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| 1 | High-density Linkage Map of Cultivated Allotetraploid Cotton Based on SSR, TRAP, SRAP and AFLP Markers显示文摘一张高密度的连锁图为从在 Gossypium hirsutum L 之间的 cultivatedallotetraploid 种类的一个种间的十字导出的一张 F_2 人口被构造。并且 G.barbadense L。从种间的十字的 186 个 F_2 个人的一个总数“ CRI36 x 哈尔 7124' 是在包括一个新奇标记系统的 1 252 多态的 loci 的 genotyped,目标区域扩大多型性(陷井) 。地图由 1 097 个标记组成,包括 697 简单顺序重复(SSR ) , 171 个陷井, 129 顺序相关的放大多型性, 98 放大 fragmentlengthpolymorphisms,和二个词法标记,并且跨越了 4 有 4.1cM 的平均遗传距离的 536.7 厘米每标记。用在染色体之中的 45 复制 SSR loci, 13 同源染色体中的 11 个在四倍体棉花被识别。这张地图将为量的特点 loci 并且在棉花的分子的繁殖印射的高分辨率提供一个必要资源。 | Jiwen Yu Shuxun Yu Cairui Lu Wu Wang Shuli Fan Meizhen Song Zhongxu Lin Xianlong Zhang Jinfa Zhang | 2007 | Journal of Integrative Plant Biology2007，49，5： | 29 |
| 2 | Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription显示文摘为 histone crotonylation 的酶和读者蛋白质上的最近的研究在抄写支持 histone crotonylation 的功能。然而,为 histone decrotonylation (HDCR ) 负责的酶仍然保持糟糕定义。而且,如果 histone crotonylation 从生理地重要、机能上地不同或对 histone acetylation 冗余,它尚待坚定。这里我们一级 histone deacetylases (HDAC ) 而非 sirtuin 家庭 deacetylases (SIRT ) 是主要 histone decrotonylases 的现在的证据,和那 histone crotonylation 象在哺乳动物的房间的 histone acetylation 一样动态。尤其是,我们与损害 HDAC 产生了新奇 HDAC1 和 HDAC3 异种但是未经触动的 HDCR 活动。用这些异种,我们证明在哺乳动物的房间的选择 HDCR 与宽广 transcriptional 压抑和 crotonylation 然而并非 acetylation 读者蛋白质的减少的倡导者协会相关。而且,我们证明那 histone crotonylation 被充实在并且为老鼠的自强要求了胚胎的干细胞。 | Wei Wei Xiaoguang Liu Jiwei Chen Shennan Gao Lu Lu Huifang Zhang Guangjin Ding Zhiqiang Wang Zhongzhou Chen Tieliu Shi Jiwen Li Jianjun Yu Jiemin Wong | 2017 | Cell Research2017，27，7： | 18 |
| 3 | Heterostructure design of Fe^(3)N alloy/porous carbon nanosheet composites for efficient microwave attenuation显示文摘The self-dissipation and attenuation capacity of materials play an important role in realizing efficient electromagnetic absorption,in this case,the roles of macroscopic composition and micro-structure should be emphasized simultaneously in the reasonable design of microwave absorbent.Given that,Fe_(3)N alloy embedded in two-dimensional porous carbon composites were fabricated via facile sol-gel and sacrificial template methods.Satisfactorily,the magnetic/dielectric materials combination and porous structure introduction are conductive to the optimization of impedance matching property,as result of the enhancement of microwave absorption capacity.In addition,sufficient magnetic loss capacity,strong conductivity as well as polarization attenuation bring about the outstanding microwave absorbing performance with an effective absorption bandwidth of 6.76 GHz and a minimum reflection loss value of-65.6 d B.It is believed that this work not only lay a foundation to achieve microwave response materials in a wide frequency range,but also emphasize the significant role of the component selection and structural design. | Weihua Gu Xiaoqing Cui Jing Zheng Jiwen Yu Yue Zhao Guangbin Ji | 2021 | Journal of Materials Science & Technology2021，，8： | 3 |
| 4 | Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOFI/KDMlb显示文摘 | Qi Zhang Shankang Qi Mingchu Xu Lin Yu Ye Tao Zengqin Deng Wei Wu Jiwen Li Zhongzhou Chen Jiemin Wong | 2013 | Cell Research2013，23，2： | 2 |
| 5 | Effects of composite oxide scale on oxidation resistance of superalloy K273显示文摘A Si-containing K273 superalloy was made using intermediate frequency induction furnace in the study. In the testing of oxidation resistance,the oxidation process of the alloy specimens during the testing at 900℃ for 500 h was examined by oxidation weight gain method.The morphology and composition of the oxide scales were determined using scanning electron microscope(SEM)and X-ray diffraction(XRD),respectively.The effects of the transferring of ions and electrons on the oxidation resistance were further analyzed microscopically by semiconductor oxide models.The results show that the composite oxide scales consist of Cr2O3,SiO2 and spinel- type oxide MCr2O4,with flat and compact structure,and fine grains in uniform distribution.All of these endow the superalloy K273 with strong oxidation resistance.The reason for the powerful oxidation resistance of the composite scale is that the formation process of P+N type semiconductor oxide enables to consume most of the surplus negative and positive ions in the oxide scales,which makes the number of the mobile ions and electrons dropped enormously,and the transfer rate of them falls heavily.So the oxidation rate of the metal phase in the alloy matrix is reduced significantly. | Wang Haitao Tan Jiwen Chu Zhong Yu Huashun | 2012 | China Foundry2012，9，2： | 1 |
| 6 | Mapping quantitative trait loci for cottonseed oil, protein and gossypol content in a Gossypium hirsutum?×?Gossypium barbadense backcross inbred line population显示文摘 | Jiwen Yu Shuxun Yu Shuli Fan Meizhen Song Honghong Zhai Xingli Li Jinfa Zhang | 2012 | Euphytica2012，，2： | 1 |
| 7 | The Synergism between Methanogens and Methanotrophs and the Nature of their Contributions to the Seasonal Variation of Methane Fluxes in a Wetland:The Case of Dajiuhu Subalpine Peatland显示文摘Wetland ecosystems are the most important natural methane(CH_(4))sources,whose fluxes periodically fluctuate.Methanogens(methane producers)and methanotrophs(methane consumers)are considered key factors affecting CH_(4)fluxes in wetlands.However,the symbiotic relationship between methanogens and methanotrophs remains unclear.To help close this research gap,we collected and analyzed samples from four soil depths in the Dajiuhu subalpine peatland in January,April,July,and October 2019 and acquired seasonal methane flux data from an eddy covariance(EC)system,and investigated relationships.A phylogenetic molecular ecological networks(pMENs)analysis was used to identify keystone species and the seasonal variations of the co-occurrence patterns of methanogenic and methanotrophic communities.The results indicate that the seasonal variations of the interactions between methanogenic and methanotrophic communities contributed to CH_(4)emissions in wetlands.The keystone species discerned by the network analysis also showed their importance in mediating CH_(4)fluxes.Methane(CH_(4))emissions in wetlands were lowest in spring;during this period,the most complex interactions between microbes were observed,with intense competition among methanogens while methanotrophs demonstrated better cooperation.Reverse patterns manifested themselves in summer when the highest CH_(4)flux was observed.Methanoregula formicica was negatively correlated with CH_(4)fluxes and occupied the largest ecological niches in the spring network.In contrast,both Methanocella arvoryzae and Methylocystaceae demonstrated positive correlations with CH_(4)fluxes and were better adapted to the microbial community in the summer.In addition,soil temperature and nitrogen were regarded as significant environmental factors to CH_(4)fluxes.This study was successful in explaining the seasonal patterns and microbial driving mechanisms of CH_(4)emissions in wetlands. | Luwen WANG Jiwen GE Liang FENG Yaoyao LIU Yu LI Jiumei WANG Xiang XIAO Zhiqi ZHANG | 2022 | Advances in Atmospheric Sciences2022，39，8： | 1 |
| 8 | CHARACTERISTICS OF LOW TEMPERATURE ION PLATING TiN COATINGS显示文摘CHARACTERISTICSOFLOWTEMPERATUREIONPLATINGTiNCOATINGSLiuJiwenTianjinUniversityYuLiInstituteofCorosionandProtectionofMetals,Ac... | Liu, Jiwen Yu, Li | 1998 | Chinese Journal of Mechanical Engineering1998，11，2： | 0 |
| 9 | A targeted QTL analysis for fiber length using a genetic population between two introgressed backcrossed inbred lines in upland cotton(Gossypium hirsutum)显示文摘Cotton fiber is the most important natural raw material for the textile industry, and fiber length(FL) is one of the most important traits in cotton.Quantitative trait locus(QTL)mapping based on high-density genetic maps is an efficient approach to identify genetic regions for FL.In our study, two backcrossed inbred lines(BILs) were chosen as parents to construct a high-density genetic map in F2 which was used to fine map FL QTL in F2:3 population.The genetic map had a total size of 3462.8 cM, containing 9182 singlenucleotide polymorphisms(SNPs) based on genotyping-by-sequencing.Two FL related stable QTL were identified on two chromosomes(qFL-A08–1 on A08 and qFL-D03–1 on D03),and qFL-A08–1 was confirmed by a meta-analysis.Utilizing previously obtained RNA-seq data for the two BILs and qRT-PCR analysis, two candidate genes annotated as cytochrome b5(CB5, Gh_A08 G1729) and microtubule end-binding 1 C(EB1C, Gh_D03 G0232) that may regulate FL during the fiber elongation stage were identified.In addition, nine recombination hotspots in this population were found.The results of this study will provide an important foundation for further studies on the molecular and genetic regulation of fiber elongation. | Guoyuan Liua Wenfeng Pei Dan Li Jianjiang Ma Yupeng Cui Nuohan Wang Jikun Song Man Wu Libei Li Xinshan Zang Shuxun Yu Jinfa Zhang Jiwen Yu | 2019 | The Crop Journal2019，7，3： | 0 |
| 10 | MYC promotes global transcription in part by controlling P-TEFb complex formation via DNA-binding independent inhibition of CDK9 SUMOylation显示文摘MYC is an oncogenic transcription factor with a novel role in enhancing global transcription when overexpressed. However, how MYC promotes global transcription remains controversial. Here, we used a series of MYC mutants to dissect the molecular basis for MYC-driven global transcription. We found that MYC mutants deficient in DNA binding or known transcriptional activation activities can still promote global transcription and enhance serine 2 phosphorylation(Ser2P) of the RNA polymerase(Pol) II Cterminal domain(CTD), a hallmark of active elongating RNA Pol II. Two distinct regions within MYC can promote global transcription and Ser2P of Pol II CTD. The ability of various MYC mutants to promote global transcription and Ser2P correlates with their ability to suppress CDK9 SUMOylation and enhance positive transcription elongation factor b(P-TEFb) complex formation. We showed that MYC suppresses CDK9 SUMOylation by inhibiting the interaction between CDK9 and SUMO enzymes including UBC9 and PIAS1. Furthermore, MYC's activity in enhancing global transcription positively contributes to its activity in promoting cell proliferation and transformation. Together, our study demonstrates that MYC promotes global transcription, at least in part, by promoting the formation of the active P-TEFb complex via a sequence-specific DNA-binding activity-independent manner. | Qingqing Guan Zhaosu Chen Fang Yu Lingling Liu Yuanyong Huang Gang Wei Cheng-Ming Chiang Jiemin Wong Jiwen Li | 2023 | Science China(Life Sciences)2023，66，9： | 0 |
| 11 | 阳离子通道TRPV在醛缩酶和AMPK感知葡萄糖过程中起必须的作用显示文摘文章简介在激活AMPK的溶酶体途径感应葡萄糖供给下降的过程中,果糖-1,6-二磷酸醛缩酶(aldolase)起关键作用。然而,醛缩酶是如何把其与果糖-1,6-二磷酸结合的减少的信息传导引起AMPK活化的机制还尚未清楚。 | Mengqi Li Chen-Song Zhang Yue Zong Jin-Wei Feng Teng Ma Meiqin Hu Zhizhong Lin Xiaotong Li Changchuan Xie Yaying Wu Dong Jiang Ying Li Cixiong Zhang Xiao Tian Wen Wang Yanyan Yang Jie Chen Jiwen Cui Yu-Qing Wu Xin Chen Qing-Feng Liu Jianfeng Wu Shu-Yong Lin Zhiyun Ye Ying Liu Hai-Long Piao Li Yu Zhuan Zhou Xiao-Song Xie D.Grahame Hardie 林圣彩 | 2020 | 科学新闻2020，，2： | 0 |
| 12 | Long-term outcomes and prognosis factors of vagus nerve stimulation in patients with refractory epilepsy显示文摘Background:Vagus nerve stimulation(VNS)is an effective treatment for patients with refractory epilepsy,yet with varied predictive factors and heterogeneous long-term outcomes.Adjustment of VNS parameters is critical for obtaining favorable efficacy.In this study,we aimed to investigate the long-term outcomes and the possible predictive factors of VNS in patients with refractory epilepsy.Methods:Eighty-six patients(59 males and 27 females)who underwent VNS implantation for treatment of refractory epilepsy between May 2016 and May 2017 at five Epilepsy Centers were enrolled.The clinical data,including sex,age at epilepsy onset,VNS implantation,epilepsy duration,seizure type,MRI findings,history of neurosurgical operations,and responder rate(responders were those with≥50%seizure reduction),were analyzed.Results:Four-year follow-up data were available for 76 patients(53 males and 23 females).The mean current intensity at the last follow-up was 1.8±0.3 mA(range:0.75–2.5 mA).The mean seizure reduction was 36.2%at 6 months,38.5%at 1 year,69.4%at 3 years,and 56.7%at 4 years.A favorable outcome of≥50%reduction in seizure frequency occurred in 40.0%of the patients at 6 months,55.9%at 1 year with 4 patients being seizure-free,63.2%at 3 years with 5 patients being seizure-free,and 68.4%at 4 years with 5 patients being seizure-free.Earlier onset age(P<0.001)and shorter duration(P=0.042)were associated with favorable prognosis.Compared with generalized tonicclonic seizures,tonic seizures had a favorable outcome(P=0.026).Twenty-three patients underwent neurosurgical operations before VNS implantation,and the responder rate was 60.9%at the last follow-up.Conclusions:VNS is an adjunctive and effective treatment for patients with refractory epilepsy who are not good candidates for surgical resection or have failed to respond to surgical treatment.The stimulation efficacy increases over time after implantation,and earlier exposure to VNS improves the prognosis. | Cuiping Xu Hua Lin Jiwen Xu Xiaohua Zhang Guiliang Hao Qiang Qiang Liu Chengyun Ding Shan Wang Quanjun Zhao Xiaojun Bai Kui Chen Duanyu Ni Yongjie Li Tao Yu Yuping Wang | 2022 | Acta Epileptologica2022，5，3： | 0 |
| 13 | Fragment Angular Distributions for 1000 MeV ~40(Ar)+^(209)Bi Reaction显示文摘Fragment Angular Distributions for 1000 MeV~40(Ar)+^(209)Bi Reaction￥YuXian,ChenKeliang,LiuGuoxing,ZhangJiwen,SunTongyu,WuDing... | Yu Xian, Chen Keliang, Liu Guoxing, Zhang Jiwen, Sun Tongyu,Wu Dingqing, Zhao Lili, Zang Xiang, Yin Xinmin and Qin Zhi | 1994 | IMP & HIRFL Annual Report1994，，0： | 0 |
| 14 | SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation显示文摘 | Fang Yu Guang Shi Shimeng Cheng Jiwei Chen Shwu-Yuan Wu Zhiqiang Wang Nansong Xia Yunhao Zhai Zhenxing Wang Yu Peng Dong Wang James X. Du Lujian Liao Sheng-Zhong Duan Tieliu Shi Jinke Cheng Cheng-Ming Chiang Jiwen Li Jiemin Wong | 2018 | Cell Research2018，28，6： | 0 |
| 15 | Chinese expert recommendations on ketogenic diet therapy for super-refractory status epilepticus显示文摘Super-refractory status epilepticus(SRSE)is a serious and life-threatening neurological condition.Ketogenic diet(KD)is a diet characterized by high fat,low carbohydrate,and moderate protein.As KD shows effectiveness in controlling seizures in more than half of SRSE patients,it can be a treatment option for SRSE.Currently,KD treatment for SRSE is based on personal experience and observational evidence has been published.In the context of a lack of a validated guideline,we convened a multicenter expert panel within the China Association Against Epilepsy(CAAE)Ketogenic Diet Commission to work out the Chinese expert recommendations on KD for SRSE.We summarize and discuss the latest clinical practice of KD for SRSE in critical care settings.Recommendations are given on patient selection,the timing of KD,diet implementation,and follow-up.More research data are needed in this area to support better clinical practice. | Xin Tong Qianyun Cai Dezhi Cao Lifei Yu Dan Sun Guang Yang Jiwen Wang Hua Li Zengning Li Juan Wang Shaoping Huang Meiping Ding Fang Fang Qun Wang Rong Luo Jianxiang Liao Jiong Qin | 2022 | Acta Epileptologica2022，5，1： | 0 |
| 16 | Calculation Program of Exciton Model for Transmission Equation of Exciton State Intensity Distribution显示文摘Calculation Program of Exciton Model for Transmission Equation of Exciton State Intensity DistributionCalculationProgramofExc... | Yu Xian Zheng Jiwen Liu Guoxing and Chen Keliang | 1995 | IMP & HIRFL Annual Report1995，，0： | 0 |
| 17 | A comparative analysis of small RNAs between two Upland cotton backcross inbred lines with different fiber length: Expression and distribution显示文摘The cotton fiber is the most important raw material for the textile industry and an ideal model system for studying cell elongation. However, the genetic variation of fiber elongation in relation to miRNA is poorly understood. A high-throughput comparative RNA-seq of two lines differing in fiber length(FL) from a backcross inbred line(BIL)population of G. hirsutum × G. barbadense revealed differentially expressed(DE) miRNAs and their targets in rapidly elongating fibers. A real-time quantitative PCR analysis was further performed to validate the results. A total of 463(including 47 DE) miRNAs were identified,and seven DE miRNAs were co-localized with seven FL quantitative trait loci(QTL)identified in the G. hirsutum × G. barbadense population. Of 82(including 21 DE) targets identified, nine(including one DE) were also co-localized with the seven FL QTL. The relationship between the allopolyploid and its diploid ancestral species with respect to miRNAs and their targets was also characterized. These results will facilitate the understanding of the molecular genetic mechanism of fiber elongation with regards to miRNAs in cotton. | Guoyuan Liu Man Wu Wenfeng Pei Xihua Li Nuohan Wang Jianjiang Ma Xinshan Zang Shuxun Yu Jinfa Zhang Jiwen Yu | 2019 | The Crop Journal2019，7，2： | 0 |
| 18 | Genome-wide association study of micronaire using a natural population of representative upland cotton(Gossypium hirsutum L.)显示文摘Background: Micronaire is a comprehensive index reflecting the fineness and maturity of cotton fiber.Micronaire is one of the important internal quality indicators of the cotton fiber and is closely related to the value of the cotton fiber.Understanding the genetic basis of micronaire is required for the genetic improvement of the trait.However,the genetic architecture of micronaire at the genomic level is unclear.The present genome-wide association study(GWAS)aimed to identify the genetic mechanism of the micronaire trait in 83 representa:tive upland cotton lines grown in multiple environments.Results GWAS of micronaire used 83 upland cotton accessions assayed by a Cotton 63 K Illumina Infinium single nucleotide polymorphism(SNP)array.A total of 11 quantitative trait loci(QTLs)for micronaire were detected on 10 chromosomes.These 11 QTLs included 27 identified genes with specific expression patterns.A novel QTL,qFM-A12–1,included 12 significant SNPs,and GhFLA9 was identified as a candidate gene based on haplotype block analysis and on strong and direct linkage disequilibrium between the significantly related SNPs and gene.GhFLA9 was expressed at a high level during secondary wall thickening at 20∼25 days post-anthesis.The expression level of GhFLA9 was significantly higher in the low micronaire line(Msco-12)than that in the high micronaire line(Chuangyou-9).Conclusions: This study provides a genetic reference for genetic improvement of cotton fiber micronaire and a foundation for verification of the functions of GhFLA9. | SONG Jikun PEI Wenfeng MA Jianjiang YANG Shuxian JIA Bing BIAN Yingying XIN Yue WU Luyao ZANG Xinshan QU Yanying ZHANG Jinfa WU Man YU Jiwen | 2021 | Journal of Cotton Research2021，4，2： | 0 |
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