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| 1 | Metabolic syndrome as a risk factor for gallstone disease显示文摘AIM: To establish an association between the presence of metabolic syndrome and the development of gallstone disease.METHOIDS: We carried out a cross-sectional study in a check-up unit in a university hospital in Mexico City. We enrolled 245 subjects, comprising 65 subjects with gallstones (36 women, 29 men) and 180 controls (79women and 101 men without gallstones). Body mass index, waist circumference, blood pressure, plasma insulin, and serum lipids and lipoproteins levels were measured. Insulin resistance was calculated by homeostasis model assessment. Unconditional logistic regressionanalysis (univariate and multivariate) was used to calculate the risk of gallstone disease associated with the presence of at least three of the criteria (Adult Treatment Panel Ⅲ). Analyses were adjusted for age and sex.RESULTS: Among 245 subjects, metabolic syndrome was present in 40% of gallstone disease subjects, compared with 17.2% of the controls, adjusted by age and gender (odds ratio (OR) = 2.79; 95%CI, 1.46-5.33; P = 0.002),a dose-dependent effect was observed with each component of metabolic syndrome (OR = 2.36, 95%CI, 0.72-7.71;P = 0.16 with one component and OR = 5.54, 95%CI,1.35-22.74; P = 0.02 with four components of metabolic syndrome). Homeostasis model assessment was significantly associated with gallstone disease (adjusted OR = 2.25;95%CI, 1.08-4.69; P = 0.03).CONCLUSION: We conclude that as for cardiovascular disease and diabetes mellitus, gallstone disease appears to be strongly associated with metabolic syndrome. | Nahum Méndez-Sánchez Norberto C. Chavez-Tapia Daniel Motola-Kuba Karla Sanchez-Lara Guadalupe Ponciano-Rodríguez Héctor Baptista Martha H. Ramos Misael Uribe | 2005 | World Journal of Gastroenterology2005，11，11： | 32 |
| 2 | Adiponectin as a protective factor in hepatic steatosis显示文摘AIM: Obesityand insulin resistance (IR) are closely related to hepatic steatosis (HS), and adiponectin is a hepatic insulin sensitizer that has important effects in liver function.This study aims at investigating the relationship between serum adiponectin concentration and the presence of HS.METHODS: We carried out a cross-sectional study in a check-up unit of a University Hospital in Mexico City. We enrolled 196 subjects, comprising 98 subjects with HS (27 women, 71 men) and 98 controls (37 women and 61men). Anthropometric, metabolic and biochemical variables were measured in the two groups. Serum adiponectin and leptin concentrations were determined,their association with grade of HS tested, and concentrations,according to quartiles, compared between cases and controls. χ2 analysis for linear trends was used to test for a dose-response relationship and logistic regression analysis was conducted to test for a protective effect of adiponectin.RESULTS: The HS subjects were older and more obese than controls, with a central obesity pattern. In the fourth quartile of adiponectin concentrations, HS was less common and severe. In a multivariate model of the fourth quartile of the adiponectin concentrations, we observed a protective effect (OR = 0.17, 95%CI: 0.04-0.67, P= 0.01).In subjects with more severe HS, we observed higher leptin concentrations, and caloric intakes, total fat and iron consumption were higher than in controls.CONCLUSION: The results of the present study suggest that a high serum concentration of adiponectin is associated with a protective effect against HS. | Nahum Méndez-Sánchez Norberto C.Chávez-Tapia Antonio R.Villa Karla Sánchez-Lara Daniel Zamora-Valdés Martha H.Ramos Misael Uribe | 2005 | World Journal of Gastroenterology2005，11，12： | 12 |
| 3 | Acoustic radiation force impulse imaging (ARFI) for non-invasive detection of liver fibrosis: examination standards and evaluation of interlobe differences in healthy subjects and chronic liver disease显示文摘 | Thomas Karlas Cornelia Pfrepper Johannes Wiegand Christian Wittekind Marie Neuschulz Joachim M?ssner Thomas Berg Michael Tr?ltzsch Volker Keim | 2011 | Scandinavian Journal of Gastroenterology2011，，12： | 4 |
| 4 | Non-invasive evaluation of hepatic manifestation in Wilson disease with transient elastography, ARFI, and different fibrosis scores显示文摘 | Thomas Karlas Maria Hempel Michael Tr?ltzsch Dominik Huster Peter Günther Hannelore Tenckhoff Joachim M?ssner Thomas Berg Volker Keim Johannes Wiegand | 2012 | Scandinavian Journal of Gastroenterology2012，，11： | 2 |
| 5 | Signal peptidases显示文摘 | Paetzel M Karla A Strynadka N C Dalbey R E | 2002 | Chem Rev2002，102，： | 1 |
| 6 | Piezoelectric actuators as synthetic jets: Cavity dimension effects 显示文摘 | POORNA M KARLA M ALI R | 2007 | Journal of Intelligent Material Systems and Structures2007，18，11： | 1 |
| 7 | Effect of Inhibition Treatment, Type of Inocula, and Incubation Temperature on Batch H2 Production from Organic Solid Waste显示文摘 | Idania V V Elvira R L Karla M P | 2006 | Biotechnol Bioeng2006，95，3： | 1 |
| 8 | Modeling the IRS telephone taxpayer information system显示文摘 | Harris Carl M Hoffman Karla L Saunders Patsy B | 1987 | Operations Research1987，35，： | 1 |
| 9 | Conceptual Organization at 6 and 8 Years of Age:Evidence from the SemanticPriming of Object Decisions显示文摘 | Hashimoto N Karla K Graham M A | 2007 | Journal of Speech Language and Hearing Research2007，50，： | 1 |
| 10 | Xerogelencapsulated W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus performs asymmetric reduction of hydropbobic ketanes in organic solvents显示文摘 | MUSA M M KARLA I Z F CLAIRE V | 2007 | Angewandte Chemie2007，46，17： | 1 |
| 11 | Lexical-semantic Organization in Bilingual Children:Evidence from A RepeatedWord Association Task显示文摘 | Li Sheng Karla K M Viorica M | 2006 | Journal of Speech Language and Hearing Research2006，49，： | 1 |
| 12 | Porcine endogenous retroviruses:no infection in patients treated with a bioreactor based on porcine liver cells显示文摘 | Irgang M Sauer IM Karlas A | 2003 | J Clin Virol2003，28，： | 1 |
| 13 | Porcine endogenous retroviruses:no infection in patients treated with a bioreactor based on porcine liver cells显示文摘 | Irgang M Sauer IM Karlas A | 2003 | J Clin Virol2003，28，2： | 1 |
| 14 | Comparison of stubbing and the double swab method for collecting offender epithelial material from a victim's skin显示文摘 | Karla G Saskia M | 2011 | Forensic Sci Int Gen?et2011，10，： | 1 |
| 15 | Mechanised nanoparticles for drug delivery 显示文摘 | Coti M E B Karla K Monty Long Ambrogio Michael W | 2009 | Nanoseale2009，1，： | 1 |
| 16 | Electrochemical impedance spectroscopy study during acceler- ated life test of conductive oxides: Yi (Ru+Yi+Ce)0:-system 显示文摘 | Leonardo M Da Silva Karla C Femandes Luiz A De Faria et a l | 2004 | Electrochemica Acta2004，49，27： | 1 |
| 17 | Adsorption studies of methylene blue and gentian violet on sugarcane bagasse modified with EDTA dianhydride (EDTAD) in aqueous solutions: Kinetic and equilibrium aspects显示文摘 | Karla Aparecida Guimar?es Gusm?o Leandro Vinícius Alves Gurgel Tania Márcia Sacramento Melo Laurent Frédéric Gil | 2013 | Journal of Environmental Management2013，，： | 1 |
| 18 | Broadly tunable, mode-hop-tuned cw optical parametric oscillator based on periodically poled lithium niobate 显示文摘 | Bisson Scote E Armstrong Karla M Kulp Thomas J | 2001 | Applied Optics2001，40，33： | 1 |
| 19 | Relationship between botanical origin and aatioxidants vitamins of bee-coUected Ix)lien显示文摘 | KARLA C L OLIVEIRA S MARINA M | 2009 | Qulmiea Nova2009，32，5： | 1 |
| 20 | The influence of total solids con- tent and initial pH on batch biohydrogcn production by solid substratc fermentation of agroindustriaI wastes显示文摘 | Paula N Robledo Narvaez Karla M MuflozPaez Hector M Poggi Varaldo | 2013 | Journal of Environmental Management2013，128，： | 1 |
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