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| 1 | Scaffolding protein Gab1 regulates myeloid dendritic cell migration in allergic asthma显示文摘气喘是在多重基因、环境的因素之中包含复杂相互影响的普通过敏混乱。最近的研究作为一个新奇气喘危险性因素识别了人的 GAB1 的基因变体。然而,在肺的 Gab1 的功能仍然保持大部分未经勘探。在这研究,我们首先在尖锐恶化期间从气喘的病人在外部血 mononuclear 房间观察了 Gab1 水平的举起与康复相比。有在 myeloid 的有选择地破坏的 Gab1 的老鼠树枝状的房间(mDCs ) 更加在气喘的试验性的模型稀释了过敏发炎。进一步的调查在 Gab1 缺乏的 mDCs 的调停 CCL19 的移植揭示了突出的减小到排干淋巴节点和驾驶 Th2 的适应激活的随后的缺陷。机械学地, Gab1 是在气喘的回答期间调整 mDC 移植的 CCL19/CCR7 chemokine 轴的一个必要部件。一起,这些调查结果在肺为 Gab1 的角色提供第一条证据,给我们气喘的致病的更深的理解。 | Yun Zhang Yun Xu Shuwan Liu Xiaohong Guo Dong Cen Jiaqi Xu Heyuan Li Kaijun Li Chunlai Zeng Linrong LU Yiting Zhou Huahao Shen Hongqiang Cheng Xue Zhang Yuehai Ke | 2016 | Cell Research2016，26，11： | 3 |
| 2 | Studies of the Geodesic Acoustic Mode Zonal Flow in HL-2A Tokamak Plasmas显示文摘 | ZHAO Kaijun DONG Jiaqi YAN Longwen HONG Wenyu QIAN Jun CHENG Jun YU Deliang YANG Qingwei DING Xuantong LIU Yong PAN Chuanhong | 2006 | Southwestern Institute of Physics Annual Report2006，，1： | 2 |
| 3 | Experimental study on multi-split air conditioner with digital scroll com- pressor显示文摘 | Qiu Tu Kaijun Dong Deqiu Zou | 2011 | Applied Thermal Engineering2011，31，1415： | 1 |
| 4 | Experimental study on multi-split air conditioner with digital scroll com- pressor 显示文摘 | Tu Qiu Dong Kaijun Zou Deqiu | 2011 | Applied thermal engineering2011，31，： | 1 |
| 5 | Three Dimensional Identification of Zonal Flows in the HL-2A Tokamak显示文摘 | YAN Longwen HONG Wenyu LAN Tao ZHAO Kaijun DONG Jiaqi LIU Adi YU Changxuan QIAN Jun CHENG Jun YU Deliang YANG Qingwei DING Xuantong LIU Yong PAN Chuanhong | 2006 | Southwestern Institute of Physics Annual Report2006，，1： | 0 |
| 6 | Performance analysis and optimization of free cooling strategies for a liquid-cooled data center显示文摘The increasing power density of IT electronics and the enormous energy consumption of data centers lead to the urgent demand for efficient cooling technology.Due to its efficiency and safety,liquid-cooled heat sink technology may gradually replace air-cooled technology over time.With the ambient or higher water supply temperature,the liquid-cooled technology shortens the operating time of the chiller and improves its coefficient of performance,while the pump power consumption may increase for satisfying the constant cooling capacity.Therefore,it is significant to study the optimal water supply temperature to achieve energy-efficient operation of data centers.A virtual 30.1 kW data center is considered as the case,the liquid-cooled system is constructed with a combination of innovative manifold microchannel heat sink with oblique fins and indirect evaporative cooling technology to minimize energy consumption.A hybrid thermal management model integrating the heat dissipation model and the power consumption model is established by TRNSYS and FLUENT software.To the highest chip-safe operating temperature premise,the energy performance is analyzed under various water supply temperatures in Guangzhou.The result shows that only 21.5-hour mechanical cooling is needed with the 30℃server inlet temperature throughout the year.And the minimized power consumption occurs with the constant 29℃server inlet temperature.Moreover,the temperature adaptive control strategy(TACS)is adopted to test the cooling system power consumption under different regulation frequencies,and the by-week TACS can achieve another 11.5%energy saving than the minimum power consumption of the constant temperature control strategy. | Weinan Zhou Qin Sun Weimin Luo Wei Xiao Pengfei Cui Wei Wu Kaijun Dong | 2023 | Building Simulation2023，16，8： | 0 |
| 7 | Edible mushrooms as a potent therapeutics of subclinical thyroid dysfunction among adults,especially in obese individuals:a prospective cohort study显示文摘Background:Mushrooms are a good source of many nutrients which are potentially beneficial for chronic diseases.We speculated that due to its abundant nutrients edible mushrooms might have a beneficial effect on the prevention of subclinical thyroid dysfunction(SCTD).Therefore,we designed a large-scale cohort study to examine whether mushrooms consumption is a protective factor for SCTD in adults.Methods:This prospective cohort study investigated 6631 participants(mean age:(45.0±10.2)years;55.1%men).Edible mushrooms consumption was measured at baseline using a validated food frequency questionnaire.SCTD was defined as abnormal serum thyroid-stimulating hormone levels and normal free thyroxine.Cox proportional hazards regression models were used to examine the association of edible mushrooms consumption with incident SCTD.Results:During follow-up period,a total of 262 new cases of SCTD were identified,the incidence rate of subclinical hypothyroidism was 8.9/1000 person-years and subclinical hyperthyroidism was 7.2/1000 person-years.After adjusting potential confounding factors,the multivariable hazard ratios(95%confidence intervals)for subclinical hypothyroidism were 1.00(reference)for almost never,0.53(0.29,0.97)for 1-3 times/week and 0.30(0.10,0.87)for≥4 times/week(P for trend=0.02).It also showed edible mushrooms consumption was inversely associated with subclinical hypothyroidism in obese individuals but not non-obese individuals,the final hazard ratios(95%confidence intervals)were 0.14(0.03,0.73)(P for trend<0.01).Conclusions:This population-based prospective cohort study has firstly demonstrated that higher edible mushrooms consumption was significantly associated with lower incidence of subclinical hypothyroidism among general adult population,especially in obese individuals. | Juanjuan Zhang Sabina Rayamajhi Amrish Thapa Ge Meng Qing Zhang Li Liu Hongmei Wu Yeqing Gu Shunming Zhang Tingjing Zhang Xuena Wang Zhixia Cao Jun Dong Xiaoxi Zheng Xu Zhang Xinrong Dong Xing Wang Shaomei Sun Ming Zhou Qiyu Jia Kun Song Kaijun Niu | 2023 | Food Science and Human Wellness2023，12，1： | 0 |
| 8 | Fracture characterization of Asmari Formation carbonate reservoirs in G Oilfield, Zagros Basin, Middle East显示文摘The Asmari Formation in the G oilfield on the Iran-Iraq border is a fractured-porous multi-lithology mixed reservoir, for which fracture is an important factor affecting oil productivity and water cut. The characterization and modeling of fractures in the carbonate reservoir of G oilfield are challenging due to weak conventional well log responses of fractures and a lack of specific logs, such as image logs. This study proposes an integrated approach for characterizing and modeling fractures in the carbonate reservoir. The features, formation mechanism, influencing factors, and prediction methods of fractures in the Asmari Formation carbonate reservoirs of G oilfield were studied using core observation, thin section, image log, cross-dipole acoustic log (CDAL), geomechanics numerical simulation (GNS), and production data. According to CDAL-based fracture density interpretation, GNS-based fracture intensity prediction between wells, and DFN-based rock fracture properties modeling, the quantitative fracture characterization for G oilfield was realized. This research shows that the fractures in the Asamri Formation are mainly medium-to high-angle shear fractures. The substantial compression stress during the Miocene played a major role in the formation of the prominent fractures and determined their trend in the region, with primary trends of NNW-SSE and NNE-SSW. The fracture distribution has regularity, and the fractures in zone A dolomites are more highly developed than that in zone B limestones vertically. Horizontally, fractures intensity is mainly controlled by faults and structural location. The results of this study may benefit the optimization of well design during field development. From 2019 to 2021, three horizontal wells pilot tests were deployed in the fractures belt in zone A, and these fractures prominently increased the permeability of tight dolomite reservoirs. The initial production of the wells is four to five times the average production of other wells in the area, showing a good development effect. Meanwhile, the updated numerical simulation validates that the history match accuracy of water cut based on the dual-porosity model is significantly improved, proving the fracture evaluation and prediction results to be relatively reliable and applicable. | Kaijun Tong Juan He Shaoqun Dong Futing Sun Peiyuan Chen Yi Tong | 2023 | Energy Geoscience2023，4，3： | 0 |
| 9 | Experimental research of a thermoacoustic prime mover and a refrigerator显示文摘Thermoacoustic engine has been concerned recently because of its advantages of no moving parts and no pollution. A prime mover is built and its characteristics of onset temperature difference, frequency and output acoustic power are measured and analyzed. A thermoacoustic refrigerator driven by this prime mover had been tested. It may develop a temperature difference of 25 K across the regenerator and a lowest temperature of -8℃ was achieved with the frequency, input power and the static pressure 81.7 Hz, 800 W and 1 Mpa respectively. | DONG Kaijun, LI Qing, GUO Fangzhong (Cryogenic Laboratory, Huazhong University of Science and Technology Wuhan) | 2001 | Chinese Journal of Acoustics2001，20，4： | 0 |
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