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| 1 | A new bone repair scaffold combined with chitosan/ hydroxyapatite and sustained releasing icariin显示文摘Icariin, a plant-derived flavonol glycoside, has been proved as an osteoinductive agent for bone tissue engineering. A new bone repair scaffold was generated by thorough mixing of icariin and chitosan/ hydroxyapatite (icariin-CS/HA) using freeze-drying technigue. Characteristics of morphology, mechanical properties, biocompatibility, drug release behavior and bone repair abilities in vivo were evaluated. The results show that drug loading process of icariin did not affect physical structure of CS/HA composite significantly but decreased mechanical properies of CS/HA composite, which happened with a high dosage; icariin-CS/HA had favorable cell compatibility and promoted osteogenic differentiation of hBMSCs; the controlled release of icariin was satisfactory and the release retained after 90 d in vitro. In addition, icariin-CS/HA scaffolds had favorable osteoconduction and osteoinduction in vivo, and could fill bone defect sites and stimulate newborn bone tissues formation at early stage. On the basis of these data, icariin-CS/HA is believed to be an optical bone repair scaffold for tissue engineering. | WU Tao NAN KaiHui CHEN JingDi JIN Dan JIANG Shan ZHAO PeiRan XU JunChang DU Hao ZHANG XiaoQiang LI JianWei PEI GuoXian | 2009 | Chinese Science Bulletin2009，54，17： | 14 |
| 2 | A New Species of Huaxiapterus (Pterosauria: Pterodactyloidea) from the Lower Cretaceous of Western Liaoning, China with Comments on the Systematics of Tapejarid Pterosaurs显示文摘tapejarid 翼龙的新种, Huaxiapterus corollatus sp。nov。根据一个将近完全的颅骨被树立并且从辽宁省的更低的 CretaceousJiufotang 形成张贴头部的骨骼,中国。Huaxiapterus corollatus sp。nov。被一个塑造和斧的矩形的过程在切牙骨上描绘,其短轴对 premaxillae 的前面的边缘垂直。除了这个过程,颅骨的另外的人物如此的著名计算机生产厂商他在 nasoantorbital 窗的前面的边缘和切牙骨的前面的边缘之间的猪嘴的宽度类似于 Huaxiapterus jii 的。Huaxiapterus 和第二 Chinesetapejarid, Sinopterus,和 Tapejara 一样的份额几独特头部的人物和这三个类看起来比到另外的 azhdarchoids 与对方有关仔细是更多。Chinesetapejarids (Sinopterus 和 Huaxiapterus ) 相对伸长颅骨和微弱地发达的头部的冠并且似乎少些比 Tapejara 被发源,与它的更短的、更深的颅骨和大头部的冠。Tupuxuarids (Tupuxuara 和 Thalassodromeus ) 经常是在家庭 Tapejaridae 的联系 withtapejarids,但是因为一些种系发生的分析支持了与 Azhdarchidae 配对 tupuxuarids,这种关系是争论的。我们建议 thatTapejaridae 被限制为 Tapejara, Sinopterus 和 Huaxiapterus。 | Lü Junchang JIN Xingsheng David M. UNWIN ZHAO Lijun AZUMA Yoichi JI Qiang | 2006 | Acta Geologica Sinica(English Edition)2006，80，3： | 5 |
| 3 | Thermal conductivity enhancement in thermal grease containing different CuO structures 显示文摘 | Yu We'i Zhao Junchang Wang Mingzhu | 2015 | Nanoscale Res Lett2015，10，1： | 1 |
| 4 | Radiation-induced one-pot synthesis of grafted covalent organic frameworks显示文摘Post-synthetic functionalization of covalent organic frameworks(COFs)is an alternative way to enhance and broaden their properties and potential applications.However,the chemical functionalization of COFs is a great challenge because traditional procedures are often time-and energy-consuming,while the crystallinity of COFs can be damaged under harsh conditions.Here we report the in-situ introduction of functional graft chains onto the skeleton of COFs during the synthesis process through the combination of radiation-induced synthesis and graft polymerization techniques under ^(60)Co gamma-ray radiation.The synthesis and functionalization of COFs are simultaneously accomplished in a chemical system under ambient conditions yielding a large number of different functionalized COFs.The obtained carboxyl-functionalized COFs exhibit excellent radioactive uranium removal capabilities from aqueous solution with fast uptake dynamics,high adsorption capacity,and excellent selectivity over other competing metal ions. | Mingxing Zhang Mengjia Yuan Xiaofang Zhao Junchang Chen Linwei He Qianhong Gao Jiangtao Hu Guozhong Wu Zhifang Chai Shuao Wang | 2023 | Science China Chemistry2023，66，6： | 0 |
| 5 | Fast filtering false active subspaces for efficient high dimensional similarity processing显示文摘The query space of a similarity query is usually narrowed down by pruning inactive query subspaces which contain no query results and keeping active query subspaces which may contain objects corre-sponding to the request. However,some active query subspaces may contain no query results at all,those are called false active query subspaces. It is obvious that the performance of query processing degrades in the presence of false active query subspaces. Our experiments show that this problem becomes seriously when the data are high dimensional and the number of accesses to false active sub-spaces increases as the dimensionality increases. In order to solve this problem,this paper proposes a space mapping approach to reducing such unnecessary accesses. A given query space can be re-fined by filtering within its mapped space. To do so,a mapping strategy called maxgap is proposed to improve the efficiency of the refinement processing. Based on the mapping strategy,an index structure called MS-tree and algorithms of query processing are presented in this paper. Finally,the performance of MS-tree is compared with that of other competitors in terms of range queries on a real data set. | WANG GuoRen YU Ge, XIN JunChang ZHAO YuHai ZHANG EnDe | 2009 | Science in China(Series F)2009，52，2： | 0 |
| 6 | Amyloid precursor-like protein 2 C-terminal fragments upregulate S100A9 gene and protein expression in BV2 cells显示文摘The murine microglial cell line BV2 has neuroprotective effects, but is toxic to neurons by secreting inflammatory cytokines, and is an important target in the treatment of nerve inflammation and neurodegenerative diseases. In the present study, we observed the effects of transfecting three amyloid precursor-like protein 2(APLP2) C-terminal fragments(CTFs; C57, C50 and C31) in the p EGFP-N1 vector on S100A9 expression in BV2 cells. Reverse transcription-PCR, western blot assay and immunocytochemistry revealed that S100A9 protein and m RNA expression was greater in BV2 cells after CTF transfection than after mock transfection with an empty vector. Furthermore, transfection of full-length APLP2-751 resulted in low levels of S100A9 protein expression. Our results show that APLP2-CTFs upregulate S100A9 protein and m RNA expression in BV2 cells, and identify a novel pathway involved in neuronal injury and apoptosis, and repair and protection in Alzheimer's disease. | Guangzhe Li Hui Chen Lin Cheng Rongjie Zhao Junchang Zhao Yanji Xu | 2014 | Neural Regeneration Research2014，9，21： | 0 |
| 7 | Rational Design of Plasmonic Metal Nanostructures for Solar Energy Conversion显示文摘Plasmonic metal nanostructures,possessing unique surface plasmon resonance properties,show excellent capabilities for light trapping and coupling.On this basis,various plasmonic metal nanostructures offer extraordinary opportunities to promote the conversion efficiency of solar energy to electric energy,hydrogen energy or thermal energy,and so on.In this review article,we highlight a number of recent research achievements on the rational design of plasmonic metal nanostructures so as to maximize the utilization of the entire solar spectrum.Compared with single metal nanoparticles,multiplex(such as multicompositions,sizes,or shapes)nanoparticle structures emphasize advantages in broadening the absorption range and improving light-utilization efficiency.This review concludes with discussions regarding challenges in this research field and proposals of prospects for future directions. | Yawen Wang Junchang Zhang Wenkai Liang He Yang Tianfu Guan Bo Zhao Yinghui Sun Lifeng Chi Lin Jiang | 2022 | CCS Chemistry2022，4，4： | 0 |
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