cancer,recommendations for immunotherapy were included,and immune checkpoint inhibitors fromthird-line to the first-line of treatment for different patient groups with detailed notes are provided. | Feng-Hua Wang Xiao-Tian Zhang Yuan-Fang Li Lei Tang Xiu-Juan Qu Jie-Er Ying Jun Zhang Ling-Yu Sun Rong-Bo Lin Hong Qiu Chang Wang Miao-Zhen Qiu Mu-Yan Cai QiWu Hao Liu Wen-Long Guan Ai-Ping Zhou Yu-Jing Zhang Tian-Shu Liu Feng Bi Xiang-Lin Yuan Sheng-Xiang Rao Yan Xin Wei-Qi Sheng Hui-Mian Xu Guo-Xin Li Jia-Fu Ji Zhi-Wei Zhou Han Liang Yan-Qiao Zhang Jing Jin Lin Shen Jin Li Rui-Hua Xu | 2021 | Cancer Communications2021，41，8： | 97 |
| 3 | Coking wastewater treatment for industrial reuse purpose: Combining biological processes with ultrafiltration, nanofiltration and reverse osmosis显示文摘A full-scale plant using anaerobic, anoxic and oxic processes (A1/A2/O), along with a pilot-scale membrane bioreactor (MBR), nanofiltration (NF) and reverse osmosis (RO) integrated system developed by Shanghai Baosteel Chemical Co. Ltd., was investigated to treat coking wastewater for industrial reuse over a period of one year. The removals reached 82.5% (COD), 89.6% (BOD), 99.8% (ammonium nitrogen), 99.9% (phenol), 44.6% (total cyanide (T-CN)), 99.7% (thiocyanide (SCN-)) and 8.9% (fluoride), during the A1/A2/O biological treatment stage, and all parameters were further reduced by over 96.0%, except for fluoride (86.4%), in the final discharge effluent from the currently operating plant. The pilot-scale MBR process reduced the turbidity to less than 0.65 NTU, and most of the toxic organic compounds were degraded or intercepted by the A1/A2/O followed MBR processes. In addition, parameters including COD, T-CN, total nitrogen, fluoride, chloride ion, hardness and conductivity were significantly reduced by the NF-RO system to a level suitable for industrial reuse, with a total water production ratio of 70.7%. However, the concentrates from the NF and RO units were highly polluted and should be disposed of properly or further treated before being discharged. | Xuewen Jin Enchao Li Shuguang Lu Zhaofu Qiu Qian Sui | 2013 | Journal of Environmental Sciences2013，25，8： | 38 |
| 4 | Impact of different clinical pathways on outcomes of patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: the RAPID-AMI study显示文摘背景当前的指南作为选择的第一治疗支持主要经皮的冠的干预(主要一种总线标准)( 与 thrombolytic 治疗对比) 为有尖锐圣片断举起的病人心肌的梗塞(STEMI ) 特别当在 12 小时症状发作以内交付了时。我们试图从 2005 年 11 月与 STEMI.Methods 在病人在结果在灌注延期和随后的改进的减小上评估不同临床的小径的影响到 2007 年 11 月,有明确的 STEMI 的 546 个连续病人,在在紧急情况房间的到达之上是 triaged 经历主要一种总线标准,被包括。他们, 271 个病人直接被带到 catheterization 实验室(快速的组) ,并且 275 个病人首先进入冠的照顾单位(CCU ) 或心脏的病房,然后转了到 catheterization 实验室(非快速的组) 。主要端点是 door-to-balloon ( D28 )时间,并且第二等的端点包括了山峰 CK-MB 水平和主要心脏的不利事件(向)的率在住院期间并且在30天的临床的 follow-up.Results 基线临床的特征包括死亡,梗塞,或目标容器 revascularization 估计的梗塞尺寸, angiographic 特征和程序的成功率在二个组之间是可比较的,除了更多的病人以前收到了 glycoprotein b/a 受体禁止者之外一D2B 时间被弄短((108 ? ㈨ ? 洠污 ???? 畯 ? 晡整 ? 桴 ? 灯牥瑡潩 ? 慷 ? 楳湧晩捩湡汴 ? 楨桧牥琠慨 ? 桴瑡漠 ? 桴 ? 湫 ' 覞煬潠 P 潲灵吗?? | ZHANG Qi ZHANG Rui-yan QIU Jian-ping JIN Hui-gen ZHANG Jun-feng WANG Xiao-long JIANG Li LIAO Min-lei HU Jian DING Feng-hua ZHANG Jian-sheng SHEN Wei-feng | 2009 | Chinese Medical Journal2009，，6： | 32 |
| 5 | Development of a Chinese land data assimilation system:its progress and prospects显示文摘陆地数据吸收的目的是为改进陆地表面状态的评价把多来源观察合成陆地表面模型的动力学。我们为中国的陆地领土开发了一个陆地数据吸收系统。在这个系统,普通陆地模型和简单生物圈,模型 2 被用来模仿陆地表面过程。当转移的观察操作员为预言建模进估计的亮度温度,融化并且结冰的土壤,雪,湖,和植被的放射的转移模型被使用。一个 Monte-Carlo 顺序的过滤器,整体 Kalman 过滤器,作为数据吸收方法被实现集成当模特儿并且观察。系统能够遥远地吸收被动微波察觉到的数据象特殊传感器微波成像器那样(SSM 我) , TRMM 微波成像器(TMI ) ,和先进微波扫描辐射计为曙光女神(AMSRE ) 提高了并且在土壤和雪的 situmeasurements 常规。与 0.25 度的一个空间决定和一个小时的时间的分辨率,为土壤潮湿,土壤温度,雪和冻结的土壤的空间与时间地一致的吸收数据集被生产了。这篇论文介绍在数据吸收算法,陆地表面水文学变量的陆地表面建模微波遥感,和大气的强迫的数据的准备上做的中国陆地数据吸收系统和进步的开发。为未来开发开发陆地数据吸收系统和观点的不同特征和挑战也被讨论。 | Li Xin Huang Chunlin Che Tao Jin Rui Wang Shugong Wang Jiemin Gao Feng Zhang Shuwen Qiu Chongjian Wang Chenghai | 2007 | Progress in Natural Science:Materials International2007，17，8： | 30 |
| 6 | Randomized comparison of intracoronary tirofiban versus urokinase as an adjunct to primary percutaneous coronary intervention in patients with acute ST-elevation myocardial infarction: results of the ICTUS-AMI trial显示文摘 | ZHU Tian-qi ZHANG Qi DING Feng-hua QIU Jian-ping JIN Hui-geng JIANG Li LU Lin ZHANG Rui-yan HU Jian YANG Zhen-kun SHEN Ying SHEN Wei-feng | 2013 | Chinese Medical Journal2013，，16： | 27 |
| 7 | Evaluation of soil fertility of the shelter-forest land along the Tarim Desert Highway显示文摘To study the changes of soil fertility of the shelter-forest land along the Tarim Desert Highway, soils from the forest land were collected at the layers of 0―10 cm, 10―20 cm, 20―30 cm. Different soil fertility parameters were measured, and quantitative evaluation of soil fertility was performed by the soil integrated fertility index (IFI). The main results show that the construction of the shelter forest along the Tarim Desert Highway improved the soil physical structure, increased soil porosity and enhanced wa- ter-holding capacity. With the increase of plantation time of the shelter forest, soil microbial biomass C, N, P and the activities of six types of enzyme were enhanced, which promoted the accumulation and transformation of soil nutrients of the forest land. Consequently, the soil nutrients in 12-year-old forest land were much higher than in the newer ones and drifting sand. However, soil salt content of the older forest land was higher owing to the drip-irrigation with salt water. Through the comprehensive evalua- tion, we found that soil fertility index in the forest land was enhanced with the forest age, and it had close correlations with the growth indices of the forest trees. In summary, construction of the shelterforest along the Tarim Desert Highway accelerated the improvement of aeolian soil in the forest land, and the soil fertility improved year by year. We conclude that the forest trees grow normally under the stress of the present drip-irrigation with salt water. | JIN ZhengZhong LEI JiaQiang XU XinWen LI ShengYu ZHAO SiFeng QIU YongZhi XU Bo | 2008 | Chinese Science Bulletin2008，53，S2： | 18 |
| 8 | An HNF 1α-regulated feedback circuit modulates hepatic fibrogenesis via the crosstalk between hepatocytes and hepatic stellate cells显示文摘 | Hui Qian Xing Deng Zhao-Wei Huang Ji Wei Chen-Hong Ding Ren-Xin Feng Xin Zeng Yue-Xiang Chen Jin Ding Lei Qiu Zhen-Lin Hu Xin Zhang Hong-Yang Wang Jun-Ping Zhang Wei-Fen Xie | 2015 | Cell Research2015，25，8： | 15 |
| 9 | Human placenta-derived mesenchymal stem cells loaded on linear ordered collagen scaffold improves functional recovery after completely transected spinal cord injury in canine显示文摘Traumatic spinal cord injury(SCI) is a major challenge in the clinic. In this study, we sought to examine the synergistic effects of linear ordered collagen scaffold(LOCS) and human placenta-derived mesenchymal stem cells(hPMSCs) when transplanted into completely transected beagle dogs. After 36 weeks observation, we found that LOCS+hPMSCs implants promoted better hindlimb locomotor recovery than was observed in the non-treatment(control) group and LOCS group. Histological analysis showed that the regenerated tissue after treatment was well integrated with the host tissue, and dramatically reduced the volume of cystic and chondroitin sulfate proteoglycans(CSPGs) expression. Furthermore, the LOCS+hPMSCs group also showed more neuron-specific βIII-tubulin(Tuj-1)-and NeuN-positive neurons in the lesion area, as well as axonal regeneration, remyelination and synapse formation in the lesion site. Additionally, dogs in the LOCS+hPMSCs group experienced enhanced sprouting of both ascending(CGRP-positive) sensory fibers and descending(5-HT-and TH-positive) motor fibers at the lesion area. All these data together suggested that the combined treatment had beneficial effects on neuronal regeneration and functional improvement in a canine complete transection model. Therefore, LOCS+hPMSCs implantation holds a great promise for bridging the nerve defect and may be clinically useful in the near future. | Sufang Han Zhifeng Xiao Xing Li Huan Zhao Bin Wang Zhixue Qiu Zhi Li Xin Mei Bai Xu Caixia Fan Bing Chen Jin Han Yanzheng Gu Huilin Yang Qin Shi Jianwu Dai | 2018 | Science China(Life Sciences)2018，61，1： | 15 |
| 10 | Comprehensive eco-environmental effects of the shelter-forest ecological engineering along the Tarim Desert Highway显示文摘In this work, we report a comprehensive study about the eco-environmental effects of the shelter forest along the Tarim Desert Highway, including the effects on aeolian environment, soil, micro-climate, biodiversity, and groundwater. The results show that: (1) The movement of windblown sand near the ground surface was affected by the shelter forest. The wind speed and sediment transport rate in the shelter forest decreased by 64%―80% and 87.45%―99.02%, respectively. In addition, there were also significant changes in the sand flux structure, the sand grain size, and the deflation and deposition on the ground surface. (2) Compared to the natural mobile sand, the soil bulk density in the forest area decreased while the total salt content, the total porosity, and the water content increased. In addition, the soil fertility was significantly improved in the forest area, and showed the 'first rapid, then slow' variation pattern. (3) The shelter forest showed positive effects on the micro-climate. Within the 6 m height above the ground, the air temperature in the shelter forest at different heights was lower than that in the mobile sand, while the air humidity was higher, while, the soil temperature was also lower in the shelter forest than mobile sand. (4) The number of soil microbial species increased significantly with the improvement of habitat in the shelterbelt. However, the population of different species was not distributed evenly across the surveyed area. (5) Currently, no significant effects of groundwater-pumping and forest-irrigation water have been found on the groundwater level and its salinity. The variation amplitude of both groundwater level and salinity was at the level of centimeters and 1g/L, respectively. No obvious variation trend has been observed. | LEI JiaQiang LI ShengYu JIN ZhengZhong FAN JingLong WANG HaiFeng FAN DongDong ZHOU HongWei GU Feng QIU YongZhi XU Bo | 2008 | Chinese Science Bulletin2008，53，S2： | 14 |
| 11 | Clinical Manifestations of Fibrosing Mediastinitis in Chinese Patients显示文摘 | Yan Hu Jian-Xing Qiu Ji-Ping Liao Hong Zhang Zhe Jin Guang-Fa Wang | 2016 | Chinese Medical Journal2016，，22： | 14 |
| 12 | Gene expression profiling reveals Ki-67 associated proliferation signature in human glioblastoma显示文摘背景永久细胞的增长在 gliomagenesis 期间是基本特征, Ki-67 是在人的 glioblastoma multiforme ( GBM )的古典增长标记之一 .However ,为在 GBM 的细胞的增长的驱动程序基因或核心小径一直不是我们由 immunohistochemistry 评估了的阐明的 systematically.Methods 在有 GBM 和 64 件 GBM 样品的一个总数的 156 个中国病人的临床的结果的 Ki-67 表示的预示的值为进一步的 Agilent | JIN Qiang ZHANG Wei QIU Xiao-guang YAN Wei YOU Gan LIU Yan-wei JIANG Tao WANG Lei | 2011 | Chinese Medical Journal2011，，17： | 12 |
| 13 | Absence of gender disparity in short-term clinical outcomes in patients with acute ST-segment elevation myocardial infarction undergoing irolimus-eluting stent based primary coronary intervention: a report from Shanghai Acute Coronary Event (SACE) Registry显示文摘背景使随机化的、控制试用表明了 sirolimus-eluting stent (SES ) 的优势培植在主要经皮的冠的干预(一种总线标准) 期间与赤裸金属的 stents 对比,在有圣举起心肌的梗塞(STEMI ) 的病人。这研究试图测试 SES 治疗的临床的好处独立于在这 setting.Methods 的性的假设有经历基于 SES 的主要一种总线标准的 STEMI 的 2042 个病人的一个总数有希望地被注册进上海尖锐冠的事件(SACE ) 登记(1574 个男人和 468 个女人) 。基线人口分布, angiographic 和一种总线标准特征,和在里面医院和 30 天的主要不利心脏的事件(向) 作为性的功能被分析。与男人相比结果,女人们是更旧、更经常有的高血压,糖尿病,和血胆脂醇过多。血小板 glycoprotein IIb/IIIa 受体禁止者的使用(GPI, 65.5% 对 62.2% , P=0.10 ) 并且程序的成功率(95.0% 对 94.2% , P=0.52 ) 在两性是类似的。在里面医院死亡和向发生了在 3.8% 和 7.6% ,和 4.5% 和 8.1% 在男、女的病人,分别地(所有 P > 0.05 ) 。在 30 天的后续,幸存(94.3% 对 93.8% , P=0.66 ) 并且没有向的幸存(90.2% 对 89.3% , P=0.52 ) 显著地没在男人和女人之间不同。在为在耐心的人口分布, angiographic 和 proceduralfeatures 的差别的调整以后,在任何一个在里面医院没有重要差别( OR=0.77 , 0.48~1.22 的95%C/, P=0.30 )或30天的死亡( OR=1.28 , 0.73~2.23 的95%C/, P=0.38 )在尽管有更先进的年龄的女人和 men.Conclusion 之间并且在女人风险因素聚类,有 基于SES 的主要一种总线标准对待的 STEMI 的女病人作为他们的男对应物有类似的在里面医院和短期的临床的结果。 | ZHANG Qi QIU Jian-ping ZHANG Rui-yan LI Yi-gang HE Ben JIN Hui-gen ZHANG Jun-feng WANG Xiao-long JIANG Li LIAO Min-lei HU Jian SHEN Wei-feng | 2010 | Chinese Medical Journal2010，，7： | 10 |
| 14 | Fixation of CO_2 by electrocatalytic reduction to synthesis of dimethyl carbonate in ionic liquid using effective silver-coated nanoporous copper composites显示文摘与高表面区域,开的孔和高效率,催化剂在 electrocatalytic 被准备并且第一采用了 CO2 的减小和 dimethyl 碳酸盐(直接数字控制) 的 electrosynthesis。为在离子的液体的 CO2 的 electrocatalytic 减小的电气化学的性质被周期的 voltammogram (CV ) 学习。象 electrocatalytic 性能上的温度,工作潜力和阴极材料一样的各种各样的反应变量的效果也被调查。直接数字控制的 80% 产量在最佳的反应条件下面被获得。 | Xuan Yun Wang Su Qin Liu Ke Long Huang Qiu Ju Feng De Lai Ye Bing Liu Jin Long Liu Guan Hua Jin | 2010 | Chinese Chemical Letters2010，21，8： | 10 |
| 15 | Outcomes of CAG Regimen for Refractory Biphenotypic Acute Leukemia Patients显示文摘Objective To evaluated the efficiency of low-dose cytosine arabinoside plus aclarubicin with concurrent administration of granulocyte colony-stimulating factor (CAG) regimen for refractory biphenotypic acute leukemia (BAL). Methods We treated 5 refractory BAL patients by CAG regimen (10 mg·m-2 cytosine arabinoside subcutaneously administrated every 12 hours, day 1-14; 5-7 mg·m-2 aclarubicin intravenously administrated daily, day 1-8; and concurrently used 200μg·m-2·d-1 granulocyte colony-stimulating factor subcutaneously) from November 2002 to April 2007. The efficacy of the regimen was evaluated by response rate, and the side effects were also measured. Results The complete remission rate was 80%, median duration of absolute neutrophil count< 5.0×108/L and platelet count<2.0×1010/L was day 13 and day 1, respectively; and the infection rate was low (Ⅲ-Ⅳ infection rate, 20.00%). Conclusion CAG regimen as remission induction chemotherapy for BAL patients is effective with a high remission rate and low toxicity. | Guang-sheng He Xiang Zhang De-pei Wu Ai-ning Sun Zheng-ming Jin Hui-ying Qiu Miao Miao Xiao-wen Tang Zheng-zheng Fu Yue Han | 2009 | Chinese Medical Sciences Journal2009，24，3： | 10 |
| 16 | An Innovative Process for Direct Reduction of Cold bound Pellets from Iron Concentrate with a Coal-based Rotary Kiln显示文摘Successfully developed an innovative process of direct reduction of cold bound pellets from iron ore concentrate with a coal based rotary kiln, in comparison with the traditional direct reduction of fired oxide pellets in coal based rotary kilns , possesses such advantages as: shorter flowsheet, lower capital investment, greater economic profit, good quality of direct reduced iron. The key technologies , such as the composite binder and corresponding feasible techniques were employed in practice. A mill utilizing this process and with an annual capacity of 50 thousand ton DRI has been put into operation. | ZHU De qing QIU Guan zhou JIANG Tao XU Jin chang | 2000 | Journal of Central South University2000，12，2： | 10 |
| 17 | Incremental value of contrast echocardiography in the diagnosis of left ventricular noncompaction显示文摘 | Xiaoxiao Zhang Li Yuan Linli Qiu Yali Yang Qing Lv Lin Li Jing Wang Lin He Li Zhang Xinfang Wang Mingxing Xie Xu Yu Jin | 2016 | Frontiers of Medicine2016，10，4： | 10 |
| 18 | Impact of Climate and Land-Use Changes on Water Security for Agriculture in Northern China显示文摘North China is the most important food basket of China, where the majority of wheat and corn are produced. Most crops grown in North China are irrigated, thus water security is food security. Since the 1980s, drying has been frequently observed, as shown by a reduction in precipitation, cutoff in riverflow, and shrinkage of lakes. This increase in drying cannot be explained by climate change alone. We propose that intensive land-use in this area in recent decades has had a significant impact. The objectives of the study are to develop a quantitative model of the concurrent processes of climate change and land-use in North China, and to estimate the relative contributions of each on the observed drying. We integrated relevant socioeconomic data, land-use data, and climate data in the model, and carried out a detailed multi-temporal (decade, year, day) analysis. Results showed that land-use has greatly changed since 1999. This change is mainly associated with an extremely important 1999 national policy of 'returning farmland and grazing land to forest and grassland'. We found an interesting interaction between climate change and land use policy on riverflow, runoff, and evapotranspiration. During 1970s and 1980s, climate change explained more than 80%, while the land-use change explained only 10% of the riverflow change. The relative contributions were 45 and 45% in the 1980s-1990s and 35 and 55% in the 1990s-2000s respectively for climate change and land-use change. Since the 1990s land-use change has also contributed more to runoff change than climate change. The opposite trend was found for changes in evapotranspiration. Water availability for agriculture in northern China is simultaneously stressed by extensive changes in land-use and rapid climate change. Adaptation of ecological principles, such as the 'returning farmland/grazing land to forest and grassland' policy, and other adjustments of economic developmental strategies can be effective tools to mitigate the water shortage problem in northern China and promote sustainable agricultural and food development. | QIU Guo-yu YIN Jin Shu Geng | 2012 | Journal of Integrative Agriculture2012，11，1： | 10 |
| 19 | Efficacy and Safety of Teriflunomide in Chinese Patients with Relapsing Forms of Multiple Sclerosis: A Subgroup Analysis of the Phase 3 TOWER Study显示文摘Background:Disease-modifying therapy is the standard treatment for patients with multiple sclerosis (MS)in remission.The primary objective of the current analysis was to assess the efficacy and safety of two teriflunomide doses (7mg and 14mg)in the subgroup of Chinese patients with relapsing MS included in the TOWER study. Methods:TOWER was a multicenter,multinational,randomized, double-blind,parallel-group (three groups),placebo-controlled study.This subgroup analysis includes 148 Chinese patients randomized to receive either teriflunomide 7mg (n =51), teriflunomide 14mg (n=43),or placebo (n=54). Results:Of the 148patients in the intent-to-treat population, adjusted annualized-relapse rates were 0.63(95% confidence interval [CI]:0.44,0.92)in the placebo group,0.48(95%CI:0.33, 0.70)in the teriflunomide 7mg group,and 0.18(95%CI:0.09,0.36)in the terifltmomide 14mg group;this corresponded to a significant relative risk reduction in the teriflunomide 14mg group versus placebo (-71.2%,P =0.0012).Terifiunomide 14mg also tended to reduce 12-week confirmed disability worsening by 68.1% compared with placebo (hazard ratio:0.319,P =0.1194).There were no differences across all treatment groups in the proportion of patients with treatment-emergent adverse events (TEAEs;72.2% in the placebo group,74.5%in the teriflunomide 7mg group,and 69.8% in the teriflunomide 14mg group);corresponding proportions for serious adverse events were 11.1%,3.9%,and 11.6%,respectively.The most frequently reported TEAEs with teriflunomide versus placebo were neutropenia,increased alanine aminotransferase,and hair thinning. Conclusions:Teriflunomide was as effective and safe in the Chinese subpopulation as it was in the overall population of patients in the TOWER trial.Teriflunomide has the potential to meet unmet medical needs for MS patients in China. | Wei Qiu De-Hui Huang Shi-Fang Hou Mei-Ni Zhang Tao Jin Hui-Qing Dong Hua Peng Chao-Dong Zhang Gang Zhao Yi-Ning Huang Dong Zhou Wei-Ping Wu Bao-Jun Wang Ji-Mei Li Xing-Hu Zhang Yan Cheng Hai-Feng Li Ling Li Chuan-Zhen Lu Xu Zhang Bi-Tao Bu Wan-Li Dong Dong-Sheng Fan Xue-Qiang Hu Xian-Hao Xu | 2018 | Chinese Medical Journal2018，，23： | 10 |
| 20 | WEAKLY SWIRLING TURBULENT FLOW IN TURBID WATER HYDRAULIC SEPARATION DEVICE显示文摘This article deals with the characteristics of weakly swirling turbulent flow field in a Turbid Water Hydraulic Separation Device(TWHSD) through experimental and numerical researches.The flow field was measured by PIV,which provided streamlines,vortex structure,vorticity and velocity distribution in different test planes in the TWHSD.On the basis of the experimental results,the tangential and radial velocity distributions of the swirling flow field were obtained.Meanwhile,the numerical simulations were conducted with the RNG k-ε and RSM turbulence models,respectively.According to the experimental and numerical results,the characteristics of the clear water flow field inside the TWHSD were determined.In view of simulation accuracy and time consumption,it is suggested to apply the RNG k-ε model instead of the RSM model,which is more time consuming,to make further study on two-phases flow fields in the device. | LI Lin QIU Xiu-yun JIN Sheng XIAO Jun GONG Shou-yuan | 2008 | Journal of Hydrodynamics2008，20，3： | 9 |
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