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| 1 | Molecular basis for the selective and ABA-independent inhibition of PP2CA by PYL13显示文摘PYR1/PYL/RCAR 家庭蛋白质(PYL ) 是描绘得好的 abscisic 酸(骆驼毛的织物) 受体。在在 Arabidopsis thaliana 的 14 个 PYL 成员之中, PYL13 是无反应的骆驼毛的织物,它的功能留下了逃犯。这里,我们证明 PYL13 有选择地禁止独立于骆驼毛的织物的 PP2CA 的磷酸酶活动。PYL13-PP2CA 建筑群的水晶结构,它在 2.4 Å 坚定;分辨率,阐明在 PP2CA 和 PYL13 之间的特定的识别的分子的基础。除了在 PYL 和 PP2Cs 之间的正规相互作用,一个额外的接口被识别在附近包含一个元素一以前在 PP2CA 的 uncharacterized CCCH 锌手指(ZF ) 主题。顺序强风识别了另一 56 包含 ZF PP2Cs,所有哪个从植物。结构也为 PYL13 的 ABA 无反应揭示分子的决定因素。最后,生物化学的分析建议那 PYL13 可以有 PYL10 的 hetero-oligomerize。这二 PYL 在他们 PP2Cs 的各自的骆驼毛的织物无关的抑制反对对方。生物化学、结构的研究在植物的压力反应提供重要卓见进 PYL13 的函数并且为 PYL13 的未来 biotechnological 应用程序安装一个基础。 | WenqiLi #x0002A LiWang #x0002A XinleiSheng #x0002A ChuangyeYan RuiZhou JingHang PingYin NiengYan | 2013 | Cell Research2013，，12： | 10 |
| 2 | Screening melamine adulterant in milk powder with laser Raman spectrometry显示文摘 | Yan Cheng Yiyang Dong Jinghang Wu Xiaoran Yang Hua Bai Hongyan Zheng Dongmei Ren Yundong Zou Ming Li | 2009 | Journal of Food Composition and Analysis2009，，2： | 2 |
| 3 | Screening melamine adulterant in milk powder with laser Raman spectrometry显示文摘 | Yan Cheng Yiyang Dong Jinghang Wu Xiaoran Yang Hua Bai Hongyan Zheng Dongmei Ren Yundong Zou Ming Li | 2009 | Journal of Food Composition and Analysis2009，，2： | 1 |
| 4 | Screening melamine adulterant in milk powder with laser Raman spectrometry显示文摘 | CHENG Yang DONG Yiyang WU Jinghang | | 0，，02： | 1 |
| 5 | Research on Tree Kernel-Based Personal Relation Extraction显示文摘 | Peng Cheng Gu Jinghang Qian Longhua | 2012 | Communications in Computer and Information Science2012，333，： | 1 |
| 6 | Population spatialization with pixel-level attribute grading by considering scale mismatch issue in regression modeling显示文摘Population spatialization is widely used for spatially downscaling census population data to finer-scale.The core idea of modern population spatialization is to establish the association between ancillary data and population at the administrative-unit-level(AUlevel)and transfer it to generate the gridded population.However,the statistical characteristic of attributes at the pixel-level differs from that at the AU-level,thus leading to prediction bias via the cross-scale modeling(i.e.scale mismatch problem).In addition,integrating multi-source data simply as covariates may underutilize spatial semantics,and lead to incorrect population disaggregation;while neglecting the spatial autocorrelation of population generates excessively heterogeneous population distribution that contradicts to real-world situation.To address the scale mismatch in downscaling,this paper proposes a Cross-Scale Feature Construction(CSFC)method.More specifically,by grading pixel-level attributes,we construct the feature vector of pixel grade proportions to narrow the scale differences in feature representation between AU-level and pixel-level.Meanwhile,fine-grained building patch and mobile positioning data are utilized to adjust the population weighting layer generated from POI-density-based regression modeling.Spatial filtering is furtherly adopted to model the spatial autocorrelation effect of population and reduce the heterogeneity in population caused by pixel-level attribute discretization.Through the comparison with traditional feature construction method and the ablation experiments,the results demonstrate significant accuracy improvements in population spatialization and verify the effectiveness of weight correction steps.Furthermore,accuracy comparisons with WorldPop and GPW datasets quantitatively illustrate the advantages of the proposed method in fine-scale population spatialization. | Yuao Mei Zhipeng Gui Jinghang Wu Dehua Peng Rui Li Huayi Wu Zhengyang Wei | 2022 | Geo-Spatial Information Science2022，25，3： | 1 |
| 7 | Motion Planning for a Cable-Driven Lower Limb Rehabilitation Robot with Movable Distal Anchor Points显示文摘This article introduces a cable-driven lower limb rehabilitation robot with movable distal anchor points(M-CDLR).The traditional cable-driven parallel robots(CDPRs)control the moving platform by changing the length of cables,M-CDLR can also adjust the position of the distal anchor point when the moving platform moves.The M-CDLR this article proposed has gait and single-leg training modes,which correspond to the plane and space motion of the moving platform,respectively.After introducing the system structure configuration,the generalized kinematics and dynamics of M-CDLR are established.The fully constrained CDPRs can provide more stable rehabilitation training than the under-constrained one but requires more cables.Therefore,a motion planning method for the movable distal anchor point of M-CDLR is proposed to realize the theoretically fully constrained with fewer cables.Then the expected trajectory of the moving platform is obtained from the motion capture experiment,and the motion planning of M-CDLR under two training modes is simulated.The simulation results verify the effectiveness of the proposed motion planning method.This study serves as a basic theoretical study of the structure optimization and control strategy of M-CDLR. | Jinghang Li Keyi Wang Yanzhuo Wang Chao Wang | 2023 | Journal of Bionic Engineering2023，20，4： | 0 |
| 8 | Vertical Schottky ultraviolet photodetector based on graphene and top–down fabricated GaN nanorod arrays显示文摘GaN has been widely used in the fabrication of ultraviolet photodetectors because of its outstanding properties.In this paper,we report a graphene–GaN nanorod heterostructure photodetector with fast photoresponse in the UV range.GaN nanorods were fabricated by a combination mode of dry etching and wet etching.Furthermore,a graphene–GaN nanorod heterostructure ultraviolet detector was fabricated and its photoelectric properties were measured.The device exhibits a fast photoresponse in the UV range.The rising time and falling time of the transient response were 13 and 8 ms,respectively.A high photovoltaic responsivity up to 13.9 A/W and external quantum efficiency up to 479%were realized at the UV range.The specific detectivity D*=1.44×10^(10) Jones was obtained at–1 V bias in ambient conditions.The spectral response was measured and the highest response was observed at the 360 nm band. | Xuemin Zhang Changling Yan Jinghang Yang Chao Pang Yunzhen Yue Chunhong Zeng Baoshun Zhang | 2022 | Journal of Semiconductors2022，43，6： | 0 |
| 9 | Humanistic cultural tradition background and research of similarities and differences between Chinese and Western music显示文摘 | Jinghang Zou | 2014 | International Journal of Technology Management2014，，6： | 0 |
| 10 | Recent advances in biopolymer-based hemostatic materials显示文摘Hemorrhage is the leading cause of trauma-related deaths,in hospital and prehospital settings.Hemostasis is a complex mechanism that involves a cascade of clotting factors and proteins that result in the formation of a strong clot.In certain surgical and emergency situations,hemostatic agents are needed to achieve faster blood coagulation to prevent the patient from experiencing a severe hemorrhagic shock.Therefore,it is critical to consider appropriate materials and designs for hemostatic agents.Many materials have been fabricated as hemostatic agents,including synthetic and naturally derived polymers.Compared to synthetic polymers,natural polymers or biopolymers,which include polysaccharides and polypeptides,have greater biocompatibility,biodegradability and processibility.Thus,in this review,we focus on biopolymer-based hemostatic agents of different forms,such as powder,particles,sponges and hydrogels.Finally,we discuss biopolymer-based hemostatic materials currently in clinical trials and offer insight into next-generation hemostats for clinical translation. | Marvin Mecwan Jinghang Li Natashya Falcone Menekse Ermis Emily Torres Ramon Morales Alireza Hassani Reihaneh Haghniaz Kalpana Mandal Saurabh Sharma Surjendu Maity Fatemeh Zehtabi Behnam Zamanian Rondinelli Herculano Mohsen Akbari Johnson V.John Ali Khademhosseini | 2022 | Regenerative Biomaterials2022，9，1： | 0 |
| 11 | Karst Cave as Terrestrial Simulation Platform to Test and Design Human Base in Lunar Lava Tube显示文摘Developing efficient approaches to building a suitable environment for humans on the moon play a key role in future long-term sustainable lunar exploration activities,which has motivated many countries to propose diverse plans to build a lunar base.The lava tubes discovered by the Kaguya mission offer huge potential sites to host such bases.Through computation and analysis,we show that lunar lava tubes offer stable structures,suitable temperatures,low radiation doses,and low meteorite impact rates.We summarize previous research results and put forward the conditions to find and use a suitable lunar lava tube for human habitation on the moon.The establishment of extraterrestrial bases still faces many technical bottlenecks;many countries have begun to use the earth’s environment for extraterrestrial exploration and simulation missions.In this regard,we proposed the idea of using the Earth’s karst caves to simulate extraterrestrial lava tubes,selected caves in Chongqing as the simulation site,and demonstrated the feasibility from both structural and environmental aspects.Finally,we proposed a karst cave simulation platform with three main research directions:cave sealing technology,efficient daylight system,and internal circulation research of artificial ecosystems containing natural soil and rock.We hope to promote the development of related research on extraterrestrial bases through simulation experiments. | Jinghang Ding Gengxin Xie Linli Guo Xin Xiong Ya Han Xi Wang | 2022 | Space(Science & Technology)2022，，1： | 0 |
| 12 | Relation or Influence of RVOTO in the Inflammatory Response to Reoxygenation in Patients with Tetralogy of Fallot显示文摘Background:This study evaluated differential inflammatory response to cardiopulmonary bypass reoxygenation in tetralogy of Fallot repair.Methods:We performed a retrospective study at a cardiovascular center from 2012 to 2018,including 500 patients aged 1 week–18 years who received complete repair of tetralogy of Fallot.Patients were grouped according to tertiles of preoperative RVOT gradient on echocardiography into mild,moderate,and severe stenosis.We measured the highest perfusate oxygenation(PpO_(2))during aortic occlusion as independent variable.Primary outcome was systemic inflammatory response syndrome(SIRS)within 7 days postoperatively or the time of death or discharge.Results:Overall,rate of SIRS was 24.2% without significant differences among three groups(P>0.05).Older age,male,and smaller indexed left ventricular end-diastolic volume is independent risk factor of SIRS.There were significant interactions between RVOT stenosis and PpO2 on SIRS(P interaction=0.011):higher PpO_(2) was associated with a greater SIRS risk among combined moderate and severe stenotic children(OR 1.46395%CI[1.080,1.981]per-SD increase,P=0.014)but not among mild stenotic children(OR 0.900[0.608,1.333]per-SD increase;P=0.600),independent of covariates.Conclusion:The association of PpO_(2) with SIRS was modified by RVOT obstruction severity in tetralogy of Fallot repair. | Hong Liu Luyao Ma Jinghang Li Bingqi Sun Siqiang Zheng Yongfeng Shao | 2021 | Congenital Heart Disease2021，16，5： | 0 |
| 13 | BacFlash signals acid-resistance gene expression in bacteria显示文摘Intracellular pH(pHi)homeostasis is crucial for cellular functions and signal transduction across all kingdoms of life.In particular,bacterial pHi homeostasis is important for physiology,ecology,and pathogenesis.Here we report an exquisite bacterial acid-resistance(AR)mechanism in which proton leak elicits a pre-emptive AR response.A single bacterial cell undergoes quantal electrochemical excitation,termed“BacFlash”,which consists of membrane depolarization,transient pHi rise,and bursting production of reactive oxygen species.BacFlash ignition is dictated by acid stress in the form of proton leak across the plasma membrane and the rate of BacFlash occurrence is reversely correlated with the pHi buffering capacity.Through genome-wide screening,we further identify the ATP synthase Fo complex subunit a as the putative proton sensor for BacFlash biogenesis.Importantly,persistent BacFlash hyperactivity activates transcription of a panel of key AR genes and predisposes the cells to survive imminent extreme acid stress.These findings demonstrate a prototypical coupling between electrochemical excitation and nucleoid gene expression in prokaryotes. | Di Wu Wenfeng Qi Wei Nie Zhengyuan Lu Yongxin Ye Jinghang Li Tao Sun Yufei Zhu Heping Cheng Xianhua Wang | 2021 | Cell Research2021，31，6： | 0 |
| 14 | Challenges in Li-ion battery high-voltage technology and recent advances in high-voltage electrolytes显示文摘The electrolyte directly contacts the essential parts of a lithium-ion battery,and as a result,the electrochemical properties of the electrolyte have a significant impact on the voltage platform,charge discharge capacity,energy density,service life,and rate discharge performance.By raising the voltage at the charge/discharge plateau,the energy density of the battery is increased.However,this causes transition metal dissolution,irreversible phase changes of the cathode active material,and parasitic electrolyte oxidation reactions.This article presents an overview of these concerns to provide a clear explanation of the issues involved in the development of electrolytes for high-voltage lithium-ion batteries.Additionally,solidstate electrolytes enable various applications and will likely have an impact on the development of batteries with high energy densities.It is necessary to improve the high-voltage performance of electrolytes by creating solvents with high thermal stabilities and high voltage resistance and additives with superior film forming performance,multifunctional capabilities,and stable lithium salts.To offer suggestions for the future development of high-energy lithium-ion batteries,we conclude by offering our own opinions and insights on the current development of lithium-ion batteries. | Jianguo Liu Baohui Li Jinghang Cao Xiao Xing Gan Cui | 2024 | Journal of Energy Chemistry2024，91，4： | 0 |
| 15 | Photodegradation of benzothiazole ionic liquids catalyzed by titanium dioxide and silver-loaded titanium dioxide显示文摘In recent years,ionic liquids(ILs)have been widely used in extraction,synthesis,electrochemistry and other fields.Meanwhile,the environmental impact of ILs has been attracting a lot of attention,and eco-friendly treatment for ILs is becoming a necessary subject.In this study,photocatalytic degradations of benzothiazole ILs catalyzed by titanium dioxide(TiO2)and silver-loaded titanium dioxide(Ag/TiO2)were studied for the first time.The degradation of benzothiazole hexafluorophosphate([C4 Bth]PF6)could reach more than 99%within 240 min with the catalysis of TiO2.To improve catalytic efficiency,Ag/TiO2 was synthesized and characterized by UV–Vis diffuse reflectance absorption spectra(DRS)and X-ray photoelectron spectroscopy(XPS).The degradation of[C4 Bth]PF6 could reach more than 99%within 120 min in the degradation catalyzed by Ag/TiO2.The photodegradation products of benzothiazole ILs are composed of inorganic substances or organic substances with simpler structures,which are easier to decompose and less toxic.The degradation system proposed by this study could provide a simple,green,safe,and economical method for the efficient treatment of benzothiazole ILs. | Jinghang Li Huimin Zang Shun Yao Zicheng Li Hang Song | 2020 | Chinese Journal of Chemical Engineering2020，28，5： | 0 |
| 16 | Static workspace analysis of a multi-robot collaborative towing system with floating base显示文摘The static workspace of the multi-robot collaborative towing system with floating base was analyzed.The spacial configuration of the system was built,and the system was divided into three types according to the actuation.The kinematic and dynamic models of the floating base and the towing system were established,respectively,by using the Newton-Euler equation.Then the static workspace of the system was analyzed,and the specific steps to solve the workspace with the improved Monte Carlo method were obtained.Finally,the static workspaces of three types of systems were solved though actual simulation calculation,the simulation results show that the improved Monte Carlo method can get a workspace with higher precision compare to the traditional Monte Carlo method.Results of this study lay a basis for the subsequent trajectory plan,stability analysis and configuration optimization of the system. | Cheng Su Jinghang Li Wangcai Ding Zhigang Zhao | 2021 | International Journal of Modeling, Simulation, and Scientific Computing2021，12，2： | 0 |
| 17 | Histopathological Features Predicting Long-term Clinical Outcomes in Patients with Vanishing Bile Duct Syndrome显示文摘Background and Aims:The clinicopathological features and long-term outcomes of patients with vanishing bile duct syndrome(VBDS)have yet to be elucidated.The study aims to investigate these features and identify factors associated with poor prognosis.Methods:This multicenter retrospective study recruited patients with liver biopsy-proven VBDS who were followed up at five hospitals in northern China from January 2003 to April 2022.Clinical and pathological data at time of biopsy were reviewed.Clinical outcomes including cirrhosis,decompensation events,liver transplantation(LT),and liver-related death were recorded.Cox regression analysis was used to identify the risk factors associated with poor outcomes.Results:A total of 183 patients were included.The median age was 47 years,with 77.6%being women.During a median follow-up of 4.8 years,88 patients developed compensated or decompensated cirrhosis,27 died,and 15 received LT.Multivariate Cox regression analysis showed that hepatocellular cholestasis(HR 2.953,95%CI:1.437–6.069),foam cells(HR 2.349,95%CI:1.092–5.053),and advanced fibrosis(HR 2.524,95%CI:1.313–4.851)were independent predictors of LT or liver-related deaths.A nomogram formulated with the above factors showed good consistency with a concordance index of 0.746(95%CI:0.706–0.785).Conclusions:Nearly half of VBDS patients studied progressed to end-stage liver disease and 23%of them had LT or liver-related death within two years of diagnosis.Hepatocellular cholestasis,foam cells and advanced fibrosis rather than the degree of bile duct loss or underlying etiologies were independently associated with poor prognosis in VBDS patients. | Tingting Lv Haitian Yu Xiao Han Aileen Wee Jimin Liu Min Li Jinghang Xu Xiaoli Hu Jia Li Weijia Duan Tailing Wang Jidong Jia Xinyan Zhao | 2023 | Journal of Clinical and Translational Hepatology2023，11，5： | 0 |
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