|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 多囊卵巢综合征未治疗妇女分泌期子宫内膜中类固醇激素受体、辅助调节因子及子宫容受性相关分子研究显示文摘Objective: To evaluate gene and protein expression of steroid receptors, nuclear receptor coregulators, and uterine receptivity markers in midsecretory phase endometria from untreated women with polycystic ovary syndrome (PCOS).Design: Case-control study. Setting: Hospital research unit. Patient(s): Eight patients with PCOS and eight fertile women of similar age to those with PCOS. In-tervention(s): Endometrial samples were obtained from women with PCOS (PCOSE) and normal (NE)- women during the midsecretory phase of the menstrual cycle. Main Outcome Measure(s): Expression studies (immunohistoch-emistry, reverse transcription-polymerase chain reaction [RT- PCR] and Western blot). Result(s): Endometria from PCOS exhibit higher levels of messenger RNA (mRNA) and protein for estrogen receptor α and coactivators than NE. Epithelial cells had a greater expression of progesterone receptor in PCOSE, whereas, no differences were observed in gene and protein expression of the nuclear corepressor (NcoR)- and the antiadhesion molecule mucin type- 1 (MUC- 1) between PCOSE and NE. Immunodetection for the coactivator ARA70 was higher in PCOSE than in NE; in contrast, expression of β 3- integrin in epithelia was lower in PCOSE than in control endometria. Conclusion(s): The higher response to steroid hormones of endometria from untreated PCOS-women induces diminished expression of β 3 integrin, which partially explain implantation failure in PCOS patients. | Quezada S. Avellaira C. Johnson M.C. M. Vega 李跃萍 | 2006 | 世界核心医学期刊文摘(妇产科学分册)2006，0，8： | 7 |
| 2 | Mayo临床中心肺癌CT筛查的长期效果评价显示文摘目的分析Mayo临床中心肺癌CT筛查研究受试者的单组个体数据,评价筛查的长期效果,同时对比评价已知肺癌模拟模型和应用相同数据建立的不同模型之间的差别。方法本研究经伦理审查委员会批准,并且符合HIPPA。在Mayo临床中心,由1520例肺癌筛查受试者(年龄50~85岁,吸烟或有吸烟史)的匿名资料组成肺癌政策模型.包括微观的肺癌发展模拟模型、CT筛查所见、治疗结果和长期结果。模型用于预测单位研究小组内(包括连续5a肺癌年筛查和不进行肺癌筛查)肺癌的诊断和死亡。 | P.M. McMahon C.Y. Kong B.E. Johnson M.C. Weinstein J.C. Weeks K.M.Kuntz 高莉(译) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 5 |
| 3 | Differential effect of age on survival in advanced NSCLC in women versus men: Analysis of recent Eastern Cooperative Oncology Group (ECOG) studies, with and without bevacizumab显示文摘 | H.A. Wakelee S.E. Dahlberg J.R. Brahmer J.H. Schiller M.C. Perry C.J. Langer A.B. Sandler C.P. Belani D.H. Johnson | 2011 | Lung Cancer2011，，3： | 3 |
| 4 | Genetical genomics of Th1 and Th2 immune response in a baboon model of atherosclerosis risk factors显示文摘 | A. Vinson J.E. Curran M.P. Johnson T.D. Dyer E.K. Moses J. Blangero L.A. Cox J. Rogers L.M. Havill J.L. VandeBerg M.C. Mahaney | 2011 | Atherosclerosis2011，，2： | 1 |
| 5 | Thermal properties of carbon nanotubes and nanotube-based materials显示文摘 | J. Hone M.C. Llaguno M.J. Biercuk A.T. Johnson B. Batlogg Z. Benes J.E. Fischer | 2002 | Applied Physics A Materials Science & Processing2002，，3： | 1 |
| 6 | Rb–Sr ages from phengite inclusions in garnets from high pressure rocks of the Swiss Western Alps显示文摘 | Caroline M.C. de Meyer Lukas P. Baumgartner Brian L. Beard Clark M. Johnson | 2014 | Earth and Planetary Science Letters2014，，： | 1 |
| 7 | 采用辅助生殖技术的双卵双胎妊娠与染色体异常、宫内失调和单绒毛膜双胎胎盘形成 | Yoon G. Beischel L.S. Johnson J.P. Jones M.C. 平智广 | 2005 | 世界核心医学期刊文摘(儿科学分册)2005，0，8： | 0 |
| 8 | 乳房过早发育患者活化的GNAS1基因突变 | Román R. Johnson M.C. Codner E. F.Cassorla 郭战宏 | 2005 | 世界核心医学期刊文摘(儿科学分册)2005，0，1： | 0 |
| 9 | 原发性肺静脉狭窄显示文摘原发性肺静脉狭窄(PVS)是一种死亡率极高的罕见疾病。对其预后预测因素或合适的干预时间尚所知甚少。在儿童心脏护理协会数据库(n=98126)中搜索1982-2002年间因PVS或闭锁而行心导管治疗或外科手术的患者。排除具有完全或部分肺静脉回流异常、三房心、心房转位术史或肺移植史的患者。通过发送问卷至儿童心脏护理协会各机构来获取附加数据。总共31例患者被确认为原发性PVS。除外肺移植,31例中有16例接受干预以减轻PVS。 | Holt D.B. Moller J.H. Larson S. Johnson M.C. 杜媛 | 2007 | 世界核心医学期刊文摘(心脏病学分册)2007，3，7： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员