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| 1 | Effect of autotransfusion system on tumor recurrence and survival in hepatocellular carcinoma patients显示文摘AIM:To investigate the therapeutic efficacy and safety of continuous autotransfusion system(CATS) during liver transplantation of hepatocellular carcinoma patients.METHODS:Eighty-three hepatocellular carcinoma(HCC) patients who underwent liver transplantation with intraoperative CATS(n = 24,CATS group) and without(n = 59,non-CATS group) between April 2006 and November 2011 at the Liver Transplant Institute of Inonu University were analyzed retrospectively.Postoperative HCC recurrence was monitored by measuring alpha-fetoprotein(AFP) levels at 3-mo intervals and performing imaging analysis by thoracoabdominal multidetector computed tomography at 6-month intervals.Inter-group differences in recurrence and correlations between demographic,clinical,and pathological data were assessed by ANOVA and χ 2 tests.Overall and disease-free survivals were calculated by the univariate Kaplan-Meier method.RESULTS:Of the 83 liver transplanted HCC patients,89.2% were male and the overall mean age was 51.3 ± 8.9 years(range:18-69 years).The CATS and nonCATS groups showed no statistically significant differences in age,sex ratio,body mass index,underlying disease,donor type,graft-to-recipient weight ratio,Child-Pugh and Model for End-Stage Liver Disease scores,number of tumors,tumor size,AFP level,Milan and University of California San Francisco selection criteria,tumor differentiation,macrovascular invasion,median hospital stay,recurrence rate,recurrence site,or mortality rate.The mean follow-up time of the nonCATS group was 17.9 ± 12.8 mo,during which systemic metastasis and/or locoregional recurrence developed in 25.4% of the patients.The mean follow-up time for the CATS group was 25.8 ± 15.1 mo,during which systemic metastasis and/or locoregional recurrence was detected in 29.2% of the patients.There was no significant difference between the CATS and non-CATS groups in recurrence rate or site.Additionally,no significant differences existed between the groups in overall or disease-free survival.CONCLUSION:CATS is a safe procedure and may decrease the risk of tumor recurrence in HCC patients. | Sami Akbulut Cuneyt Kayaalp Mehmet Yilmaz Volkan Ince Dincer Ozgor Koray Karabulut Cengiz Eris Huseyin Ilksen Toprak Cemalettin Aydin Sezai Yilmaz | 2013 | World Journal of Gastroenterology2013，19，10： | 17 |
| 2 | Functional roles and clinical values of insulin-like growth factor-binding protein-5 in different types of cancers显示文摘Insulin-like growth factor-bindin g proteins (IGFBPs) are critical regulators of the mitogenic activity of insulin-like growth factors (IGFs). IGFBP5, one of these IGFBPs, has special structural features, including a nuclear transport domain, heparin-binding motif, and IGF/extracellular matrix/acid-labile subunit-binding sites. Furthermore, IGFBP5 has several functional effects on carcinogenesis and even normal cell processes, such as cell growth, death, motility, and tissue remodeling. These biological effects are sometimes related with IGF (IGF-dependent effects) and sometimes not (IGF-independent effects). The functional role of IGFBP5 is most likely determined in a cell-type and tissue-type specific manner but also depends on cell context, especially in terms of the diversity of interacting proteins and the potential for nuclear localization. Clinical findings show that IGFBP5 has the potential to be a useful clinical biomarker for predicting response to therapy and clinical outcome of cancer patients. In this review, we summarize the functional diversity and clinical importance of IGFBP5 in different types of cancers. | Gökçe Güllü Sevgi Karabulut Mustafa Akkiprik | 2012 | Chinese Journal of Cancer2012，31，6： | 8 |
| 3 | Drought analysis in Antakya-Kahramanmaras Graben,Turkey显示文摘The most parts of the Earth experience precipitation variability as a part of their normal climates over both short- and long-time periods. These variations of precipitation will have unpredictable and perhaps unexpectedly extreme consequences(such as drought and flood) with respect to frequency and intensity for many regions of the Earth. Because of high precipitation fluctuations, the Mediterranean region is also the areas of the world sensitive to precipitation changes which often involve frequent drought conditions in Turkey. In this study, drought conditions at annual, seasonal and monthly time scales over the period of 1975–2010 were examined for Antakya-Kahramanmara? Graben which is located in the eastern part of the Mediterranean region of Turkey. Application of appropriate measures to analyze and monitor droughts is recognized as a major challenge to scientists involved in atmospheric studies. Standardized Precipitation Index(SPI) and cumulative deviation curve techniques were used to determine drought conditions. Results indicated that the study area presented a cyclic pattern of variations with alternating drier and wetter years. From analyses of annual, seasonal and monthly drought series it can be seen that precipitation characteristic of the area is changing. By the results, apparent wet and dry periods can be distinguished. This study also indicated that precipitation totals of winter, spring and summer seasons were slightly decreased during the study period. Drought frequency was increased especially for the northern part of the area in the last ten years. Drought periods were divided into 1982–1985, 1999–2002 and 2004–2008, respectively. According to our analyses, the time scale of 1999–2002 was the driest period in the most of the graben area. The study area, which covers agriculturally important fertile alluvial plains, will experience increasing pressure on its water resources because of its growing population and industry, ever-larger demands for intensive agricultural activities, and frequent drought events. | Murat KARABULUT | 2015 | Journal of Arid Land2015，7，6： | 6 |
| 4 | Feature Selection for Malware Detection on the Android Platform Based on Differences of IDF Values显示文摘Android is the mobile operating system most frequently targeted by malware in the smartphone ecosystem,with a market share significantly higher than its competitors and a much larger total number of applications.Detection of malware before being published on official or unofficial application markets is critically important due to the typical end users'widespread security inadequacy.In this paper,a novel feature selection method is proposed along with an Android malware detection approach.The feature selection method proposed in this study makes use of permissions,API calls,and strings as features,which are statically extractable from the Android executables(APK files)and it can be used in a machine learning process with different algorithms to detect malware on the Android platform.A novel document frequency-based approach,namely Delta IDF,was designed and implemented for feature selection.Delta IDF was tested upon three universal benchmark datasets that contain Android malware samples and highly promising results were obtained by using several binary classification algorithms. | Gokcer Peynirci Mete Eminagaoglu Korhan Karabulut | 2020 | Journal of Computer Science & Technology2020，35，4： | 4 |
| 5 | Single port laparoscopic liver surgery:A minireview显示文摘Nowadays,the trend is to perform surgeries with'scarless'incisions.In light of this,the single-port laparoscopic surgery(SPLS)technique is rapidly becoming widespread due to its lack of invasiveness and its cosmetic advantages,as the only entry point is usually hidden in the umbilicus.The interest in'scarless'liver resections did not grow as rapidly as the interest in other scarless surgeries.Hepatopancreatobiliary surgeons are reluctant to operate a malignant lesion through a narrowincision with limited exposure.There are concerns over adverse oncological outcomes for single-port laparoscopic liver resections(SPL-LR)for hepatocellular carcinoma or metastatic colorectal cancer.In addition,getting familiar with using the operating instruments through a narrow incision with limited exposure is very challenging.In this article,we reviewed the published literature to describe history,indications,contraindications,ideal patients for new beginners,technical difficulty,advantages,disadvantages,oncological concern and the future of SPL-LR. | Ilhan Karabicak Kagan Karabulut | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，12： | 3 |
| 6 | Determinants and definition of abdominal obesity as related to risk of diabetes, metabolic syndrome and coronary disease in Turkish men: A prospective cohort study显示文摘 | Altan Onat Hüseyin Uyarel Gülay Hergen? Ahmet Karabulut Sinan Albayrak Günay Can | 2006 | Atherosclerosis2006，，1： | 2 |
| 7 | Estimation of concentration and temperature profiles for methane-steam reforming reaction in a porous catalyst显示文摘 | Levent M Budak G Karabulut A | 1998 | Fuel Processing Technol1998，55，： | 2 |
| 8 | Clinical implication of hematological indices in the essential hypertension显示文摘Prognostic value of haematological indices,especially red cell distribution width,neutrophil lymphocyte ratio and mean platelet volume,was reported with numerous investigations in miscellaneous cardiovascular settings.Their major prognostic value was linked to oxidative stress and inflammation since their level was correlated with major inflammatory markers such as high sensitive C-reactive protein and interleukins.Oxidative stress and chronic inflammation are also postulated as the main pathophysiologic mechanism of essential hypertension(HT) and its vascular complication.Recently,correlation between HT and haematological parameters was searched in numerous studies,which has made the topic more popular.Herein,we reveal the correlation between haematological indices and HT and we also demonstrate the clinical implication of this correlation.Impaired haematological parameters may strongly indicate hypertensive end-organ damage. | Ahmet Karabulut Aytac Karadag | 2015 | World Journal of Hypertension2015，5，2： | 2 |
| 9 | 1999年土耳其Izmit M_W7.6地震的持续成核过程显示文摘实验室和理论研究表明,地震之前会出现一个渐进性的滑动不稳定阶段,在此期间,断层缓慢滑动,而后突然加速并最终导致动态破裂。本文中,我们报道了迄今记录最为完整的大地震之一,即1999年土耳其Izmit MW7.6地震之前出现了持续时间很久的源自震源的地震信号。这种信号包含一连串的地震破裂,破裂随时间和低频地震噪声的增加而加速。这些观测结果表明,此次地震之前在脆性地壳底部出现了44min的缓慢滑动。滑动最初呈缓慢加速,然后在地震发生前2min内又突然加速。 | Michel Bouchon Hayrullah Karabulut Mustafa Aktar Serdar zalaybey Jean Schmittbuhl Marie-Paule Bouin 左玉玲 | 2011 | 国际地震动态2011，，5： | 2 |
| 10 | Protection by flee oxygen radical scavenging enzymes against salicylate-induced embryonic malformation in vitro显示文摘 | Karabulut AK Ulger H Pratten MK | 2004 | Toxicol In Vitro2004，，4： | 1 |
| 11 | Clopidogrel does not increase bleeding and allogenic blood transfusion in coronary artery surgery 显示文摘 | Karabulut H Toraman F Evrenkaya S | 2004 | Eur J Cardiothorac Surg2004，25，3： | 1 |
| 12 | Correlation between red cell distribution width and coronary ectasia in the acute myocardial infarction显示文摘 | Karabulut A Uzunlar B | 2012 | Clin Appl Thromb Hemost2012，18，5： | 1 |
| 13 | SPME-GC-MS detection of volatile compounds in apricot varieties显示文摘 | Gokbulut I Karabulut I | 2012 | Food Chemistry2012，132，2： | 1 |
| 14 | MR imaging of the chest using a contrast-enhanced breath-hold modified three-di- mensional gradient-echo technique: comparison with two-dimen sional gradient-echo technique and multidetector CT显示文摘 | Karabulut N Martin D R Yang M | 2002 | AJR2002，179，12： | 1 |
| 15 | Modified Limberg transposition flap in the treatment of pilonidal sinus disease显示文摘 | B. Kaya C. Eris S. Atalay O. Bat N. E. Bulut B. Mantoglu K. Karabulut | 2012 | Techniques in Coloproctology2012，，1： | 1 |
| 16 | Clinical significance of serum interleukin-18 (IL-18) levels in patients with gastric cancer显示文摘 | Faruk Tas Ceren Tilgen Yasasever Senem Karabulut Didem Tastekin Derya Duranyildiz | 2015 | Biomedicine & Pharmacotherapy2015，，： | 1 |
| 17 | The growth promoting effects of bFGF,PD ECGF and VEGF on cultured postimplantation rat embryos deprived of serum fractions显示文摘 | Ulger H Karabulut A K Pratten M K | 2000 | J Anat2000，197，2： | 1 |
| 18 | Preparation of arsenic trioxide loaded microemulsion and its enhanced eytotoxicity on MCF-7 breast carcinoma cell line 显示文摘 | Karasulu HY Karabulut B Kantarci G et ol | 2004 | Drug Deliv2004，11，6： | 1 |
| 19 | N-terminal proBNP plasma levels correlate with severity of mitral stenosis显示文摘 | Iltumur K Karabulut A Yokus B | 2005 | Heart Valve Dis2005，14，6： | 1 |
| 20 | Longterm outcomes of intraoperative and perioperative albendazole treatment in hepatic hydatidosis:single center experience显示文摘 | Karabulut K Ozbalci GS Kesicioglu T | 2014 | Ann Surg Treat Res2014，87，2： | 1 |
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