|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A linear ADRC-based robust high-dynamic double-loop servo system for aircraft electro-mechanical actuators显示文摘Compared with traditional hydraulic actuators, an Electro-Mechanical Actuator(EMA)is small in size and light in weight, so it has become more widely used. Aerodynamic load on aircraft control surface varies dramatically, and a change of flight environment leads to uncertainties of motor parameters. Therefore, high-dynamic response and strong anti-disturbance capability of an EMA are of great significance for aircraft rudder control and flight attitude adjustment. In order to improve dynamic response and disturbance rejection of an EMA and simplify control parameters tuning, a robust high-dynamic servo system based on Linear Active Disturbance Rejection Control(LADRC) is proposed for an EMA employing a Permanent Magnet Synchronous Motor(PMSM).Firstly, total disturbances of the EMA are analyzed, including parameter uncertainties, load variation, and static friction. A disturbance observer based on a reduced-order Extended State Observer(ESO) is designed to improve the anti-interference ability and dynamic performance. Secondly, the servo control architecture is simplified to a double-loop system, and a composite control of position and speed with acceleration feed-forward is presented to improve the EMA frequency bandwidth.Thirdly, the ideal model of the EMA is transformed into a simple cascade integral form with a disturbance observer, which makes it convenient to analyze and design the controller. Robustness performance comparisons are realized in frequency domain. Finally, simulation and experimental results have verified the effectiveness of the proposed strategy for EMAs. | Chunqiang LIU Guangzhao LUO Zhe CHEN Wencong TU Cai QIU | 2019 | Chinese Journal of Aeronautics2019，32，9： | 18 |
| 2 | From surface to bulk modification: Plasma polymerization of amine-bearing coating by synergic strategy of biomolecule grafting and nitric oxide loading显示文摘Integration of two or more biomolecules with synergetic and complementary effects on a material surface can help to obtain multi-functions for various biomedical applications.However,the amounts of biomolecules integrated and their physiological functions are compromised due to the limited surface anchoring sites.Herein,we propose a novel concept of film engineering strategy“from surface to bulk synergetic modification”.This new concept is realized by employing the surface amine groups of plasma polymerized allylamine(PPAm)film for grafting a molecule e.g.,thrombin inhibitor,bivalirudin(BVLD),meanwhile its bulk amine groups is used as a universal depot for storing and releasing therapeutic nitric oxide(NO)gas as supplement to the functions of BVLD.It is demonstrated that such a“from surface to bulk synergetic modification”film engineering can impart the modified-substrates with anti-platelet and anti-coagulant dual functions,giving rise to a highly endotheliummimetic thromboresistant property.We believe that our research provides a very promising strategy to deliver multifunctional surface versatilely that require NO release in combination with other properties,which will find broad biomedical applications in blood-contacting devices,and et al.Moreover,it also provides a brand-new film engineering strategy for tailoring surface multi-functionalities of a wide range of materials. | Tong Yang Zeyu Du Hua Qiu Peng Gao Xin Zhao Huaiyu Wang Qiufen Tu Kaiqin Xiong Nan Huang Zhilu Yang | 2020 | Bioactive Materials2020，5，1： | 10 |
| 3 | Endothelium-Mimicking Multifunctional Coating Modified Cardiovascular Stents via a Stepwise Metal-Catechol-(Amine)Surface Engineering Strategy显示文摘Stenting is currently the major therapeutic treatment for cardiovascular diseases.However,the nonbiogenic metal stents are inclined to trigger a cascade of cellular and molecular events including inflammatory response,thrombogenic reactions,smooth muscle cell hyperproliferation accompanied by the delayed arterial healing,and poor reendothelialization,thus leading to restenosis along with late stent thrombosis.To address prevalence critical problems,we present an endothelium-mimicking coating capable of rapid regeneration of a competently functioning new endothelial layer on stents through a stepwise metal(copper)-catechol-(amine)(MCA)surface chemistry strategy,leading to combinatorial endothelium-like functions with glutathione peroxidase-like catalytic activity and surface heparinization.Apart from the stable nitric oxide(NO)generating rate at the physiological level(2:2×10^(-10) mol/cm^(2)/min lasting for 60 days),this proposed strategy could also generate abundant amine groups for allowing a high heparin conjugation efficacy up to∼1μg/cm^(2),which is considerably higher than most of the conventional heparinized surfaces.The resultant coating could create an ideal microenvironment for bringing in enhanced antithrombogenicity,anti-inflammation,anti-proliferation of smooth muscle cells,re-endothelialization by regulating relevant gene expressions,hence preventing restenosis in vivo.We envision that the stepwise MCA coating strategy would facilitate the surface endothelium-mimicking engineering of vascular stents and be therefore helpful in the clinic to reduce complications associated with stenosis. | Ying Yang Peng Gao Juan Wang Qiufen Tu Long Bai Kaiqin Xiong Hua Qiu Xin Zhao Manfred FMaitz Huaiyu Wang Xiangyang Li Qiang Zhao Yin Xiao Nan Huang Zhilu Yang | 2020 | Research2020，，1： | 8 |
| 4 | Growth of ZnO self-converted 2D nanosheet zeolitic imidazolate framework membranes by an ammoniaassisted strategy显示文摘塑造象金属那样的水晶的多孔的材料器官的框架(MOF ) 和沸石进二维(2D ) nanosheet 形成为开发高效的分子的 sieving 膜是高度合乎需要的。然而,常规脱落免职为 nanosheet MOF 管状的膜的大规模制造复杂、挑战性。第一次,这里,我们由 ZnO 自我变换和氨帮助报导一种直接生长技术制作 zeolitic imidazolate 框架(ZIF ) 膜在多孔的空纤维底层上由 2D nanosheets 组成;膜对大规模工业煤气的分离过程合适。为 ZIF nanosheet 膜的建议制造过程在作为一个调节的人包含铵氢氧化物的一个 ligand 答案基于 ZnO 的预先扔的薄层的局部性的自我变换。产生 ZIF 2D nanosheet 管状的膜是高度面向的并且仅仅在厚度的 50 nm。它展出优秀分子的 sieving 性能,与为 H 2/CO2 分离的高 H 2 渗入和选择。这种技术为大规模分子的 sieving 应用在 MOF nanosheet 膜制造显示出大诺言。 | Yujia Li Lu Lin Min Tu Pei Nian Ashlee J. Howarth Omar K. Farha Jieshan Qiu Xiongfu Zhang | 2018 | Nano Research2018，11，4： | 6 |
| 5 | Transurethral resection of the prostate is an independent risk factor for biochemical recurrence after radical prostatectomy for prostate cancer显示文摘Biochemical recurrence(BCR)is important for measuring the oncological outcomes of patients who undergo radical prostatectomy(RP).Whether transurethral resection of the prostate(TURP)has negative postoperative effects on oncological outcomes remains controversial.The primary aim of our retrospective study was to determine whether a history of TURP could affect the postoperative BCR rate.We retrospectively reviewed patients with prostate cancer(PCa)who had undergone RP between January 2009 and October 2017.Clinical data on age,prostate volume,serum prostate-specific antigen levels(PSA),biopsy Gleason score(GS),metastasis stage(TNM),D’Amico classification,and American Society of Anesthesiologists(ASA)classification were collected.Statistical analyses including Cox proportional hazard models and sensitivity analyses which included propensity score matching,were performed,and the inverse-probability-of-treatment-weighted estimator and standardized mortality ratio-weighted estimator were determined.We included 1083 patients,of which 118 had a history of TURP.Before matching,the non-TURP group differed from the TURP group with respect to GS(P=0.047),prostate volume(mean:45.19 vs 36.00 ml,P<0.001),and PSA level(mean:29.41 vs 15.11 ng ml?1,P=0.001).After adjusting for age,PSA level,T stage,N stage,M stage,and GS,the TURP group showed higher risk of BCR(hazard ratio[HR]:2.27,95%confidence interval[CI]:1.13–3.94,P=0.004).After matching(ratio 1:4),patients who underwent TURP were still more likely to develop BCR according to the adjusted propensity score(HR:2.00,95%CI:1.05–3.79,P=0.034).Among patients with PCa,those with a history of TURP were more likely to develop BCR after RP. | Kun Jin Shi Qiu Xin-Yang Liao Xiao-Nan Zheng Xiang Tu Lian-Sha Tang Lu Yang Qiang Wei | 2020 | Asian Journal of Andrology2020，22，2： | 4 |
| 6 | Electrophysiological evidence of personal experiences in the great Sichuan earthquake impacting on selective attention显示文摘Event-related brain potentials(ERPs) were measured when 24 Chinese subjects performed the earthquake color-matching Stroop task.All of them have experienced the great Sichuan earthquake(5.12),with 12 subjects in each of Chengdu city and Chongqing city(different earthquake experiences) groups.The behavioral data showed that the earthquake Stroop task yielded robust the earthquake interference effect as indexed by longer RT for earthquake-related(Related) words than earthquake-unrelated(Unrelated) words only in the Chengdu group.Scalp ERP analysis also revealed the neurophysiological substrate of the interference effect:a greater positivity(P350-450) in Related words as compared to Unrelated words was found between 350 and 450 ms post-stimulus over fronto-central scalp regions in the Chengdu group,while the interference effect was not found in the Chongqing group.The P350-450 might reflect an earthquake experience interference,but also attention enhancing,effect of earthquake-related words.Dipole source analysis of the difference wave(Related-Unrelated) showed that a generator was localized in the parahippocampal gyrus,which was possibly associated with flashbulb memory(personal earthquake experience).The results indicated that different personal earthquake experiences might be critical in engaging the neural mechanisms that underlie the modulation of selective attention. | QIU Jiang1,2,LI Hong1,2,ZHANG QingLin1,2,HUANG LiHui2,GUO YaQiao2,TU Shen2,WANG Ting2 & WEI DongTao2 1 Key Laboratory of Cognition and Personality(SWU),Ministry of Education,Chongqing 400715,China 2 School of psychology,Southwest University,Chongqing 400715,China | 2009 | Science China(Life Sciences)2009，52，7： | 4 |
| 7 | Microsurgical denervation of the spermatic cord for treatment of idiopathic chronic orchialgia显示文摘 | TU Xiang-an GAO Yong ZHANG Ya-dong ZHUANG Jin-tao ZHAO Ji-quan ZHAO Liang-yun ZHAO Liang SUN Xiang-zhou QIU Shao-peng DENG Chun-hua | 2012 | Chinese Medical Journal2012，，15： | 4 |
| 8 | Nitric oxide-generating compound and bio-clickable peptide mimic for synergistically tailoring surface anti-thrombogenic and anti-microbial dual-functions显示文摘Application of extracorporeal circuits and indwelling medical devices has saved many lives.However,it is accompanied with two major complications:thrombosis and infection.To address this issue,we apply therapeutic nitric oxide gas(NO)and antibacterial peptide for synergistically tailoring such devices for surface anti-thrombogenic and antifouling dual functions.Such functional surface is realized by stepwise conjugation of NO-generating compound of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid(DOTA)chelated copper ions(Cu-DOTA)and dibenzylcyclooctyne-(DBCO-)modified antimicrobial peptide based on carbodiimide and click chemistry respectively.The integration of peptide and Cu-DOTA grants the modified surface the ability to not only efficiently inhibit bacterial growth,but also catalytically generate NO from endogenous s-nitrosothiols(RSNO)to reduce adhesion and activation of platelets,preventing the formation of thrombus.We envision that the stepwise synergistic modification strategy by using anticoagulant NO and antibacterial peptide would facilitate the surface multifunctional engineering of extracorporeal circuits and indwelling medical devices,with reduced clinical complications associated with thrombosis and infection. | Han Yu Shaoxing Yu Hua Qiu Peng Gao Yingzhong Chen Xin Zhao Qiufen Tu Minggang Zhou Lin Cai Nan Huang Kaiqin Xiong Zhilu Yang | 2021 | Bioactive Materials2021，6，6： | 3 |
| 9 | Reducing nitrogen application with dense planting increases nitrogen use efficiency by maintaining root growth in a double-rice cropping system显示文摘Rational nitrogen(N) application can greatly increase rice(Oryza sativa L.) yield. However, excessive N input can lead not only to low N use efficiency(NUE) but also to severe environmental pollution.Reducing N application rate with a higher planting density(RNHD) is recommended to maintain rice yield and improve NUE. The effects of RNHD on fertilizer N fate and rice root growth traits remain unclear. We accordingly conducted a two-year field experiment to investigate the influence of RNHD on rice yield, fertilizer 15N fate, and root growth in a double-rice cropping system in China. In comparison with the conventional practice of high N application with sparse planting, RNHD resulted in similar yield and biomass production as well as plant N uptake. RNHD increased agronomic NUEs by 23.3%–31.9%(P < 0.05) and N recovery efficiency by 17.4%–24.1%(P < 0.05). RNHD increased fertilizer 15N recovery rate by 14.5%–34.7%(P < 0.05), but reduced15 N retention rate by 9.2%–12.0%(P < 0.05). Although a reduced N rate led to significantly reduced root length, surface area, volume, and biomass, these root traits were significantly increased by higher planting density. RNHD did not affect these root morphological traits and reduced activities of nitrate reductase(NR) and glutamine synthetase(GS) only at tillering stage. Plant N uptake was significantly positively correlated with these root traits, but not correlated with NR and GS activities. Together, these findings show that reducing N application with dense planting can lead to high plant N uptake by maintaining rice root growth and thus increase NUE. | Jin Chen Xiangcheng Zhu Jiang Xie Guoqiang Deng Tianhua Tu Xianjiao Guan Zhen Yang Shan Huang Xianmao Chen Caifei Qiu Yinfei Qian Caihong Shao Minggang Xu Chunrui Peng | 2021 | The Crop Journal2021，9，4： | 3 |
| 10 | Effect of pulsatile perfusion during cardiopulmonary bypass in terms of radial artery sphygmogram显示文摘OBJECTIVE: To investigate a quantitative method for using radial artery pulse waveforms to assess the effect of pulsatile flow during cardiopulmonary bypass(CPB).METHODS: A total of 34 adults with heart disease who underwent open-heart surgery between April2010 and January 2011 were randomized into a pulsatile perfusion group(n=17) and a non-pulsatile perfusion group(n=17). Radial arterial pulse waveforms of pulsatile and non-pulsatile perfusion patients were observed and compared before and during CPB.RESULTS: No pulse waveform could be detected at patients' radial artery in both groups when the aorta was cross-clamped. Pulse waveforms could be detected at pulsatile perfusion patients' radial artery, but could not be detected at non-pulsatile perfusion patients' radial artery during CPB. Additionally, patients' pulse waveforms during pulsatile perfusion were lower than those before the operation.CONCLUSION: Our findings indicate that radial artery sphygmogram can be used as a valid indicator to evaluate the effectiveness of pulsatile perfusion during CPB. | Zhifeng Zhang Jiatuo Xu Enyuan Zhu Qi Zhang Lu Yu Yongbing Qiu Jianguo Tang Zhaofu Fei Xin Li Liping Tu Chouping Han Ying Liu Zhen Guo Changle Zhou Meiyu Shi Yingxin Qian Yimin Bao Xinming Ji | 2014 | Journal of Traditional Chinese Medicine2014，34，6： | 2 |
| 11 | Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles显示文摘The spread of coronavirus disease 2019(COVID-19)throughout the world has resulted in stressful healthcare burdens and global health crises.Developing an effective measure to protect people from infection is an urgent need.The blockage of interaction between angiotensin-converting enzyme 2(ACE2)and S protein is considered an essential target for anti-severe acute respiratory syndrome coronavirus 2(SARS-Co V-2)drugs.A full-length ACE2 protein could be a potential drug to block early entry of SARS-Co V-2 into host cells.In this study,a therapeutic strategy was developed by using extracellular vesicles(EVs)with decoy receptor ACE2 for neutralization of SARS-Co V-2.The EVs embedded with engineered ACE2(EVs-ACE2)were prepared;the EVs-ACE2 were derived from an engineered cell line with stable ACE2 expression.The potential effect of the EVs-ACE2 on anti-SARS-Co V-2 was demonstrated by both in vitro and in vivo neutralization experiments using the pseudovirus with the S protein(S-pseudovirus).EVs-ACE2 can inhibit the infection of S-pseudovirus in various cells,and importantly,the mice treated with intranasal administration of EVs-ACE2 can suppress the entry of S-pseudovirus into the mucosal epithelium.Therefore,the intranasal EVs-ACE2 could be a preventive medicine to protect from SARS-Co V-2 infection.This EVs-based strategy offers a potential route to COVID-19 drug development. | Canhao Wu Qin Xu Huiyuan Wang Bin Tu Jiaxin Zeng Pengfei Zhao Mingjie Shi Hong Qiu Yongzhuo Huang | 2022 | Acta Pharmaceutica Sinica B2022，12，3： | 2 |
| 12 | Validation of the simplified criteria for diagnosis of autoimmune hepatitis in Chinese patients显示文摘 | Dekai Qiu Qixia Wang Hui Wang Qing Xie Guoqing Zang Hong Jiang Chuantao Tu Jinsheng Guo Shuncai Zhang Jianshe Wang Yi Lu Ying Han Lei Shen Xiaoyu Chen Xiqi Hu Xiaojin Wang Chengwei Chen Qingchun Fu Xiong Ma | 2010 | Journal of Hepatology2010，，： | 2 |
| 13 | Induction of innate lymphoid cell-de- rived interleukin-22 by the transcription factor STAT3 mediates pro- tection against intestinal infection 显示文摘 | Guo XH Qiu J Tu T | 2014 | Immunity2014，40，1： | 1 |
| 14 | Isothermal reduction of titanomagnetite concentrates containing coal显示文摘The isothermal reduction of the Panzhihua titanomagnetite concentrates(PTC)briquette containing coal under argon atmosphere was investigated by thermogravimetry in an electric resistance furnace within the temperature range of 1250-1350°C.The samples reduced in argon at 1350°C for different time were examined by X-ray diffraction(XRD)analysis.Model-fitting and model-free methods were used to evaluate the apparent activation energy of the reduction reaction.It is found that the reduction rate is very fast at the early stage,and then,at a later stage,the reduction rate becomes slow and decreases gradually to the end of the reduction.It is also observed that the reduction of PTC by coal depends greatly on the temperature.At high temperatures,the reduction degree reaches high values faster and the final value achieved is higher than at low temperatures.The final phase composition of the reduced PTC-coal briquette consists in iron and ferrous-pseudobrookite(FeTi2O5),while Fe2.75Ti0.25O4,Fe2.5Ti0.5O4,Fe2.25Ti0.75O4,ilmenite(FeTiO3)and wustite(FeO)are intermediate products.The reaction rate is controlled by the phase boundary reaction for reduction degree less than 0.2 with an apparent activation energy of about 68 kJ·mol-1and by three-dimensional diffusion for reduction degree greater than 0.75 with an apparent activation energy of about134 kJ·mol-1.For the reduction degree in the range of 0.2-0.75,the reaction rate is under mixed control,and the activation energy increases with the increase of the reduction degree. | Tu Hu Xue-wei Lü Chen-guang Bai Gui-bao Qiu | 2014 | International Journal of Minerals,Metallurgy and Materials2014，21，2： | 1 |
| 15 | Heating control strategy for variable refrigerant flow air conditioning system with multi-module outdoor units显示文摘 | Tu Qiu Mao Shoubo Feng Ziping | | Energy and Buildings0，，： | 1 |
| 16 | Generalized Gr?tzsch ring function and generalized elliptic integrals显示文摘In this paper, we study the quotient of hypergeometric functions μ_a(r) in the theory of Ramanujan's generalized modular equation for a ∈(0, 1/2]. Several new inequalities are given for this and related functions. Our main results complement and generalize some known results in the literature. | MA Xiao-yan QIU Song-liang TU Guo-yan | 2016 | Applied Mathematics(A Journal of Chinese Universities)2016，31，4： | 1 |
| 17 | Acceptance,efficacy,and side effects of Norplant implants in four counties in north China显示文摘 | Tu P Qiu S Fang H | 1997 | Stud Fam Plann1997，28，2： | 1 |
| 18 | The study of a self-frequency-doubling laser crystal Nd^3+:GdAl3(BO3)4显示文摘 | Tu Chaoyang Qiu Minwang Huang Yichuan Chen Xueyuan Jiang Aidong Luo Zundu | 2000 | Journal of Crystal Growth2000，208，14： | 1 |
| 19 | Genetic diversity and divergence in Chinese yak (Bos grunniens) populations infeted from blood protein electrophoresis显示文摘 | Tu Zheng-Chao Zhang Ya-Ping Qiu Huai | 1997 | BiochemiGenet1997，35，1： | 1 |
| 20 | Recent progress in perovskite solar cells:from device to commercialization显示文摘Perovskite solar cells(PSCs) are undergoing rapid development and the power conversion efficiency reaches 25.7% which attracts increasing attention on their commercialization recently.In this review,we summarized the recent progress of PSCs based on device structures,perovskite-based tandem cells,large-area modules,stability,applications and industrialization.Last,the challenges and perspectives are discussed,aiming at providing a thrust for the commercialization of PSCs in the near future. | Xinhui Luo Xuesong Lin Feng Gao Yang Zhao Xiaodong Li Liqing Zhan Zexiong Qiu Jin Wang Cong Chen Lei Meng Xiaofeng Gao Yu Zhang Zijian Huang Rundong Fan Huifen Liu Yanrun Chen Xiaoxue Ren Jiahong Tang Chun-Hao Chen Dong Yang Yongguang Tu Xiao Liu Dongxue Liu Qing Zhao Jingbi You Junfeng Fang Yongzhen Wu Hongwei Han Xiaodan Zhang Dewei Zhao Fuzhi Huang Huanping Zhou Yongbo Yuan Qi Chen Zhaokui Wang Shengzhong(Frank)Liu Rui Zhu Jotaro Nakazaki Yongfang Li Liyuan Han | 2022 | Science China Chemistry2022，65，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员