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| 1 | Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells显示文摘导致的 pluripotent 干细胞(iPSCs ) 的产生为心疾病,屏蔽的药和潜在的自体同源的心脏的新生的调查打开了新大街。然而,他们的申请被导出 iPSC 的 cardiomyocytes (iPS 厘米) 的低效的心脏的区别,高写在行间可变性,和差的成熟妨碍。为 iPSCs 的心脏的区别和成熟识别有效 inducers 并且阐明机制,我们系统地在各种各样的鼠科的(m) iPSCs 上屏蔽了十六 cardiomyocyte inducers 并且发现没有自发的心脏性的潜力,仅仅维生素酸(AA ) 一致地并且要用体力地包括八提高了十一根线的心脏的区别。我们然后优化了治疗条件并且表明了那区别天 2-6,为心脏的祖先房间(CPC ) 的说明的经期,是一批评时间让 AA 生效。这被 AA 增加了表示的事实进一步证实心血管然而并非 mesodermal 标记。显著, AA 处理导致了近似 7.3 褶层(miPSCs ) 和 30.2 褶层(人的 iPSCs ) 在 iPS 厘米的收益扩充。如此的效果经由 MEK-ERK1/2 小径被归因于 CPC 的增长的特定的增加由通过支持骨胶原合成。另外,导致 AA 的 cardiomyocytes 显示出更好的 sarcomeric 组织并且提高了行动潜力和钙 transients 的回答到 β肾上腺素能并且 muscarinic 刺激。这些调查结果证明 AA 是合适的 cardiomyocyte inducer 让 iPSCs 普遍,简单地改进心脏的区别和成熟。这些调查结果也强调由在指导 pluripotent 干细胞的心脏的区别操作细胞外的微型环境刺激 CPC 增长的重要性。 | Nan Cao Zumei Liu Zhongyan Chen Jia Wang Taotao Chen Xiaoyang Zhao Yu Ma Lianju Qin Jiuhong Kang Bin Wei Liu Wang Ying Jin Huang-Tian Yang | 2012 | Cell Research2012，22，1： | 28 |
| 2 | Application of the Credit Metrics in the Credit Risk Management of Commercial Banks显示文摘Credit risk is one of the main risks the commercial banks faces all over the world,especially in the risk structure of the banks of China.In order to control credit risk more scientifically,we shall connect the qualitative analysis and the quantitative analysis.Put forward by J.P.Morgan Credit Metrics model is the application of the VaR in the field of credit risk,showing great advantage in quantitative bonds and credit risk of loan.This paper studies the Credit Metrics model and analyzes the hypothesis and framework of this model,attempting to explore the application of the model in China in order to promote the realization of the risk quantification of the commercial banks of China. | Yu Jiuhong Lu Yue Wang Zhibo | 2015 | 学术界2015，，5： | 2 |
| 3 | Preparation of porous titania sol-gel matrix for immobilization of horseradish peroxi- dase by a vapor deposition method 显示文摘 | Jiuhong Yu Huangxian Ju | 2002 | Anal Chem2002，74，14： | 1 |
| 4 | Preparation of porous titania sol-gel matrix for immobilization of horseradish peroxidase by a vapor deposition method显示文摘 | YU Jiuhong JU Huangxian | 2002 | Anal Chem2002，74，： | 1 |
| 5 | Mediator - free Phenol Sensor Based on Titania Sol - gel Encapsulation Matrix for Immobilization of Tyrosinase by a Vap or Deposition Method 显示文摘 | Yu Jiuhong Liu Songqin Ju Huangxian | 2003 | Biosens Bioelectron2003，19，5： | 1 |
| 6 | Glucose sensor for flow injection analysis of serum glucose based on immobilization of glucose oxidase in titania sol-gel membrane显示文摘 | Yu Jiuhong Liu Songqin Ju Huangxian | 2003 | Biosensors and Bioelectronics2003，19，4： | 1 |
| 7 | Amperometric biosensor for hydrogen peroxide based on hemoglobin entrapped in titania sol gel film显示文摘 | Yu Jiuhong Ju Huangxian | 2003 | Analytica Chimica Acta2003，486，2： | 1 |
| 8 | Renewable Phenol Biosensor Based on Tyrosinase Colloidal Gold Modified Carbon Paste Electrode 显示文摘 | Liu Songqin Yu Jiuhong Ju Huangxian | 2003 | J Electoranal Chem2003，540，2： | 1 |
| 9 | Renewable phenol biosensor based on a tyrosinase - colloidal gold modified carbon paste electrode显示文摘 | LIU Songqing YU Jiuhong JU Huangxian | 2003 | J Electroanal Chem2003，540，： | 1 |
| 10 | Renewable phenol biosensor based on tyrosinase-colloidal gold modified carbon paste electrode显示文摘 | LIU Songqin YU Jiuhong JU Huangxian | 2003 | J Electroanal Chem2003，540，： | 1 |
| 11 | Platelet - derived growth factor signaling and human cancer显示文摘 | Jiuhong Yu Carolyn Ustach Hyeong - Reh Choi Kim | 2003 | J Biochem and Mol Biol2003，36，1： | 1 |
| 12 | Renewable phenol biosensor based on a tyrosinase-colloidal gold modified carbon paste electrode 显示文摘 | Songqin Liu Jiuhong Yu Huangxian Ju | | Journal of Electroanalytical Chemistry0，540，： | 1 |
| 13 | Development on Laser Cladding Ceramic Coating显示文摘The latest progress and research status of laser cladding ceramic coating was summarized. Technique characteristics and influence factors of laser cladding technique were introduced. Laser cladding technique includes the mixing method and laser irradiation. The mixing method can be classified as pre-coating method and synchronization method. The technique parameters include size of facula, scanning speed, cladding sector and times, adding quantity of powder, thickness of coating and quantity of joint coating. The results show that proper technique parameters can be controlled in order to acquire high quality laser cladding coating. Strengthened effect mechanism of rare earth additive is concluded, and the main effects of rare earth additive are micro-alloying, purifying boundary, fining crystal grains, improving crystal boundary, restraining columnar crystal growing. The development of laser cladding ceramic coating research was discussed. | Qian Jiuhong Li Xikun Qiu Guanming Qiu Tai Zhao Haitao Yu Honghao | 2006 | Journal of Rare Earths2006，24，z1： | 0 |
| 14 | LIMIT CYCLES FOR A CLASS OF NONPOLYNOMIAL PLANAR VECTOR FIELDS (II)显示文摘In this paper, the problem of limit cycles for a class of nonpolynomial planar vector felds is investigated. First, based on Liapunov method theory, we obtain some sufcient conditions for determining the origin as the critical point of such nonpolynomial planar vector felds to be the focus or center. Then, using Dulac criterion, we establish some sufcient conditions for the nonexistence of limit cycles of this nonpolynomial planar vector felds. And then, according to Hopf bifurcation theory, we analyze some sufcient conditions for bifurcating limit cycles from the origin. Finally, by transforming the nonpolynomial planar vector felds into the generalized Li′enard planar vector felds, we discuss the existence, uniqueness and stability of limit cycles for the former and latter planar vector felds. Some examples are also given to illustrate the efectiveness of our theoretical results. | Gaoying Zhang Jia Du Yu Wang Jiuhong Zhou | 2013 | Annals of Differential Equations2013，29，3： | 0 |
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